Robert Colebunders

Summary

Affiliation: Institute of Tropical Medicine
Country: Belgium

Publications

  1. ncbi request reprint Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment
    Robert Colebunders
    Institute of Tropical Medicine Antwerp, Antwerp, B 2000, Belgium
    J Infect Dis 196:S148-53. 2007
  2. pmc Increased risk for Entamoeba histolytica infection and invasive amebiasis in HIV seropositive men who have sex with men in Taiwan
    Chien Ching Hung
    Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    PLoS Negl Trop Dis 2:e175. 2008
  3. pmc The efficacy of a brief intervention to reduce alcohol misuse in patients with HIV in South Africa: study protocol for a randomized controlled trial
    Diana Huis In 't Veld
    Department of Epidemiology and Social Medicine, University of Antwerp, Universiteitsplein, Antwerp Wilrijk, Belgium
    Trials 13:190. 2012
  4. pmc Relatively low primary drug resistant tuberculosis in southwestern Ethiopia
    Gemeda Abebe
    Department of Medical Laboratory Sciences and Pathology, Jimma University, Jimma, Ethiopia
    BMC Res Notes 5:225. 2012
  5. pmc Acceptability of HIV self-testing: a systematic literature review
    Janne Krause
    Institute of Tropical Medicine and International Health, Charite Universitatsmedizin, Berlin, Germany
    BMC Public Health 13:735. 2013
  6. pmc Change in quality of life: a follow up study among patients with HIV infection with and without TB in Ethiopia
    Amare Deribew
    Department of Epidemiology, Jimma University, Jimma, Ethiopia
    BMC Public Health 13:408. 2013
  7. pmc Predictors of condom use and refusal among the population of Free State province in South Africa
    Thoovakkunon Moorkoth Chandran
    Department of Health, Free State, Bloemfontein, 9300, South Africa
    BMC Public Health 12:381. 2012
  8. pmc Tuberculosis lymphadenitis in Southwest Ethiopia: a community based cross-sectional study
    Gemeda Abebe
    Department of Medical Laboratory Sciences and Pathology, Jimma University, Jimma, Ethiopia
    BMC Public Health 12:504. 2012
  9. doi request reprint Antiretroviral treatment in low-resource settings: what has changed in the last 10 years and what needs to change in the coming years?
    Mandana Mehta
    Institute of Tropical Medicine, 155, Nationalestraat, Antwerpen 2000, Belgium
    Expert Rev Anti Infect Ther 10:1287-96. 2012
  10. pmc Prevalence of pulmonary TB and spoligotype pattern of Mycobacterium tuberculosis among TB suspects in a rural community in Southwest Ethiopia
    Amare Deribew
    Department of Epidemiology, Jimma University, Jimma, Ethiopia
    BMC Infect Dis 12:54. 2012

Detail Information

Publications157 found, 100 shown here

  1. ncbi request reprint Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment
    Robert Colebunders
    Institute of Tropical Medicine Antwerp, Antwerp, B 2000, Belgium
    J Infect Dis 196:S148-53. 2007
    ..Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment...
  2. pmc Increased risk for Entamoeba histolytica infection and invasive amebiasis in HIV seropositive men who have sex with men in Taiwan
    Chien Ching Hung
    Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    PLoS Negl Trop Dis 2:e175. 2008
    ..Incidence of Entamoeba histolytica infection and clinical manifestations and treatment response of invasive amebiasis (IA) in HIV-infected patients have rarely been investigated before...
  3. pmc The efficacy of a brief intervention to reduce alcohol misuse in patients with HIV in South Africa: study protocol for a randomized controlled trial
    Diana Huis In 't Veld
    Department of Epidemiology and Social Medicine, University of Antwerp, Universiteitsplein, Antwerp Wilrijk, Belgium
    Trials 13:190. 2012
    ..This study aims to determine the prevalence of alcohol use and other risk factors in a sample of primary care patients with HIV in South Africa and to assess a brief intervention to reduce the use of alcohol in this group...
  4. pmc Relatively low primary drug resistant tuberculosis in southwestern Ethiopia
    Gemeda Abebe
    Department of Medical Laboratory Sciences and Pathology, Jimma University, Jimma, Ethiopia
    BMC Res Notes 5:225. 2012
    ..We conducted a study at Jimma University specialized hospital in southwest Ethiopia among new cases of smear positive TB patients to determine the pattern of resistance to first-line drugs...
  5. pmc Acceptability of HIV self-testing: a systematic literature review
    Janne Krause
    Institute of Tropical Medicine and International Health, Charite Universitatsmedizin, Berlin, Germany
    BMC Public Health 13:735. 2013
    ..We evaluated the acceptability of HST and the benefits and challenges linked to the introduction of HST...
  6. pmc Change in quality of life: a follow up study among patients with HIV infection with and without TB in Ethiopia
    Amare Deribew
    Department of Epidemiology, Jimma University, Jimma, Ethiopia
    BMC Public Health 13:408. 2013
    ..We conducted a study to assess the change in QoL over a 6-months period and its predictors among HIV-infected patients with and without TB in Ethiopia...
  7. pmc Predictors of condom use and refusal among the population of Free State province in South Africa
    Thoovakkunon Moorkoth Chandran
    Department of Health, Free State, Bloemfontein, 9300, South Africa
    BMC Public Health 12:381. 2012
    ..This study investigated the extent and predictors of condom use and condom refusal in the Free State province in South Africa...
  8. pmc Tuberculosis lymphadenitis in Southwest Ethiopia: a community based cross-sectional study
    Gemeda Abebe
    Department of Medical Laboratory Sciences and Pathology, Jimma University, Jimma, Ethiopia
    BMC Public Health 12:504. 2012
    ..Therefore, we conducted a study to estimate the prevalence of TB lymphadenitis in Southwest Ethiopia...
  9. doi request reprint Antiretroviral treatment in low-resource settings: what has changed in the last 10 years and what needs to change in the coming years?
    Mandana Mehta
    Institute of Tropical Medicine, 155, Nationalestraat, Antwerpen 2000, Belgium
    Expert Rev Anti Infect Ther 10:1287-96. 2012
    ..In this article, the authors provide an overview of the significant advances made in improving access to antiretrovirals in low-resource settings, as well as the challenges facing new approaches to ART in the next decade...
  10. pmc Prevalence of pulmonary TB and spoligotype pattern of Mycobacterium tuberculosis among TB suspects in a rural community in Southwest Ethiopia
    Amare Deribew
    Department of Epidemiology, Jimma University, Jimma, Ethiopia
    BMC Infect Dis 12:54. 2012
    ..We conducted a community based survey to estimate the prevalence of pulmonary TB and spoligotype pattern of the Mycobacterium tuberculosis isolates in Southwest Ethiopia...
  11. pmc Pulmonary cystic disease in HIV positive individuals in the Democratic Republic of Congo: three case reports
    Steven Fj Callens
    School of Public Health, University of North Carolina at Chapel Hill, USA
    J Med Case Reports 1:101. 2007
    ..In this report, we describe three HIV-infected individuals (one woman and two children) presenting with extensive pulmonary cystic disease...
  12. pmc Tuberculosis and HIV co-infection: its impact on quality of life
    Amare Deribew
    Department of Epidemiology, Jimma University, Jimma, Ethiopia
    Health Qual Life Outcomes 7:105. 2009
    ..Very little is known about the quality of life of tuberculosis (TB) and HIV co-infected patients. In this study in Ethiopia, we compared the quality of life HIV positive patients with and without TB...
  13. pmc Prejudice and misconceptions about tuberculosis and HIV in rural and urban communities in Ethiopia: a challenge for the TB/HIV control program
    Amare Deribew
    Department of Epidemiology and Social Medicine, University of Antwerp, Antwerp, Belgium
    BMC Public Health 10:400. 2010
    ..In Ethiopia, where HIV and tuberculosis (TB) are very common, little is known about the prejudice and misconceptions of rural communities towards People living with HIV/AIDS (PLHA) and TB...
  14. pmc Common mental disorders in TB/HIV co-infected patients in Ethiopia
    Amare Deribew
    Department of Epidemiology, Jimma University, Jimma, Ethiopia
    BMC Infect Dis 10:201. 2010
    ..The relationship between TB/HIV co-infection and common mental disorders (CMD) has been scarcely investigated. In this study, we compared the occurrence of CMD in TB/HIV co-infected and non-co-infected HIV patients in Ethiopia...
  15. pmc Computed CD4 percentage as a low-cost method for determining pediatric antiretroviral treatment eligibility
    Steven F J Callens
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, USA
    BMC Infect Dis 8:31. 2008
    ..The performance of the WHO recommendations for pediatric antiretroviral treatment (ART) in resource poor settings is insufficiently documented in routine care...
  16. pmc Is vitamin D deficiency involved in the immune reconstitution inflammatory syndrome?
    Anali Conesa-Botella
    Institute of Tropical Medicine, Department of Clinical Sciences, Antwerp, Belgium
    AIDS Res Ther 6:4. 2009
    ..The active form of vitamin D, 1,25-dihydroxyvitamin D, is a key player in the clearance of pathogens and influences the level of inflammation and macrophage activation...
  17. ncbi request reprint Imported viral haemorrhagic fever with a potential for person-to-person transmission: review and recommendations for initial management of a suspected case in Belgium
    R Colebunders
    Departement Klinische Wetenschappen, Instituut voor Tropische Geneeskunde Nationalestraat 155, B 2000 Antwerpen
    Acta Clin Belg 57:233-40. 2002
    ..Using universal precautions for handling blood and body fluids and barrier nursing techniques there is little risk that if a patient with viral haemorrhagic fever arrives in Belgium there will be secondary cases...
  18. ncbi request reprint A new model to monitor the virological efficacy of antiretroviral treatment in resource-poor countries
    Robert Colebunders
    Infectious Disease Institute, Faculty of Medicine, Makerere University, Kampala, Uganda
    Lancet Infect Dis 6:53-9. 2006
    ..We believe that this model can make an accurate diagnosis of treatment failure in most patients. However, operational research is needed to assess whether this strategy works in practice...
  19. ncbi request reprint Lessons Learned From 2 Patients With Multidrug-Resistant HIV-1 Infection Successfully Treated With a Darunavir-Containing Antiretroviral Treatment Regimen
    Robert Colebunders
    Institute of Tropical Medicine, Antwerp, Belgium, University Hospital Antwerp, Antwerp, Belgium
    J Int Assoc Physicians AIDS Care (Chic) 6:203-5. 2007
    ..They discuss the availability of several new treatment options such as darunavir, etravirine, integrase, and CCR5 inhibitors for patients with multidrug-resistant viruses...
  20. doi request reprint Drug-resistant TB and HIV in resource-limited settings: what TB/HIV programmes can learn from each other
    R Colebunders
    Institute of Tropical Medicine, Antwerp, Belgium
    Trop Med Int Health 13:1204-7. 2008
    ..On the other hand, antiretroviral roll-out programmes should learn from the genesis of the MDR-TB problem; laboratory monitoring should be enhanced and compliance optimized to avoid the acquisition of additional drug resistance in HIV...
  21. ncbi request reprint First-line antiretroviral therapy in Africa--how evidence-base are our recommendations?
    Robert Colebunders
    The Infectious Disease Institute, Faculty of Medicine, Makerere University, Kampala, Uganda
    AIDS Rev 7:148-54. 2005
    ..Most importantly, more HIV clinical trials need to be conducted in Africa, and African cohorts of patients on antiretroviral therapy need to be established in order to develop recommendations that are evidence based...
  22. pmc Vena cava inferior thrombosis detected by venous hum: a case report
    Robert Colebunders
    Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium
    J Med Case Reports 1:67. 2007
    ..ABSTRACT: We describe a patient in which a venous hum, heard during abdominal auscultation, lead to the diagnosis of a vena cava inferior thrombosis...
  23. ncbi request reprint Organisation of health care during an outbreak of Marburg haemorrhagic fever in the Democratic Republic of Congo, 1999
    Robert Colebunders
    Medecins Sans Frontieres, Duprestraat 94, B 1090 Brussel, Belgium
    J Infect 48:347-53. 2004
    ..In contrast to Ebola outbreaks, there was little panic among health care workers and the general public in Durba and all health services remained operational...
  24. pmc Clinical presentation and aetiologies of acute or complicated headache among HIV-seropositive patients in a Ugandan clinic
    Michael Katwere
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    J Int AIDS Soc 12:21. 2009
    ..abstract:..
  25. ncbi request reprint Merkel cell carcinoma and multiple basal cell carcinoma in an African albino woman with HIV infection
    R Colebunders
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    HIV Med 5:452-4. 2004
    ..Chemotherapy and radiotherapy were only temporarily successful. She died shortly after surgery was performed to remove the tumour...
  26. ncbi request reprint A frontal mucocele caused by an immune reconstitution inflammatory syndrome in a patient with HIV infection
    B Colebunders
    University of Antwerp, Antwerp, Belgium
    Rhinology 46:243-5. 2008
    ..With the increasing numbers of persons living with HIV infection and the increased use of HAART it is expected that in the future more otolaryngological manifestations of IRIS will be detected...
  27. ncbi request reprint Antiretroviral treatments used among adults with HIV infection in Europe
    R Colebunders
    Institute of Tropical Medicine, Antwerpen, Belgium
    AIDS Care 13:5-14. 2001
    ..Between 1996 and 1997, many persons with HIV infection in Europe received a suboptimal ARV treatment regimen. Use of ARVs should be improved for intravenous drug users, persons with lower educational level and lower income...
  28. ncbi request reprint Assessment of the patient flow at the infectious diseases institute out-patient clinic, Kampala, Uganda
    R Colebunders
    Makerere University, Kampala, Uganda
    AIDS Care 19:149-51. 2007
    ..A similar methodology could be used to evaluate and compare health service delivery systems for persons with HIV infection in Africa in order to identify the most efficient models of care...
  29. ncbi request reprint Impact of new developments in antiretroviral treatment on AIDS prevention and care in resource-poor countries
    R Colebunders
    Institute of Tropical Medicine, Antwerp, Belgium
    AIDS Patient Care STDS 14:251-7. 2000
    ..The pressure on politicians and international donor agencies to provide ARVs to resource-poor countries should be used to increase overall healthcare budgets and to improve healthcare services in general...
  30. ncbi request reprint Hospital services for people with HIV infection in Flanders: patients' satisfaction
    R Colebunders
    Institute of Tropical Medicine, Antwerp, Belgium
    AIDS Care 13:191-6. 2001
    ..The multidisciplinary approach, offered by the Antwerp University Hospital, was widely appreciated by patients and could be used as an example for organizing patient care for other diseases...
  31. ncbi request reprint The use of complementary and alternative medicine by persons with HIV infection in Europe
    R Colebunders
    Institute of Tropical Medicine, Department of Clinical Sciences, Nationalestraat 155, B 2000 Antwerp, Belgium
    Int J STD AIDS 14:672-4. 2003
    ..The study shows that despite the availability of highly active antiretroviral therapy many people with HIV infection still take complementary and alternative medicine...
  32. ncbi request reprint A Belgian traveler who acquired yellow fever in the Gambia
    R Colebunders
    Institute of Tropical Medicine, B 2000 Antwerp, Belgium
    Clin Infect Dis 35:e113-6. 2002
    ....
  33. ncbi request reprint Unusual cutaneous lesions in two patients with visceral leishmaniasis and HIV infection
    R Colebunders
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    J Am Acad Dermatol 41:847-50. 1999
    ..In this patient the visceral leishmaniasis was finally cured with meglumine antimoniate, followed by pentacarinat isothianate as maintenance therapy in conjunction with highly active antiretroviral treatment...
  34. ncbi request reprint Tuberculosis immune reconstitution inflammatory syndrome in countries with limited resources
    R Colebunders
    Infectious Disease Institute, Faculty of Medicine, Makerere University, Kampala, Uganda
    Int J Tuberc Lung Dis 10:946-53. 2006
    ....
  35. doi request reprint Three-year outcome data of second-line antiretroviral therapy in Ugandan adults: good virological response but high rate of toxicity
    Barbara Castelnuovo
    Infectious Diseases Institute, Kampala, Uganda
    J Int Assoc Physicians AIDS Care (Chic) 8:52-9. 2009
    ..To evaluate the safety and virological response to lopinavir/ritonavir containing second-line therapy after failing a first line nonnucleoside reverse transcriptase inhibitor (NNRTI) based regimen...
  36. ncbi request reprint Predictors of long-term viral failure among ugandan children and adults treated with antiretroviral therapy
    Moses R Kamya
    Department of Medicine, Makerere University, Kampala, Uganda
    J Acquir Immune Defic Syndr 46:187-93. 2007
    ..We identified predictors of viral failure and documented genotypic mutations in a subset of patients with viral failure after 12 months on antiretroviral therapy (ART)...
  37. pmc The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda
    Ponsiano Ocama
    Infectious Diseases Institute, Kampala, Uganda
    Afr Health Sci 8:8-12. 2008
    ..Liver diseases are common in patients with HIV due to viral hepatitis B and C co-infections, opportunistic infections or malignancies, antiretroviral drugs and drugs for opportunistic infections...
  38. pmc Strategies for optimizing clinic efficiency in a community-based antiretroviral treatment programme in Uganda
    Stella T Alamo
    Medical Department, Reach Out Mbuya HIV AIDS Initiative, P O Box 7303, Kampala, Uganda
    AIDS Behav 17:274-83. 2013
    ..Improved patient flow, patient and provider satisfaction and reduced waiting times allowed for service delivery to more patients using the same staff following the implementation of triage...
  39. ncbi request reprint Fever after a stay in the tropics: clinical spectrum and outcome in HIV-infected travelers and migrants
    Emmanuel Bottieau
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    J Acquir Immune Defic Syndr 48:547-52. 2008
    ..To investigate the epidemiology and clinical spectrum of fever in HIV-infected returning travelers and migrants...
  40. doi request reprint Impact of HIV-1 infection on the hematological recovery after clinical malaria
    Jean Pierre Van Geertruyden
    Department of Parasitology, and Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    J Acquir Immune Defic Syndr 50:200-5. 2009
    ..Anemia is the most frequent cytopenia in HIV-infected individuals and is often associated with malaria...
  41. ncbi request reprint Fever after a stay in the tropics: diagnostic predictors of the leading tropical conditions
    Emmanuel Bottieau
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    Medicine (Baltimore) 86:18-25. 2007
    ..The initial clinical and laboratory assessment can help in selecting appropriate investigations and empiric treatments for patients with imported fever...
  42. pmc Worsening and unmasking of tuberculosis in HIV-1 infected patients after initiating highly active anti-retroviral therapy in Uganda
    Joshua Baalwa
    Makerere University, Infectious Diseases Institute, Kampala, Uganda
    Afr Health Sci 8:190-5. 2008
    ..To determine the proportion of patients developing active tuberculosis (TB) versus that of patients who experience worsening of TB, after initiating highly active anti retroviral therapy (HAART)...
  43. ncbi request reprint Clinical spectrum, risk factors and outcome of immune reconstitution inflammatory syndrome in patients with tuberculosis-HIV coinfection
    William Worodria
    Department of Medicine, Makerere University College of Health Sciences, Mulago Hospital, Kampala, Uganda
    Antivir Ther 17:841-8. 2012
    ..Here, we aimed to determine the clinical spectrum, predictors and outcomes of paradoxical tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) in a resource-limited setting...
  44. pmc The impact of HIV-1 on the malaria parasite biomass in adults in sub-Saharan Africa contributes to the emergence of antimalarial drug resistance
    Jean Pierre Van Geertruyden
    Department of Parasitology, Unit of Epidemiology Institute of Tropical Medicine Antwerpen, Nationalestraat 155 B2000, Antwerpen, Belgium
    Malar J 7:134. 2008
    ..HIV-related immune-suppression increases the risk of malaria (infection, disease and treatment failure) and probably the circulating parasite biomass, favoring the emergence of drug resistance parasites...
  45. doi request reprint Urinary lipoarabinomannan as predictor for the tuberculosis immune reconstitution inflammatory syndrome
    Anali Conesa-Botella
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    J Acquir Immune Defic Syndr 58:463-8. 2011
    ..We investigated whether a positive urinary TB lipoarabinomannan (LAM) antigen enzyme-linked immunosorbent assay test before ART initiation was associated with development of paradoxical TB-IRIS...
  46. pmc Antiretroviral treatment-associated tuberculosis in a prospective cohort of HIV-infected patients starting ART
    William Worodria
    Department of Medicine, Mulago Hospital, College of Health Sciences, Makerere University, P O Box 7051, Kampala, Uganda
    Clin Dev Immunol 2011:758350. 2011
    ..In conclusion, with systematic TB screening (including culture and chest X-ray), the incidence of ART-associated TB is relatively low in settings with high HIV and TB prevalence...
  47. ncbi request reprint Infectious mononucleosis-like syndromes in febrile travelers returning from the tropics
    Emmanuel Bottieau
    Department of Clinical Sciences, Institute of Tropical Medicine Antwerp, Nationalestraat 155, 2000 Antwerp, Belgium
    J Travel Med 13:191-7. 2006
    ..All four pathogens should be systematically considered because early diagnosis should avoid unnecessary investigations and treatment and allow early intervention in case of primary HIV infection...
  48. ncbi request reprint CD4 T-cell count and HIV-1 infection in adults with uncomplicated malaria
    Jean Pierre Van Geertruyden
    Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
    J Acquir Immune Defic Syndr 43:363-7. 2006
    ..HIV-1-negative children with malaria have reversible lymphocyte and CD4 count decreases. We assessed the impact of malaria parasitemia on the absolute CD4 count in both HIV-1-infected and non-HIV-infected adults...
  49. ncbi request reprint An algorithm to optimize viral load testing in HIV-positive patients with suspected first-line antiretroviral therapy failure in Cambodia
    Lutgarde Lynen
    Departments of Clinical Sciences, Public Health, and Microbiology, Institute of Tropical Medicine, Antwerp, Belgium
    J Acquir Immune Defic Syndr 52:40-8. 2009
    ..To develop an algorithm for optimal use of viral load testing in patients with suspected first-line antiretroviral treatment (ART) failure...
  50. pmc An autopsy study describing causes of death and comparing clinico-pathological findings among hospitalized patients in Kampala, Uganda
    Janneke A Cox
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    PLoS ONE 7:e33685. 2012
    ..We conducted an autopsy study to describe and compare the clinical and autopsy causes of death and contributory findings in hospitalized HIV-infected and HIV-uninfected patients in Uganda...
  51. ncbi request reprint Etiology and outcome of fever after a stay in the tropics
    Emmanuel Bottieau
    Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium
    Arch Intern Med 166:1642-8. 2006
    ..Information on epidemiology and prognosis of imported fever is scarce and almost exclusively limited to hospital settings...
  52. ncbi request reprint Can response of a pruritic papular eruption to antiretroviral therapy be used as a clinical parameter to monitor virological outcome?
    Barbara Castelnuovo
    Infectious Diseases Institute, Kampala, Uganda
    AIDS 22:269-73. 2008
    ..A pruritic papular eruption (PPE) is a common skin manifestation observed in 12-46% of persons with HIV infection living in tropical countries...
  53. ncbi request reprint Imported non-Plasmodium falciparum malaria: a five-year prospective study in a European referral center
    Emmanuel Bottieau
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    Am J Trop Med Hyg 75:133-8. 2006
    ..In addition, the substantial relapse rate despite standard primaquine therapy supports the use of a higher dose of primaquine to eradicate P. vivax and P. ovale malaria effectively...
  54. ncbi request reprint A pharmacy-only refill program at a large HIV clinic in Uganda: experience and satisfaction of patients
    Alice Nakiwogga-Muwanga
    Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda
    J Int Assoc Provid AIDS Care 13:264-8. 2014
    ..The purpose of this study was to assess patients' experience and satisfaction with pharmacy-only refill program (PRP) and to compare those who were removed from the PRP with those still in the program...
  55. doi request reprint "It's better not to know": perceived barriers to HIV voluntary counseling and testing among sub-Saharan African migrants in Belgium
    Lazare Manirankunda
    Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium
    AIDS Educ Prev 21:582-93. 2009
    ..At level of service provision, provider initiated HIV testing including target group tailored counseling should be promoted...
  56. ncbi request reprint Are the best antiretrovirals being used in Africa?
    Laurence John
    Infectious Disease Institute, Mulago Hospital Complex, Kampala, Uganda
    J HIV Ther 11:11-5. 2006
  57. doi request reprint Evaluation of the GIDEON expert computer program for the diagnosis of imported febrile illnesses
    Emmanuel Bottieau
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    Med Decis Making 28:435-42. 2008
    ..The authors evaluate the performance of the expert system Global Infectious Diseases and Epidemiology Network (GIDEON) in diagnosing febrile illnesses occurring after a stay in the tropics...
  58. doi request reprint Improvement of the patient flow in a large urban clinic with high HIV seroprevalence in Kampala, Uganda
    B Castelnuovo
    Infectious Diseases Institute, PO Box 22418 Mulago Hill, Kampala, Uganda
    Int J STD AIDS 20:123-4. 2009
    ..A similar methodology could be used by other health services to evaluate and compare different models of care...
  59. pmc LPS-binding protein and IL-6 mark paradoxical tuberculosis immune reconstitution inflammatory syndrome in HIV patients
    Odin Goovaerts
    Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium
    PLoS ONE 8:e81856. 2013
    ..Here we aimed to investigate the innate nature of the cytokine response in TB-IRIS and to identify novel potential biomarkers...
  60. doi request reprint Partner-concurrency associated with herpes simplex virus 2 infection in young South Africans
    Chris Kenyon
    HIV STD Unit, Institute of Tropical Medicine, University of Antwerp, Antwerp, Belgium
    Int J STD AIDS 24:804-12. 2013
    ..We conclude that partner-concurrency is associated with increased HSV-2 seropositivity in women. ..
  61. ncbi request reprint HIV-1 immune suppression and antimalarial treatment outcome in Zambian adults with uncomplicated malaria
    Jean Pierre Van Geertruyden
    Department of Parasitology, Unit of Epidemiology, Institute of Tropical Medicine, Nationalestraat 155 B2000 Antwerp, Belgium
    J Infect Dis 194:917-25. 2006
    ..We assessed the influence that HIV-1 immune suppression has on the efficacy of antimalarial treatment in adults with uncomplicated malaria...
  62. doi request reprint Depression and posttraumatic stress disorder among HIV-infected Gambians on antiretroviral therapy
    Kevin Peterson
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    AIDS Patient Care STDS 26:589-96. 2012
    ..Integrating the CES-D10 or a similar instrument into patient preparation for ART is recommended in order to identify those who may benefit from further mental health investigations, specific therapy, or closer follow-up during early ART...
  63. pmc Return to normal life after AIDS as a reason for lost to follow-up in a community-based antiretroviral treatment program
    Stella T Alamo
    Medical Department, Reach Out Mbuya Parish HIV AIDS Initiative, Kampala, Uganda
    J Acquir Immune Defic Syndr 60:e36-45. 2012
    ..To understand reasons for lost-to-follow-up (LTFU) from a community-based antiretroviral therapy program in Uganda...
  64. pmc High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort
    Damalie Nakanjako
    Department of Medicine, Makerere University School of Medicine, Kampala, Uganda
    BMC Infect Dis 11:43. 2011
    ..The levels of T-cell immune activation and exhaustion after long-term, suppressive ART and their correlation with CD4 T-cell count reconstitution among ART-treated patients in African cohorts have not been extensively evaluated...
  65. ncbi request reprint Efficient stimulation of HIV-1-specific T cells using dendritic cells electroporated with mRNA encoding autologous HIV-1 Gag and Env proteins
    Ellen R A Van Gulck
    HIV and Retrovirology Research Unit, Department of Microbiology, Institute of Tropical Medicine of Antwerp, Nationalestraat 155, 2000 Antwerp, Belgium
    Blood 107:1818-27. 2006
    ..These findings open a major perspective for the development of patient-specific immunotherapy for HIV-1 disease...
  66. ncbi request reprint Bilateral pedal edema in an HIV patient: Lopinavir/Ritonavir-containing treatment regimen as a potential cause?
    Hasan M Shihab
    Infectious Diseases Institute, Makerere University, Kampala, Uganda
    J Infect Dev Ctries 3:405-7. 2009
    ..The lack of an alternate explanation led us to suspect that Lopinavir/Ritonavir was potentially responsible for the edema...
  67. doi request reprint Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
    William Worodria
    Department of Medicine, Makerere University College of Health Sciences, Mulago Hospital, Kampala, Uganda
    J Acquir Immune Defic Syndr 58:32-7. 2011
    ..Tuberculosis-HIV (TB-HIV) coinfection remains an important cause of mortality in antiretroviral therapy (ART) programs. In a cohort of TB-HIV-coinfected patients starting ART, we examined the incidence and predictors of early mortality...
  68. pmc Utilization of HIV and tuberculosis services by health care workers in Uganda: implications for occupational health policies and implementation
    Esther Buregyeya
    Makerere University School of Public Health, Kampala, Uganda
    PLoS ONE 7:e46069. 2012
    ..Challenges to and gaps in access to HIV services among HCWs may thus compromise TB infection control. This study assessed HCWs HIV and TB screening uptake and explored their preferences for provision of HIV and TB care...
  69. ncbi request reprint Autopsy acceptance rate and reasons for decline in Mulago Hospital, Kampala, Uganda
    Janneke A Cox
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    Trop Med Int Health 16:1015-8. 2011
    ..To determine the autopsy acceptance rate and reasons for decline at Mulago Hospital, Kampala, Uganda...
  70. ncbi request reprint Strategies to optimize HIV treatment outcomes in resource-limited settings
    Damalie Nakanjako
    Faculty of Medicine, Department of Internal Medicine, Makerere University, Kampala, Uganda
    AIDS Rev 11:179-89. 2009
    ....
  71. pmc Factors associated with carcinoma of the oesophagus at Mulago Hospital, Uganda
    Ponsiano Ocama
    Department of Medicine, Makerere University, Uganda
    Afr Health Sci 8:80-4. 2008
    ..Risk factors for this cancer have been identified but not studied systematically in Uganda. Identification of these factors would enable establishment of preventive measures...
  72. ncbi request reprint Review editorial: prevention of tuberculosis in resource-poor countries with increasing access to highly active antiretroviral treatment
    Ludwig Apers
    Institute of Tropical Medicine, Antwerp, Belgium
    Trop Med Int Health 10:1209-14. 2005
    ..We review various aspects of TB preventive treatment in countries with a high prevalence of HIV-TB co-infection and limited resources but with increasing access to ARV treatment...
  73. pmc Functional adrenal insufficiency among critically ill patients with human immunodeficiency virus in a resource-limited setting
    David B Meya
    Infectious Disease Institute, Makerere University, Faculty of Medicine, Kampala, Uganda
    Afr Health Sci 7:101-7. 2007
    ..Functional adrenal insufficiency (FAI) is associated with increased mortality and is defined as subnormal cortisol production during acute severe illness...
  74. pmc Implementation of tuberculosis infection control in health facilities in Mukono and Wakiso districts, Uganda
    Esther Buregyeya
    School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda
    BMC Infect Dis 13:360. 2013
    ..Understanding the reasons for low level of implementation is critical. The study aim was to assess TBIC practices and barriers to implementation in two districts in Uganda...
  75. ncbi request reprint The use of erection enhancing medication and party drugs among men living with HIV in Europe
    Iris De Ryck
    Institute of Tropical Medicine, HIV AIDS Center, Antwerp, Belgium
    AIDS Care 25:1062-6. 2013
    ..Medical provision of EEM should be combined with a discussion on safer sex behavior and the risk related to concomitant use of party drugs and illegal EEM. ..
  76. ncbi request reprint The added value of a CD4 count to identify patients eligible for highly active antiretroviral therapy among HIV-positive adults in Cambodia
    Lut Lynen
    Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium
    J Acquir Immune Defic Syndr 42:322-4. 2006
    ..Our data suggest that, in settings with limited access to CD4 count testing, it might be useful to target this test to patients in WHO stage 3 whose staging is based on weight loss alone, to avoid unnecessary treatment...
  77. ncbi request reprint Antiretroviral drug resistance profiles and response to second-line therapy among HIV type 1-infected Ugandan children
    Victor Musiime
    Joint Clinical Research Centre JCRC, Kampala, Uganda
    AIDS Res Hum Retroviruses 29:449-55. 2013
    ..Multiple RAMs were observed among HIV-1-infected children with virological failure on first-line ART with M184V and K103N most frequent. The children responded favorably to boosted PI-based second-line ART...
  78. ncbi request reprint Remote consultations and HIV/AIDS continuing education in low-resource settings
    Maria Zolfo
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    Int J Med Inform 75:633-7. 2006
    ..Telemedicine is a way to support physicians working in resource-poor settings, providing remote consultations and continuing medical education on HIV/AIDS care...
  79. pmc Retention in a NGO supported antiretroviral program in the Democratic Republic of Congo
    Olivier Koole
    Institute of Tropical Medicine, Antwerp, Belgium
    PLoS ONE 7:e40971. 2012
    ..Retention of patients in ART care is a major challenge in sub-Saharan programs. Retention is also one of the key indicators to evaluate the success of ART programs...
  80. pmc Electronic medical records and same day patient tracing improves clinic efficiency and adherence to appointments in a community based HIV/AIDS care program, in Uganda
    Stella T Alamo
    Medical Department, Reach Out Mbuya HIV AIDS Initiative, Kampala, Uganda
    AIDS Behav 16:368-74. 2012
    ..8% The total median waiting time to see providers significantly decreased from 291 to 94 min. Our findings suggest that EMR and same day patient tracing can significantly reduce missed appointments, and LTFU and improve clinic efficiency...
  81. doi request reprint Provider-initiated HIV testing for paediatric inpatients and their caretakers is feasible and acceptable
    Rhoda K Wanyenze
    Makerere University School of Public Health, Kampala, Uganda
    Trop Med Int Health 15:113-9. 2010
    ..We introduced HIV Counselling and Testing (HCT) for hospitalised children and their caretakers in Mulago teaching hospital in Uganda to assess its feasibility...
  82. ncbi request reprint When to switch for antiretroviral treatment failure in resource-limited settings?
    Marc Vekemans
    Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium
    AIDS 21:1205-6. 2007
  83. ncbi request reprint The role of raltegravir in the treatment of HIV-2 infections: evidence from a case series
    Kevin Peterson
    Department of Clinical Science, Institute of Tropical Medicine, Antwerp, Belgium
    Antivir Ther 17:1097-100. 2012
    ..Our series confirms the clinical effectiveness of raltegravir in HIV-2-infected patients when given with other antiretrovirals to which the virus is susceptible...
  84. pmc Decrease of vitamin D concentration in patients with HIV infection on a non nucleoside reverse transcriptase inhibitor-containing regimen
    Anali Conesa-Botella
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    AIDS Res Ther 7:40. 2010
    ..We compared 25-hydroxyvitamin D plasma [25-(OH)D] concentration in paired samples before and after 12 months of HAART. 25-(OH)D levels are presented using two different cut-offs: <20 ng/ml and <30 ng/ml...
  85. doi request reprint A randomized controlled trial to evaluate the effectiveness of a board game on patients' knowledge uptake of HIV and sexually transmitted diseases at the Infectious Diseases Institute, Kampala, Uganda
    Jane N Wanyama
    Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda
    J Acquir Immune Defic Syndr 59:253-8. 2012
    ..The object of this study was to assess the effect of this educational board game on the uptake of knowledge...
  86. pmc Socioeconomic support reduces nonretention in a comprehensive, community-based antiretroviral therapy program in Uganda
    Stella Talisuna-Alamo
    Medical Department, Reach Out Mbuya HIV AIDS Initiative, Kampala, Uganda
    J Acquir Immune Defic Syndr 59:e52-9. 2012
    ....
  87. pmc Challenges in developing national HIV guidelines: experience from the eastern Mediterranean
    Anja De Weggheleire
    Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat, Antwerp, Belgium
    Bull World Health Organ 89:442-50. 2011
    ....
  88. ncbi request reprint Management of Kaposi's sarcoma in resource-limited settings in the era of HAART
    Lut Lynen
    Clinical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium
    AIDS Rev 7:13-21. 2005
    ..In this paper we review current KS treatments available worldwide and discuss the implications of the increased access to antiretrovirals for KS treatment strategies in resource-limited settings...
  89. pmc Free antiretrovirals must not be restricted only to treatment-naive patients. Experience in Uganda suggests that restricting access is not the way forward
    Robert Colebunders
    Infectious Diseases Institute, Faculty of Medicine, Makerere University, Kampala, Uganda
    PLoS Med 2:e276. 2005
  90. ncbi request reprint The effect of highly active antiretroviral treatment on viral load and antiretroviral drug levels in breast milk
    Robert Colebunders
    Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
    AIDS 19:1912-5. 2005
    ..Compared with the plasma concentration, the breast milk concentration was between 68 and 90% for nevirapine, 6 and 24% for nelfinavir and 90 and 540% for indinavir...
  91. doi request reprint A telemedicine service for HIV/AIDS physicians working in developing countries
    Maria Zolfo
    Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium
    J Telemed Telecare 17:65-70. 2011
    ..Nonetheless, there was a declining trend in the rate of use of the service...
  92. ncbi request reprint Human and simian immunodeficiency virus-infected chimpanzees do not have increased intracellular levels of beta-chemokines in contrast to infected humans
    Pascale Ondoa
    Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium
    J Med Virol 69:297-305. 2003
    ..The data suggest that neither pre-nor post-exposure levels of intracellular beta-chemokines are correlated with the subsequent control of disease progression...
  93. ncbi request reprint Multiple tuberculous brain abscesses in an HIV-infected patient successfully treated with HAART and antituberculous treatment
    E Bottieau
    Dept of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, B 2000 Antwerp, Belgium
    Infection 31:118-20. 2003
    ..We describe an HIV-infected patient presenting with multiple TBA who recovered completely with a combination of HAART and anti-tuberculous treatment...
  94. pmc Nevirapine pharmacokinetics when initiated at 200 mg or 400 mg daily in HIV-1 and tuberculosis co-infected Ugandan adults on rifampicin
    Mohammed Lamorde
    Research Department, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda
    J Antimicrob Chemother 66:180-3. 2011
    ..rifampicin lowers nevirapine plasma concentrations by inducing cytochrome P450. However, few data are available on this interaction during the lead-in period of nevirapine treatment...
  95. ncbi request reprint Short communication: a cluster of Marburg virus disease involving an infant
    Matthias Borchert
    Epidemiology Unit, Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium
    Trop Med Int Health 7:902-6. 2002
    ..The findings show that mild cases of MHF have to be expected during an outbreak and point out the difficulty to base patient management decisions on clinical case definitions alone...
  96. ncbi request reprint Differences in perceptions on sexual and reproductive health between service providers and people living with HIV: a qualitative elicitation study
    Christiana Maria Nostlinger
    Prins Leopold Institute of Tropical Medicine, Clinical Sciences, Antwerp, Belgium
    Psychol Health Med 13:516-28. 2008
    ..SP need adequate counseling training to tackle SRH-related issues. A better integration between HIV care programs and SRH care settings is needed to improve effective service provision...
  97. pmc Development, evaluation, and validation of an oligonucleotide probe hybridization assay to subtype human immunodeficiency virus type 1 circulating recombinant form CRF02_AG
    Harr F Njai
    Department of Microbiology, Institute of Tropical Medicine, Antwerp
    J Clin Microbiol 42:1428-33. 2004
    ..Moreover, this technology can easily be applied in laboratories in developing countries...
  98. ncbi request reprint Co-trimoxazole prophylaxis in tropical countries in the era of highly active antiretroviral therapy: do we know enough?
    Lut Lynen
    Prince Leopold Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium
    Trans R Soc Trop Med Hyg 101:1059-60. 2007
    ..Together with the need for more research to identify optimal ART regimens for resource-poor settings, research regarding optimal chemoprophylaxis against opportunistic infections should also remain high on the agenda...
  99. doi request reprint Sexual protection behavior in HIV-positive gay men: testing a modified information-motivation-behavioral skills model
    Christiana Nöstlinger
    Department of Microbiology, Institute of Tropical Medicine, Nationalestraat 155, 2000, Antwerp, Belgium
    Arch Sex Behav 40:817-27. 2011
    ..Besides the original IMB constructs, HIV-specific variables, including sexual partners' serostatus and mental health, explained condom use. Such factors should be considered in clinical interventions to promote "positive prevention."..
  100. ncbi request reprint Imported Katayama fever: clinical and biological features at presentation and during treatment
    Emmanuel Bottieau
    Department of Clinical Sciences, Institute of Tropical Medicine IMTA, Nationalestraat 155, 2000 Antwerp, Belgium
    J Infect 52:339-45. 2006
    ..To investigate the characteristics of imported Katayama fever (acute schistosomiasis) as well as evolution and outcome under treatment...
  101. ncbi request reprint Five-year experience with scaling-up access to antiretroviral treatment in an HIV care programme in Cambodia
    Sopheak Thai
    Infectious Disease Department, Sihanouk Hospital Center of HOPE, Phnom Penh, Cambodia
    Trop Med Int Health 14:1048-58. 2009
    ..To evaluate a 5-year HIV care programme (2003-2007) in the Sihanouk Hospital Center of HOPE, Phnom Penh, Cambodia...