Gert De Meerleer

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. ncbi request reprint Phase II study of a four-week hypofractionated external beam radiotherapy regimen for prostate cancer: report on acute toxicity
    Guy Soete
    Department of Radiotherapy, Oncology Center AZ VUB, Jette, Belgium
    Radiother Oncol 80:78-81. 2006
  2. ncbi request reprint Intensity-modulated radiation therapy for prostate cancer: late morbidity and results on biochemical control
    Gert O De Meerleer
    Department of Radiation Therapy, Ghent University Hospital, Gent, Belgium
    Radiother Oncol 82:160-6. 2007
  3. ncbi request reprint The magnetic resonance detected intraprostatic lesion in prostate cancer: planning and delivery of intensity-modulated radiotherapy
    Gert De Meerleer
    Department of Radiation Oncology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Radiother Oncol 75:325-33. 2005
  4. doi request reprint Intensity-modulated arc therapy with simultaneous integrated boost in the treatment of primary irresectable cervical cancer. Treatment planning, quality control, and clinical implementation
    Katrien Vandecasteele
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Strahlenther Onkol 185:799-807. 2009
  5. doi request reprint Intensity-modulated radiotherapy as primary therapy for prostate cancer: report on acute toxicity after dose escalation with simultaneous integrated boost to intraprostatic lesion
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 72:799-807. 2008
  6. doi request reprint Completion surgery after intensity-modulated arc therapy in the treatment of locally advanced cervical cancer: feasibility, surgical outcome, and oncologic results
    Philippe Tummers
    Division of Gynecologic Oncology, Departments of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium
    Int J Gynecol Cancer 23:877-83. 2013
  7. doi request reprint Salvage stereotactic body radiotherapy for patients with limited prostate cancer metastases: deferring androgen deprivation therapy
    Patrick Berkovic
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Clin Genitourin Cancer 11:27-32. 2013
  8. doi request reprint Hypofractionated high-dose radiation therapy for prostate cancer: long-term results of a multi-institutional phase II trial
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 84:e483-90. 2012
  9. doi request reprint Hypofractionated intensity-modulated arc therapy for lymph node metastasized prostate cancer
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 75:1013-20. 2009
  10. doi request reprint Delineation of the postprostatectomy prostate bed using computed tomography: interobserver variability following the EORTC delineation guidelines
    Piet Ost
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 81:e143-9. 2011

Detail Information

Publications36

  1. ncbi request reprint Phase II study of a four-week hypofractionated external beam radiotherapy regimen for prostate cancer: report on acute toxicity
    Guy Soete
    Department of Radiotherapy, Oncology Center AZ VUB, Jette, Belgium
    Radiother Oncol 80:78-81. 2006
    ..To evaluate the early side effects of a short course hypofractionated radiotherapy regimen in prostate cancer...
  2. ncbi request reprint Intensity-modulated radiation therapy for prostate cancer: late morbidity and results on biochemical control
    Gert O De Meerleer
    Department of Radiation Therapy, Ghent University Hospital, Gent, Belgium
    Radiother Oncol 82:160-6. 2007
    ..To report on late morbidity and biochemical relapse-free survival (bRFS) after intensity-modulated radiation therapy (IMRT) for prostate cancer...
  3. ncbi request reprint The magnetic resonance detected intraprostatic lesion in prostate cancer: planning and delivery of intensity-modulated radiotherapy
    Gert De Meerleer
    Department of Radiation Oncology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Radiother Oncol 75:325-33. 2005
    ..It may be of benefit to focus the highest dose to the intraprostatic lesion (GTVMRI) using intensity-modulated radiotherapy (IMRT). Therefore, the visualization of the GTVMRI and its inclusion into computer optimization is mandatory...
  4. doi request reprint Intensity-modulated arc therapy with simultaneous integrated boost in the treatment of primary irresectable cervical cancer. Treatment planning, quality control, and clinical implementation
    Katrien Vandecasteele
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Strahlenther Onkol 185:799-807. 2009
    ..To report on the planning procedure, quality control, and clinical implementation of intensity-modulated arc therapy (IMAT) delivering a simultaneous integrated boost (SIB) in patients with primary irresectable cervix carcinoma...
  5. doi request reprint Intensity-modulated radiotherapy as primary therapy for prostate cancer: report on acute toxicity after dose escalation with simultaneous integrated boost to intraprostatic lesion
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 72:799-807. 2008
    ....
  6. doi request reprint Completion surgery after intensity-modulated arc therapy in the treatment of locally advanced cervical cancer: feasibility, surgical outcome, and oncologic results
    Philippe Tummers
    Division of Gynecologic Oncology, Departments of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium
    Int J Gynecol Cancer 23:877-83. 2013
    ..Therefore, the idea of surgery after chemoradiation in case of LACC or bulky disease was adopted. One of the concerns regarding surgery following chemoradiotherapy is surgery-related morbidity...
  7. doi request reprint Salvage stereotactic body radiotherapy for patients with limited prostate cancer metastases: deferring androgen deprivation therapy
    Patrick Berkovic
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Clin Genitourin Cancer 11:27-32. 2013
    ..We investigated whether repeated stereotactic body radiotherapy (SBRT) of oligometastatic disease is able to defer the initiation of palliative androgen deprivation therapy (ADT) in patients with low-volume bone and lymph node metastases...
  8. doi request reprint Hypofractionated high-dose radiation therapy for prostate cancer: long-term results of a multi-institutional phase II trial
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 84:e483-90. 2012
    ..To report late gastrointestinal (GI) and genitourinary (GU) toxicity, biochemical and clinical outcomes, and overall survival after hypofractionated radiation therapy for prostate cancer (PC)...
  9. doi request reprint Hypofractionated intensity-modulated arc therapy for lymph node metastasized prostate cancer
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 75:1013-20. 2009
    ..To determine the planning results and acute toxicity after hypofractionated intensity-modulated arc radiotherapy and androgen deprivation for lymph node metastasized (Stage N1) prostate cancer...
  10. doi request reprint Delineation of the postprostatectomy prostate bed using computed tomography: interobserver variability following the EORTC delineation guidelines
    Piet Ost
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 81:e143-9. 2011
    ..The present study aims to assess the interobserver agreement of prostate bed delineation after radical prostatectomy using CT alone as proposed by the European Organization for Research and Treatment of Cancer (EORTC) guidelines...
  11. doi request reprint Developments in external beam radiotherapy for prostate cancer
    Nicolaas Lumen
    Department of Urology, Ghent University Hospital, Ghent, Belgium
    Urology 82:5-10. 2013
    ..The aim of this review is to provide the physician involved in the treatment of PC an overview of the current indications of EBRT, to focus on some recent developments in EBRT, and to highlight promising new indications for EBRT. ..
  12. doi request reprint High-dose adjuvant radiotherapy after radical prostatectomy with or without androgen deprivation therapy
    Piet Ost
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 83:960-5. 2012
    ..To retrospectively evaluate the outcome and toxicity in patients receiving high-dose (>69 Gy) adjuvant radiotherapy (HD-ART) and the impact of androgen deprivation therapy (ADT)...
  13. doi request reprint Volumetric arc therapy and intensity-modulated radiotherapy for primary prostate radiotherapy with simultaneous integrated boost to intraprostatic lesion with 6 and 18 MV: a planning comparison study
    Piet Ost
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 79:920-6. 2011
    ..Additionally, the use of 6-MV photons was compared with 18-MV photons for all techniques...
  14. doi request reprint Salvage intensity-modulated radiotherapy for rising PSA after radical prostatectomy
    Gert De Meerleer
    Department of Radiation Oncology, Ghent University Hospital, Belgium
    Radiother Oncol 89:205-13. 2008
    ....
  15. doi request reprint Acute radiation-induced nocturia in prostate cancer patients is associated with pretreatment symptoms, radical prostatectomy, and genetic markers in the TGFβ1 gene
    Sofie De Langhe
    Department of Basic Medical Sciences, Ghent University, Gent, Belgium
    Int J Radiat Oncol Biol Phys 85:393-9. 2013
    ..In this study, we investigated the association among dosimetric, clinical, and TGFβ1 polymorphisms and the development of acute radiation-induced nocturia in prostate cancer patients...
  16. doi request reprint Postoperative intensity-modulated arc therapy for cervical and endometrial cancer: a prospective report on toxicity
    Katrien Vandecasteele
    Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 84:408-14. 2012
    ..To report on toxicity after postoperative intensity-modulated arc therapy (IMAT) for cervical (CC) and endometrial cancer (EC)...
  17. doi request reprint Improving positioning in high-dose radiotherapy for prostate cancer: safety and visibility of frequently used gold fiducial markers
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 83:46-52. 2012
    ....
  18. doi request reprint A matched control analysis of adjuvant and salvage high-dose postoperative intensity-modulated radiotherapy for prostate cancer
    Piet Ost
    Department of Radiotherapy, Ghent University Hospital, Belgium
    Int J Radiat Oncol Biol Phys 80:1316-22. 2011
    ..We performed a matched case analysis comparing high-dose adjuvant intensity modulated radiotherapy (A-IMRT) with salvage IMRT (S-IMRT)...
  19. doi request reprint High-dose salvage intensity-modulated radiotherapy with or without androgen deprivation after radical prostatectomy for rising or persisting prostate-specific antigen: 5-year results
    Piet Ost
    Department of Radiotherapy, Ghent University Hospital, Belgium
    Eur Urol 60:842-9. 2011
    ..Long-term results with salvage radiotherapy (SRT) for a biochemical recurrence after radical prostatectomy (RP) are poor. It has been suggested that radiotherapy doses >70 Gy might result in improved outcome...
  20. doi request reprint Hypofractionated intensity-modulated arc therapy for lymph node metastasized prostate cancer: early late toxicity and 3-year clinical outcome
    Valerie Fonteyne
    Department of Radiation Oncology, Ghent University Hospital, Belgium Electronic address
    Radiother Oncol 109:229-34. 2013
    ..We evaluated clinical outcome, gastro-intestinal (GI) and genito-urinary (GU) toxicity after intensity modulated arc radiotherapy (IMAT)+androgen deprivation (AD) for N1 PCa...
  21. doi request reprint Whole abdominopelvic radiotherapy using intensity-modulated arc therapy in the palliative treatment of chemotherapy-resistant ovarian cancer with bulky peritoneal disease: a single-institution experience
    Gert De Meerleer
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 79:775-81. 2011
    ..To retrospectively review our experience with whole abdominopelvic radiotherapy (WAPRT) using intensity-modulated arc therapy in the palliative treatment of chemotherapy-resistant ovarian cancer with bulky peritoneal disease...
  22. ncbi request reprint Late radiotherapy-induced lower intestinal toxicity (RILIT) of intensity-modulated radiotherapy for prostate cancer: the need for adapting toxicity scales and the appearance of the sigmoid colon as co-responsible organ for lower intestinal toxicity
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Radiother Oncol 84:156-63. 2007
    ..Late radiotherapy-induced lower intestinal toxicity (RILIT) after intensity-modulated radiotherapy (IMRT) for prostate cancer. 2. The correlation between late RILIT and volume parameters of the rectum, sigmoid colon and small bowel...
  23. doi request reprint Adjuvant high-dose intensity-modulated radiotherapy after radical prostatectomy for prostate cancer: clinical results in 104 patients
    Piet Ost
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Eur Urol 56:669-75. 2009
    ..Approximately 25% of patients treated with adjuvant radiotherapy (RT) will develop a biochemical failure within 5 yr after RT when doses of 60-64 Gray (Gy) are used...
  24. doi request reprint Prognostic factors influencing prostate cancer-specific survival in non-castrate patients with metastatic prostate cancer
    Piet Ost
    Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium
    Prostate 74:297-305. 2014
    ..In non-castrate prostate cancer (PCa), the prognostic value of the number of metastases on prostate cancer-specific survival (PCSS) is not well studied...
  25. doi request reprint Hypofractionated frameless stereotactic intensity-modulated radiotherapy with whole brain radiotherapy for the treatment of 1-3 brain metastases
    Bruno De Potter
    Department of Radiotherapy, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Neurol Sci 34:647-53. 2013
    ..The 1-year actuarial local and distant brain control was 66 and 75 %, respectively. WBRT + HSRT is an effective treatment for patients with up to three brain metastases...
  26. doi request reprint Urinary toxicity after high dose intensity modulated radiotherapy as primary therapy for prostate cancer
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, Belgium
    Radiother Oncol 92:42-7. 2009
    ..2) Time evolution of pre-IMRT and IMRT-induced acute and late GU toxicity...
  27. doi request reprint Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies
    Liv Veldeman
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Lancet Oncol 9:367-75. 2008
    ..This review shows evidence of reduced toxicity for various tumour sites by use of IMRT. The findings regarding local control and overall survival are generally inconclusive...
  28. doi request reprint Early biomarkers related to secondary primary cancer risk in radiotherapy treated prostate cancer patients: IMRT versus IMAT
    Joke Werbrouck
    Department of Basic Medical Sciences, Ghent University, Gent, Belgium
    Radiother Oncol 107:377-81. 2013
    ....
  29. ncbi request reprint Evaluation of the Sinmed Mastercouch as replacement for a standard couch
    Sofie Gillis
    Department of Radiotherapy, Ghent University Hospital, Gent, Belgium
    Radiother Oncol 75:227-36. 2005
    ..Introducing into practice a new carbon-fibre couch necessitates its evaluation with regard to the present clinical situation...
  30. ncbi request reprint Intensity-modulated radiotherapy as primary treatment for prostate cancer: acute toxicity in 114 patients
    Gert De Meerleer
    Department of Radiotherapy, Ghent University Hospital, De Pintelaan 185, B 9000 Ghent, Belgium
    Int J Radiat Oncol Biol Phys 60:777-87. 2004
    ..At Ghent University Hospital, intensity-modulated radiotherapy (IMRT) is used to increase the dose to the prostate and/or seminal vesicles. We report on acute toxicity in 114 patients who received IMRT for prostate cancer...
  31. doi request reprint Analysis of prostate bed motion using daily cone-beam computed tomography during postprostatectomy radiotherapy
    Piet Ost
    Department of Radiotherapy, Ghent University Hospital, Ghent, Belgium
    Int J Radiat Oncol Biol Phys 79:188-94. 2011
    ..The role of an adaptive radiotherapy schedule (ART) was investigated...
  32. pmc Clinical results after high-dose intensity-modulated radiotherapy for high-risk prostate cancer
    Valerie Fonteyne
    Department of Radiotherapy, Ghent University Hospital, 9000 Ghent, Belgium
    Adv Urol 2012:368528. 2012
    ..AD was a significant predictor of bRFS (P = 0.001) and cRFS (P = 0.01). Conclusion. High-dose IMRT and AD for high-risk PC offers excellent biochemical and clinical control with low toxicity...
  33. doi request reprint Radiotherapy and surgery-an indispensable duo in the treatment of retroperitoneal sarcoma
    Lien Van De Voorde
    Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium
    Cancer 117:4355-64. 2011
    ..The current results indicated that preoperative external-beam RT followed by radical surgery seems to be the preferred sequence, and adding intraoperative RT is a safe procedure for dose escalation in the upper abdomen...
  34. ncbi request reprint Direct segment aperture and weight optimization for intensity-modulated radiotherapy of prostate cancer
    Gert De Meerleer
    Department of Radiotherapy, Gent University Hospital, Belgium
    Strahlenther Onkol 180:136-43. 2004
    ..To describe the implementation and to evaluate the results of direct segment aperture optimization using the segment outline and weight adapting tool (SOWAT) in intensity-modulated radiotherapy (IMRT) for prostate cancer...
  35. doi request reprint Image-guided radiation therapy: many roads lead to Rome?
    Judit Boda-Heggemann
    Int J Radiat Oncol Biol Phys 70:646-7; author reply 647. 2008
  36. ncbi request reprint The role of nuclear medicine in the prediction and detection of radiation-associated normal pulmonary and cardiac damage
    Ingeborg Goethals
    Division of Nuclear Medicine, University Hospital Ghent, Ghent, Belgium
    J Nucl Med 44:1531-9. 2003
    ....