Yves E Henrotin

Summary

Country: Belgium

Publications

  1. doi request reprint [Guidelines for the management of knee and hip osteoarthritis: For whom? Why? To do what?]
    Yves Henrotin
    Universite de Liege, CHU Sart Tilman, Institut de Pathologie, unité de recherche sur l os et cartilage UROC, 5, 4000 Liege, Belgique
    Presse Med 39:1180-8. 2010
  2. doi request reprint Chondroitin and glucosamine in the management of osteoarthritis: an update
    Yves Henrotin
    Bone and Cartilage Research Unit, Institute of Pathology, Level 5, CHU Sart Tilman, University of Liege, 4000, Liege, Belgium
    Curr Rheumatol Rep 15:361. 2013
  3. pmc Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, Liege, 4000, Belgium
    BMC Res Notes 6:115. 2013
  4. doi request reprint Early decrease of serum biomarkers of type II collagen degradation (Coll2-1) and joint inflammation (Coll2-1 NO₂ ) by hyaluronic acid intra-articular injections in patients with knee osteoarthritis: a research study part of the Biovisco study
    Y Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    J Orthop Res 31:901-7. 2013
  5. doi request reprint Subchondral bone and osteoarthritis: biological and cellular aspects
    Y Henrotin
    Bone and Cartilage Research Unit, University of Liege, 4000, Liege, Belgium
    Osteoporos Int 23:S847-51. 2012
  6. pmc Intra-articular use of a medical device composed of hyaluronic acid and chondroitin sulfate (Structovial CS): effects on clinical, ultrasonographic and biological parameters
    Yves Henrotin
    Physical Therapy and Rehabilitation Department, Princess Paola Hospital, Vivalia, Marche en Famenne, Bone and Cartilage Research Unit, University of Liège Institute of Pathology, Level 5, CHU Sart Tilman, 4000, Liege, Belgium
    BMC Res Notes 5:407. 2012
  7. pmc Characterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate
    Cecile Lambert
    Bone and Cartilage Research Unit, Institute of Pathology, CHU Sart Tilman, 4000 Liege, Belgium
    Arthritis Res Ther 14:R58. 2012
  8. pmc Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    Arthritis Res Ther 14:201. 2012
  9. doi request reprint Fibulin 3 peptides Fib3-1 and Fib3-2 are potential biomarkers of osteoarthritis
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Liege, Belgium
    Arthritis Rheum 64:2260-7. 2012
  10. doi request reprint Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives
    Y Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    Osteoarthritis Cartilage 20:215-7. 2012

Collaborators

Detail Information

Publications44

  1. doi request reprint [Guidelines for the management of knee and hip osteoarthritis: For whom? Why? To do what?]
    Yves Henrotin
    Universite de Liege, CHU Sart Tilman, Institut de Pathologie, unité de recherche sur l os et cartilage UROC, 5, 4000 Liege, Belgique
    Presse Med 39:1180-8. 2010
    ..The barriers for the guidelines implementation are the lack of interest of the practitioners, the lack of scientific advances in the OA diagnosis and treatments and the low applicability of these guidelines in the daily practice...
  2. doi request reprint Chondroitin and glucosamine in the management of osteoarthritis: an update
    Yves Henrotin
    Bone and Cartilage Research Unit, Institute of Pathology, Level 5, CHU Sart Tilman, University of Liege, 4000, Liege, Belgium
    Curr Rheumatol Rep 15:361. 2013
    ..This review will discuss all these subjects and emphasize the importance of the quality of tested compounds for achieving high quality clinical trials. ..
  3. pmc Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, Liege, 4000, Belgium
    BMC Res Notes 6:115. 2013
    ..This paper summarizes the available evidence for beneficial effects of GlcN on joint health and proposes new insight into the design of future clinical trials aimed at identifying beneficial physiological effect of GlcN on joint tissues...
  4. doi request reprint Early decrease of serum biomarkers of type II collagen degradation (Coll2-1) and joint inflammation (Coll2-1 NO₂ ) by hyaluronic acid intra-articular injections in patients with knee osteoarthritis: a research study part of the Biovisco study
    Y Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    J Orthop Res 31:901-7. 2013
    ..The serum level of Coll2-1 appeared to be a predictive factor for response to treatment...
  5. doi request reprint Subchondral bone and osteoarthritis: biological and cellular aspects
    Y Henrotin
    Bone and Cartilage Research Unit, University of Liege, 4000, Liege, Belgium
    Osteoporos Int 23:S847-51. 2012
    ..This narrative review describes these physiopathological mechanisms and identifies possible therapeutic targets for pharmacological modalities...
  6. pmc Intra-articular use of a medical device composed of hyaluronic acid and chondroitin sulfate (Structovial CS): effects on clinical, ultrasonographic and biological parameters
    Yves Henrotin
    Physical Therapy and Rehabilitation Department, Princess Paola Hospital, Vivalia, Marche en Famenne, Bone and Cartilage Research Unit, University of Liège Institute of Pathology, Level 5, CHU Sart Tilman, 4000, Liege, Belgium
    BMC Res Notes 5:407. 2012
    ....
  7. pmc Characterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate
    Cecile Lambert
    Bone and Cartilage Research Unit, Institute of Pathology, CHU Sart Tilman, 4000 Liege, Belgium
    Arthritis Res Ther 14:R58. 2012
    ..The effects of interleukin (IL)-1β and chondroitin sulfate (CS) on the expression of pro- and anti-angiogenic factors by synovial fibroblasts cells (SFC) were also studied...
  8. pmc Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    Arthritis Res Ther 14:201. 2012
    ..Finally, the importance of study design and criteria of evaluation are highlighted as new compounds represent new interesting options for the management of OA...
  9. doi request reprint Fibulin 3 peptides Fib3-1 and Fib3-2 are potential biomarkers of osteoarthritis
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Liege, Belgium
    Arthritis Rheum 64:2260-7. 2012
    ..This study was undertaken to identify new biomarkers of osteoarthritis (OA) by proteomics analysis and to develop specific immunoassays to detect and quantify them...
  10. doi request reprint Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives
    Y Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    Osteoarthritis Cartilage 20:215-7. 2012
    ....
  11. pmc Development and validation of a questionnaire assessing volitional competencies to enhance the performance of physical activities in chronic low back pain patients
    Céline Mathy
    Social Psychology Unit, Universite Libre de Bruxelles, Brussels, Belgium
    BMC Musculoskelet Disord 12:111. 2011
    ..However, there is at present no questionnaire allowing assessing the capacity of implementation intentions of physical activities in LBP patients...
  12. pmc Muscle: a source of progenitor cells for bone fracture healing
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, CHU Sart Tilman, 4000 Liege, Belgium
    BMC Med 9:136. 2011
    ..Please see related article: http://www.biomedcentral.com/1471-2474/12/288...
  13. pmc Study of the information delivery by general practitioners and rheumatologists to patients with acute low back pain
    Yves Henrotin
    Belgian Back Society, Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, CHU Sart Tilman, 4000, Liege, Belgium
    Eur Spine J 20:720-30. 2011
    ..This suggests that GP information campaign can modify the message that they deliver to LBP, and subsequently could change patient's beliefs on LBP...
  14. doi request reprint Nutraceuticals: do they represent a new era in the management of osteoarthritis? - a narrative review from the lessons taken with five products
    Y Henrotin
    Bone and Cartilage Research Unit, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    Osteoarthritis Cartilage 19:1-21. 2011
    ..Evidences that can support health, physiological or functional benefit on osteoarthritis (OA) were gathered and the level of evidence relative to each of these ingredients was highlighted...
  15. ncbi request reprint Biochemical biomarkers of oxidative collagen damage
    Y Henrotin
    Institute of Pathology, University of Liege, CHU Sart Tilman, 4000 Liege, Belgium
    Adv Clin Chem 49:31-55. 2009
    ..This chapter reviews the structural and biochemical changes to collagen induced by reactive oxygen and nitrogen species and discusses recent data on the use of collagen-derived biomarkers for measuring oxidative damage...
  16. doi request reprint Biological actions of curcumin on articular chondrocytes
    Y Henrotin
    University of Liege, Institute of Pathology, Sart Tilman, Liege, Belgium
    Osteoarthritis Cartilage 18:141-9. 2010
    ....
  17. ncbi request reprint The role of reactive oxygen species in homeostasis and degradation of cartilage
    Y E Henrotin
    Bone and Cartilage Research Unit, Institute of Pathology, Level 5, CHU Sart Tilman, Liege, Belgium
    Osteoarthritis Cartilage 11:747-55. 2003
    ..ROS production has been found to increase in joint diseases, such as osteoarthritis and rheumatoid arthritis, but their role in joint diseases initiation and progression remains questionable...
  18. ncbi request reprint Type II collagen markers in osteoarthritis: what do they indicate?
    Yves Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, Liege, Belgium
    Curr Opin Rheumatol 19:444-50. 2007
    ..Based on this analysis, we propose an update to the classification of the type II collagen biomarkers...
  19. ncbi request reprint Antioxidant to treat osteoarthritis: dream or reality?
    Y Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    Curr Drug Targets 8:347-57. 2007
    ..However, until now, there is no consistent evidence that additional antioxidant supply is efficient to relieve OA symptoms or to prevent structural changes in OA cartilage...
  20. ncbi request reprint Avocado/soybean unsaponifiables prevent the inhibitory effect of osteoarthritic subchondral osteoblasts on aggrecan and type II collagen synthesis by chondrocytes
    Yves E Henrotin
    Bone and Cartilage Metabolism Research Unit, Institute of Pathology B23, Liege, Belgium
    J Rheumatol 33:1668-78. 2006
    ..To determine the effects of avocado/soybean unsaponifiables (ASU) on osteoblast-induced dysregulation of chondrocyte metabolism...
  21. ncbi request reprint Type II collagen peptides for measuring cartilage degradation
    Y Henrotin
    Bone and Cartilage Research Unit, Institute of Pathology, CHU Sart Tilman, 4000 Liege, Belgium
    Biorheology 41:543-7. 2004
    ..In conclusion, these preliminary results indicate that Coll 2-1 could be a predictive marker of knee OA progression...
  22. ncbi request reprint Avocado/soybean unsaponifiables increase aggrecan synthesis and reduce catabolic and proinflammatory mediator production by human osteoarthritic chondrocytes
    Yves E Henrotin
    Bone and Cartilage Metabolism Research Unit, University Hospital, CHU Sart Tilman, Liege, Belgium
    J Rheumatol 30:1825-34. 2003
    ..To investigate the effects of avocado (A)/soybean (S) unsaponifiables on the metabolism of human osteoarthritic (OA) chondrocytes cultured in alginate beads over 12 days...
  23. ncbi request reprint Oxygen and reactive oxygen species in cartilage degradation: friends or foes?
    Y Henrotin
    Bone and Cartilage Research Unit, University of Liege, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    Osteoarthritis Cartilage 13:643-54. 2005
    ..This review is focused on the influence of oxygen and derived reactive species on chondrocytes aging, metabolic function and chondrogenic phenotype...
  24. ncbi request reprint Pharmaceutical and nutraceutical management of canine osteoarthritis: present and future perspectives
    Yves Henrotin
    Bone and Cartilage Research Unit, Institute of Pathology, Level 5, CHU Sart Tilman, 4000 Liege, Belgium
    Vet J 170:113-23. 2005
    ..This paper provides an overview of recent discoveries in the pathophysiology and in the therapeutic management of osteoarthritis in dogs...
  25. ncbi request reprint In vitro effects of aceclofenac and its metabolites on the production by chondrocytes of inflammatory mediators
    Y Henrotin
    Bone and Cartilage Metabolism Research Unit, Institute of Pathology, CHU Sart Tilman, Liege, Belgium
    Inflamm Res 50:391-9. 2001
    ....
  26. doi request reprint Subchondral bone in osteoarthritis physiopathology: state-of-the art and perspectives
    Y Henrotin
    Bone and Cartilage Research Unit, Institute of Pathology, CHU Sart Tilman, University of Liege, Liege, Belgium
    Biomed Mater Eng 19:311-6. 2009
    ..In this paper, we propose a short review of the recent advances in the understanding of the role played by subchondral bone in OA...
  27. ncbi request reprint Effects of rhein on human articular chondrocytes in alginate beads
    Christelle Sanchez
    Bone and Cartilage Metabolism Research Unit, Institute of Pathology, CHU Sart Tilman, 4000 Liege, Belgium
    Biochem Pharmacol 65:377-88. 2003
    ..The COX-2 and iNOS mRNA levels and IL-8 production were not modified by rhein.Overall, these results contribute to explain the clinical efficiency of rhein and give new information on its mechanisms of action...
  28. ncbi request reprint Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs
    Christelle Sanchez
    Bone and Cartilage Metabolism Research Unit, University Hospital, CHU Sart Tilman, Liege, Belgium
    J Rheumatol 29:772-82. 2002
    ....
  29. doi request reprint Phenotypic characterization of osteoblasts from the sclerotic zones of osteoarthritic subchondral bone
    Christelle Sanchez
    University of Liege, Sart Tilman, Liege, Belgium
    Arthritis Rheum 58:442-55. 2008
    ..To determine the phenotype of osteoblasts from the sclerotic zones of human osteoarthritic (OA) subchondral bone...
  30. ncbi request reprint Biochemical markers of bone and cartilage remodeling in prediction of longterm progression of knee osteoarthritis
    Olivier Bruyere
    WHO Collaborating Center for Public Health Aspect of Osteoarticular Disorders CCPHAOD, Liege, Belgium
    J Rheumatol 30:1043-50. 2003
    ..To investigate the relationship between biochemical markers of bone and cartilage remodeling and severity or progression (symptoms and structure) of knee osteoarthritis (OA)...
  31. ncbi request reprint Differential regulation of chondrocyte metabolism by oncostatin M and interleukin-6
    Christelle Sanchez
    Bone and Cartilage Metabolism Research Unit, Institute of Pathology B23, University Hospital, Sart Tilman, 4000 Liege, Belgium
    Osteoarthritis Cartilage 12:801-10. 2004
    ..To determine the effects of interleukin (IL)-6 and oncostatin M (OSM) added separately or in combination with IL-1beta on human osteoarthritic (OA) chondrocytes in alginate beads...
  32. ncbi request reprint Impact of the joint space width measurement method on the design of knee osteoarthritis studies
    Olivier Bruyere
    WHO Collaborating Center for Public Health Aspects of Osteoarticular Disorders, Liege, Belgium
    Aging Clin Exp Res 15:136-41. 2003
    ..The aim of this study was to assess the impact of the joint space width measurement method on sample size calculation in knee OA studies...
  33. ncbi request reprint Radiologic features poorly predict clinical outcomes in knee osteoarthritis
    Olivier Bruyere
    WHO Collaborating Center for Public Health Aspect of Osteoarticular Disorders, Liege, Belgium
    Scand J Rheumatol 31:13-6. 2002
    ..To assess the impact of radiographic severity and progression on pain and disability...
  34. doi request reprint Regulation of subchondral bone osteoblast metabolism by cyclic compression
    Christelle Sanchez
    University of Liege, Liege, Belgium
    Arthritis Rheum 64:1193-203. 2012
    ..This study was undertaken to evaluate the effects of cyclic compression on osteoblasts from OA subchondral bone...
  35. ncbi request reprint Naturocetic (glucosamine and chondroitin sulfate) compounds as structure-modifying drugs in the treatment of osteoarthritis
    Jean Yves Reginster
    Bone and Cartilage Metabolism Research Unit, University of Liege, Belgium
    Curr Opin Rheumatol 15:651-5. 2003
    ..Several entities have been investigated carefully for the symptomatic and structural management of osteoarthritis. This review reports recent findings suggesting that such compounds may delay the structural progression of osteoarthritis...
  36. doi request reprint High expression of PGE2 enzymatic pathways in cervical (pre)neoplastic lesions and functional consequences for antigen-presenting cells
    Michael Herfs
    Department of Pathology B23, GIGA Cancer, University of Liege, CHU Sart Tilman, 4000, Liege, Belgium
    Cancer Immunol Immunother 58:603-14. 2009
    ....
  37. doi request reprint Relationship between biochemical markers and radiographic scores in the evaluation of the osteoarticular status of Warmblood stallions
    Denis Verwilghen
    Department of Clinical Sciences, Equine Clinic, Faculty of Veterinary Medicine of Liege, B 4000 Liege, Belgium
    Res Vet Sci 87:319-28. 2009
    ..A high percentage of horses with distal interphalangeal joint effusion was present in this study and was associated with decreased IGF-I and increased Coll2-1 levels...
  38. ncbi request reprint Current concepts in the therapeutic management of osteoarthritis with glucosamine
    Jean Yves Reginster
    WHO Collaborating Center for Public Health Aspects of Rheumatic Diseases, Liege, Belgium
    Bull Hosp Jt Dis 63:31-6. 2005
    ....
  39. ncbi request reprint New perspectives in the management of osteoarthritis. structure modification: facts or fantasy?
    Jean Yves Reginster
    Bone and Cartilage Metabolism Research Unit, University of Liege, CHU Centre Ville, Policliniques L Brull, Liege, Belgium
    J Rheumatol Suppl 67:14-20. 2003
    ..An important issue is that all conclusive studies with such chemical entities resulted from the use of prescription medicines and not over-the-counter or nutriceutical supplements...
  40. ncbi request reprint Effects of glucocorticoids on the respiratory burst of Chlamydia-primed THP-1 cells
    Ange Mouithys-Mickalad
    Centre for Oxygen, Research and Development CORD, Institut de Chimie, B6a, University of Liege, Sart Tilman, 4000 Liege, Belgium
    Biochem Biophys Res Commun 318:941-8. 2004
    ..On the expression of p22(phox), a protein subunit of the NADPH oxidase, HCT had an increasing and MPL a decreasing effect. Glucocorticoids thus had unexpected effects on the inflammatory response of Chlamydia-primed monocytes...
  41. ncbi request reprint New serum biochemical markers (Coll 2-1 and Coll 2-1 NO2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis and rheumatoid arthritis
    Michelle Deberg
    Bone and Cartilage Research Unit, University of Liege, Sart Tilman, 4000 Liege, Belgium
    Osteoarthritis Cartilage 13:258-65. 2005
    ..We have developed immunoassays specific for a peptide of the alpha-helical region of type II collagen 108HRGYPGLDG116 (Coll 2-1) and its nitrated form 108HRGY(NO2)PGLDG116 (Coll 2-1 NO2) in biological fluids...
  42. doi request reprint The L1 major capsid protein of HPV16 differentially modulates APC trafficking according to the vaccination or natural infection context
    Ludivine Herman
    Department of Experimental Pathology, University Hospital of Liege, CHU Sart Tilman, Liege, Belgium
    Eur J Immunol 40:3075-84. 2010
    ..Taken together, our data demonstrate that HPV16 VLP may differentially regulate the immune protective response according to their target cells...
  43. ncbi request reprint Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis
    Florent Richy
    Faculty of Medicine, Department of Public Health, Public Health and Epidemiology, University of Liege, Liege, Belgium
    Arch Intern Med 163:1514-22. 2003
    ....
  44. ncbi request reprint Runx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expression
    Virginie Lamour
    Metastasis Research Laboratory, Center of Experimental Cancer Research and Bone and Cartilage Metabolism Research Unit, University of Liege, 4000 Liege, Belgium
    J Biol Chem 282:36240-9. 2007
    ....