Research Topics
Genomes and GenesSpecies | Kristien VerdonckSummaryAffiliation: Institute of Tropical Medicine Country: Belgium Publications
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Detail Information
Publications
HTLV-1 infection is frequent among out-patients with pulmonary tuberculosis in northern Lima, PeruK Verdonck
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Int J Tuberc Lung Dis 11:1066-72. 2007..Tuberculosis (TB) and human T-lymphotropic virus 1 (HTLV-1) are frequent in Peru. The prevalence of HTLV-1 among Peruvian TB patients is unknown...
HTLV-1 infection is associated with a history of active tuberculosis among family members of HTLV-1-infected patients in PeruK Verdonck
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Epidemiol Infect 136:1076-83. 2008..3-5.1, for siblings vs. spouses of index cases). In conclusion, HTLV-1 infection may increase the susceptibility to active TB. In populations where both infections are frequent, such an association could affect the dynamics of TB...
Human T-lymphotropic virus 1: recent knowledge about an ancient infectionKristien Verdonck
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Lancet Infect Dis 7:266-81. 2007..The understanding of the interaction between virus and host response has improved markedly, but there are still no clear surrogate markers for prognosis and there are few treatment options...
Evaluation of host genetic and viral factors as surrogate markers for HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian HTLV-1-infected patientsMichael Talledo
Institute of Tropical Medicine Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
J Med Virol 82:460-6. 2010..A logistic model containing PVL, age, gender, and HLA-A*02 provided the best predictive ability in the Peruvian cohort (AUC = 0.79). J. Med. Virol. 82:460-466, 2010. (c) 2010 Wiley-Liss, Inc...
Risk factors associated with diarrhea among international visitors to Cuzco, PeruMiguel M Cabada
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Am J Trop Med Hyg 75:968-72. 2006..04). Remaining in Cuzco < 1 week was a protective factor (OR: 0.58). TD is common among travelers to Cuzco. This study suggests that conventional recommendations are not invariably effective at decreasing TD...
Possible implication of NFKB1A and NKG2D genes in susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian patients infected with HTLV-1Michael Talledo
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
J Med Virol 84:319-26. 2012..Further replication studies in independent HTLV-1 patient groups should validate further these associations...
IFN-gamma production in response to Tax 161-233, and frequency of CD4+ Foxp3+ and Lin HLA-DRhigh CD123+ cells, discriminate HAM/TSP patients from asymptomatic HTLV-1-carriers in a Peruvian populationIvan Best
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Immunology 128:e777-86. 2009....
Comparison of three ELISAs for the routine diagnosis of human T-lymphotropic virus infection in a high-prevalence setting in PeruKristien Verdonck
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Av Honorio Delgado 430, Lima 31, Peru
Trans R Soc Trop Med Hyg 103:420-2. 2009..Six samples had discordant ELISA; Murex gave one false-negative result, Ortho two and Platelia one. In high-prevalence settings, it is recommended to test samples with two ELISAs before considering them HTLV-seronegative...
Frequent HTLV-1 infection in the offspring of Peruvian women with HTLV-1-associated myelopathy/tropical spastic paraparesis or strongyloidiasisEduardo Gotuzzo
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Avenida Honorio Delgado 430, Lima, Peru
Rev Panam Salud Publica 22:223-30. 2007....
Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in PeruMichael Talledo
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Hum Immunol 71:804-8. 2010..Our study did not reveal significant associations between KIR genes and HLA-Cw groups and HAM/TSP or PVL. However, because our study was powered to detect only larger effects, additional studies using larger cohorts are needed...
Sexual behavior, knowledge of STI prevention, and prevalence of serum markers for STI among tour guides in Cuzco/PeruMiguel M Cabada
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
J Travel Med 14:151-7. 2007..The purpose of this study was to explore the sexual behavior, knowledge of STI prevention, and prevalence of serum markers of selected STIs in tour guides in Cuzco/Peru...
SYBR Green-based quantitation of human T-lymphotropic virus type 1 proviral load in Peruvian patients with neurological disease and asymptomatic carriers: influence of clinical status, sex, and familial relatednessVanessa Adaui
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
J Neurovirol 12:456-65. 2006....
Short communication an interferon-γ ELISPOT assay with two cytotoxic T cell epitopes derived from HTLV-1 tax region 161-233 discriminates HTLV-1-associated myelopathy/tropical spastic paraparesis patients from asymptomatic HTLV-1 carriers in a Peruvian poIvan Best
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
AIDS Res Hum Retroviruses 27:1207-12. 2011..The HLA-A*6801 allele, which is predicted to bind to the Tax 181-193 peptide, was overpresented in the HAM/TSP patients tested...
Predictors of CD4+ cell count response and of adverse outcome among HIV-infected patients receiving highly active antiretroviral therapy in a public hospital in PeruDiego López de Castilla
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Int J Infect Dis 12:325-31. 2008..Our aim was to investigate CD4+ cell recovery and adverse outcome after highly active antiretroviral therapy (HAART) under the Peruvian National Program for HIV...
Pretravel health advice among international travelers visiting Cuzco, PeruMiguel M Cabada
Instituto de Medicina Tropical, Lima, Peru
J Travel Med 12:61-5. 2005..Recommendations addressed for specific health risks, such as altitude sickness prophylaxis, were received by few travelers...
Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigenMartin Montes
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
PLoS Negl Trop Dis 3:e456. 2009..We hypothesize that HTLV-1 leads to dissemination of Strongyloides stercoralis infection by augmenting regulatory T cell numbers, which in turn down regulate the immune response to the parasite...
Association between onychodystrophy and human T-lymphotropic virus type 1 infectionErick F Mayer
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru Electronic address
Int J Infect Dis 17:e312-6. 2013..To assess the association between human T-lymphotropic virus type 1 (HTLV-1) infection and onychodystrophy...
[Researchers training in the context of the collaborative projects: experiences of Instituto de Medicina Tropical "Alexander von Humbolt", Universidad Peruana Cayetano Heredia]Eduardo Gotuzzo
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Rev Peru Med Exp Salud Publica 27:419-27. 2010....
Clinical evaluation of a 16S ribosomal RNA polymerase chain reaction test for the diagnosis of lymph node tuberculosisFernando Osores
Institute of Tropical Medicine Alexander von Humboldt, Lima, Peru
Clin Infect Dis 43:855-9. 2006..We evaluated the accuracy of the Roche Amplicor Mycobacterium tuberculosis PCR test with lymph node aspirate and biopsy samples...
Sexual behavior in travelers visiting CuzcoMiguel M Cabada
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
J Travel Med 10:214-8. 2003....
HTLV in the Americas: challenges and perspectivesAnna Bárbara F Carneiro-Proietti
Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil
Rev Panam Salud Publica 19:44-53. 2006..For this reason, public health interventions aimed at counseling and educating high-risk individuals and populations are of vital importance. In the Americas this is especially important in the areas of high prevalence...
Scaling-up highly active antiretroviral therapy (HAART) in Peru: problems on the horizonJuan Echevarria
J Acquir Immune Defic Syndr 43:625-6. 2006
