Norbert H Lameire

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. ncbi request reprint Acute renal failure
    Norbert Lameire
    Renal Division, Department of Medicine, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    Lancet 365:417-30. 2005
  2. ncbi request reprint Acute renal failure in cancer patients
    Norbert H Lameire
    Ghent University Hospital, Ghent, Belgium
    Ann Med 37:13-25. 2005
  3. doi request reprint Acute kidney injury: an increasing global concern
    Norbert H Lameire
    Renal Division, University Hospital, Gent, Belgium
    Lancet 382:170-9. 2013
  4. doi request reprint Clinical practice guidelines: an important tool in improving dialysis quality
    Norbert Lameire
    University Hospital, Ghent, Belgium
    Contrib Nephrol 178:58-67. 2012
  5. doi request reprint Doubts on the long-term survival of peritoneal dialysis patients are no longer a medical barrier to home dialysis
    Norbert Lameire
    University Hospital, Ghent, Belgium
    Contrib Nephrol 178:47-52. 2012
  6. doi request reprint Electrolyte disturbances and acute kidney injury in patients with cancer
    Norbert Lameire
    Renal Division, University Hospital, Gent, Belgium
    Semin Nephrol 30:534-47. 2010
  7. ncbi request reprint Pathophysiology of acute renal failure in sepsis
    N Lameire
    Renal Division, University Hospital, Ghent, Belgium
    Acta Clin Belg 59:199-208. 2004
  8. ncbi request reprint What did we learn from animal models in peritoneal dialysis?
    Norbert Lameire
    Renal Division, University Hospital, Ghent, Belgium
    Contrib Nephrol 150:70-6. 2006
  9. ncbi request reprint Peritoneal dialysis in Europe: an analysis of its rise and fall
    Norbert Lameire
    Renal Division, University Hospital Ghent, Ghent, Belgium
    Blood Purif 24:107-14. 2006
  10. ncbi request reprint Hypervolemia in peritoneal dialysis patients
    Norbert Lameire
    Department of Internal Medicine, Renal Division, Ghent University Hospital, Ghent, Belgium
    J Nephrol 17:S58-66. 2004

Detail Information

Publications111 found, 100 shown here

  1. ncbi request reprint Acute renal failure
    Norbert Lameire
    Renal Division, Department of Medicine, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    Lancet 365:417-30. 2005
    ..Finally, some information on the influence of gene polymorphisms on the prognosis of acute renal failure is given...
  2. ncbi request reprint Acute renal failure in cancer patients
    Norbert H Lameire
    Ghent University Hospital, Ghent, Belgium
    Ann Med 37:13-25. 2005
    ..Ultimately, the key to managing ARF in cancer patients is to ensure that a multidisciplinary approach provides adequate assessment, appropriate preventative measures and early intervention...
  3. doi request reprint Acute kidney injury: an increasing global concern
    Norbert H Lameire
    Renal Division, University Hospital, Gent, Belgium
    Lancet 382:170-9. 2013
    ..Concerted international action encompassing many medical disciplines is needed to aid early recognition and management of acute kidney injury. ..
  4. doi request reprint Clinical practice guidelines: an important tool in improving dialysis quality
    Norbert Lameire
    University Hospital, Ghent, Belgium
    Contrib Nephrol 178:58-67. 2012
    ..However, there is, albeit largely indirect, evidence that adhering to CPGs is associated with improvement in dialysis care and even patient outcomes...
  5. doi request reprint Doubts on the long-term survival of peritoneal dialysis patients are no longer a medical barrier to home dialysis
    Norbert Lameire
    University Hospital, Ghent, Belgium
    Contrib Nephrol 178:47-52. 2012
    ..These recent survival results show that even over a long follow-up time, PD, at least in patients who are starting RRT in a planned way, has the same survival as patients starting on chronic hemodialysis...
  6. doi request reprint Electrolyte disturbances and acute kidney injury in patients with cancer
    Norbert Lameire
    Renal Division, University Hospital, Gent, Belgium
    Semin Nephrol 30:534-47. 2010
    ..Initiation and/or continuation of dialysis in the AKI cancer patient should be based on the general clinical condition and overall life expectancy and the personal patient expectations on quality of life after eventual recovery...
  7. ncbi request reprint Pathophysiology of acute renal failure in sepsis
    N Lameire
    Renal Division, University Hospital, Ghent, Belgium
    Acta Clin Belg 59:199-208. 2004
  8. ncbi request reprint What did we learn from animal models in peritoneal dialysis?
    Norbert Lameire
    Renal Division, University Hospital, Ghent, Belgium
    Contrib Nephrol 150:70-6. 2006
    ..More recently, genetically modified mice have been used as an important tool to investigate the molecular basis of peritoneal changes during dialysis and during acute peritonitis...
  9. ncbi request reprint Peritoneal dialysis in Europe: an analysis of its rise and fall
    Norbert Lameire
    Renal Division, University Hospital Ghent, Ghent, Belgium
    Blood Purif 24:107-14. 2006
    ..The overall structure of the health care in an individual country is to a large extent determining the use of a renal replacement therapy modality...
  10. ncbi request reprint Hypervolemia in peritoneal dialysis patients
    Norbert Lameire
    Department of Internal Medicine, Renal Division, Ghent University Hospital, Ghent, Belgium
    J Nephrol 17:S58-66. 2004
    ....
  11. ncbi request reprint A new initiative in nephrology: 'Kidney disease: improving global outcomes'
    Norbert Lameire
    Renal Division, University Hospital of Ghent, Ghent, Belgium
    Contrib Nephrol 149:90-9. 2005
    ....
  12. ncbi request reprint The pathophysiology of acute renal failure
    Norbert Lameire
    Renal Division, Department of Medicine, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    Crit Care Clin 21:197-210. 2005
    ..The postischemic kidney also shows a dramatic capacity for recovery. The molecular mechanisms and the effect of growth factors are also summarized...
  13. ncbi request reprint The anaemia of silent diabetic nephropathy-prevalence, physiopathology, and management
    N Lameire
    Renal Division, University Hospital, 185, De Pintelaan, 9000 Ghent
    Acta Clin Belg 58:159-68. 2003
  14. ncbi request reprint Volume control in peritoneal dialysis patients: role of new dialysis solutions
    Norbert Lameire
    Renal Division, University Hospital, Ghent, Belgium
    Blood Purif 22:44-54. 2004
    ..The solutions at normal pH containing either bicarbonate or a mixture of bicarbonate/lactate were clinically associated with less inflow pain...
  15. ncbi request reprint Decline in peritoneal dialysis publications--no reason for panic
    Norbert Lameire
    Perit Dial Int 27:149-52. 2007
  16. ncbi request reprint [Which are the therapeutic interventions allowing to ensure a protection of the renal function?]
    N Lameire
    Service de Nephrologie, Faculte de Medecine, hôpital universitaire Gand De Pintelaan, 185, 9000 Gent, Belgique
    Ann Fr Anesth Reanim 24:206-21. 2005
  17. pmc When to start dialysis in patients with acute kidney injury? When semantics and logic become entangled with expectations and beliefs
    Norbert Lameire
    Renal Division, University Hospital Gent, 185 De Pintelaan, 9000 Gent, Belgium
    Crit Care 15:171. 2011
    ..Initiating dialysis in AKI should be based on clinical criteria and not on serum creatinine or another serum/urine-based biomarker...
  18. doi request reprint How to use biomarkers efficiently in acute kidney injury
    Norbert H Lameire
    Renal Division, University Hospital, Ghent University, Ghent, Belgium
    Kidney Int 79:1047-50. 2011
    ..Unscrutinized use of these biomarkers may distract from adequate clinical evaluation and carries the risk of worse instead of better patient outcome...
  19. doi request reprint Epidemiology of peritoneal dialysis: a story of believers and nonbelievers
    Norbert Lameire
    Renal Division, University Hospital, 185 De Pintelaan, 9000 Gent, Belgium
    Nat Rev Nephrol 6:75-82. 2010
    ..To achieve these goals, academic and nonacademic training centers, which often consider peritoneal dialysis to be a low-level priority, must invest in research and training related to peritoneal dialysis...
  20. doi request reprint Did 20 years of technological innovations in hemodialysis contribute to better patient outcomes?
    Norbert Lameire
    Renal Division, Department of Medicine, University Hospital, 185, De Pintelaan, 9000 Gent Belgium
    Clin J Am Soc Nephrol 4:S30-40. 2009
    ....
  21. ncbi request reprint Nephrotoxicity of anticancer drugs--an underestimated problem?
    N Lameire
    Department of Medicine, Ghent University Hospital, Ghent, Belgium
    Acta Clin Belg 66:337-45. 2011
    ..The drugs discussed are cisplatin, methotrexate, ifosfamide, citumixab and panitumumab, mitocin C and gemcitabine and antiangiogenesis drugs...
  22. pmc Dose of dialysis in the intensive care unit: is the venom in the dose or in the clinical experience?
    Norbert Lameire
    Renal Division, University Hospital, De Pintelaan 185, 9000 Gent, Belgium
    Crit Care 13:155. 2009
    ..The last factor could explain why some single centre studies did find an impact of dialysis dose on the survival of these patients whereas multi-centre studies did not...
  23. doi request reprint What can we learn from registry data on peritoneal dialysis outcomes?
    Norbert Lameire
    Department of Medicine, University Hospital, Ghent, Belgium
    Contrib Nephrol 163:227-36. 2009
    ..These results support a policy of peritoneal dialysis as the first dialysis modality in a program of integral care...
  24. doi request reprint Acute renal problems in the critically ill cancer patient
    Norbert Lameire
    Renal Division of Nephrology, University Hospital Gent, Gent, Belgium
    Curr Opin Crit Care 14:635-46. 2008
    ....
  25. ncbi request reprint Intermittent hemodialysis for acute renal failure patients--an update
    Norbert Lameire
    Department of Medicine, University Hospital, De Pintelaan, Gent, Belgium
    Contrib Nephrol 144:255-63. 2004
  26. ncbi request reprint The changing epidemiology of acute renal failure
    Norbert Lameire
    Ghent University, Ghent, Belgium
    Nat Clin Pract Nephrol 2:364-77. 2006
    ....
  27. ncbi request reprint The kidney in oncology
    N Lameire
    University Hospital Ghent, 4K4 De Pintelaan 185, 9000 Gent, Belgium
    Acta Clin Belg 62:141-54. 2007
  28. ncbi request reprint Antibiotic administration in an animal model of chronic peritoneal dialysate exposure
    Siska Mortier
    Renal Unit, Department of Respiratory Diseases, University Hospital, Ghent, Belgium
    Perit Dial Int 23:331-8. 2003
    ..The present study examined the effects of prophylactic antibiotics on infection rate and peritoneal membrane function and structure in a rat model of chronic dialysate exposure...
  29. ncbi request reprint Long-term exposure to new peritoneal dialysis solutions: Effects on the peritoneal membrane
    Siska Mortier
    Renal Unit, University Hospital, Ghent, Belgium
    Kidney Int 66:1257-65. 2004
    ..Chronic exposure to peritoneal dialysis fluid (PDF) affects the peritoneum, but precise causative factors are incompletely understood. We examined the effects of standard and new PDF on peritoneal function and structure...
  30. ncbi request reprint Myofibroblast transdifferentiation of mesothelial cells is mediated by RAGE and contributes to peritoneal fibrosis in uraemia
    An S De Vriese
    The Renal Unit, University Hospital, Ghent, Belgium
    Nephrol Dial Transplant 21:2549-55. 2006
    ..We investigated whether antagonism of RAGE prevents uraemia-induced peritoneal fibrosis. In addition, we examined whether myofibroblast transdifferentiation of mesothelial cells contributes to peritoneal fibrosis in uraemia...
  31. ncbi request reprint Acute renal failure in patients with sepsis in a surgical ICU: predictive factors, incidence, comorbidity, and outcome
    Eric A J Hoste
    Intensive Care Unit and Renal Unit, Ghent University Hospital, Gent, Belgium
    J Am Soc Nephrol 14:1022-30. 2003
    ..This model allows initiating specific therapeutic measures earlier in the course of sepsis, hopefully resulting in a lower incidence of ARF and needi for RRT, thereby lowering mortality...
  32. ncbi request reprint Endothelium-derived hyperpolarizing factor-mediated renal vasodilatory response is impaired during acute and chronic hyperhomocysteinemia
    An S De Vriese
    Renal Unit, University Hospital, Gent, Belgium
    Circulation 109:2331-6. 2004
    ..The influence of hyperhomocysteinemia on EDHF is unknown. The present in vivo study evaluates the integrity of the EDHF pathway in the renal microcirculation of rats with acute and chronic hyperhomocysteinemia...
  33. ncbi request reprint Creatine supplementation does not decrease total plasma homocysteine in chronic hemodialysis patients
    Youri E C Taes
    Laboratory Clinical Chemistry, University Hospital Ghent, Belgium
    Kidney Int 66:2422-8. 2004
    ..The present study investigates the effects of creatine supplementation on tHcy in a vitamin-repleted chronic hemodialysis population...
  34. ncbi request reprint Sodium bicarbonate versus THAM in ICU patients with mild metabolic acidosis
    Eric A Hoste
    Intensive Care Unit, Ghent University Hospital, Gent, Belgium
    J Nephrol 18:303-7. 2005
    ..The aim of this study was to compare the efficacy and adverse effects of a single dose of sodium bicarbonate and THAM in intensive care unit (ICU) patients with mild metabolic acidosis...
  35. ncbi request reprint Health implications of antimicrobial resistance for patients with acute kidney injury and bloodstream infection
    Eric A J Hoste
    Intensive Care Department, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Infect Control Hosp Epidemiol 28:1107-10. 2007
    ..We found that infection with an antimicrobial-resistant organism did not adversely affect clinical outcome in this specific cohort, which already has a high mortality rate...
  36. ncbi request reprint The effects of heparin administration in an animal model of chronic peritoneal dialysate exposure
    An S De Vriese
    Renal Unit, University Hospital, Ghent, Belgium
    Perit Dial Int 22:566-72. 2002
    ..The use of a heparin-coated catheter in combination with antibiotics may be the optimal approach to obtaining peritoneal access in animal models of chronic dialysate exposure...
  37. ncbi request reprint Effects of conventional and new peritoneal dialysis fluids on leukocyte recruitment in the rat peritoneal membrane
    Siska Mortier
    Renal Division, University Hospital, OK 12, De Pintelaan 185, B 9000 Gent, Belgium
    J Am Soc Nephrol 14:1296-306. 2003
    ..Bicarbonate-buffered pH-neutral PDF with low GDP contents have fewer depressant effects and may therefore contribute to a better preservation of peritoneal host defense...
  38. ncbi request reprint Benefits of switching from a conventional to a low-GDP bicarbonate/lactate-buffered dialysis solution in a rat model
    Siska Mortier
    Renal Unit, University Hospital, Ghent, Belgium and Baxter R and D Europe, Nivelles, Belgium
    Kidney Int 67:1559-65. 2005
    ..We examined the potential of the low-GDP bicarbonate/lactate-buffered solution to reverse or reduce standard PDF-induced peritoneal alterations...
  39. ncbi request reprint Pathophysiological role of vascular endothelial growth factor in the remnant kidney
    Bieke F Schrijvers
    Department of Internal Medicine, Gent University Hospital, Gent, Belgium
    Nephron Exp Nephrol 101:e9-15. 2005
    ..On the other hand, progressive glomerulosclerosis and tubulo-interstitial fibrosis in the remnant kidney have been associated with loss of VEGF expression...
  40. ncbi request reprint Vascular hyporesponsiveness in the mesenteric artery of anaesthetized rats with cirrhosis and portal hypertension: an in-vivo study
    Isabelle O Colle
    Division of Hepato Gastroenterology, Department of Medicine, Ghent University Hospital, Belgium
    Eur J Gastroenterol Hepatol 16:139-45. 2004
    ..Cirrhosis is complicated by splanchnic vasodilation. Nitric oxide (NO) and prostacyclin contribute to this. Vascular hyporesponsiveness has been reported, but the underlying pathophysiological mechanisms are unclear...
  41. ncbi request reprint Studies on dialysate mixing in the Genius single-pass batch system for hemodialysis therapy
    Annemieke W Dhondt
    Renal Division, Department of Internal Medicine, Ghent University Hospital, Ghent, Belgium
    Kidney Int 63:1540-7. 2003
    ..In the present study, we investigated whether contamination of the unused dialysate with uremic solutes occurred and at which time point it began. Two different dialysate temperatures were compared...
  42. ncbi request reprint Creatine supplementation decreases homocysteine in an animal model of uremia
    Youri E C Taes
    Laboratory of Clinical Chemistry, University Hospital Ghent, Ghent, Belgium
    Kidney Int 64:1331-7. 2003
    ..Creatine supplementation down-regulates its endogenous synthesis and, thus, may reduce Hcy production. The present study investigates the effect of creatine supplementation on Hcy concentrations in an animal model of uremia...
  43. ncbi request reprint Inhibition of the interaction of AGE-RAGE prevents hyperglycemia-induced fibrosis of the peritoneal membrane
    An S De Vriese
    Renal Unit, University Hospital, Gent, Belgium
    J Am Soc Nephrol 14:2109-18. 2003
    ..Neoangiogenesis and the resultant loss of ultrafiltration capacity are mediated by different pathogenetic pathways...
  44. ncbi request reprint Assessment of renal function in recently admitted critically ill patients with normal serum creatinine
    Eric A J Hoste
    Intensive Care Unit, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium
    Nephrol Dial Transplant 20:747-53. 2005
    ....
  45. ncbi request reprint Effect of nosocomial bloodstream infection on the outcome of critically ill patients with acute renal failure treated with renal replacement therapy
    Eric A J Hoste
    Intensive Care Unit, Department of Public Health, Ghent University Hospital, Gent, Belgium
    J Am Soc Nephrol 15:454-62. 2004
    ..Nevertheless, the outcome was not influenced by the presence of bloodstream infection. The high mortality observed in ARF patients could therefore not be attributed to the higher incidence of bloodstream infection...
  46. ncbi request reprint Outcome in critically ill medical patients treated with renal replacement therapy for acute renal failure: comparison between patients with and those without haematological malignancies
    Dominique D Benoit
    Department of Internal Medicine, Intensive Care Medicine, Medical Intensive Care Unit, 12K12IB, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium
    Nephrol Dial Transplant 20:552-8. 2005
    ..The aim of this study was to compare the outcome between critically ill medical patients with and without haematological malignancies who received RRT for acute renal failure...
  47. ncbi request reprint Systemic and splanchnic haemodynamic effects of sildenafil in an in vivo animal model of cirrhosis support for a risk in cirrhotic patients
    Isabelle Colle
    Department of Medicine, Ghent University Hospital, Ghent, Belgium
    Liver Int 24:63-8. 2004
    ..The aim is to evaluate the effects of sildenafil on the systemic and splanchnic haemodynamics in an experimental model of cirrhosis...
  48. ncbi request reprint Effects of connexin-mimetic peptides on nitric oxide synthase- and cyclooxygenase-independent renal vasodilation
    An S De Vriese
    Renal Unit and the Department of Physiology, University Hospital, Gent, Belgium
    Kidney Int 61:177-85. 2002
    ..The present study examines the contribution of gap junctional communication to the EDHF-mediated responses in the rat renal microcirculation in vivo and addresses the physiological role of EDHF...
  49. ncbi request reprint The effects of peritoneal dialysis solutions on peritoneal host defense
    Siska Mortier
    Renal Unit, University Hospital, Ghent, Belgium
    Perit Dial Int 24:123-38. 2004
    ..Clinical studies, however, still need to demonstrate their superiority with respect to the incidence of PD-related peritonitis...
  50. ncbi request reprint Pathophysiology of ischaemic acute renal failure
    Norbert H Lameire
    Renal Division, Department of Medicine, University Hospital, De Pintelaan, 185, 9000 Ghent, Belgium
    Best Pract Res Clin Anaesthesiol 18:21-36. 2004
    ..Recent evidence points to the possibility that infiltration of the kidney with bone-marrow-derived stem cells contributes to the repair process. The molecular mechanisms and the effect of growth factors are summarized...
  51. ncbi request reprint Effect of dietary creatine on skeletal muscle myosin heavy chain isoform expression in an animal model of uremia
    Youri E C Taes
    Laboratory of Clinical Chemistry, University Hospital Ghent, Ghent, Belgium
    Nephron Exp Nephrol 96:e103-10. 2004
    ..Creatine is widely used as an ergogenic nutritional supplement in sportsmen. This study investigates the effect of creatine supplementation on MHC expression in the setting of uremic myopathy...
  52. ncbi request reprint Effects of new peritoneal dialysis solutions on leukocyte recruitment in the rat peritoneal membrane
    Siska Mortier
    Renal Division, University Hospital, Gent, Belgium
    Nephron Exp Nephrol 101:e139-45. 2005
    ....
  53. ncbi request reprint In vitro study of the potential role of guanidines in leukocyte functions related to atherogenesis and infection
    Griet L Glorieux
    Department of Internal Medicine, Renal Division, University Hospital, De Pintelaan, Ghent, Belgium
    Kidney Int 65:2184-92. 2004
    ..Uremic biologic fluids and several specific uremic retention solutes alter cell-mediated immune responses, as well as the interaction of calcitriol with the immune system...
  54. ncbi request reprint Creatine supplementation does not affect kidney function in an animal model with pre-existing renal failure
    Youri E C Taes
    Laboratory of Clinical Chemistry, Department of Internal Medicine, University Hospital Ghent, De Pintelaan 185, B 9000 Ghent, Belgium
    Nephrol Dial Transplant 18:258-64. 2003
    ..We investigated the effect of prolonged creatine ingestion on renal function in animals with normal kidney function or pre-existing kidney failure, respectively...
  55. ncbi request reprint Prevention and nondialytic treatment of acute renal failure
    Norbert H Lameire
    Renal Division, Department of Medicine, University Hospital De Pintelaan, Ghent, Belgium
    Curr Opin Crit Care 9:481-90. 2003
    ..Interventions to stimulate the recovery process of the damaged kidney with growth factors, although theoretically sound, have thus far not led to successful results...
  56. ncbi request reprint Recent concepts in the molecular biology of the peritoneal membrane - implications for more biocompatible dialysis solutions
    Siska Mortier
    Renal Division, University Hospital, De Pintelaan, Ghent, Belgium
    Blood Purif 21:14-23. 2003
    ..Ex vivo gene therapy involves harvesting peritoneum samples to isolate mesothelial cells that will be genetically modified before re-implantation into the peritoneal cavity...
  57. ncbi request reprint Differences in serum ionized and total magnesium values during chronic renal failure between nondiabetic and diabetic patients: a cross-sectional study
    Katy Dewitte
    Faculty of Pharmaceutical Sciences, Laboratory for Analytical Chemistry, Ghent University, Harelbekestraat 72, Ghent 9000, Belgium
    Diabetes Care 27:2503-5. 2004
  58. ncbi request reprint The impact of healthy start peritoneal dialysis on the evolution of residual renal function and nutrition parameters
    Wim Van Biesen
    Renal Division, University Hospital Gent, Gent, Belgium
    Adv Perit Dial 18:44-8. 2002
    ..No severe complications related to PD were seen. In view of the important impact of RRF and nutrition on patient outcome, our data may favor an early start of PD...
  59. ncbi request reprint Animal models in peritoneal dialysis research: a need for consensus
    Siska Mortier
    Renal Unit, University Hospital, Ghent, Belgium
    Perit Dial Int 25:16-24. 2005
    ..A collective effort to discuss the shortcomings and merits of the different experimental models may lead to a consensus on a standardized animal model of PD...
  60. ncbi request reprint Influence of dialysate on gastric emptying time in peritoneal dialysis patients
    VlemBrunoA Van
    Department of Internal Medicine, Ghent University Hospital, Belgium
    Perit Dial Int 22:32-8. 2002
    ..Gastroparesis might be, at least partially, a source of dyspeptic complaints in PD patients. The aim of the present study was to determine the influence of the presence and composition of dialysate on gastric emptying in PD patients...
  61. ncbi request reprint Long-term renal changes in the Goto-Kakizaki rat, a model of lean type 2 diabetes
    Bieke F Schrijvers
    Medical Research Laboratories, Institute of Experimental Clinical Research, Aarhus University Hospital, Denmark
    Nephrol Dial Transplant 19:1092-7. 2004
    ..We investigated long-term functional and structural renal changes in the Goto-Kakizaki rat to evaluate if this animal model resembles the changes observed in human diabetic kidney disease...
  62. ncbi request reprint Increased angiogenesis and permeability in the mesenteric microvasculature of rats with cirrhosis and portal hypertension: an in vivo study
    Anja M Geerts
    Department of Hepatology and Gastroenterology, Ghent University Hospital, Ghent, Belgium
    Liver Int 26:889-98. 2006
    ..The present study visualises in vivo structural changes (angiogenesis and vascular hyperpermeability) and examines the presence of VEGF and eNOS in the mesenteric microvasculature of animal models of PHT with and without cirrhosis...
  63. ncbi request reprint Is peritoneal dialysis associated with increased cardiovascular morbidity and mortality?
    Wim Van Biesen
    Department of Internal Medicine, University Hospital Ghent, Belgium
    Perit Dial Int 26:429-34. 2006
  64. ncbi request reprint Outcome in a post-cardiac surgery population with acute renal failure requiring dialysis: does age make a difference?
    Nele Van den Noortgate
    Division of Geriatric Medicine, Department of Internal Medicine, University Hospital Gent, Belgium
    Nephrol Dial Transplant 18:732-6. 2003
    ..The aim of our study was to evaluate the influence of age on and the risk factors for in-hospital mortality...
  65. ncbi request reprint Clamping of the dialysate outlet line in the Genius dialysis system does not alter dialysate flow or clearances
    Wim Van Biesen
    Renal Division, Department of Internal Medicine, University Hospital Ghent, 9000 Ghent, Belgium
    Nephrol Dial Transplant 21:1069-72. 2006
    ..This article analyses the impact of this intervention on the blood and dialysate flows and on the removal of retention products...
  66. ncbi request reprint The importance of standardization of creatinine in the implementation of guidelines and recommendations for CKD: implications for CKD management programmes
    Wim Van Biesen
    Department of Internal Medicine, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    Nephrol Dial Transplant 21:77-83. 2006
    ....
  67. ncbi request reprint The glomerular filtration rate in an apparently healthy population and its relation with cardiovascular mortality during 10 years
    Wim Van Biesen
    Department of Internal Medicine, Renal Division, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    Eur Heart J 28:478-83. 2007
    ..Also, the cut-off level of glomerular filtration rate (GFR) from which cardiovascular risk increases has not exactly been established. This study wants to address these questions...
  68. ncbi request reprint Decreased leukocyte recruitment in the mesenteric microcirculation of rats with cirrhosis is partially restored by treatment with peginterferon: an in vivo study
    Anja M Geerts
    Department of Hepatology and Gastroenterology, Ghent University Hospital, Belgium
    J Hepatol 46:804-15. 2007
    ..We investigated the effect of peginterferon-alpha2a (PegIFN-alpha(2a)) in vivo on the leukocyte recruitment in the mesenteric microcirculation of cirrhotic rats after lipopolysaccharide exposure...
  69. ncbi request reprint Belgium's mixed private/public health care system and its impact on the cost of end-stage renal disease
    Wim Van Biesen
    Renal Division, Department of Internal Medicine, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    Int J Health Care Finance Econ 7:133-48. 2007
    ..As dialysis costs increase, the ability to provide unrestricted access to dialysis treatment may be unsustainable. To aid in decision-making processes, nephrologists must be aware of financial and organizational issues...
  70. ncbi request reprint The personal dialysis capacity test is superior to the peritoneal equilibration test to discriminate inflammation as the cause of fast transport status in peritoneal dialysis patients
    Wim Van Biesen
    Department of Nephrology, University Hospital Ghent, De Pintelaan 185, Ghent 9000, Belgium
    Clin J Am Soc Nephrol 1:269-74. 2006
    ..The PET is not able to discriminate between FTS because of inflammation versus because of anatomic reasons, whereas the PDC test does...
  71. ncbi request reprint Residual renal function and volume status in peritoneal dialysis patients: a conflict of interest?
    Wim Van Biesen
    Renal Division, Department of Internal Medicine, University Hospital Ghent, Ghent, Belgium
    J Nephrol 21:299-304. 2008
    ..The paper will also point out some important practice points to avoid deterioration of residual renal function in PD patients, such as strict sodium diet and good glycemic control, that are also key to maintaining a good fluid balance...
  72. ncbi request reprint Delayed graft function in renal transplantation
    Patrick Peeters
    Renal Division, Department of Medicine, University Hospital, Ghent, Belgium
    Curr Opin Crit Care 10:489-98. 2004
    ....
  73. ncbi request reprint The dialytic management of acute renal failure in the elderly
    Nele Van de Noortgate
    Division of Geriatric Medicine, Department of Medicine, University Hospital, Ghent, Belgium
    Semin Dial 15:127-32. 2002
    ..It is the opinion of the authors that all dialysis strategies should be mastered and utilized for appropriate indications in elderly ARF patients...
  74. ncbi request reprint Initiation of dialysis--is the problem solved by NECOSAD?
    Norbert Lameire
    Renal Division, Department of Medicine, University Hospital, 185, De Pintelaan, 9000 Ghent, Belgium
    Nephrol Dial Transplant 17:1550-2. 2002
  75. doi request reprint A novel bio-assay increases the detection yield of microbiological impurity of dialysis fluid, in comparison to the LAL-test
    Griet Glorieux
    Department of Internal Medicine, Renal Division, Ghent University Hospital, Gent, Belgium
    Nephrol Dial Transplant 24:548-54. 2009
    ..Biological purity of dialysis water is considered as one of the primary conditions to deliver optimal haemodialysis...
  76. ncbi request reprint Improving salt balance in peritoneal dialysis patients
    Wim Van Biesen
    Renal Division, University Hospital Ghent, Belgium
    Perit Dial Int 25:S73-5. 2005
    ..It should always be considered that, due to sodium sieving over the ultrasmall pores, fluid and salt removal are not always concordant...
  77. ncbi request reprint Specific characteristics of peritoneal leucocyte populations during sterile peritonitis associated with icodextrin CAPD fluids
    Griet Glorieux
    Department of Internal Medicine, Renal Division, Ghent University Hospital, Ghent, Belgium
    Nephrol Dial Transplant 18:1648-53. 2003
    ....
  78. ncbi request reprint The use of low dose octreotide prophylaxis in pancreatic transplants with enteric drainage. Results of a prospective randomized single center trial
    Uwe J Hesse
    Department of Surgery, Ghent University Hospital, De Pintelaan, Ghent, Belgium
    Clin Transplant 19:299-303. 2005
    ....
  79. ncbi request reprint Dialysate partitioning in the Genius batch hemodialysis system: effect of temperature and solute concentration
    Annemieke Dhondt
    Renal Division, Department of Internal Medicine, Ghent University Hospital, Ghent, Belgium
    Kidney Int 67:2470-6. 2005
    ..The question is raised whether density differences cause this separation, and what the relative contributions of temperature and solute content are...
  80. ncbi request reprint The role of APD in the improvement of outcomes in an ESRD program
    Wim Van Biesen
    Renal Division, University Hospital Ghent, Ghent, Belgium
    Semin Dial 15:422-6. 2002
    ..In all cases, patients should have a free and informed choice...
  81. ncbi request reprint Kinetic behavior of urea is different from that of other water-soluble compounds: the case of the guanidino compounds
    Sunny Eloot
    Institute Biomedical Technology, Hydraulics Laboratory, Ghent University, Belgium
    Kidney Int 67:1566-75. 2005
    ..The question investigated in this study was whether other small water-soluble solutes, such as some guanidino compounds, show a kinetic behavior comparable or dissimilar to that of urea...
  82. ncbi request reprint In vitro evidence for immune activating effect of specific AGE structures retained in uremia
    Griet Glorieux
    Department of Internal Medicine, Renal Division, University Hospital, Ghent, Belgium
    Kidney Int 66:1873-80. 2004
    ..In the present study, the immunologic effect of specific AGE compounds, known to be retained in uremia, has been evaluated...
  83. ncbi request reprint Animal models in peritoneal dialysis: a story of kangaroos and ostriches
    Wim Van Biesen
    Renal Division, Department of Internal Medicine, University Hospital Ghent, Ghent, Belgium
    Perit Dial Int 26:571-3. 2006
  84. ncbi request reprint Relationship between fluid status and its management on acute renal failure (ARF) in intensive care unit (ICU) patients with sepsis: a prospective analysis
    Wim Van Biesen
    Renal Division, University Hospital, Ghent Belgium
    J Nephrol 18:54-60. 2005
    ..This study evaluates the relationship between fluid status and management and ARF development in septic patients...
  85. ncbi request reprint Efficacy of erythropoietin administration in the treatment of anemia immediately after renal transplantation
    Wim Van Biesen
    Department of Nephrology, University Hospital Ghent, Ghent, Belgium
    Transplantation 79:367-8. 2005
    ..There was no difference in the evolution of serum creatinine levels. In view of the cost, the use of RhuEpo in the posttransplantation period should be limited to high-risk patients...
  86. ncbi request reprint Serum cystatin C concentration compared with other markers of glomerular filtration rate in the old old
    Nele J Van Den Noortgate
    Department of Internal Medicine, Division of Gerontology and Geriatrics, University Hospital Ghent, Belgium
    J Am Geriatr Soc 50:1278-82. 2002
    ..To assess serum cystatin C, compared with other markers of renal function, as a marker of renal function in the old old (aged 85 and older)...
  87. ncbi request reprint Comparison of the radioiodinated serum albumin (RISA) dilution technique with direct volumetric measurements in animal models of peritoneal dialysis
    Wim Van Biesen
    Department of Internal Medicine, University Hospital Gent, Belgium
    Perit Dial Int 22:316-22. 2002
    ..The present study compares direct volume measurement with the Indicator dilution technique [radioiodinated serum albumin (RISA)] to determine the IPV over time curves In a rat model of PD...
  88. ncbi request reprint Exercise-induced myocardial ischemia is accompanied by increased serum creatine concentrations
    Youri E C Taes
    Laboratory Clinical Chemistry, Department of Internal Medicine, University Hospital Ghent, Belgium
    Clin Chem 49:684-6. 2003
  89. ncbi request reprint Survival and complications of indwelling venous catheters for permanent use in hemodialysis patients
    Willem Develter
    Renal Division, Department of Internal Medicine, University Hospital Ghent, Ghent, Belgium
    Artif Organs 29:399-405. 2005
    ..The risk factors influencing the survival of indwelling central vein catheters and their potential complications have not been assessed in depth and on a large scale...
  90. ncbi request reprint A randomized clinical trial with a 0.6% amino acid/ 1.4% glycerol peritoneal dialysis solution
    Wim Van Biesen
    Renal Division, University Hospital Ghent, Belgium
    Perit Dial Int 24:222-30. 2004
    ..Despite this achievement, there is a need for alternative osmotic agents.This randomized clinical trial analyzes 3-month's clinical experience with a mixture of 0.6% amino acids and 1.4% glycerol...
  91. ncbi request reprint The role of ultrasonography in the assessment of renal function in the elderly
    Nele Van den Noortgate
    Department of Internal Medicine, Division of Geriatric Medicine, Ghent University Hospital, Ghent, Belgium
    J Nephrol 16:658-62. 2003
    ..This study evaluated a possible correlation between renal function and kidney size measured by ultrasonography (US), and whether the latter helps estimate GFR in the elderly...
  92. ncbi request reprint Is folate a promising agent in the prevention and treatment of cardiovascular disease in patients with renal failure?
    An S De Vriese
    Renal Unit, University Hospital Gent, Gent, Belgium
    Kidney Int 61:1199-209. 2002
    ..Such trials are currently underway in patients with normal renal function at high risk for cardiovascular disease, and one trial has recently been initiated in stable renal transplant recipients...
  93. ncbi request reprint No early respiratory benefit with CVVHDF in patients with acute renal failure and acute lung injury
    Eric A J Hoste
    Intensive Care Unit, and Renal Division, Ghent University Hospital, Ghent, Belgium
    Nephrol Dial Transplant 17:2153-8. 2002
    ..Because haemofilter conditions should be comparable between patients, we opted for an evaluation of the effects during a 24-h period. Results of this trial can guide future studies in non-renal patients with acute lung injury...
  94. ncbi request reprint Contrast-induced nephropathy--prevention and risk reduction
    Norbert H Lameire
    Department of Internal Medicine, Renal Division, University of Gent, Gent, Belgium
    Nephrol Dial Transplant 21:i11-23. 2006
    ..This article will review the risk factors for the development of CIN and discuss practical strategies for its prevention in at-risk patients...
  95. ncbi request reprint Hemodynamic effects of peritoneal dialysis solutions on the rat peritoneal membrane: role of acidity, buffer choice, glucose concentration, and glucose degradation products
    Siska Mortier
    Renal Unit, University Hospital, Gent, Belgium
    J Am Soc Nephrol 13:480-9. 2002
    ..PDF with reduced GDP content induce no major hemodynamic effects and may thus have the potential to better preserve peritoneal vascular integrity...
  96. ncbi request reprint Management of the hemodialysis patient: a European perspective
    Norbert Lameire
    Renal Division, University Hospital, Ghent, Belgium
    Blood Purif 20:93-102. 2002
    ..No major differences in patient referral to the nephrologist, in residual renal function at the start of dialysis, nor in the dialysis dose based on Kt/V urea data were noted...
  97. ncbi request reprint The organization and interventions of the ISN Renal Disaster Relief Task Force
    Norbert Lameire
    Renal Division, Department of Medicine, University Hospital, 185 De Pintelaan, 9000 Ghent, Belgium
    Adv Ren Replace Ther 10:93-9. 2003
    ..The major intervention of the task force was at the occasion of the Marmara earthquake in Turkey in 1999. Additional more recent and minor interventions occurred in India and Algeria...
  98. ncbi request reprint Toxicity of free p-cresol: a prospective and cross-sectional analysis
    Rita De Smet
    University Hospital Gent, Department of Internal Medicine, Renal Division, Belgium
    Clin Chem 49:470-8. 2003
    ..It is conceivable, analogous with drugs, that the non-protein-bound fraction of p-cresol exerts toxicity. This aspect had never been evaluated, nor have the factors influencing the free fraction of p-cresol...
  99. ncbi request reprint Baseline renal function screening
    Norbert Lameire
    Department of Medicine, University Hospital, Ghent, Belgium
    Am J Cardiol 98:21K-26K. 2006
    ..In emergency situations, where the benefit of very early imaging outweighs the risk of waiting, the CIN Consensus Working Panel agreed that the procedure can be performed without assessment of renal function...
  100. doi request reprint Two-tier approach for the detection of alpha-galactosidase A deficiency in kidney transplant recipients
    Gert De Schoenmakere
    Department of Nephrology, Ghent University Hospital, Ghent, Belgium
    Nephrol Dial Transplant 23:4044-8. 2008
    ..Multi-organ involvement ensues in early adulthood and vital organs are affected: the kidneys, brain, heart. Several reports however suggest that AFD is underdiagnosed...
  101. ncbi request reprint Two-tier approach for the detection of alpha-galactosidase A deficiency in a predominantly female haemodialysis population
    Wim Terryn
    Department of Nephrology, Ghent University Hospital, Ghent, Belgium
    Nephrol Dial Transplant 23:294-300. 2008
    ..Untreated, this leads to precocious failure of vital organ function and death. As enzyme replacement therapy is available, it is of vital importance that affected individuals can be traced...