Niel Hens

Summary

Affiliation: Hasselt University
Country: Belgium

Publications

  1. ncbi Robust reconstruction and analysis of outbreak data: influenza A(H1N1)v transmission in a school-based population
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Belgium
    Am J Epidemiol 176:196-203. 2012
  2. ncbi Age-disparity, sexual connectedness and HIV infection in disadvantaged communities around Cape Town, South Africa: a study protocol
    Wim Delva
    South African Centre for Epidemiological Modelling and Analysis, Stellenbosch University, 19 Jonkershoek Road, Stellenbosch 7600, South Africa
    BMC Public Health 11:616. 2011
  3. ncbi Dynamics of HPV vaccination initiation in Flanders (Belgium) 2007-2009: a Cox regression model
    Eva Lefevere
    Herman Deleeck Centre for Social Policy, Antwerp University, St Jacobstraat 2, 2000 Antwerpen, Belgium
    BMC Public Health 11:470. 2011
  4. ncbi Estimating the impact of school closure on social mixing behaviour and the transmission of close contact infections in eight European countries
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Agoralaan 1, B3590 Diepenbeek, Belgium
    BMC Infect Dis 9:187. 2009
  5. ncbi Seventy-five years of estimating the force of infection from current status data
    N Hens
    Interuniversity Institute of Biostatistics and Statistical Bioinformatics, Hasselt University, B 3590 Diepenbeek, Belgium
    Epidemiol Infect 138:802-12. 2010
  6. ncbi The correlated and shared gamma frailty model for bivariate current status data: an illustration for cross-sectional serological data
    N Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Limburg, Belgium
    Stat Med 28:2785-800. 2009
  7. ncbi Mining social mixing patterns for infectious disease models based on a two-day population survey in Belgium
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics I BioStat, Hasselt University and Catholic University of Leuven, Agoralaan 1, 3590 Diepenbeek, Belgium
    BMC Infect Dis 9:5. 2009
  8. ncbi Modelling multisera data: the estimation of new joint and conditional epidemiological parameters
    N Hens
    Center for Statistics, Hasselt University, Campus Diepenbeek, Agoralaan Gebouw D, Diepenbeek, Belgium
    Stat Med 27:2651-64. 2008
  9. ncbi Estimating the impact of vaccination using age-time-dependent incidence rates of hepatitis B
    N Hens
    Center for Statistics, Hasselt University, Diepenbeek, Belgium
    Epidemiol Infect 136:341-51. 2008
  10. ncbi Estimating the effective reproduction number for pandemic influenza from notification data made publicly available in real time: a multi-country analysis for influenza A/H1N1v 2009
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Belgium
    Vaccine 29:896-904. 2011

Collaborators

Detail Information

Publications19

  1. ncbi Robust reconstruction and analysis of outbreak data: influenza A(H1N1)v transmission in a school-based population
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Belgium
    Am J Epidemiol 176:196-203. 2012
    ..33 secondary cases per primary case to 0.43 secondary cases per primary case. These results provide quantitative evidence for the change in influenza transmission that is to be expected from school closure...
  2. ncbi Age-disparity, sexual connectedness and HIV infection in disadvantaged communities around Cape Town, South Africa: a study protocol
    Wim Delva
    South African Centre for Epidemiological Modelling and Analysis, Stellenbosch University, 19 Jonkershoek Road, Stellenbosch 7600, South Africa
    BMC Public Health 11:616. 2011
    ....
  3. ncbi Dynamics of HPV vaccination initiation in Flanders (Belgium) 2007-2009: a Cox regression model
    Eva Lefevere
    Herman Deleeck Centre for Social Policy, Antwerp University, St Jacobstraat 2, 2000 Antwerpen, Belgium
    BMC Public Health 11:470. 2011
    ..During this period the initiative for vaccination was taken by the girl, her family or the general practitioner/pediatrician/gynecologist...
  4. ncbi Estimating the impact of school closure on social mixing behaviour and the transmission of close contact infections in eight European countries
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Agoralaan 1, B3590 Diepenbeek, Belgium
    BMC Infect Dis 9:187. 2009
    ..Of particular interest is the potential impact of school closure as a means of controlling pandemic influenza (and potentially other pathogens)...
  5. ncbi Seventy-five years of estimating the force of infection from current status data
    N Hens
    Interuniversity Institute of Biostatistics and Statistical Bioinformatics, Hasselt University, B 3590 Diepenbeek, Belgium
    Epidemiol Infect 138:802-12. 2010
    ..We also provide guidance on deciding which method(s) to apply to estimate the force of infection, given a particular set of data...
  6. ncbi The correlated and shared gamma frailty model for bivariate current status data: an illustration for cross-sectional serological data
    N Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Limburg, Belgium
    Stat Med 28:2785-800. 2009
    ..We show that applying a shared rather than a correlated frailty model to cross-sectionally collected serological data on hepatitis A and B leads to biased estimates for the baseline hazard and variance parameters...
  7. ncbi Mining social mixing patterns for infectious disease models based on a two-day population survey in Belgium
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics I BioStat, Hasselt University and Catholic University of Leuven, Agoralaan 1, 3590 Diepenbeek, Belgium
    BMC Infect Dis 9:5. 2009
    ..In contrast to other European surveys conducted simultaneously, each respondent recorded contacts over two days. Special attention was given to holiday periods, and respondents with large numbers of professional contacts...
  8. ncbi Modelling multisera data: the estimation of new joint and conditional epidemiological parameters
    N Hens
    Center for Statistics, Hasselt University, Campus Diepenbeek, Agoralaan Gebouw D, Diepenbeek, Belgium
    Stat Med 27:2651-64. 2008
    ..Furthermore, we show how to test for association and whether the infection-specific age-dependent FOI curves are proportional and consequently whether separable mixing in the population holds...
  9. ncbi Estimating the impact of vaccination using age-time-dependent incidence rates of hepatitis B
    N Hens
    Center for Statistics, Hasselt University, Diepenbeek, Belgium
    Epidemiol Infect 136:341-51. 2008
    ..Moreover, we have shown that conditional on an assumed baseline susceptibility percentage, a smooth force-of-infection profile can be obtained from which two local maxima were observed at ages 9 and 24 years...
  10. ncbi Estimating the effective reproduction number for pandemic influenza from notification data made publicly available in real time: a multi-country analysis for influenza A/H1N1v 2009
    Niel Hens
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Belgium
    Vaccine 29:896-904. 2011
    ..In this paper, we show how and in which situations the recorded history of cumulated case counts provides valuable information to estimate the effective reproductive number in an early phase and for a large number of countries...
  11. ncbi Analysing the composition of outpatient antibiotic use: a tutorial on compositional data analysis
    Christel Faes
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, University of Hasselt, Hasselt, Belgium
    J Antimicrob Chemother 66:vi89-94. 2011
    ..The methods are applied to two related research questions, namely the assessment of changes in the relative volume of use of different antibiotic subclasses over time and changes in the absolute volume of antibiotic use...
  12. ncbi Estimating vaccination coverage for the trivalent measles-mumps-rubella vaccine from trivariate serological data
    Nele Goeyvaerts
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Agoralaan 1 Gebouw D, B3590, Diepenbeek, Belgium
    Stat Med 31:1432-49. 2012
    ..For both Belgium and Ireland, all models reveal that the vaccination coverage achieved during the first 15 years since the introduction of measles, mumps, and rubella immunization is insufficient to eliminate measles...
  13. ncbi Model structure analysis to estimate basic immunological processes and maternal risk for parvovirus B19
    Nele Goeyvaerts
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Belgium
    Biostatistics 12:283-302. 2011
    ..When prevaccination serological data are available, the framework developed in this paper could prove worthwhile to investigate these different scenarios for other infections as well, such as cytomegalovirus...
  14. ncbi Application of mixed-effects models to study the country-specific outpatient antibiotic use in Europe: a tutorial on longitudinal data analysis
    Girma Minalu
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, University of Hasselt, Hasselt, Belgium
    J Antimicrob Chemother 66:vi79-87. 2011
    ....
  15. ncbi A mathematical model for HIV and hepatitis C co-infection and its assessment from a statistical perspective
    Amparo Yovanna Castro Sanchez
    Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Agoralaan 1, B3590 Diepenbeek, Belgium
    Epidemics 5:56-66. 2013
    ..The parameters associated with contact rates (sharing syringes) and the transmission rates per syringe-sharing event are shown to play a major role...
  16. ncbi Efficacy of daily intake of Lactobacillus casei Shirota on respiratory symptoms and influenza vaccination immune response: a randomized, double-blind, placebo-controlled trial in healthy elderly nursing home residents
    Karolien Van Puyenbroeck
    Department of Primary and Interdisciplinary Care, University of Antwerp, Antwerp, Belgium
    Am J Clin Nutr 95:1165-71. 2012
    ..Age is associated with immune dysregulation, which results in an increased infection rate and reduced effectiveness of vaccination...
  17. ncbi A sensitivity analysis for shared-parameter models for incomplete longitudinal outcomes
    An Creemers
    I Biostat, Universiteit Hasselt, Diepenbeek, Belgium
    Biom J 52:111-25. 2010
    ..While our focus is on longitudinal outcomes with incomplete outcome data, the ideas developed in this paper are of use whenever a shared-parameter model could be considered...
  18. ncbi Model selection for incomplete and design-based samples
    N Hens
    Center for Statistics, Universiteit Hasselt, Campus Diepenbeek, Agoralaan Gebouw D, B 3590 Diepenbeek, Belgium
    Stat Med 25:2502-20. 2006
    ..The use of the weighted AIC-criterion is illustrated on data from the Belgian Health Interview Survey, which motivated this research. Simulations show its performance in a variety of settings...
  19. ncbi Parvovirus B19 infection in five European countries: seroepidemiology, force of infection and maternal risk of infection
    J Mossong
    Laboratoire Nationale de Santé, Luxembourg, Luxembourg
    Epidemiol Infect 136:1059-68. 2008
    ..69% in England & Wales, 43.5% and 1.24% in Finland, 39.9% and 0.92% in Italy and 36.8% and 1.58% in Poland, respectively. Our study indicates substantial epidemiological differences in Europe regarding parvovirus B19 infection...