Jean Marc Kaufman

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. ncbi request reprint Teriparatide effects on vertebral fractures and bone mineral density in men with osteoporosis: treatment and discontinuation of therapy
    J M Kaufman
    Department of Endocrinology, Ghent University Hospital, 9K121E, De Pintelaan 185, Ghent, Belgium
    Osteoporos Int 16:510-6. 2005
  2. doi request reprint An evaluation of the Fracture Risk Assessment Tool (FRAX®) as an indicator of treatment efficacy: the effects of bazedoxifene and raloxifene on vertebral, nonvertebral, and all clinical fractures as a function of baseline fracture risk assessed by FRAX®
    J M Kaufman
    Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium
    Osteoporos Int 24:2561-9. 2013
  3. doi request reprint Beneficial and adverse effects of testosterone on the cardiovascular system in men
    Johannes B Ruige
    MD, PhD, Department of Endocrinology, Ghent University Hospital, De Pintelann 185, B9000 Gent, Belgium
    J Clin Endocrinol Metab 98:4300-10. 2013
  4. pmc Treatment of osteoporosis in men
    J M Kaufman
    Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, De Pintelaan 185, B9000 Gent, Belgium
    Bone 53:134-44. 2013
  5. doi request reprint Efficacy and safety of strontium ranelate in the treatment of osteoporosis in men
    J M Kaufman
    Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    J Clin Endocrinol Metab 98:592-601. 2013
  6. ncbi request reprint The decline of androgen levels in elderly men and its clinical and therapeutic implications
    Jean M Kaufman
    Department of Endocrinology, Ghent University Hospital, Ghent B 9000, Belgium
    Endocr Rev 26:833-76. 2005
  7. doi request reprint Osteoporosis in men
    Jean M Kaufman
    Ghent University Hospital, Department of Endocrinology, Gent, Belgium
    Best Pract Res Clin Endocrinol Metab 22:787-812. 2008
  8. ncbi request reprint Role of sex steroids in the regulation of bone metabolism in the adult skeleton
    J M Kaufman
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, B 9000 Gent, Belgium
    Ann Endocrinol (Paris) 67:119-22. 2006
  9. doi request reprint Sex hormone-binding globulin as an independent determinant of cortical bone status in men at the age of peak bone mass
    Griet Vanbillemont
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, 9K12IE, 9000 Ghent, Belgium
    J Clin Endocrinol Metab 95:1579-86. 2010
  10. doi request reprint Anthropometric and skeletal phenotype in men with idiopathic osteoporosis and their sons is consistent with deficient estrogen action during maturation
    Bruno Lapauw
    Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, B 9000 Ghent, Belgium
    J Clin Endocrinol Metab 94:4300-8. 2009

Detail Information

Publications68

  1. ncbi request reprint Teriparatide effects on vertebral fractures and bone mineral density in men with osteoporosis: treatment and discontinuation of therapy
    J M Kaufman
    Department of Endocrinology, Ghent University Hospital, 9K121E, De Pintelaan 185, Ghent, Belgium
    Osteoporos Int 16:510-6. 2005
    ..01). In conclusion, men who received teriparatide and who may have received follow-up antiresorptive therapy had a decreased risk of moderate and severe vertebral fractures...
  2. doi request reprint An evaluation of the Fracture Risk Assessment Tool (FRAX®) as an indicator of treatment efficacy: the effects of bazedoxifene and raloxifene on vertebral, nonvertebral, and all clinical fractures as a function of baseline fracture risk assessed by FRAX®
    J M Kaufman
    Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium
    Osteoporos Int 24:2561-9. 2013
    ..Relative risk of vertebral, nonvertebral, and all clinical fractures decreased with increasing probability of fracture for bazedoxifene (BZA) versus placebo but remained generally constant for raloxifene (RLX)...
  3. doi request reprint Beneficial and adverse effects of testosterone on the cardiovascular system in men
    Johannes B Ruige
    MD, PhD, Department of Endocrinology, Ghent University Hospital, De Pintelann 185, B9000 Gent, Belgium
    J Clin Endocrinol Metab 98:4300-10. 2013
    ..The widespread use of T therapy, particularly in aging males, necessitates knowledge of the relationship between T and the cardiovascular system...
  4. pmc Treatment of osteoporosis in men
    J M Kaufman
    Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, De Pintelaan 185, B9000 Gent, Belgium
    Bone 53:134-44. 2013
    ..Aspects of osteoporosis in men, such as screening and identification strategies, definitions of diagnosis and intervention thresholds, and treatment options (both approved and in the pipeline) are discussed...
  5. doi request reprint Efficacy and safety of strontium ranelate in the treatment of osteoporosis in men
    J M Kaufman
    Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    J Clin Endocrinol Metab 98:592-601. 2013
    ..Strontium ranelate reduces vertebral and nonvertebral fracture risk in postmenopausal osteoporosis...
  6. ncbi request reprint The decline of androgen levels in elderly men and its clinical and therapeutic implications
    Jean M Kaufman
    Department of Endocrinology, Ghent University Hospital, Ghent B 9000, Belgium
    Endocr Rev 26:833-76. 2005
    ....
  7. doi request reprint Osteoporosis in men
    Jean M Kaufman
    Ghent University Hospital, Department of Endocrinology, Gent, Belgium
    Best Pract Res Clin Endocrinol Metab 22:787-812. 2008
    ..e. bisphosphonates and teriparatide), is limited, so that they should be applied with discernment based on clinical judgement and careful estimation of fracture risk...
  8. ncbi request reprint Role of sex steroids in the regulation of bone metabolism in the adult skeleton
    J M Kaufman
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, B 9000 Gent, Belgium
    Ann Endocrinol (Paris) 67:119-22. 2006
  9. doi request reprint Sex hormone-binding globulin as an independent determinant of cortical bone status in men at the age of peak bone mass
    Griet Vanbillemont
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, 9K12IE, 9000 Ghent, Belgium
    J Clin Endocrinol Metab 95:1579-86. 2010
    ..A large fraction of these hormones are bound by SHBG, and previous studies have shown that SHBG could be a determinant of bone characteristics...
  10. doi request reprint Anthropometric and skeletal phenotype in men with idiopathic osteoporosis and their sons is consistent with deficient estrogen action during maturation
    Bruno Lapauw
    Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, B 9000 Ghent, Belgium
    J Clin Endocrinol Metab 94:4300-8. 2009
    ..Pathophysiology of deficient bone mass acquisition in male idiopathic osteoporosis (IO) remains poorly understood...
  11. doi request reprint Body composition and metabolic parameters are associated with variation in thyroid hormone levels among euthyroid young men
    Greet Roef
    Department of Endocrinology and Metabolic Bone Diseases, Ghent University Hospital, Belgium
    Eur J Endocrinol 167:719-26. 2012
    ..Therefore, we have investigated the relationship between thyroid hormone concentrations and body composition together with metabolic parameters in a population of healthy euthyroid men...
  12. doi request reprint Prevalence of low bone mass in relation to estrogen treatment and body composition in male-to-female transsexual persons
    Guy T'sjoen
    Department of Endocrinology, Ghent University Hospital, Belgium
    J Clin Densitom 12:306-13. 2009
    ..oral estrogens. Low bone mass is not uncommon in M --> F transsexual persons. Smaller bone size, and a strikingly lower muscle mass compared with men appear to underlie these findings...
  13. ncbi request reprint Are serum leptin and the Gln223Arg polymorphism of the leptin receptor determinants of bone homeostasis in elderly men?
    Patricia Crabbe
    Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Belgium
    Eur J Endocrinol 154:707-14. 2006
    ..This study assesses the contribution in elderly men of leptin and the Gln223Arg leptin receptor gene (LEPR) polymorphism to the variation in bone homeostasis, in relation to body composition and free estradiol as major confounders...
  14. doi request reprint Thyroid hormone status within the physiological range affects bone mass and density in healthy men at the age of peak bone mass
    Greet Roef
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Eur J Endocrinol 164:1027-34. 2011
    ..Apart from gonadal steroids and somatotropic hormones, thyroid hormones are known to affect bone maturation and homeostasis and are additional candidate determinants of adult bone mass...
  15. doi request reprint The relationship between changes in steps/day and health outcomes after a pedometer-based physical activity intervention with telephone support in type 2 diabetes patients
    Delfien Van Dyck
    Department of Movement and Sports Sciences, Faculty of Medicine and Health Sciences, Ghent University, Watersportlaan 2, 9000 Ghent, Belgium
    Health Educ Res 28:539-45. 2013
    ..Hence, although the intervention successfully increased steps/day, no direct effect on health outcomes was identified. However, an increase of ≥4000 steps/day seemed a threshold to have a positive impact on HbA1c...
  16. ncbi request reprint Vitamin D binding protein, bone status and body composition in community-dwelling elderly men
    Youri E C Taes
    Laboratory of Clinical Chemistry, Microbiology and Immunology 2P8, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Bone 38:701-7. 2006
    ..In conclusion, serum 1,25(OH)(2)-vitamin D concentrations are codetermined by DBP-phenotypes and DBP-concentrations. No major effect of DBP-polymorphism was demonstrated on BMD, bone turnover markers or body composition...
  17. doi request reprint Body composition, volumetric and areal bone parameters in male-to-female transsexual persons
    Bruno Lapauw
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Bone 43:1016-21. 2008
    ..Given the importance of sex steroids for developing and maintaining bone mass, bone health is a matter of concern in daily management of these patients...
  18. doi request reprint Birth weight in relation to sex steroid status and body composition in young healthy male siblings
    Griet Vanbillemont
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    J Clin Endocrinol Metab 95:1587-94. 2010
    ..From studies in children with intrauterine growth restriction, low birth weight has been associated with altered gonadotropin concentrations...
  19. doi request reprint Prevalent fractures are related to cortical bone geometry in young healthy men at age of peak bone mass
    Youri Taes
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    J Bone Miner Res 25:1433-40. 2010
    ..Moreover, the data suggest different mechanisms of childhood fractures and fractures during adult life...
  20. doi request reprint Heritability of blood concentrations of sex-steroids in relation to body composition in young adult male siblings
    Veerle Bogaert
    Department of Endocrinology, Ghent University Hospital, Belgium
    Clin Endocrinol (Oxf) 69:129-35. 2008
    ..This study investigates heritability estimates of sex steroid serum concentrations and body composition as well as the genetic and environmental components of their interrelation...
  21. pmc Serum dioxin-like activity is associated with reproductive parameters in young men from the general Flemish population
    Willem Dhooge
    Department of Endocrinology, University Hospital Ghent, Belgium
    Environ Health Perspect 114:1670-6. 2006
    ..In humans, fertility-related effects are less documented...
  22. doi request reprint Fat mass is negatively associated with cortical bone size in young healthy male siblings
    Youri E C Taes
    Department of Endocrinology, Ghent University Hospital, Belgium
    J Clin Endocrinol Metab 94:2325-31. 2009
    ..Whereas lean mass exerts a positive influence on bone size, the relationship between fat and bone remains unclear...
  23. doi request reprint Small effect of the androgen receptor gene GGN repeat polymorphism on serum testosterone levels in healthy men
    Veerle Bogaert
    Department of Endocrinology, 9 K12 I E, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Eur J Endocrinol 161:171-7. 2009
    ....
  24. ncbi request reprint Missense mutations in LRP5 are not a common cause of idiopathic osteoporosis in adult men
    Patricia Crabbe
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    J Bone Miner Res 20:1951-9. 2005
    ..We studied whether the LRP5 gene contributes to the clinical phenotype of IO in men. Mutation analysis in 66 IO men revealed a range of sequence variants, of which two missense variants were shown to be of functional relevance...
  25. doi request reprint Determinants of vitamin D status in young children: results from the Belgian arm of the IDEFICS (Identification and Prevention of Dietary- and Lifestyle-Induced Health Effects in Children and Infants) Study
    Isabelle Sioen
    Department of Public Health, Ghent University, UZ 2 Blok A, De Pintelaan 185, B 9000 Ghent, Belgium
    Public Health Nutr 15:1093-9. 2012
    ..To describe the vitamin D status of Belgian children and examine the influence of non-nutritional determinants, in particular of anthropometric variables...
  26. doi request reprint Sex hormone-binding globulin at the crossroad of body composition, somatotropic axis and insulin/glucose homeostasis in young healthy men
    Griet Vanbillemont
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    Clin Endocrinol (Oxf) 76:111-8. 2012
    ..We investigated to what extent different determinants contribute to the variation in SHBG levels in healthy young men...
  27. doi request reprint Early smoking is associated with peak bone mass and prevalent fractures in young, healthy men
    Youri Taes
    Department of Endocrinology, Ghent University Hospital, Belgium
    J Bone Miner Res 25:379-87. 2010
    ....
  28. ncbi request reprint Regional variations in semen quality of community-dwelling young men from Flanders are not paralleled by hormonal indices of testicular function
    Willem Dhooge
    Department of Endocrinology, Study Centre for Carcinogenesis and Primary Prevention of Cancer, University Hospital, Ghent, 185 De Pintelaan, B 9000 Ghent, Belgium
    J Androl 28:435-43. 2007
    ....
  29. doi request reprint Relationship between markers of body fat and calcaneal bone stiffness differs between preschool and primary school children: results from the IDEFICS baseline survey
    Isabelle Sioen
    Department of Public Health, Ghent University, Ghent, Belgium
    Calcif Tissue Int 91:276-85. 2012
    ..Fat-free mass may confound the association in primary school children but not in preschool children. Muscle mass may therefore be an important determinant of bone stiffness...
  30. pmc Glucose intolerance and the amount of visceral adipose tissue contribute to an increase in circulating triglyceride concentrations in Caucasian obese females
    Margot Berings
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    PLoS ONE 7:e45145. 2012
    ....
  31. pmc Sex steroids affect triglyceride handling, glucose-dependent insulinotropic polypeptide, and insulin sensitivity: a 1-week randomized clinical trial in healthy young men
    Bruno Lapauw
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    Diabetes Care 33:1831-3. 2010
    ..To evaluate metabolic effects of sex steroids in nonfasting and fasting conditions, independent from changes in body composition...
  32. doi request reprint Serum estradiol is associated with volumetric BMD and modulates the impact of physical activity on bone size at the age of peak bone mass: a study in healthy male siblings
    Bruno M Lapauw
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    J Bone Miner Res 24:1075-85. 2009
    ..E(2), but not T, levels are positively associated with vBMD and modulate the impact of physical activity on bone size at the tibia...
  33. pmc Thyroid hormone levels within reference range are associated with heart rate, cardiac structure, and function in middle-aged men and women
    Greet L Roef
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    Thyroid 23:947-54. 2013
    ..We investigated whether between-subject variation in thyroid hormone levels within the euthyroid range is also associated with heart rate and echocardiographic heart function and structure...
  34. doi request reprint ESR1 polymorphisms, daily hassles, anger expression, and depressive symptoms in adolescent boys and girls
    Hans Vermeersch
    Department of Sociology, University of Ghent, Korte Meer 5, 9000 Ghent, Belgium
    Horm Behav 63:447-53. 2013
    ..Additionally, ESR1 polymorphisms are related to anger expression styles in girls. Anger-related variables, however, did not mediate the relationship between ESR1 polymorphisms and depressive symptoms, in boys nor in girls...
  35. doi request reprint Polymorphisms of the SHBG gene contribute to the interindividual variation of sex steroid hormone blood levels in young, middle-aged and elderly men
    Griet Vanbillemont
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    Clin Endocrinol (Oxf) 70:303-10. 2009
    ..The aim of this study was to examine the influence of a missense mutation in exon 8 (Asp327Asn) and a (TAAAA)(n)-repeat in the promoter region of the SHBG gene, on SHBG and sex steroid serum concentrations in a population of healthy men...
  36. doi request reprint Testosterone, androgen receptor gene CAG repeat length, mood and behaviour in adolescent males
    Hans Vermeersch
    Department of Sociology, University of Ghent, Ghent, Belgium
    Eur J Endocrinol 163:319-28. 2010
    ....
  37. doi request reprint Combined gene and protein expression of hormone-sensitive lipase and adipose triglyceride lipase, mitochondrial content, and adipocyte size in subcutaneous and visceral adipose tissue of morbidly obese men
    Hélène De Naeyer
    Department of Abdominal Surgery, University Hospital, Ghent, Belgium
    Obes Facts 4:407-16. 2011
    ..To evaluate the role of lipolytic enzymes or mitochondria in lipotoxicity, we studied expression levels of genes and proteins involved in lipolysis and mitochondrial DNA (mtDNA) content...
  38. doi request reprint A genome-wide linkage scan for low spinal bone mineral density in a single extended family confirms linkage to 1p36.3
    Andy Willaert
    Department of Medical Genetics, Ghent University Hospital, Ghent, Belgium
    Eur J Hum Genet 16:970-6. 2008
    ..3. Although no specific disease causing mutation has yet been found, the delineation of a relatively small candidate region in a single extended family opens perspectives to identify a major gene for spinal BMD...
  39. ncbi request reprint Estrogen receptor signaling is an unstable feature of the gonadotropic LbetaT2 cell line
    Frank Eertmans
    Department of Endocrinology, 6K12IE, Ghent University Hospital, De Pintelaan, 185, B 9000 Ghent, Belgium
    Mol Cell Endocrinol 273:16-24. 2007
    ..Nevertheless, this cell line does not seem to be a suitable in vitro model for the study of estrogenic regulatory effects at the level of the pituitary gonadotrophs in view of the unstable nature of ER signaling in LbetaT2 cells...
  40. doi request reprint Estrogen-specific action on bone geometry and volumetric bone density: longitudinal observations in an adult with complete androgen insensitivity
    Youri Taes
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Bone 45:392-7. 2009
    ..In this report we describe changes in bone size and volumetric bone density in a complete androgen insensitive subject (CAIS) due to a mutation in the androgen receptor during 5 years of estrogen treatment...
  41. doi request reprint Triiodothyronine and free thyroxine levels are differentially associated with metabolic profile and adiposity-related cardiovascular risk markers in euthyroid middle-aged subjects
    Greet L Roef
    1 Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    Thyroid 24:223-31. 2014
    ....
  42. doi request reprint Hypoactive sexual desire in transsexual women: prevalence and association with testosterone levels
    Els Elaut
    Department of Sexology and Gender Problems, Ghent University Hospital, Belgium
    Eur J Endocrinol 158:393-9. 2008
    ..This study wishes to document the HSDD prevalence among transsexual women and the possible association to androgen levels...
  43. pmc Mediators of physical activity change in a behavioral modification program for type 2 diabetes patients
    Delfien Van Dyck
    Department of Movement and Sport Sciences, Ghent University, Watersportlaan 2, 9000 Ghent, Belgium
    Int J Behav Nutr Phys Act 8:105. 2011
    ..Our purpose was to examine mediation effects of changes in psychosocial variables on changes in physical activity in type 2 diabetes patients...
  44. ncbi request reprint Endogenous oestradiol and cardiovascular disease in healthy men: a systematic review and meta-analysis of prospective studies
    Guy Vandenplas
    Heart Center, Ghent University Hospital, Ghent, Belgium
    Heart 98:1478-82. 2012
    ..The literature provides no clear answer as to whether total oestradiol (E2) concentrations increase the risk of incident cardiovascular disease (CVD) in healthy men...
  45. doi request reprint Difference in receptor-binding contributes to difference in biological activity between the unique guinea pig GnRH and mammalian GnRH
    Chang Qing Gao
    Department of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium
    Neurosci Lett 507:124-6. 2012
    ....
  46. doi request reprint Genetic variations in the androgen receptor are associated with steroid concentrations and anthropometrics but not with muscle mass in healthy young men
    Hélène De Naeyer
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium Department of Movement and Sport Sciences, Ghent University, Ghent, Belgium
    PLoS ONE 9:e86235. 2014
    ..Therefore, we aim to investigate the relationship between genetic variations in the AR, circulating androgens and muscle mass and function in young healthy male siblings...
  47. ncbi request reprint Sex steroid level, androgen receptor polymorphism, and depressive symptoms in healthy elderly men
    Guy G T'Sjoen
    Department of Endocrinology, Unit for Osteoporosis and Metabolic Bone Diseases, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium
    J Am Geriatr Soc 53:636-42. 2005
    ....
  48. doi request reprint Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones
    Greet L Roef
    Department of Endocrinology, Ghent University Hospital, Belgium Electronic address
    Clin Chim Acta 425:227-32. 2013
    ..Several single nucleotide polymorphisms (SNPs) in these genes were reported to be associated with TH concentrations; however, results have been inconsistent...
  49. ncbi request reprint A novel mutation c.118delA in exon 1 of the androgen receptor gene resulting in complete androgen insensitivity syndrome within a large family
    Karel Decaestecker
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    Fertil Steril 89:1260.e3-7. 2008
    ..To confirm the clinical diagnosis of complete androgen insensitivity syndrome (CAIS) by molecular genetic testing and to offer carriership testing in female relatives should a disease-causing mutation be found...
  50. ncbi request reprint Influence of exogenous oestrogen or (anti-) androgen administration on soluble transferrin receptor in human plasma
    Guy G T'Sjoen
    Department of Endocrinology, University Hospital Ghent, De Pintelaan 185, 9000 Gent, Belgium
    J Endocrinol 186:61-7. 2005
    ..This assumption is supported by the positive correlation that was found to exist between plasma sTfR and IGF-I after the interventions (P<0.05)...
  51. ncbi request reprint Dual energy x-ray absorptiometry-based assessment of male patients using standardized bone density values and a national reference database
    Stefan Goemaere
    Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium
    J Clin Densitom 10:25-33. 2007
    ..The current data provide a basis to implement a nation-wide, uniform expression of BMD in male patients and allow harmonization of the BMD-based diagnosis and treatment of osteoporosis in men...
  52. doi request reprint Short- and long-term clinical skin effects of testosterone treatment in trans men
    Katrien Wierckx
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    J Sex Med 11:222-9. 2014
    ..Our knowledge concerning the effects of testosterone (T) therapy on the skin of trans men (female-to-male transsexuals) is scarce...
  53. doi request reprint Endogenous testosterone and cardiovascular disease in healthy men: a meta-analysis
    Johannes B Ruige
    Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
    Heart 97:870-5. 2011
    ..The literature provides no clear answer as to whether low endogenous testosterone increases risk of cardiovascular disease (CVD) in healthy men...
  54. doi request reprint Physical function measurements predict mortality in ambulatory older men
    Stefanie L De Buyser
    Department of Geriatrics, Ghent University Hospital, Ghent, Belgium
    Eur J Clin Invest 43:379-86. 2013
    ..To assess and compare the predictive value of physical function measurements (PFMs) for all-cause mortality in older men and to evaluate the Timed Up and Go test (TUG) as a predictor in subjects with underlying comorbidity...
  55. ncbi request reprint Estrogen receptor alpha (ERalpha) and insulin-like growth factor I receptor (IGF-IR) cross-talk in the gonadotropic alphaT3-1 cell line
    Frank Eertmans
    Department of Endocrinology, 6K12IE, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium
    J Cell Physiol 212:583-90. 2007
    ..In conclusion, our data indicate IGF-IR and ER interactions in the alphaT3-1 cell line, an in vitro model for the pituitary gonadotrophs, hereby suggesting a role of IGF-I in the regulation of gonadotropin synthesis and secretion...
  56. doi request reprint Sex steroid-induced changes in circulating monocyte chemoattractant protein-1 levels may contribute to metabolic dysfunction in obese men
    Johannes B Ruige
    Department of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium
    J Clin Endocrinol Metab 97:E1187-91. 2012
    ..Low testosterone accompanied by elevated estradiol associates with the development of metabolic dysfunction in men...
  57. doi request reprint Investigation of the potential association of vitamin D binding protein with lipoproteins
    Marijn M Speeckaert
    Department of Clinical Chemistry, Ghent University Hospital, Gent, Belgium
    Ann Clin Biochem 47:143-50. 2010
    ..We have previously reported a correlation between serum DBP and lipid parameters in a cystic fibrosis population. In the present study, the relationship between serum DBP, lipoprotein fractions and vitamin D is investigated...
  58. doi request reprint Estradiol, testosterone, differential association and aggressive and non-aggressive risk-taking in adolescent girls
    Hans Vermeersch
    Department of Sociology, University of Ghent, and Department of Endocrinology, University Hospital Ghent, Ghent 9000, Belgium
    Psychoneuroendocrinology 33:897-908. 2008
    ..In addition, significant interactions between differential association and FE2 were found indicating that the relationship between FE2 and NART and ART was particularly strong in girls with high levels of differential association...
  59. doi request reprint The role of testosterone in aggressive and non-aggressive risk-taking in adolescent boys
    Hans Vermeersch
    Department of Sociology, University of Ghent, Korte Meer 5, Ghent 9000, Belgium
    Horm Behav 53:463-71. 2008
    ..Our results indicate that hormone-related interests and predispositions may influence the development of affiliations with risk-taking peers, a factor which is crucial in understanding adolescent RT...
  60. ncbi request reprint Comparative assessment in young and elderly men of the gonadotropin response to aromatase inhibition
    Guy G T'Sjoen
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    J Clin Endocrinol Metab 90:5717-22. 2005
    ..Aging in men is associated with a decline in serum testosterone (T) levels...
  61. doi request reprint The effects of a pedometer-based behavioral modification program with telephone support on physical activity and sedentary behavior in type 2 diabetes patients
    Karlijn P De Greef
    Department of Movement and Sports Sciences, Ghent University, Ghent, Belgium
    Patient Educ Couns 84:275-9. 2011
    ..Effectiveness of a behavioral modification program on physical activity (PA) and sedentary behavior in diabetes patients...
  62. doi request reprint Further evaluation of the biological activity of the unique gonadotropin-releasing hormone peptide in the guinea pig brain
    Chang Qing Gao
    Department of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium
    Neurosci Lett 487:246-9. 2011
    ....
  63. ncbi request reprint Reproductive parameters of community-dwelling men from 2 regions in flanders are associated with the consumption of self-grown vegetables
    Willem Dhooge
    Department of Endocrinology, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium
    J Androl 28:836-46. 2007
    ..We could not exclude pesticide exposure by inappropriate application or other factors such as nutritional deficiency, physical activity, or stress as contributors to the observed regional differences...
  64. doi request reprint Development of a highly sensitive method for the quantification of estrone and estradiol in serum by liquid chromatography tandem mass spectrometry without derivatization
    Tom Fiers
    Ghent University Hospital, Department of Hormonology, De Pintelaan 185, 9000 Gent, Belgium
    J Chromatogr B Analyt Technol Biomed Life Sci 893:57-62. 2012
    ....
  65. ncbi request reprint Ability of peripheral bone assessments to predict areal bone mineral density at hip in community-dwelling elderly men
    Stefan Goemaere
    Unit for Osteoporosis and Metabolic Bone Diseases, Departments of Endocrinology and Rheumatology, Ghent University Hospital, Gent, Belgium
    J Clin Densitom 5:219-28. 2002
    ..It is concluded that peripheral measurements cannot be used as a substitute for hip DXA. However, they might be useful to guide patient referral for central DXA...
  66. doi request reprint Value and pitfalls in iodine fortification and supplementation in the 21st century
    Marijn M Speeckaert
    Department of Endocrinology, University Hospital Ghent, De Pintelaan 185, 9000 Gent, Belgium
    Br J Nutr 106:964-73. 2011
    ..Besides the multiple beneficial effects of supplementation, we present in this review a critical look at the possible side effects...
  67. pmc Cutaneous side effects of antiosteoporosis treatments
    Philippe Musette
    Department of Internal Medicine, Gent University Hospital, B 9000 Gent, Belgium
    Ther Adv Musculoskelet Dis 3:31-41. 2011
    ....
  68. ncbi request reprint Osteoporotic fracture treatment
    Nadine Hollevoet
    Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, De Pintelaan 185, B 9000 Gent, Belgium
    Acta Orthop Belg 77:441-7. 2011
    ..Low bone mineral density is not only associated with an increased fracture risk but also with more fracture displacement and reduction loss. The specific problems and main treatment options for these fragility fractures are reviewed...