Kristien Van Reeth

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. pmc Comparative pathogenesis of an avian H5N2 and a swine H1N1 influenza virus in pigs
    Annebel De Vleeschauwer
    Laboratory of Virology, Faculty of Veterinary Medicine Ghent University, Merelbeke, Belgium
    PLoS ONE 4:e6662. 2009
  2. pmc Serologic cross-reactivity with pandemic (H1N1) 2009 virus in pigs, Europe
    Constantinos S Kyriakis
    Ghent University, Ghent, Belgium
    Emerg Infect Dis 16:96-9. 2010
  3. doi Swine influenza virus vaccines: to change or not to change-that's the question
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Curr Top Microbiol Immunol 370:173-200. 2013
  4. doi Seroprevalence of H1N1, H3N2 and H1N2 influenza viruses in pigs in seven European countries in 2002-2003
    Kristien Van Reeth
    Ghent University, Merelbeke, Belgium
    Influenza Other Respir Viruses 2:99-105. 2008
  5. ncbi Avian and swine influenza viruses: our current understanding of the zoonotic risk
    Kristen Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Belgium
    Vet Res 38:243-60. 2007
  6. ncbi Serological profiles after consecutive experimental infections of pigs with European H1N1, H3N2, and H1N2 swine influenza viruses
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Viral Immunol 19:373-82. 2006
  7. ncbi Prior infection with an H1N1 swine influenza virus partially protects pigs against a low pathogenic H5N1 avian influenza virus
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vaccine 27:6330-9. 2009
  8. ncbi Genetic relationships, serological cross-reaction and cross-protection between H1N2 and other influenza A virus subtypes endemic in European pigs
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virus Res 103:115-24. 2004
  9. ncbi Effect of porcine respiratory coronavirus infection on lipopolysaccharide recognition proteins and haptoglobin levels in the lungs
    Steven Van Gucht
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Microbes Infect 8:1492-501. 2006
  10. pmc Anti-TNF-alpha therapy does not ameliorate disease in a model of acute virus-endotoxin mediated respiratory disease in pigs
    Kalina Atanasova
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Immunol Immunopathol 137:12-9. 2010

Collaborators

Detail Information

Publications28

  1. pmc Comparative pathogenesis of an avian H5N2 and a swine H1N1 influenza virus in pigs
    Annebel De Vleeschauwer
    Laboratory of Virology, Faculty of Veterinary Medicine Ghent University, Merelbeke, Belgium
    PLoS ONE 4:e6662. 2009
    ....
  2. pmc Serologic cross-reactivity with pandemic (H1N1) 2009 virus in pigs, Europe
    Constantinos S Kyriakis
    Ghent University, Ghent, Belgium
    Emerg Infect Dis 16:96-9. 2010
    ..We found more serologic cross-reaction than expected. Data suggest pigs in Europe may have partial immunity to pandemic (H1N1) 2009 virus...
  3. doi Swine influenza virus vaccines: to change or not to change-that's the question
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Curr Top Microbiol Immunol 370:173-200. 2013
    ....
  4. doi Seroprevalence of H1N1, H3N2 and H1N2 influenza viruses in pigs in seven European countries in 2002-2003
    Kristien Van Reeth
    Ghent University, Merelbeke, Belgium
    Influenza Other Respir Viruses 2:99-105. 2008
    ....
  5. ncbi Avian and swine influenza viruses: our current understanding of the zoonotic risk
    Kristen Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Belgium
    Vet Res 38:243-60. 2007
    ....
  6. ncbi Serological profiles after consecutive experimental infections of pigs with European H1N1, H3N2, and H1N2 swine influenza viruses
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Viral Immunol 19:373-82. 2006
    ..In conclusion, the HI test remains adequate for the differential diagnosis of infections with H1N1, H3N2, and H1N2 in European swine populations if it is properly used and if the SIV vaccination status is taken into account...
  7. ncbi Prior infection with an H1N1 swine influenza virus partially protects pigs against a low pathogenic H5N1 avian influenza virus
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vaccine 27:6330-9. 2009
    ..Further studies should reveal whether cross-protection holds against H5N1 viruses that are better adapted to replicate in mammals or with a more distantly related N1...
  8. ncbi Genetic relationships, serological cross-reaction and cross-protection between H1N2 and other influenza A virus subtypes endemic in European pigs
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virus Res 103:115-24. 2004
    ..It is still unknown whether this type of cross-subtype protection will also occur in infection-immune pigs in the field...
  9. ncbi Effect of porcine respiratory coronavirus infection on lipopolysaccharide recognition proteins and haptoglobin levels in the lungs
    Steven Van Gucht
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Microbes Infect 8:1492-501. 2006
    ..The marked increases in LBP, CD14 and haptoglobin were not correlated with the extent of the LPS response...
  10. pmc Anti-TNF-alpha therapy does not ameliorate disease in a model of acute virus-endotoxin mediated respiratory disease in pigs
    Kalina Atanasova
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Immunol Immunopathol 137:12-9. 2010
    ....
  11. pmc Lipoteichoic acid from Staphylococcus aureus exacerbates respiratory disease in porcine respiratory coronavirus-infected pigs
    Kalina Atanasova
    Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet J 188:210-5. 2011
    ..Given that Gram-positive bacteria, capable of producing LTA, are commonly found in pig accommodation, the role of this compound in the development of the porcine respiratory disease complex requires further investigation...
  12. ncbi Porcine reproductive and respiratory syndrome virus infection increases CD14 expression and lipopolysaccharide-binding protein in the lungs of pigs
    Steven Van Gucht
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, B 9820 Merelbeke, Belgium
    Viral Immunol 18:116-26. 2005
    ..As both CD14 and LBP potentiate the inflammatory effects of LPS, their increase in the lungs could explain why PRRSV sensitizes the lungs for the production of proinflammatory cytokines and respiratory signs upon exposure to LPS...
  13. ncbi Performance of a commercial Swine influenza virus H1N1 and H3N2 antibody enzyme-linked immunosorbent assay in pigs experimentally infected with European influenza viruses
    Filip Barbé
    Faculty of Veterinary Medicine, Laboratory of Virology, Ghent University, Merelbeke, Belgium
    J Vet Diagn Invest 21:88-96. 2009
    ..However, the interpretation of ELISA results will be difficult, and HI remains the method of choice...
  14. ncbi Apoptosis in the lungs of pigs infected with porcine reproductive and respiratory syndrome virus and associations with the production of apoptogenic cytokines
    Geoffrey Labarque
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Res 34:249-60. 2003
    ..However, the latter hypothesis was not confirmed in vitro, since blood monocytes or alveolar macrophages did not undergo apoptosis after treatment with recombinant porcine IL-1 or IL-10...
  15. ncbi Protection against a European H1N2 swine influenza virus in pigs previously infected with H1N1 and/or H3N2 subtypes
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vaccine 21:1375-81. 2003
    ..Given the severe challenge model used here, cross-protection against H1N2 could be more pronounced under natural conditions of infection...
  16. doi Safety, immunogenicity and efficacy of poxvirus-based vector vaccines expressing the haemagglutinin gene of a highly pathogenic H5N1 avian influenza virus in pigs
    Constantinos S Kyriakis
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vaccine 27:2258-64. 2009
    ..It remains to be seen whether they would protect against a swine-adapted H5 virus, which may replicate 100-1000 times better than our challenge virus...
  17. doi Cytokines and acute phase proteins associated with acute swine influenza infection in pigs
    Filip Barbé
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet J 187:48-53. 2011
    ..The findings suggest that IFN-γ and IL-12 play a role in the pathogenesis of SIV and that APPs are induced by cytokines. This influenza infection model may have value in assessing the therapeutic potential of cytokine antagonists...
  18. ncbi The combination of PRRS virus and bacterial endotoxin as a model for multifactorial respiratory disease in pigs
    Steven Van Gucht
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Immunol Immunopathol 102:165-78. 2004
    ..To what extent the interaction between PRRSV and LPS contributes to the development of complex respiratory disease is still a matter of debate...
  19. doi Efficient transmission of swine-adapted but not wholly avian influenza viruses among pigs and from pigs to ferrets
    Annebel De Vleeschauwer
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, B 9820 Merelbeke, Belgium
    J Infect Dis 200:1884-92. 2009
    ..Pigs are considered to be intermediate hosts for the transmission of avian influenza viruses (AIVs) between birds and humans, but the transmissibility of AIVs among pigs and from pigs to other mammals remains largely unexplored...
  20. pmc Interaction between porcine reproductive-respiratory syndrome virus and bacterial endotoxin in the lungs of pigs: potentiation of cytokine production and respiratory disease
    Steven Van Gucht
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, B 9820 Merelbeke, Belgium
    J Clin Microbiol 41:960-6. 2003
    ..These data demonstrate a synergism between PRRSV and LPS in the induction of proinflammatory cytokines and an association between induction of these cytokines and disease...
  21. doi Effect of receptor specificity of A/Hong Kong/1/68 (H3N2) influenza virus variants on replication and transmission in pigs
    Sjouke Van Poucke
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Influenza Other Respir Viruses 7:151-9. 2013
    ..How virus receptor binding specificity affects transmission in pigs, on the other hand, has not been studied so far...
  22. doi Efficacy of an AS03A-adjuvanted split H5N1 influenza vaccine against an antigenically distinct low pathogenic H5N1 virus in pigs
    Annebel R De Vleeschauwer
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vaccine 30:5557-63. 2012
    ..The pros and cons of the pig as an H5N1 challenge model are also discussed...
  23. doi Prior infection of pigs with swine influenza viruses is a barrier to infection with avian influenza viruses
    Annebel De Vleeschauwer
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 146:340-5. 2010
    ..Serological screening in regions where SIV is enzootic is only useful when the AIV strain for which the pigs need to be tested is known...
  24. ncbi Prior infection of pigs with a recent human H3N2 influenza virus confers minimal cross-protection against a European swine H3N2 virus
    Yu Qiu
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Influenza Other Respir Viruses 7:1260-8. 2013
    ..It remains unknown to what extent this results in a reduced cross-protection between recent human and swine H3N2 influenza viruses...
  25. ncbi In vivo studies on cytokine involvement during acute viral respiratory disease of swine: troublesome but rewarding
    Kristien Van Reeth
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Immunol Immunopathol 87:161-8. 2002
    ..TNF-alpha and IL-6 were best correlated with disease. In further studies, we will use more specific strategies to dissect the role of cytokines during viral infections...
  26. doi Cross-protection between antigenically distinct H1N1 swine influenza viruses from Europe and North America
    Annebel R De Vleeschauwer
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Influenza Other Respir Viruses 5:115-22. 2011
    ..However, the significance of this antigenic difference for cross-protection among pigs remains unknown...
  27. doi Role of IFN-alpha during the acute stage of a swine influenza virus infection
    Filip Barbé
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Res Vet Sci 88:172-8. 2010
    ..These results suggest an important role for IFN-alpha in IL-6 and IL-12 induction and a role of all three cytokines in the symptoms of swine influenza...
  28. pmc Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distribution
    Sjouke G M Van Poucke
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virol J 7:38. 2010
    ..Human (Sia alpha2-6Gal) and avian virus receptors (Sia alpha2-3Gal) were identified with Sambucus Nigra and Maackia amurensis lectins respectively...