Filip Van Immerseel

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. ncbi request reprint Protection of laying hens against Salmonella Enteritidis by immunization with type 1 fimbriae
    Jeroen De Buck
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 105:93-101. 2005
  2. ncbi request reprint The use of organic acids to combat Salmonella in poultry: a mechanistic explanation of the efficacy
    F Van Immerseel
    Ghent University, Faculty of Veterinary Medicine, Research Group Veterinary Public Health and Zoonoses, Department of Pathology, Bacteriology and Avian Diseases, Salisburylaan 133, B 9820, Merelbeke, Belgium
    Avian Pathol 35:182-8. 2006
  3. doi request reprint Clostridium perfringens strains from bovine enterotoxemia cases are not superior in in vitro production of alpha toxin, perfringolysin O and proteolytic enzymes
    Evy Goossens
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    BMC Vet Res 10:32. 2014
  4. ncbi request reprint Salmonella Gallinarum field isolates from laying hens are related to the vaccine strain SG9R
    F Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium Electronic address
    Vaccine 31:4940-5. 2013
  5. pmc The synergistic necrohemorrhagic action of Clostridium perfringens perfringolysin and alpha toxin in the bovine intestine and against bovine endothelial cells
    Stefanie Verherstraeten
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke B 9820, Belgium
    Vet Res 44:45. 2013
  6. pmc The influence of the cage system and colonisation of Salmonella Enteritidis on the microbial gut flora of laying hens studied by T-RFLP and 454 pyrosequencing
    Steen Nordentoft
    National Veterinary Institute, Technical University of Denmark, Section for Poultry, Fish and Fur Animals, Hangovej 2, DK 8200 Aarhus N, Denmark
    BMC Microbiol 11:187. 2011
  7. ncbi request reprint Mutations influencing expression of the Salmonella enterica serovar Enteritidis pathogenicity island I key regulator hilA
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Antonie Van Leeuwenhoek 94:455-61. 2008
  8. ncbi request reprint Supplementation of coated butyric acid in the feed reduces colonization and shedding of Salmonella in poultry
    F Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Poult Sci 84:1851-6. 2005
  9. ncbi request reprint Clostridium perfringens in poultry: an emerging threat for animal and public health
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Avian Pathol 33:537-49. 2004
  10. ncbi request reprint The effect of oral administration of a homologous hilA mutant strain on the long-term colonization and transmission of Salmonella Enteritidis in broiler chickens
    Lotte Bohez
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vaccine 26:372-8. 2008

Collaborators

Detail Information

Publications56

  1. ncbi request reprint Protection of laying hens against Salmonella Enteritidis by immunization with type 1 fimbriae
    Jeroen De Buck
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 105:93-101. 2005
    ..in the immunized hens but not in the control hens. In conclusion, we demonstrated that the immunization of laying hens with type 1 fimbriae reduced the number of contaminated eggs and reduced the colonization of the reproductive organs...
  2. ncbi request reprint The use of organic acids to combat Salmonella in poultry: a mechanistic explanation of the efficacy
    F Van Immerseel
    Ghent University, Faculty of Veterinary Medicine, Research Group Veterinary Public Health and Zoonoses, Department of Pathology, Bacteriology and Avian Diseases, Salisburylaan 133, B 9820, Merelbeke, Belgium
    Avian Pathol 35:182-8. 2006
    ..If diets can be designed to stimulate organic acid production in the caecum, it may be possible to control Salmonella spp. via even easier and more cost-effective measures, compared with addition of acids to feed or drinking water...
  3. doi request reprint Clostridium perfringens strains from bovine enterotoxemia cases are not superior in in vitro production of alpha toxin, perfringolysin O and proteolytic enzymes
    Evy Goossens
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    BMC Vet Res 10:32. 2014
    ..To approach this, a collection of strains originating from enterotoxemia cases was compared to bovine strains isolated from healthy animals and to strains isolated from other animal species...
  4. ncbi request reprint Salmonella Gallinarum field isolates from laying hens are related to the vaccine strain SG9R
    F Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium Electronic address
    Vaccine 31:4940-5. 2013
    ..Mutations in the aceE and rfaJ genes could explain the reversion to a more virulent phenotype. Our results highlight the importance of using well defined gene deletion mutants as vaccines. ..
  5. pmc The synergistic necrohemorrhagic action of Clostridium perfringens perfringolysin and alpha toxin in the bovine intestine and against bovine endothelial cells
    Stefanie Verherstraeten
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke B 9820, Belgium
    Vet Res 44:45. 2013
    ....
  6. pmc The influence of the cage system and colonisation of Salmonella Enteritidis on the microbial gut flora of laying hens studied by T-RFLP and 454 pyrosequencing
    Steen Nordentoft
    National Veterinary Institute, Technical University of Denmark, Section for Poultry, Fish and Fur Animals, Hangovej 2, DK 8200 Aarhus N, Denmark
    BMC Microbiol 11:187. 2011
    ..The distribution of genera in the microbiota in caecum was furthermore described by next generation sequencing of 16S rDNA libraries...
  7. ncbi request reprint Mutations influencing expression of the Salmonella enterica serovar Enteritidis pathogenicity island I key regulator hilA
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Antonie Van Leeuwenhoek 94:455-61. 2008
    ..Mutants having decreased and increased hilA expression were more and less invasive in the human colon carcinoma cell line T84 compared to wild type strain bacteria, respectively...
  8. ncbi request reprint Supplementation of coated butyric acid in the feed reduces colonization and shedding of Salmonella in poultry
    F Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Poult Sci 84:1851-6. 2005
    ..enteritidis bacteria in the ceca at slaughter age, although at enrichment level...
  9. ncbi request reprint Clostridium perfringens in poultry: an emerging threat for animal and public health
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Avian Pathol 33:537-49. 2004
    ..The most cost-effective control will probably be achieved by balancing the composition of the feed...
  10. ncbi request reprint The effect of oral administration of a homologous hilA mutant strain on the long-term colonization and transmission of Salmonella Enteritidis in broiler chickens
    Lotte Bohez
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vaccine 26:372-8. 2008
    ....
  11. pmc Stress-induced survival strategies enable Salmonella Enteritidis to persistently colonize the chicken oviduct tissue and cope with antimicrobial factors in egg white: A hypothesis to explain a pandemic
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Gut Pathog 2:23. 2010
    ..Salmonella Enteritidis is much more capable to persistently colonize the laying hen reproductive tract and to survive in the hostile egg white, as compared to other serotypes...
  12. ncbi request reprint Intermittent long-term shedding and induction of carrier birds after infection of chickens early posthatch with a low or high dose of Salmonella enteritidis
    F Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Poult Sci 83:1911-6. 2004
    ..It can be concluded that infection of newly hatched chicks with a low dose of Salmonella Enteritidis can lead to persistent infection until onset of lay, hereby excreting Salmonella bacteria intermittently...
  13. pmc Medium-chain fatty acids decrease colonization and invasion through hilA suppression shortly after infection of chickens with Salmonella enterica serovar Enteritidis
    F Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, B 9820 Merelbeke, Belgium
    Appl Environ Microbiol 70:3582-7. 2004
    ..Thus, MCFA are potentially useful products for reducing the level of colonization of chicks and could ultimately aid in the reduction of the number of contaminated eggs in the food supply...
  14. doi request reprint Isolation of a clonal population of Clostridium perfringens type A from a Belgian Blue calf with abomasal ulceration
    F Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    J Comp Pathol 143:289-93. 2010
    ..Clostridium perfringens type A was isolated from multiple ulcers and from the intestinal contents of the animal and pulsed field gel electrophoresis confirmed that the isolates comprised a genetically clonal population...
  15. ncbi request reprint The Salmonella Pathogenicity Island 2 regulator ssrA promotes reproductive tract but not intestinal colonization in chickens
    Lotte Bohez
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 126:216-24. 2008
    ..These findings indicate that the SPI-2 regulator ssrA promotes reproductive tract colonization, but is not essential for intestinal colonization of chickens with the host non-specific serotype Enteritidis...
  16. ncbi request reprint A limited role for SsrA/B in persistent Salmonella Typhimurium infections in pigs
    Filip Boyen
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 128:364-73. 2008
    ..These results suggest that the ssrA/B gene of Salmonella Typhimurium plays a limited role in the persistent intestinal colonization of pigs...
  17. doi request reprint Origin of Clostridium perfringens isolates determines the ability to induce necrotic enteritis in broilers
    Leen Timbermont
    Research Group Veterinary Public Health and Zoonoses, Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, B 9820 Merelbeke, Belgium
    Comp Immunol Microbiol Infect Dis 32:503-12. 2009
    ..These results suggest the presence of host specific virulence factors in C. perfringens strains, isolated from chickens with intestinal necrotic enteritis lesions...
  18. doi request reprint Colonization strategy of Campylobacter jejuni results in persistent infection of the chicken gut
    Kim Van Deun
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Vet Microbiol 130:285-97. 2008
    ..These findings suggest a novel colonization mechanism by escaping rapid mucosal clearance through short-term epithelial invasion and evasion, combined with fast replication in the mucus...
  19. ncbi request reprint The effect of vaccination with a Salmonella enteritidis aroA mutant on early cellular responses in caecal lamina propria of newly-hatched chickens
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vaccine 20:3034-41. 2002
    ....
  20. doi request reprint Short-chain fatty acids and L-lactate as feed additives to control Campylobacter jejuni infections in broilers
    Kim Van Deun
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Merelbeke, Belgium
    Avian Pathol 37:379-83. 2008
    ..jejuni in the applied test conditions. This might be partially ascribed to the protective effect of mucous and the rapid absorption of butyrate by the enterocytes...
  21. ncbi request reprint Salmonella enterica serovar Enteritidis colonization of the chicken caecum requires the HilA regulatory protein
    Lotte Bohez
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 116:202-10. 2006
    ..It is concluded that hilA is involved in long-term shedding and colonization of S. Enteritidis in the chicken caeca...
  22. ncbi request reprint Oral immunisation of laying hens with the live vaccine strains of TAD Salmonella vac E and TAD Salmonella vac T reduces internal egg contamination with Salmonella Enteritidis
    Inne Gantois
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vaccine 24:6250-5. 2006
    ..In conclusion, these data indicate that vaccination of laying hens with these live vaccines could be considered as a valuable tool in controlling internal egg contamination...
  23. doi request reprint Poultry as a host for the zoonotic pathogen Campylobacter jejuni
    David Hermans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Vector Borne Zoonotic Dis 12:89-98. 2012
    ..jejuni in broiler flocks. As a result, the number of human campylobacteriosis cases associated with the chicken vector remains strikingly high...
  24. ncbi request reprint Long-term colonisation-inhibition studies to protect broilers against colonisation with Salmonella Enteritidis, using Salmonella Pathogenicity Island 1 and 2 mutants
    Lotte Bohez
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vaccine 25:4235-43. 2007
    ..The approach of vaccination with a hilA mutant strain can be a valuable basis for development of vaccine strains for broilers protection...
  25. doi request reprint Anaerostipes butyraticus sp. nov., an anaerobic, butyrate-producing bacterium from Clostridium cluster XIVa isolated from broiler chicken caecal content, and emended description of the genus Anaerostipes
    Venessa Eeckhaut
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Int J Syst Evol Microbiol 60:1108-12. 2010
    ..nov. is proposed. The type strain is 35-7(T) (=LMG 24724(T) =DSM 22094(T)). An emended description of the genus Anaerostipes is also provided...
  26. pmc Colonization factors of Campylobacter jejuni in the chicken gut
    David Hermans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Res 42:82. 2011
    ..jejuni identified to date. These factors may contribute to our understanding on how C. jejuni survival and colonization in chicks is mediated, as well as provide potential targets for effective subunit vaccine development...
  27. doi request reprint Campylobacter control in poultry by current intervention measures ineffective: urgent need for intensified fundamental research
    David Hermans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Microbiol 152:219-28. 2011
    ..This review gives an up-to-date overview of suggested on-farm control measures to reduce the prevalence and colonization of Campylobacter in poultry...
  28. ncbi request reprint Quantification of gut lesions in a subclinical necrotic enteritis model
    Ahmad R Gholamiandehkordi
    Research Group Veterinary Public Health and Zoonoses, Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Avian Pathol 36:375-82. 2007
    ..perfringens inoculations is a suitable model for necrotic enteritis without inducing mortality of the animals. C. perfringens and Eimeria act synergistically in inducing grossly visible gut damage...
  29. doi request reprint The cinnamon-oil ingredient trans-cinnamaldehyde fails to target Campylobacter jejuni strain KC 40 in the broiler chicken cecum despite marked in vitro activity
    David Hermans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    J Food Prot 74:1729-34. 2011
    ..jejuni numbers were not reduced compared with those in nontreated ceca at 2 and 24 h after injection. In conclusion, this study shows a marked discrepancy between in vitro and in vivo activity of CIN against C. jejuni strain KC 40...
  30. ncbi request reprint Virulence properties of Campylobacter jejuni isolates of poultry and human origin
    Kim Van Deun
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Med Microbiol 56:1284-9. 2007
    ..These data suggest that all four virulence properties are widespread among C. jejuni isolates, but that a higher degree of bile-salt resistance and more pronounced CDT production are associated with strains causing enteritis in humans...
  31. pmc Cats as a risk for transmission of antimicrobial drug-resistant Salmonella
    Filip Van Immerseel
    Ghent University, Merelbeke, Belgium
    Emerg Infect Dis 10:2169-74. 2004
    ..Cats that excrete Salmonella can pose a public health hazard to people who are highly susceptible to Salmonella, such as children, the elderly, and immunocompromised persons...
  32. ncbi request reprint Salmonella Typhimurium SPI-1 genes promote intestinal but not tonsillar colonization in pigs
    Filip Boyen
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Microbes Infect 8:2899-907. 2006
    ..This study shows that SPI-1 plays a crucial role in the invasion and colonization of the porcine gut and in the induction of influx of neutrophils towards the intestinal lumen, but not in the colonization of the tonsils...
  33. doi request reprint A tolerogenic mucosal immune response leads to persistent Campylobacter jejuni colonization in the chicken gut
    David Hermans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Crit Rev Microbiol 38:17-29. 2012
    ..jejuni in chicks and to develop effective control measures to clear this zoonotic pathogen from poultry lines...
  34. doi request reprint Intra-species growth-inhibition by Clostridium perfringens is a possible virulence trait in necrotic enteritis in broilers
    Leen Timbermont
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 137:388-91. 2009
    ..It is proposed that, in addition to toxin production, intra-species growth-inhibition may be a virulence trait that contributes to the ability of certain C. perfringens strains to cause necrotic enteritis in broilers...
  35. pmc Induction of the carrier state in pigeons infected with Salmonella enterica subspecies enterica serovar typhimurium PT99 by treatment with florfenicol: a matter of pharmacokinetics
    Frank Pasmans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Antimicrob Agents Chemother 52:954-61. 2008
    ..In conclusion, the oral application of florfenicol for the treatment of pigeon paratyphoid contributes to the development of carrier animals through sub-MIC concentrations in plasma that do not inhibit intracellular persistency...
  36. doi request reprint The cereal type in feed influences gut wall morphology and intestinal immune cell infiltration in broiler chickens
    Emma Teirlynck
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Br J Nutr 102:1453-61. 2009
    ..In conclusion, a wheat/rye-based diet evoked mucosal damage, an alteration in the composition of the microbiota and an inflammatory bowel type of condition...
  37. ncbi request reprint Molecular and phenotypical characterization of Clostridium perfringens isolates from poultry flocks with different disease status
    Ahmad R Gholamiandekhordi
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 113:143-52. 2006
    ..It was shown that in vitro alpha toxin production of C. perfringens isolates from diseased flocks was not higher than in vitro alpha toxin production from isolates derived from healthy flocks...
  38. pmc Assessment of virulence of pigeon isolates of Salmonella enterica subsp. enterica serovar typhimurium variant copenhagen for humans
    Frank Pasmans
    Department of Pathology, Bacteriology, and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium
    J Clin Microbiol 42:2000-2. 2004
    ..However, the high virulence for mice of the tested strain implies that rodents may act as reservoirs...
  39. ncbi request reprint Butyrate protects Caco-2 cells from Campylobacter jejuni invasion and translocation
    Kim Van Deun
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium
    Br J Nutr 100:480-4. 2008
    ..The present study showed that butyrate is able to protect Caco-2 cells from two major virulence mechanisms of C. jejuni, namely invasion and translocation, but not from a decline in transepithelial resistance...
  40. doi request reprint Antimicrobial resistance in Clostridium perfringens isolates from broilers in Belgium
    Ahmadreza Gholamiandehkordi
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Res Commun 33:1031-7. 2009
    ..These data are consistent with data derived from studies carried out in 1980 and in 2004, indicating that no changes in antimicrobial resistance patterns have taken place during time in C. perfringens isolates from broilers in Belgium...
  41. doi request reprint Day-of-hatch vaccination is not protective against necrotic enteritis in broiler chickens
    Dorien Mot
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Avian Pathol 42:179-84. 2013
    ..Single vaccination with crude supernatant at day 3 resulted in significant protection, while vaccination of 1-day-old chickens with crude supernatant or toxoid, as envisaged for practical field application, did not induce protection...
  42. ncbi request reprint Dynamics of immune cell infiltration in the caecal lamina propria of chickens after neonatal infection with a Salmonella enteritidis strain
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820, Merelbeke, Belgium
    Dev Comp Immunol 26:355-64. 2002
    ..The structural maturation of the mucosa-associated lymphoid tissues is antigen driven, since B-cells organise in a follicular pattern...
  43. ncbi request reprint Interactions of butyric acid- and acetic acid-treated Salmonella with chicken primary cecal epithelial cells in vitro
    Filip Van Immerseel
    Department of Pathology, Bacteriology, and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Avian Dis 48:384-91. 2004
    ..These interactions of S. enteritidis with primary chicken cecal epithelial cells were similar to the interactions with other epithelial cell types...
  44. ncbi request reprint Effect of type 1 fimbriae of Salmonella enterica serotype Enteritidis on bacteraemia and reproductive tract infection in laying hens
    Jeroen De Buck
    Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Avian Pathol 33:314-20. 2004
    ..Thus, the absence of type 1 fimbriae prolongs bacteraemia, modifies reproductive tract infection and reduces egg shell contamination by Salmonella enterica serovar Enteritidis...
  45. doi request reprint Mechanisms of egg contamination by Salmonella Enteritidis
    Inne Gantois
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Research Group Veterinary Public Health and Zoonoses, Ghent University, Merelbeke, Belgium
    FEMS Microbiol Rev 33:718-38. 2009
    ..This appears to require a unique combination of genes encoding for improved cell wall protection and repairing cellular and molecular damage, among others...
  46. ncbi request reprint Butyricicoccus pullicaecorum gen. nov., sp. nov., an anaerobic, butyrate-producing bacterium isolated from the caecal content of a broiler chicken
    Venessa Eeckhaut
    Department of Pathology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Int J Syst Evol Microbiol 58:2799-802. 2008
    ..nov., sp. nov. The type strain of Butyricicoccus pullicaecorum is 25-3(T) (=LMG 24109(T) =CCUG 55265(T)). The DNA G+C content of strain 25-3(T) was 54.5 mol% ...
  47. pmc Host adaptation of pigeon isolates of Salmonella enterica subsp. enterica serovar Typhimurium variant Copenhagen phage type 99 is associated with enhanced macrophage cytotoxicity
    Frank Pasmans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Infect Immun 71:6068-74. 2003
    ..These data suggest that the phage type 99 strains used in this study are highly adapted to pigeons and should be classified as a host-restricted lineage of the serovar Typhimurium...
  48. ncbi request reprint Adhesion of Salmonella enterica serotype Enteritidis isolates to chicken isthmal glandular secretions
    Jeroen De Buck
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 93:223-33. 2003
    ..It is hypothesized that the binding of S. Enteritidis to isthmal secretions could play a role in the contamination of eggs through incorporation of the bacteria in the shell membranes...
  49. doi request reprint Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Trends Microbiol 17:32-6. 2009
    ..Recent research is creating a paradigm shift in our understanding of the pathogenesis of NE and is now providing information that will be necessary to monitor and control the incidence of NE in poultry...
  50. doi request reprint Butyricicoccus pullicaecorum in inflammatory bowel disease
    Venessa Eeckhaut
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Faculty of Veterinary Medicine, Merelbeke, Belgium
    Gut 62:1745-52. 2013
    ..We evaluated the effect of Butyricicoccus pullicaecorum in a rat colitis model and analysed the ability to prevent cytokine-induced increases in epithelial permeability...
  51. doi request reprint The impact of Fusarium mycotoxins on human and animal host susceptibility to infectious diseases
    Gunther Antonissen
    Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Toxins (Basel) 6:430-52. 2014
    ....
  52. doi request reprint Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli
    Pieter Van den Abbeele
    Laboratory of Microbial Ecology and Technology LabMET, Ghent University, Coupure Links 653, B 9000 Ghent, Belgium
    Microb Biotechnol 5:106-15. 2012
    ..This may lead to more in vivo-like microbial communities in such dynamic, long-term in vitro simulations and allow the study of the unique mucosal microbiota in health and disease...
  53. doi request reprint Detection of Batrachochytrium dendrobatidis in Mexican bolitoglossine salamanders using an optimal sampling protocol
    Pascale Van Rooij
    Laboratory of Bacteriology and Mycology, Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Ecohealth 8:237-43. 2011
    ....
  54. ncbi request reprint Perfrin, a novel bacteriocin associated with netB positive Clostridium perfringens strains from broilers with necrotic enteritis
    Leen Timbermont
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Res 45:40. 2014
    ..C. perfringens bacteriocins, such as perfrin, can be considered as an additional factor involved in the pathogenesis of necrotic enteritis in broilers. ..
  55. pmc A live Salmonella enterica serovar Enteritidis vaccine allows serological differentiation between vaccinated and infected animals
    Connie Adriaensen
    Viral Genetics Laboratory, Vrije Universiteit Brussel, Pleinlaan 2, B 1050 Brussels, Belgium
    Infect Immun 75:2461-8. 2007
    ..enterica serovar Enteritidis challenge strain but not against intestinal colonization. These data demonstrate that nonflagellated attenuated Salmonella mutants can be used as marker vaccines...