Frank Roels

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. ncbi request reprint Peroxisomes during development and in distinct cell types
    Frank Roels
    Dept of Pathology, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium
    Adv Exp Med Biol 544:39-54. 2003
  2. ncbi request reprint Peroxisome mosaics
    Frank Roels
    Dept Pathology, Ghent University, Belgium
    Adv Exp Med Biol 544:97-106. 2003
  3. ncbi request reprint Why study regulation of genes in inherited disorders?
    Frank Roels
    Department of Pathology, Ghent University, University Hospital, De Pintelaan 185, 9000 Gent, Belgium
    Adv Exp Med Biol 544:1-8. 2003
  4. pmc Mitochondrial mosaics in the liver of 3 infants with mtDNA defects
    Frank Roels
    Department of Pathology, Ghent University Hospital, Block A, De Pintelaan 185, 9000 Gent, Belgium
    BMC Clin Pathol 9:4. 2009
  5. ncbi request reprint Modified peroxisomes in primary hepatocyte cultures
    Marianne Depreter
    Ghent University, Dept Human Anatomy, Embryology, Histology, and Medical Physics, Godshuizenlaan 4, B 9000 Gent, Belgium
    Adv Exp Med Biol 544:255-64. 2003
  6. ncbi request reprint Regulation of peroxisomal genes by DHEA and vitamin D
    Marianne Depreter
    Department of Human Anatomy, Embryology, Histology and Medical Physics, Ghent University, B 9000 Gent, Belgium
    Adv Exp Med Biol 544:237-42. 2003
  7. ncbi request reprint Hepatocyte polarity and the peroxisomal compartment: a comparative study
    Marianne Depreter
    Department of Human Anatomy, Embryology, Histology, and Medical Physics, Ghent University, Godshuizenlaan 4, B 9000 Gent, Belgium
    Histochem J 34:139-51. 2002
  8. ncbi request reprint Human peroxisomal disorders
    Marianne Depreter
    Ghent University, Department of Human Anatomy, Embryology, Histology and Medical Physics, Belgium
    Microsc Res Tech 61:203-23. 2003
  9. pmc No evidence for involvement of SDHD in neuroblastoma pathogenesis
    Katleen De Preter
    Center for Medical Genetics, Ghent University Hospital, K5, De Pintelaan 185, B 9000 Ghent, Belgium
    BMC Cancer 4:55. 2004
  10. pmc Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator
    Catherine Gondcaille
    Laboratoire de Biologie Moleculaire et Cellulaire, Faculte des Sciences Gabriel, 21000 Dijon, France
    J Cell Biol 169:93-104. 2005

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Peroxisomes during development and in distinct cell types
    Frank Roels
    Dept of Pathology, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium
    Adv Exp Med Biol 544:39-54. 2003
  2. ncbi request reprint Peroxisome mosaics
    Frank Roels
    Dept Pathology, Ghent University, Belgium
    Adv Exp Med Biol 544:97-106. 2003
  3. ncbi request reprint Why study regulation of genes in inherited disorders?
    Frank Roels
    Department of Pathology, Ghent University, University Hospital, De Pintelaan 185, 9000 Gent, Belgium
    Adv Exp Med Biol 544:1-8. 2003
  4. pmc Mitochondrial mosaics in the liver of 3 infants with mtDNA defects
    Frank Roels
    Department of Pathology, Ghent University Hospital, Block A, De Pintelaan 185, 9000 Gent, Belgium
    BMC Clin Pathol 9:4. 2009
    ..Tentative explanations for the mitochondrial mosaics are, in one patient, unequal partition of mutated mitochondria during mitoses, and in two others, an interaction between products of several genes required for mtDNA maintenance...
  5. ncbi request reprint Modified peroxisomes in primary hepatocyte cultures
    Marianne Depreter
    Ghent University, Dept Human Anatomy, Embryology, Histology, and Medical Physics, Godshuizenlaan 4, B 9000 Gent, Belgium
    Adv Exp Med Biol 544:255-64. 2003
  6. ncbi request reprint Regulation of peroxisomal genes by DHEA and vitamin D
    Marianne Depreter
    Department of Human Anatomy, Embryology, Histology and Medical Physics, Ghent University, B 9000 Gent, Belgium
    Adv Exp Med Biol 544:237-42. 2003
  7. ncbi request reprint Hepatocyte polarity and the peroxisomal compartment: a comparative study
    Marianne Depreter
    Department of Human Anatomy, Embryology, Histology, and Medical Physics, Ghent University, Godshuizenlaan 4, B 9000 Gent, Belgium
    Histochem J 34:139-51. 2002
    ..Distinct polarization characteristics do not necessarily change simultaneously, suggesting different regulatory mechanisms...
  8. ncbi request reprint Human peroxisomal disorders
    Marianne Depreter
    Ghent University, Department of Human Anatomy, Embryology, Histology and Medical Physics, Belgium
    Microsc Res Tech 61:203-23. 2003
    ..Finally, regulation of peroxisome expression during development and in cell cultures, and by physiological factors is discussed...
  9. pmc No evidence for involvement of SDHD in neuroblastoma pathogenesis
    Katleen De Preter
    Center for Medical Genetics, Ghent University Hospital, K5, De Pintelaan 185, B 9000 Ghent, Belgium
    BMC Cancer 4:55. 2004
    ..In this study, we sought for evidence for involvement of SDHD in neuroblastoma...
  10. pmc Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator
    Catherine Gondcaille
    Laboratoire de Biologie Moleculaire et Cellulaire, Faculte des Sciences Gabriel, 21000 Dijon, France
    J Cell Biol 169:93-104. 2005
    ..Thus, PBA is a nonclassical peroxisome proliferator inducing pleiotropic effects, including effects at the peroxisomal level mainly through HDAC inhibition...
  11. ncbi request reprint Resolution of the molecular defect in a patient with peroxisomal mosaicism in the liver
    Jeannette Gootjes
    Laboratory Genetic Metabolic Diseases and the Department of Pediatrics Emma Children s Hospital, Academic Medical Center, University of Amsterdam, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Adv Exp Med Biol 544:107-11. 2003
  12. pmc A PEX6-defective peroxisomal biogenesis disorder with severe phenotype in an infant, versus mild phenotype resembling Usher syndrome in the affected parents
    Annick Raas-Rothschild
    Department of Human Genetics, Hadassah University Hospital, Jerusalem 91120, Israel
    Am J Hum Genet 70:1062-8. 2002
    ..Because of considerable overlap between USH and milder PBD phenotypes, individuals suspected to have USH should be screened for peroxisomal dysfunction...
  13. ncbi request reprint Pharmacological induction of redundant genes for a therapy of X-ALD: phenylbutyrate and other compounds
    Maurice Bugaut
    Laboratory of Molecular and Cellular Biology, Faculty of Sciences Gabriel, University of Burgundy 21000 Dijon, France
    Adv Exp Med Biol 544:281-91. 2003
  14. ncbi request reprint Inhibition of cytokine production by the herbicide atrazine. Search for nuclear receptor targets
    Sabrina Devos
    Pharmacology Department FARC, Medical School, Vrije Universiteit Brussel, 103 Laarbeeklaan, B 1090 Brussel, Belgium
    Biochem Pharmacol 65:303-8. 2003
    ..Finally, no binding of atrazine to the AR was observed. In conclusion, the effects of atrazine-type herbicides most probably do not result from interaction with the above-mentioned nuclear receptors...
  15. ncbi request reprint Intra-familial clinical heterogeneity: absence of genotype-phenotype correlation in primary hyperoxaluria type 1 in Israel
    Yaacov Frishberg
    Division of Pediatric Nephrology, Shaare Zedek Medical Center, Jerusalem, Israel
    Am J Nephrol 25:269-75. 2005
    ..The aim of this study was to investigate possible relationships between a given genotype, the biochemical profile and the clinical phenotype...