Affiliation: Ghent University
- Abnormal sleep architecture and refractory nocturnal enuresisKarlien Dhondt
Pediatric Sleep Centre, Ghent University Hospital, Ghent, Belgium
J Urol 182:1961-5. 2009..Children with enuresis are generally believed to have sleep that is too deep with decreased arousability. We investigated sleep characteristics in children with refractory nocturnal enuresis...
- Hypocretin-1 deficiency in a girl with ROHHAD syndromeKarlien Dhondt
Pediatric Sleep Centre, Centre for Neurophysiological Monitoring Unit, Department of Pediatrics, Ghent University Hospital, Ghent, Belgium
Pediatrics 132:e788-92. 2013..The diagnosis was confirmed by showing an absence of hypocretin-1 in the cerebrospinal fluid. We discuss potential pathophysiological implications as well as symptomatic treatment options. ..
- Childhood narcolepsy with partial facial cataplexy: a diagnostic dilemmaKarlien Dhondt
Department of Child Neurology, Pediatric Sleep Centre, Ghent University Hospital, De Pintelaan 185, B 9000 Ghent, Belgium
Sleep Med 10:797-8. 2009..The first symptoms were excessive daytime sleepiness, partial facial cataplexy and a serious behavioral disorder. Hypocretin-1 level (Hrt-1) in CSF was undetectable...
- Anti-NMDA-receptor encephalitis in a 3 year old patient with chromosome 6p21.32 microdeletion including the HLA clusterHelene Verhelst
Department of Paediatric Neurology, Ghent University Hospital, De Pintelaan 185, B 9000 Gent, Belgium
Eur J Paediatr Neurol 15:163-6. 2011..Moreover, array-comparative genomic hybridization in this patient revealed an inherited microdeletion in chromosomeband 6p21.32, including the HLA-DPB1 and HLA-DPB2 genes. The clinical relevance of this microdeletion is discussed...