Research Topics
| E A HosteSummaryAffiliation: Ghent University Country: Belgium Publications
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Detail Information
Publications
Epidemiology of acute kidney injuryEric A J Hoste
Intensive Care Unit, Ghent University Hospital, Ghent University, Gent, Belgium
Contrib Nephrol 165:1-8. 2010..AKI that occurs after the first week is mostly a consequence of sepsis or heart failure...
Clinical review: use of renal replacement therapies in special groups of ICU patientsEric A J Hoste
Department of Intensive Care Medicine, ICU, 2 K12C, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium
Crit Care 16:201. 2012..Exact and specific guidelines for RRT in these patients are not available for most clinical situations. In the present article we provide an update on the existing evidence...- Severe burn injury in Europe: a systematic review of the incidence, etiology, morbidity, and mortalityNele Brusselaers
Department of General Internal Medicine, Infectious Diseases and Psychosomatic Medicine, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium
Crit Care 14:R188. 2010..The aim of this study was to describe the European hospitalized population with severe burn injury, including the incidence, etiology, risk factors, mortality, and causes of death... - Acute kidney injury in burns: a story of volume and inflammationKirsten Colpaert
Intensive Care Unit, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium
Crit Care 12:192. 2008..Apart from the usual suspects - such as older age, severity of burn injury, sepsis and multiple organ dysfunction - volume overload probably has an important role in the pathogenesis of acute kidney injury... 
RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysisEric A J Hoste
The Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, Department of Critical Care Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA
Crit Care 10:R73. 2006....- A novel approach for prediction of tacrolimus blood concentration in liver transplantation patients in the intensive care unit through support vector regressionStijn Van Looy
Ghent University, Department of Information Technology, Gaston Crommenlaan 8, Ghent, Belgium
Crit Care 11:R83. 2007..Linear support vector regression (SVR) and nonlinear radial basis function (RBF) SVR are compared with multiple linear regression (MLR)... - Dynamics of C-reactive protein and white blood cell count in critically ill patients with nosocomial Gram positive vs. Gram negative bacteremia: a historical cohort studyDominique M Vandijck
Department of Intensive Care Medicine, Ghent University Hospital Ghent University, Faculty of Medicine and Health Sciences, De Pintelaan 185, Ghent, Belgium
BMC Infect Dis 7:106. 2007..Gram negative bacteremia (GNB), and to assess the potential benefit of serial measurements of both biomarkers in terms of early antimicrobial therapy initiation... 
Physiologic consequences of acute renal failure on the critically illEric A J Hoste
Intensive Care Unit, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium
Crit Care Clin 21:251-60. 2005..These factors contribute to a dysregulated inflammatory response and decreased immunity, and interfere with normal function of many organs. ACF may play an important role in the etiology of multiple organ dysfunction...- Sodium bicarbonate for prevention of contrast-induced acute kidney injury: a systematic review and meta-analysisEric A J Hoste
Intensive Care Unit, Ghent University Hospital, Gent, Belgium
Nephrol Dial Transplant 25:747-58. 2010..The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI... - Epidemiology of acute kidney injury: how big is the problem?Eric A J Hoste
Intensive Care Unit, Ghent University Hospital, Ghent, Belgium
Crit Care Med 36:S146-51. 2008..Acute kidney injury (AKI) is a complication that occurs frequently in hospitalized patients. In this article, we provide an overview of the literature on the epidemiology of AKI in hospitalized patients... - The epidemiology of cardiac surgery-associated acute kidney injuryE A Hoste
Intensive Care Unit, Ghent University Hospital, Gent, Belgium
Int J Artif Organs 31:158-65. 2008..To describe current knowledge on the epidemiology of cardiac surgery-associated acute kidney injury (CSA-AKI) and to formulate recommendations for clinical practice and a research agenda... - Health implications of antimicrobial resistance for patients with acute kidney injury and bloodstream infectionEric A J Hoste
Intensive Care Department, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
Infect Control Hosp Epidemiol 28:1107-10. 2007..We found that infection with an antimicrobial-resistant organism did not adversely affect clinical outcome in this specific cohort, which already has a high mortality rate... - Incidence, classification, and outcomes of acute kidney injuryEric A J Hoste
Intensive Care Unit, Ghent University Hospital, Ghent, Belgium
Contrib Nephrol 156:32-8. 2007..Recent data emphasized the importance of less severe impairment of kidney function, hence the terminology acute kidney injury (AKI) was introduced... - Epidemiology of contrast-associated acute kidney injury in ICU patients: a retrospective cohort analysisEric A J Hoste
Intensive Care Unit, ICU, 2K12 C, Ghent University Hospital, Ghent University, De Pintelaan 185, 9000, Ghent, Belgium
Intensive Care Med 37:1921-31. 2011..Data on this in ICU patients are scarce. The aim of this study was therefore to evaluate the epidemiology and short- and long-term outcomes of CA-AKI in ICU patients... - Clinical consequences of acute kidney injuryEric A J Hoste
ICU Ghent University Hospital, Ghent University, Ghent, Belgium
Contrib Nephrol 174:56-64. 2011..Finally, inadequate antimicrobial dosing probably plays an important role in the morbidity and mortality of AKI. These findings have led to a paradigm shift: patients die because of AKI rather than with AKI... - Acute renal failure in patients with sepsis in a surgical ICU: predictive factors, incidence, comorbidity, and outcomeEric A J Hoste
Intensive Care Unit and Renal Unit, Ghent University Hospital, Gent, Belgium
J Am Soc Nephrol 14:1022-30. 2003..This model allows initiating specific therapeutic measures earlier in the course of sepsis, hopefully resulting in a lower incidence of ARF and needi for RRT, thereby lowering mortality... - Costs and length of stay associated with antimicrobial resistance in acute kidney injury patients with bloodstream infectionD M Vandijck
Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, Department of Intensive Care Medicine, Belgium
Acta Clin Belg 63:31-8. 2008..This study aimed to assess whether microbial susceptibility patterns affect costs and LOS in a well-defined cohort of ICU patients with AKI undergoing renal replacement therapy (RRT) who developed nosocomial BSI... - Assessment of renal function in recently admitted critically ill patients with normal serum creatinineEric A J Hoste
Intensive Care Unit, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium
Nephrol Dial Transplant 20:747-53. 2005.... - Blood stream infections of abdominal origin in the intensive care unit: characteristics and determinants of deathJan J De Waele
Intensive Care Unit, Ghent University Hospital, Ghent, Belgium
Surg Infect (Larchmt) 9:171-7. 2008..Blood stream infections (BSI) of abdominal origin are associated with a high mortality rate. We hypothesized that both patient and microbiological factors determine death in critically ill patients who develop such infections... - Acute effects of upright position on gas exchange in patients with acute respiratory distress syndromeEric A J Hoste
Intensive Care Unit, Ghent University Hospital, Ghent, Belgium
J Intensive Care Med 20:43-9. 2005..Upright positioning of patients with ARDS, a relatively simple maneuver, resulted in an improvement of gas exchange and was tolerated hemodynamically relatively well during a 12-hour observation period... - Effect of nosocomial bloodstream infection on the outcome of critically ill patients with acute renal failure treated with renal replacement therapyEric A J Hoste
Intensive Care Unit, Department of Public Health, Ghent University Hospital, Gent, Belgium
J Am Soc Nephrol 15:454-62. 2004..Nevertheless, the outcome was not influenced by the presence of bloodstream infection. The high mortality observed in ARF patients could therefore not be attributed to the higher incidence of bloodstream infection... - Relative adrenal insufficiency in patients with severe acute pancreatitisJan J De Waele
Intensive Care Unit 1K12 C, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
Intensive Care Med 33:1754-60. 2007..This study aimed to analyse the incidence of relative adrenal insufficiency (RAI) in these patients, to identify factors associated with RAI and to describe how adrenal responsiveness affects outcome... - Acute kidney injury: epidemiology and diagnostic criteriaEric A J Hoste
Intensive Care Unit, Ghent University Hospital, Ghent, Belgium
Curr Opin Crit Care 12:531-7. 2006..SUMMARY: Small changes in kidney function in hospitalized patients are important and impact on outcome. RIFLE criteria provide a uniform definition of acute kidney injury and are increasingly used in literature... - Epidemiology of infection in critically ill patients with acute renal failureEmmelie Reynvoet
Department of Medicine and Health Sciences, Ghent University, Ghent, Belgium
Crit Care Med 37:2203-9. 2009..Therefore, we investigated the occurrence of infection in a cohort of critically ill patients with ARF treated with renal replacement therapy (RRT). In addition, we assessed whether this infection worsened outcome... - No early respiratory benefit with CVVHDF in patients with acute renal failure and acute lung injuryEric A J Hoste
Intensive Care Unit, and Renal Division, Ghent University Hospital, Ghent, Belgium
Nephrol Dial Transplant 17:2153-8. 2002..Because haemofilter conditions should be comparable between patients, we opted for an evaluation of the effects during a 24-h period. Results of this trial can guide future studies in non-renal patients with acute lung injury... - Outcome and changes over time in survival following severe burns from 1985 to 2004Nele Brusselaers
Intensive Care Department, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
Intensive Care Med 31:1648-53. 2005..Taking into account that our patients over the past 20 years have been progressively less extensively burned and hence have a lesser at risk for death, survival following severe burns has continued to improve... - Variation in critical care services across North America and Western EuropeHannah Wunsch
Department of Anesthesiology, Columbia University, New York, NY, USA
Crit Care Med 36:2787-93, e1-9. 2008..Yet, little is known regarding international variation in critical care services. We sought to understand differences in critical care delivery by comparing data on the distribution of services in eight countries... - Acute kidney injury: epidemiology and assessmentJohn A Kellum
Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Scand J Clin Lab Invest Suppl 241:6-11. 2008..Patients with AKI who are treated with RRT, still have a mortality of 50-60 %. Of surviving patients, 5-20 % remain dialysis-dependent at hospital discharge... - RIFLE criteria provide robust assessment of kidney dysfunction and correlate with hospital mortalityEric A J Hoste
Crit Care Med 34:2016-7. 2006 - The diagnosis of relative adrenal insufficiency: the long and winding roadJan J De Waele
Am J Respir Crit Care Med 176:945; author reply 945-6. 2007