Tim S Nawrot

Summary

Affiliation: Hasselt University
Country: Belgium

Publications

  1. doi request reprint Public health importance of triggers of myocardial infarction: a comparative risk assessment
    Tim S Nawrot
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    Lancet 377:732-40. 2011
  2. pmc Decreased mitochondrial DNA content in association with exposure to polycyclic aromatic hydrocarbons in house dust during wintertime: from a population enquiry to cell culture
    Nicky Pieters
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    PLoS ONE 8:e63208. 2013
  3. pmc An epidemiological appraisal of the association between heart rate variability and particulate air pollution: a meta-analysis
    Nicky Pieters
    Hasselt University, Agoralaan Gebouw D, Diepenbeek, Belgium
    Heart 98:1127-35. 2012
  4. pmc Host and environmental predictors of exhaled breath temperature in the elderly
    Esmée Bijnens
    Centre for Environmental Sciences, Hasselt University, Agoralaan Building D, Diepenbeek 3590, Belgium
    BMC Public Health 13:1226. 2013
  5. pmc Blood pressure and particulate air pollution in schoolchildren of Lahore, Pakistan
    Muhammad Sughis
    Department of Public Health, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Public Health 12:378. 2012
  6. pmc Subclinical responses in healthy cyclists briefly exposed to traffic-related air pollution: an intervention study
    Lotte Jacobs
    Occupational and Environmental Medicine, Unit of Lung Toxicology, KULeuven, Herestraat 49, 3000 Leuven, Belgium
    Environ Health 9:64. 2010
  7. pmc Medical conditions of nursing home admissions
    Gilberte Van Rensbergen
    Department of Public Health, KULeuven, Leuven, Belgium
    BMC Geriatr 10:46. 2010
  8. doi request reprint Cadmium exposure in the population: from health risks to strategies of prevention
    Tim S Nawrot
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    Biometals 23:769-82. 2010
  9. doi request reprint Bronchoalveolar lavage neutrophilia in acute lung allograft rejection and lymphocytic bronchiolitis
    Robin Vos
    Laboratory of Pneumology, Katholieke Universiteit Leuven and University Hospital Gasthuisberg, 49 Herestraat, Leuven, Belgium
    J Heart Lung Transplant 29:1259-69. 2010
  10. ncbi request reprint Blood pressure and blood selenium: a cross-sectional and longitudinal population study
    Tim S Nawrot
    Studies Coordinating Centre, Laboratory of Hypertension, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, Campus Gasthuisberg, University of Leuven, Leuven, Belgium
    Eur Heart J 28:628-33. 2007

Collaborators

Detail Information

Publications35

  1. doi request reprint Public health importance of triggers of myocardial infarction: a comparative risk assessment
    Tim S Nawrot
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    Lancet 377:732-40. 2011
    ..However, the importance and relevance of each trigger are uncertain. We compared triggers of myocardial infarction at an individual and population level...
  2. pmc Decreased mitochondrial DNA content in association with exposure to polycyclic aromatic hydrocarbons in house dust during wintertime: from a population enquiry to cell culture
    Nicky Pieters
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    PLoS ONE 8:e63208. 2013
    ..The ability of benzo(a)pyrene (range 0 µM to 500 µM) to lower mtDNA content was confirmed in vitro in human TK6 cells. Based on these findings, mtDNA content can be a target of PAH toxicity in humans...
  3. pmc An epidemiological appraisal of the association between heart rate variability and particulate air pollution: a meta-analysis
    Nicky Pieters
    Hasselt University, Agoralaan Gebouw D, Diepenbeek, Belgium
    Heart 98:1127-35. 2012
    ..The authors performed a meta-analysis to determine how consistent this association is...
  4. pmc Host and environmental predictors of exhaled breath temperature in the elderly
    Esmée Bijnens
    Centre for Environmental Sciences, Hasselt University, Agoralaan Building D, Diepenbeek 3590, Belgium
    BMC Public Health 13:1226. 2013
    ..The putative mechanism of this approach is based upon changes in the blood flow. So far potential factors that influence breath temperature have not been studied in the general population...
  5. pmc Blood pressure and particulate air pollution in schoolchildren of Lahore, Pakistan
    Muhammad Sughis
    Department of Public Health, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Public Health 12:378. 2012
    ..Air pollution is a growing health problem for urban populations in emerging economies. The present study examines the (cross-sectional) relation between blood pressure and particulate air pollution in schoolchildren of Lahore (Pakistan)...
  6. pmc Subclinical responses in healthy cyclists briefly exposed to traffic-related air pollution: an intervention study
    Lotte Jacobs
    Occupational and Environmental Medicine, Unit of Lung Toxicology, KULeuven, Herestraat 49, 3000 Leuven, Belgium
    Environ Health 9:64. 2010
    ..To address this conundrum we investigated if a bicycle journey along a busy commuting road would induce changes in biomarkers of pulmonary and systematic inflammation in a group of healthy subjects...
  7. pmc Medical conditions of nursing home admissions
    Gilberte Van Rensbergen
    Department of Public Health, KULeuven, Leuven, Belgium
    BMC Geriatr 10:46. 2010
    ..We investigated the medical reason (primary diagnosis) of a nursing home admission with respect to the underlying disease...
  8. doi request reprint Cadmium exposure in the population: from health risks to strategies of prevention
    Tim S Nawrot
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    Biometals 23:769-82. 2010
    ....
  9. doi request reprint Bronchoalveolar lavage neutrophilia in acute lung allograft rejection and lymphocytic bronchiolitis
    Robin Vos
    Laboratory of Pneumology, Katholieke Universiteit Leuven and University Hospital Gasthuisberg, 49 Herestraat, Leuven, Belgium
    J Heart Lung Transplant 29:1259-69. 2010
    ..We hypothesized that bronchoalveolar lavage (BAL) neutrophilia may be increased in either acute rejection or lymphocytic bronchiolitis or may increase with increasing histologic severity...
  10. ncbi request reprint Blood pressure and blood selenium: a cross-sectional and longitudinal population study
    Tim S Nawrot
    Studies Coordinating Centre, Laboratory of Hypertension, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, Campus Gasthuisberg, University of Leuven, Leuven, Belgium
    Eur Heart J 28:628-33. 2007
    ..Western Europeans have low blood levels of selenium (BSe), an antioxidant trace element. In a Flemish population, we investigated the cross-sectional and longitudinal association of blood pressure (BP) with BSe...
  11. pmc Placental mitochondrial DNA content and particulate air pollution during in utero life
    Bram G Janssen
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    Environ Health Perspect 120:1346-52. 2012
    ..Studies emphasize the importance of particulate matter (PM) in the formation of reactive oxygen species and inflammation. We hypothesized that these processes can influence mitochondrial function of the placenta and fetus...
  12. ncbi request reprint Prevalence of hypertension, hypercholesterolemia, smoking and overweight in older Belgian adolescents
    Tim S Nawrot
    Studiecoördinatiecentrum, Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement Moleculair en Cardiovasculair Onderzoek, Katholieke Universiteit Leuven, Faculteit Geneeskunde, Leuven, Belgium
    Eur J Public Health 14:361-5. 2004
    ..The purpose of this study was to describe the prevalence of hypertension and other established CV risk factors in older adolescents...
  13. pmc Traffic air pollution and oxidized LDL
    Lotte Jacobs
    Occupational and Environmental Medicine, Unit of Lung Toxicology, Katholieke Universiteit Leuven, Leuven, Belgium
    PLoS ONE 6:e16200. 2011
    ..We tested this hypothesis in patients with diabetes, who are at high risk for atherosclerosis...
  14. pmc Bone resorption and environmental exposure to cadmium in women: a population study
    Rudolph Schutte
    Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Leuven, Belgium
    Environ Health Perspect 116:777-83. 2008
    ..Environmental exposure to cadmium decreases bone density indirectly through hypercalciuria resulting from renal tubular dysfunction...
  15. pmc Bone resorption and environmental exposure to cadmium in children: a cross--sectional study
    Muhammad Sughis
    Department of Public Health, Occupational and Environmental Medicine, Unit of Lung Toxicology, Katholieke Universiteit Leuven, Leuven, Belgium
    Environ Health 10:104. 2011
    ..In the present study we investigate the association between markers of bone demineralization [urinary calcium (Ca) and deoxypyridinoline (DPD) excretion] and urinary cadmium (Cd) excretion (as an index of lifetime body burden)...
  16. pmc Air pollution related prothrombotic changes in persons with diabetes
    Lotte Jacobs
    Occupational and Environmental Medicine, Unit of Lung Toxicology, Katholique Universiteit Leuven, Leuven, Belgium
    Environ Health Perspect 118:191-6. 2010
    ..However, the biological mechanisms of a possible prothrombotic effect underlying this enhanced susceptibility remain largely unknown...
  17. pmc The association between urinary kidney injury molecule 1 and urinary cadmium in elderly during long-term, low-dose cadmium exposure: a pilot study
    Valérie Pennemans
    Biomedical Research Institute, Hasselt University and Transnational University Limburg, School of Life Sciences, Diepenbeek, Belgium
    Environ Health 10:77. 2011
    ..However, so far the association between urinary cadmium and kidney injury molecule 1 in humans after long-term, low-dose cadmium exposure has not been studied...
  18. pmc Does air pollution trigger infant mortality in Western Europe? A case-crossover study
    Hans Scheers
    Department of Public Health, Occupational and Environmental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    Environ Health Perspect 119:1017-22. 2011
    ..Numerous studies show associations between fine particulate air pollutants [particulate matter with an aerodynamic diameter ≤ 10 μm (PM₁₀)] and mortality in adults...
  19. pmc Cadmium-related mortality and long-term secular trends in the cadmium body burden of an environmentally exposed population
    Tim S Nawrot
    Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Herestraat 49, Leuven, Belgium
    Environ Health Perspect 116:1620-8. 2008
    ..Few population studies have reported on the long-term changes in the internal cadmium dose and simultaneously occurring mortality...
  20. doi request reprint Long-term azithromycin therapy for bronchiolitis obliterans syndrome: divide and conquer?
    Robin Vos
    Laboratory of Pneumology, Katholieke Universiteit Leuven and University Hospital Gasthuisberg, Leuven, Belgium
    J Heart Lung Transplant 29:1358-68. 2010
    ..Azithromycin may reverse or halt the decline of pulmonary function (FEV(1)) in bronchiolitis obliterans syndrome (BOS). In this study we investigated the effects of long-term azithromycin treatment in lung transplant recipients with BOS...
  21. ncbi request reprint Telomere length and its associations with oxidized-LDL, carotid artery distensibility and smoking
    Tim S Nawrot
    Department of Molecular and Cardiovascular Research, Laboratory of Hypertension, University of Leuven, Study Coordinating Centre, Leuven, Belgium
    Front Biosci (Elite Ed) 2:1164-8. 2010
    ..03) than in non-smokers. Higher level of oxidized-LDL, is associated with shorter WBC telomeres and increased stiffness of the carotid artery. Smoking is marked by increased oxidative stress in concert with shortened WBC telomere length...
  22. pmc Impact of a stepwise introduction of smoke-free legislation on the rate of preterm births: analysis of routinely collected birth data
    Bianca Cox
    Centre for Environmental Sciences, Hasselt University, Agoralaan Gebouw D, 3590 Diepenbeek, Belgium
    BMJ 346:f441. 2013
    ....
  23. ncbi request reprint Endothelial function and outdoor temperature
    Tim S Nawrot
    Study Coordinating Centre, Laboratory of Hypertension, Department of Molecular and Cardiovascular Research, University of Leuven, Leuven, Belgium
    Eur J Epidemiol 20:407-10. 2005
    ..Our findings suggest that endothelial dysfunction might contribute to the increase in cardiovascular morbidity and mortality associated with hot weather...
  24. ncbi request reprint Serum levels of club cell secretory protein (Clara) and short- and long-term exposure to particulate air pollution in adolescents
    Eline B Provost
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium Environmental Risk and Health, Flemish Institute for Technological Research VITO, Mol, Belgium
    Environ Int 68:66-70. 2014
    ..Studies in populations have shown that particulate air pollution is associated with changes in lung function in adolescents...
  25. pmc Neurobehavioral function and low-level exposure to brominated flame retardants in adolescents: a cross-sectional study
    Michał Kiciński
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    Environ Health 11:86. 2012
    ..Although the first reports of detrimental neurobehavioral effects in rodents appeared more than ten years ago, human data are sparse...
  26. doi request reprint Update in occupational and environmental respiratory disease 2007
    Tim S Nawrot
    Laboratory of Pneumology, K U Leuven, Laboratorium voor Pneumologie Longtoxicologie, Herestraat 49, B 3000 Leuven, Belgium
    Am J Respir Crit Care Med 177:696-700. 2008
  27. pmc Host and environmental determinants of polychlorinated aromatic hydrocarbons in serum of adolescents
    Tim S Nawrot
    Studiecoördinatiecentrum, Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement Moleculair en Cardiovasculair Onderzoek, Katholieke Universiteit Leuven, Faculteit Geneeskunde, Leuven, Belgium
    Environ Health Perspect 110:583-9. 2002
    ....
  28. ncbi request reprint Broncho-alveolar lavage fluid recovery correlates with airway neutrophilia in lung transplant patients
    Bart M Vanaudenaerde
    Laboratorium of Pneumology, Katholieke Universiteit Leuven, and Lung Transplantation Unit, University Hospital Gasthuisberg, Leuven, Belgium
    Respir Med 102:339-47. 2008
    ..Airway colonization in stable patients had no effect on airway inflammatory parameters, BFR and FEV1...
  29. pmc Where do the elderly die? The impact of nursing home utilisation on the place of death. Observations from a mortality cohort study in Flanders
    Gilberte Van Rensbergen
    Department of Public Health, Katholieke Universiteit Leuven, Leuven, Belgium
    BMC Public Health 6:178. 2006
    ..Studies showed the influence of gender, age, social-economical status and living arrangements on the place of death, but a facet not taken into account so far is the influence of the availability of nursing homes...
  30. pmc An epidemiological reappraisal of the familial aggregation of prostate cancer: a meta-analysis
    Michał Kiciński
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    PLoS ONE 6:e27130. 2011
    ..Our combined estimates show strong familial clustering and a significant effect-modification by age meaning that familial aggregation was associated with earlier disease onset (before age 65)...
  31. pmc Respiratory function and bronchial responsiveness among industrial workers exposed to different classes of occupational agents: a study from Algeria
    Farid Ould-Kadi
    Occupational and Environmental Medicine, School of Public Health, KULeuven, Leuven, Belgium
    J Occup Med Toxicol 2:11. 2007
    ..These results point to the necessity of preventive measures in solvent workers to avoid these adverse respiratory effects...
  32. ncbi request reprint The impact of traffic air pollution on bronchiolitis obliterans syndrome and mortality after lung transplantation
    Tim S Nawrot
    Centre for Environmental Sciences, Hasselt University, Diepenbeek, Belgium
    Thorax 66:748-54. 2011
    ..The authors assessed the association between proximity of the home to major roads and BOS and mortality in a cohort of patients after lung transplantation...
  33. ncbi request reprint Update in environmental and occupational medicine 2006
    Tim S Nawrot
    School of Public Health, Occupational and Environmental Medicine, Unit of Lung Toxicology, KU Leuven, Leuven, Belgium
    Am J Respir Crit Care Med 175:758-62. 2007
  34. ncbi request reprint How long do the systemic and ventilatory responses to toluene diisocyanate persist in dermally sensitized mice?
    Jeroen A J Vanoirbeek
    Laboratory of Lung Toxicology, Katholieke Universiteit Leuven, Leuven, Belgium
    J Allergy Clin Immunol 121:456-463.e5. 2008
    ..Years after removal from exposure, workers with occupational asthma still show respiratory symptoms and airway hyperresponsiveness on re-exposure to the offending agent...
  35. ncbi request reprint Blood pressure, serum total cholesterol and contraceptive pill use in 17-year-old girls
    Tim S Nawrot
    Studiecoördinatiecentrum, Hypertensie en Cardiovasculaire Revalidatie Eenheid, Departement Moleculair en Cardiovasculair Onderzoek, Katholieke Universiteit Leuven, Leuven, Belgium
    Eur J Cardiovasc Prev Rehabil 10:438-42. 2003
    ..Many studies have analysed the relation between cardiovascular risk factors and oral contraceptive use in adult women, whereas information on the possible health effects of oral contraceptive use during adolescence is lacking...