Research Topics
| Annemieke SmetSummaryAffiliation: Ghent University Country: Belgium Publications
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Publications
Diversity of extended-spectrum beta-lactamases and class C beta-lactamases among cloacal Escherichia coli Isolates in Belgian broiler farmsAnnemieke Smet
Department of Bacteriology and Immunology, CODA CERVA VAR, Groeselenberg 99, 1180 Brussels, Belgium
Antimicrob Agents Chemother 52:1238-43. 2008..coli strains are often present in cloacal samples of broilers at the farm level in Belgium. The diversity of broad-spectrum beta-lactamases among these isolates is high, and they may act as a reservoir of ESBL and ampC genes...
Broad-spectrum β-lactamases among Enterobacteriaceae of animal origin: molecular aspects, mobility and impact on public healthAnnemieke Smet
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
FEMS Microbiol Rev 34:295-316. 2010....- Helicobacter heilmannii sp. nov., isolated from feline gastric mucosaA Smet
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
Int J Syst Evol Microbiol 62:299-306. 2012..The name Helicobacter heilmannii sp. nov. is proposed for these isolates; the type strain is ASB1(T) (=DSM 24751 (T) =LMG 26292(T)) [corrected]... - In situ ESBL conjugation from avian to human Escherichia coli during cefotaxime administrationA Smet
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan, Merelbeke, Belgium
J Appl Microbiol 110:541-9. 2011.... - Complete nucleotide sequence of CTX-M-15-plasmids from clinical Escherichia coli isolates: insertional events of transposons and insertion sequencesAnnemieke Smet
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
PLoS ONE 5:e11202. 2010..CTX-M-producing Escherichia coli strains are regarded as major global pathogens... - Characterization of extended-spectrum beta-lactamases produced by Escherichia coli isolated from hospitalized and nonhospitalized patients: emergence of CTX-M-15-producing strains causing urinary tract infectionsAnnemieke Smet
Department of Pathology, Bacteriology, and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
Microb Drug Resist 16:129-34. 2010..coli isolates in the hospital and community in Belgium. Of particular concern is the predominant presence of the CTX-M-15 enzyme in ST131 community-acquired E. coli... - The importance of sample size in the determination of a flock-level antimicrobial resistance profile for Escherichia coli in broilersDavy Persoons
Veterinary Epidemiology Unit, Department of Obstetrics, Reproduction, and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium
Microb Drug Resist 17:513-9. 2011..Results show that focus should be on the number of animals sampled rather than on the number of isolates tested within one animal... - Prevalence and persistence of antimicrobial resistance in broiler indicator bacteriaDavy Persoons
Veterinary Epidemiology Unit, Department of Obstetrics, Reproduction, and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke 820, Belgium
Microb Drug Resist 16:67-74. 2010..coli and E. faecium. For E. coli but not for E. faecium, the resistance profile of neck skin isolates was different from that of cloacal isolates... - Antimicrobial use in Belgian broiler productionDavy Persoons
Department of Obstetrics, Reproduction and Herd Health, Veterinary Epidemiology Unit, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
Prev Vet Med 105:320-5. 2012..7, respectively. The ratio of the UDD/DDD gives an estimate on correctness of dosing. Tylosin was underdosed in most of the administrations whereas amoxicillin and trimethoprim-sulphonamide were slightly overdosed in the average flock... - Gastric epithelial cell death caused by Helicobacter suis and Helicobacter pylori γ-glutamyl transpeptidase is mainly glutathione degradation-dependentBram Flahou
Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Merelbeke, Belgium
Cell Microbiol 13:1933-55. 2011..suis and H. pylori GGT-mediated generation of pro-oxidant glutathione degradation products brings on cell damage and causes apoptosis or necrosis, dependent on the amount of extracellular glutathione available as a GGT substrate... - The other HelicobactersAnnemieke Smet
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
Helicobacter 16:70-5. 2011..Molecular studies have also elucidated the mechanism of action of some functional components of these organisms... - Immunization with the immunodominant Helicobacter suis urease subunit B induces partial protection against H. suis infection in a mouse modelMiet Vermoote
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
Vet Res 43:72. 2012..suis-infected controls, whereas rNapA had no significant protective effect. Probably, a combination of local Th1 and Th17 responses, complemented by antibody responses play a role in the protective immunity against H. suis infections... - Multilocus sequence typing of the porcine and human gastric pathogen Helicobacter suisJungang Liang
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
J Clin Microbiol 51:920-6. 2013..The human H. suis strain showed a very close relationship to porcine strains. In conclusion, the developed MLST scheme may prove useful for direct, culture-independent typing of porcine and human H. suis strains... - The local immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pyloriBram Flahou
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, 9820, Belgium
Vet Res 43:75. 2012..suis strains and the immune response they evoke. A predominant Th17 response was observed, accompanied by a mild Th2 response, which is different from the Th17/Th1 response evoked by H. pylori infection... - Helicobacter suis causes severe gastric pathology in mouse and mongolian gerbil models of human gastric diseaseBram Flahou
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
PLoS ONE 5:e14083. 2010..suis, a bacterium which is mainly associated with pigs. To obtain better insights into the long-term pathogenesis of infections with this micro-organism, experimental infections were carried out in different rodent models... - Genome sequence of Helicobacter suis supports its role in gastric pathologyMiet Vermoote
Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
Vet Res 42:51. 2011..pylori, such as the cytotoxin-associated protein (CagA), are not detected in the H. suis genome, homologs of other genes associated with colonization and virulence of H. pylori and other bacteria are present...