Herman W Favoreel

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. ncbi request reprint Cell type-specific resistance of trigeminal ganglion neurons towards apoptotic stimuli
    Kristin Geenen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Microbiol 113:223-9. 2006
  2. pmc Alpha-herpesvirus glycoprotein D interaction with sensory neurons triggers formation of varicosities that serve as virus exit sites
    Nick De Regge
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium
    J Cell Biol 174:267-75. 2006
  3. pmc Development and use of a polarized equine upper respiratory tract mucosal explant system to study the early phase of pathogenesis of a European strain of equine arteritis virus
    Sabrina Vairo
    Laboratory of Virology, Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke B 9820, Belgium
    Vet Res 44:22. 2013
  4. pmc Germination of Aspergillus fumigatus inside avian respiratory macrophages is associated with cytotoxicity
    Lieven Van Waeyenberghe
    The Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820, Merelbeke, Belgium
    Vet Res 43:32. 2012
  5. pmc Susceptibility of in vitro produced hatched bovine blastocysts to infection with bluetongue virus serotype 8
    Leen Vandaele
    Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Res 42:14. 2011
  6. pmc Quantification of fibronectin 1 (FN1) splice variants, including two novel ones, and analysis of integrins as candidate FN1 receptors in bovine preimplantation embryos
    Karen Goossens
    Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Heidestraat 19, 9820 Merelbeke, Belgium
    BMC Dev Biol 9:1. 2009
  7. ncbi request reprint Actin and Rho GTPases in herpesvirus biology
    Herman W Favoreel
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium
    Trends Microbiol 15:426-33. 2007
  8. ncbi request reprint The why's of Y-based motifs in alphaherpesvirus envelope proteins
    Herman W Favoreel
    Laboratory of Virology and Laboratory of Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virus Res 117:202-8. 2006
  9. pmc Copatching and lipid raft association of different viral glycoproteins expressed on the surfaces of pseudorabies virus-infected cells
    Herman W Favoreel
    Laboratory of Virology Laboratory of Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Virol 78:5279-87. 2004
  10. ncbi request reprint Alphaherpesvirus use and misuse of cellular actin and cholesterol
    Herman W Favoreel
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Microbiol 143:2-7. 2010

Collaborators

Detail Information

Publications49

  1. ncbi request reprint Cell type-specific resistance of trigeminal ganglion neurons towards apoptotic stimuli
    Kristin Geenen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Microbiol 113:223-9. 2006
    ..In conclusion, sensory TG neurons may contain a cell type-specific capacity to withstand different apoptotic assaults, including infection with an alphaherpesvirus...
  2. pmc Alpha-herpesvirus glycoprotein D interaction with sensory neurons triggers formation of varicosities that serve as virus exit sites
    Nick De Regge
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium
    J Cell Biol 174:267-75. 2006
    ....
  3. pmc Development and use of a polarized equine upper respiratory tract mucosal explant system to study the early phase of pathogenesis of a European strain of equine arteritis virus
    Sabrina Vairo
    Laboratory of Virology, Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke B 9820, Belgium
    Vet Res 44:22. 2013
    ..This study validates the usefulness of a polarized mucosal explant system and shows that CD172a+ myeloid cells and CD3+ T lymphocytes represent important EAV-target cells in the respiratory mucosa...
  4. pmc Germination of Aspergillus fumigatus inside avian respiratory macrophages is associated with cytotoxicity
    Lieven Van Waeyenberghe
    The Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820, Merelbeke, Belgium
    Vet Res 43:32. 2012
    ..fumigatus conidia exceeds the macrophage killing capacity, leading to intracellular germination and colonization of the respiratory tract...
  5. pmc Susceptibility of in vitro produced hatched bovine blastocysts to infection with bluetongue virus serotype 8
    Leen Vandaele
    Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Res 42:14. 2011
    ..We conclude from this in vitro study that some of the reproductive problems that are reported when cattle herds are infected with BTV-8 may be attributed to direct infection of blastocysts and other early-stage embryos in utero...
  6. pmc Quantification of fibronectin 1 (FN1) splice variants, including two novel ones, and analysis of integrins as candidate FN1 receptors in bovine preimplantation embryos
    Karen Goossens
    Department of Nutrition, Genetics and Ethology, Faculty of Veterinary Medicine, Ghent University, Heidestraat 19, 9820 Merelbeke, Belgium
    BMC Dev Biol 9:1. 2009
    ....
  7. ncbi request reprint Actin and Rho GTPases in herpesvirus biology
    Herman W Favoreel
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium
    Trends Microbiol 15:426-33. 2007
    ..Unraveling these often fascinating interactions might also provide additional insights into sometimes poorly known aspects of actin biology (e.g. its role in the nucleus) and in the development of novel antiviral therapies...
  8. ncbi request reprint The why's of Y-based motifs in alphaherpesvirus envelope proteins
    Herman W Favoreel
    Laboratory of Virology and Laboratory of Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virus Res 117:202-8. 2006
    ..The current minireview will discuss the functions associated with these tyrosine-based motifs in alphaherpesvirus envelope proteins...
  9. pmc Copatching and lipid raft association of different viral glycoproteins expressed on the surfaces of pseudorabies virus-infected cells
    Herman W Favoreel
    Laboratory of Virology Laboratory of Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Virol 78:5279-87. 2004
    ..Therefore, we hypothesize that efficient gE-mediated capping of antibody-antigen patches may require the lipid raft-associated signal transduction machinery...
  10. ncbi request reprint Alphaherpesvirus use and misuse of cellular actin and cholesterol
    Herman W Favoreel
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Microbiol 143:2-7. 2010
    ....
  11. pmc Cytoskeletal rearrangements and cell extensions induced by the US3 kinase of an alphaherpesvirus are associated with enhanced spread
    Herman W Favoreel
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium
    Proc Natl Acad Sci U S A 102:8990-5. 2005
    ....
  12. ncbi request reprint Herpesvirus interference with virus-specific antibodies: bridging antibodies, internalizing antibodies, and hiding from antibodies
    Herman W Favoreel
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Microbiol 113:257-63. 2006
    ....
  13. ncbi request reprint Brn-3a suppresses pseudorabies virus-induced cell death in sensory neurons
    Kristin Geenen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Gen Virol 88:743-7. 2007
    ....
  14. ncbi request reprint A point mutation in the putative ATP binding site of the pseudorabies virus US3 protein kinase prevents Bad phosphorylation and cell survival following apoptosis induction
    Matthias Deruelle
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virus Res 128:65-70. 2007
    ..These results suggest that the kinase activity of the US3 protein of PRV is crucial to protect cells from apoptotic cell death during infection, at least partly by leading to phosphorylation of the pro-apoptotic Bad protein...
  15. ncbi request reprint Higher resistance of porcine trigeminal ganglion neurons towards pseudorabies virus-induced cell death compared with other porcine cell types in vitro
    Kristin Geenen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Gen Virol 86:1251-60. 2005
    ....
  16. doi request reprint Suppression of NK cells and regulatory T lymphocytes in cats naturally infected with feline infectious peritonitis virus
    Ben L Vermeulen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Microbiol 164:46-59. 2013
    ..However, these results will also open possibilities for new therapies targeting specifically NK cells and Tregs to enhance their numbers and/or functionality during FIPV infection...
  17. pmc Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages
    Peter L Delputte
    Laboratory of Virology, Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    PLoS ONE 6:e16827. 2011
    ....
  18. pmc Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases
    Celine Van den Broeke
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Proc Natl Acad Sci U S A 106:8707-12. 2009
    ..In addition, US3 was found to bind and phosphorylate group A PAKs. Lack of group A PAKs in MEFs was correlated with inefficient virus spread. Thus, US3 induces its effect on the actin cytoskeleton via group A PAKs...
  19. ncbi request reprint The kinase activity of pseudorabies virus US3 is required for modulation of the actin cytoskeleton
    Celine Van den Broeke
    Department of Virology, Parasitology, and Immunology, Ghent University, Belgium
    Virology 385:155-60. 2009
    ..These data show that different viruses have developed independent mechanisms to induce very similar actin rearrangements...
  20. pmc Pseudorabies virus glycoprotein gD contains a functional endocytosis motif that acts in concert with an endocytosis motif in gB to drive internalization of antibody-antigen complexes from the surface of infected monocytes
    Jolanta Ficinska
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Virol 79:7248-54. 2005
    ....
  21. pmc A tyrosine-based motif in the cytoplasmic tail of pseudorabies virus glycoprotein B is important for both antibody-induced internalization of viral glycoproteins and efficient cell-to-cell spread
    Herman W Favoreel
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Virol 76:6845-51. 2002
    ..Mutating the dileucine motif in the gB tail led to an increased cell-to-cell spread of the virus and the formation of large syncytia...
  22. ncbi request reprint Antibody-induced internalization of viral glycoproteins and gE-gI Fc receptor activity protect pseudorabies virus-infected monocytes from efficient complement-mediated lysis
    Gerlinde R Van De Walle
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    J Gen Virol 84:939-48. 2003
    ....
  23. ncbi request reprint Pseudorabies virus (PRV)-specific antibodies suppress intracellular viral protein levels in PRV-infected monocytes
    Herman W Favoreel
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke 9820, Belgium
    J Gen Virol 84:2969-73. 2003
    ..These data suggest that PRV-specific antibodies suppress viral protein levels in infected monocytes, perhaps helping the virus to persist and reach internal organs in vaccinated animals...
  24. pmc Internalization of pseudorabies virus glycoprotein B is mediated by an interaction between the YQRL motif in its cytoplasmic domain and the clathrin-associated AP-2 adaptor complex
    Geert Van Minnebruggen
    Laboratories of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Virol 78:8852-9. 2004
    ..e., PRV gB, a specific amino acid sequence in the cytoplasmic tail of the protein interacts with AP-2 and may constitute a common AP-2-mediated mechanism of internalization of alphaherpesvirus envelope proteins...
  25. doi request reprint An emerging role for p21-activated kinases (Paks) in viral infections
    Celine Van den Broeke
    Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Trends Cell Biol 20:160-9. 2010
    ..Careful assessment of the potential role of Paks in antiviral immunity will be pivotal to evaluate thoroughly the potential of agents that inhibit Pak as a new class of anti-viral therapeutics...
  26. ncbi request reprint Tyrosine phosphorylation and lipid raft association of pseudorabies virus glycoprotein E during antibody-mediated capping
    Ann S Desplanques
    Department of Virology, Parasitology and Immunology, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virology 362:60-6. 2007
    ..These results provide evidence that gE-mediated capping is a viral mimicry of immunoreceptor capping...
  27. ncbi request reprint Transmission of pseudorabies virus from immune-masked blood monocytes to endothelial cells
    Gerlinde R Van De Walle
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    J Gen Virol 84:629-37. 2003
    ..In conclusion, immune-masked PRV-infected monocytes can adhere and subsequently transmit virus to endothelial cells in the presence of PRV-neutralizing antibodies...
  28. doi request reprint Pseudorabies virus US3-mediated inhibition of apoptosis does not affect infectious virus production
    Matthias J Deruelle
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Gen Virol 91:1127-32. 2010
    ..However, inhibition of apoptosis did not affect US3null or WT PRV extracellular or cell-associated virus titres, nor did it restore the small plaque phenotype of US3null PRV...
  29. ncbi request reprint Pseudorabies virus US3- and UL49.5-dependent and -independent downregulation of MHC I cell surface expression in different cell types
    Matthias J Deruelle
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virology 395:172-81. 2009
    ..5. In conclusion, we show that the mechanism(s) of PRV-mediated cell surface MHC I downregulation are cell-type-dependent, with variable roles for US3, UL49.5, and additional, yet unidentified early viral proteins...
  30. doi request reprint Cholesterol depletion affects infectivity and stability of pseudorabies virus
    Ann S Desplanques
    Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Virus Res 152:180-3. 2010
    ..Hence, cholesterol is important for pseudorabies virus infectivity and stability...
  31. doi request reprint Plasma membrane cholesterol is required for efficient pseudorabies virus entry
    Ann S Desplanques
    Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Virology 376:339-45. 2008
    ..A significant fraction of PRV virions appears to localize juxtaposed to GM1, a lipid raft marker, during entry. Together, these data indicate that cholesterol and possibly cholesterol-rich lipid rafts may be important during PRV entry...
  32. doi request reprint Diverse microbial interactions with the basement membrane barrier
    Lennert Steukers
    Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Trends Microbiol 20:147-55. 2012
    ..g. leukocytes and dendritic cells) and oncogenic microorganisms might even trigger metastatic processes in epithelial cells to penetrate the underlying BM...
  33. pmc Pseudorabies virus US3 protein kinase mediates actin stress fiber breakdown
    Geert Van Minnebruggen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium
    J Virol 77:9074-80. 2003
    ..Further, by transfection assays, we showed that PRV US3 itself, in the absence of other viral proteins, is able to trigger actin stress fiber breakdown when it is localized in sufficient amounts in the nucleus...
  34. ncbi request reprint Antibody-induced internalization of viral glycoproteins in pseudorabies virus-infected monocytes and role of the cytoskeleton: a confocal study
    Gerlinde R Van De Walle
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium
    Vet Microbiol 86:51-7. 2002
    ..It can be stated that clathrin, dynein and microtubules, important components during physiological endocytosis, are also of importance during the antibody-induced internalization of viral glycoproteins...
  35. pmc A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa
    Sarah Glorieux
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Res 42:58. 2011
    ..9% reduction in plaque depth underneath the basement membrane. These data reveal a role of a trypsin-like serine protease in PRV penetration of the basement membrane...
  36. pmc Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa
    Sarah Glorieux
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    PLoS ONE 6:e22160. 2011
    ..Remarkably, interactions of herpesviruses with human mucosa, the locus of infection, remain poorly understood and the underlying mechanisms in stromal infection remain controversial...
  37. ncbi request reprint The pseudorabies virus US3 protein kinase possesses anti-apoptotic activity that protects cells from apoptosis during infection and after treatment with sorbitol or staurosporine
    Kristin Geenen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisbury laan 133, 9820 Merelbeke, East Flanders, Belgium
    Virology 331:144-50. 2005
    ....
  38. pmc Alphaherpesviral US3 kinase induces cofilin dephosphorylation to reorganize the actin cytoskeleton
    Thary Jacob
    Laboratory of Immunology, Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    J Virol 87:4121-6. 2013
    ..In conclusion, the US3 kinase of PRV leads to activation (dephosphorylation) of cofilin, and cofilin contributes to US3-mediated actin rearrangements...
  39. pmc Actin' up: herpesvirus interactions with Rho GTPase signaling
    Celine Van den Broeke
    Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium
    Viruses 3:278-92. 2011
    ..The current review gives an overview of both general and individual interactions of herpesviruses with Rho GTPase signaling...
  40. ncbi request reprint Immune escape of equine herpesvirus 1 and other herpesviruses of veterinary importance
    Karen M van der Meulen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Immunol Immunopathol 111:31-40. 2006
    ..Research findings on immune evasion of EHV-1 will be compared with those of other herpesviruses of veterinary importance...
  41. doi request reprint Effects of interferon on immediate-early mRNA and protein levels in sensory neuronal cells infected with herpes simplex virus type 1 or pseudorabies virus
    Nina Van Opdenbosch
    Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    Vet Microbiol 152:401-6. 2011
    ..The latter finding indicates that PRV efficiently circumvents IFN-mediated translation inhibition by interfering with phosphorylation of eIF2α...
  42. ncbi request reprint The role of dendritic cells in alphaherpesvirus infections: archetypes and paradigms
    Gerlinde R Van De Walle
    Faculty of Veterinary Medicine, Department of Virology, Parasitology, and Immunology, Ghent University, Salisburylaan, 9820 Merelbeke, Belgium
    Rev Med Virol 19:338-58. 2009
    ..Finally, recent knowledge on the potential of alphaherpesviruses as vectors for DC stimulation and their use for immunotherapy is presented...
  43. ncbi request reprint Virus complement evasion strategies
    Herman W Favoreel
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    J Gen Virol 84:1-15. 2003
    ....
  44. pmc Viral serine/threonine protein kinases
    Thary Jacob
    Department of Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
    J Virol 85:1158-73. 2011
    ..The current review provides an overview of the different viral serine/threonine protein kinases of several large DNA viruses and discusses their function, importance, and potential as antiviral drug targets...
  45. pmc Involvement of sialoadhesin in entry of porcine reproductive and respiratory syndrome virus into porcine alveolar macrophages
    Nathalie Vanderheijden
    Laboratory of Virology, Faculty of Veterinary Medicine, Flanders Interuniversity Institute of Biotechnology VIB, 5830 AA Boxmeer, The Netherlands
    J Virol 77:8207-15. 2003
    ..The ability of porcine sialoadhesin to mediate endocytosis was demonstrated by specific internalization of MAb41D3 into PAM. Altogether, these results show that sialoadhesin is involved in the entry process of PRRSV in PAM...
  46. ncbi request reprint Rho'ing in and out of cells: viral interactions with Rho GTPase signaling
    Celine Van den Broeke
    Department of Virology, Parasitology, and Immunology Faculty of Veterinary Medicine Ghent University Ghent, Belgium
    Small Gtpases 5:e28318. 2014
    ....
  47. ncbi request reprint Bitter-sweet symphony: glycan-lectin interactions in virus biology
    Wander Van Breedam
    Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    FEMS Microbiol Rev 38:598-632. 2014
    ..Finally, the review outlines how recent advances in the glycan-lectin field might be transformed into promising new approaches to antiviral therapy. ..
  48. doi request reprint Natural killer cells: frequency, phenotype and function in healthy cats
    Ben L Vermeulen
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Vet Immunol Immunopathol 150:69-78. 2012
    ..This study is a good reference for NK cell numbers, both absolute and relative, phenotype and function in several anatomical compartments of healthy cats and for cat-specific cytotoxic assays involving both NK and NKT cells...