Research Topics
Species | Wout BoerjanSummaryAffiliation: Ghent University Country: Belgium Publications
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Publications
Lignin biosynthesisWout Boerjan
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology, Ghent University, K L Ledeganckstraat 35, B 9000 Gent, Belgium
Annu Rev Plant Biol 54:519-46. 2003..In some cases, the potential value for agriculture of transgenic plants with modified lignin structure has been demonstrated. This review presents a current picture of monolignol biosynthesis, polymerization, and lignin structure...
Downregulation of cinnamoyl-coenzyme A reductase in poplar: multiple-level phenotyping reveals effects on cell wall polymer metabolism and structureJean Charles Leplé
Department of Plant Systems Biology, Flanders Institute for Biotechnology, 9052 Gent, Belgium
Plant Cell 19:3669-91. 2007..Finally, chemical pulping of wood derived from 5-year-old, field-grown transgenic lines revealed improved pulping characteristics, but growth was affected in all transgenic lines tested...- Mass spectrometry-based sequencing of lignin oligomersKris Morreel
Department of Plant Systems Biology, Flanders Institute for Biotechnology, B 9052 Ghent, Belgium
Plant Physiol 153:1464-78. 2010..Interestingly, based on molecular mass data of the unknown monomeric and dimeric substructures, at least 10 unknown monomeric units or interunit linkage types were observed, one of which was identified as an arylglycerol end unit... - Phenolic profiling of caffeic acid O-methyltransferase-deficient poplar reveals novel benzodioxane oligolignolsKris Morreel
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology, Ghent University, B-9052 Ghent, Belgium
Plant Physiol 136:4023-36. 2004.... 
Engineering traditional monolignols out of lignin by concomitant up-regulation of F5H1 and down-regulation of COMT in ArabidopsisRuben Vanholme
Department of Plant Systems Biology, VIB, 9052 Gent, Belgium
Plant J 64:885-97. 2010..These genetic interactions must be taken into account in future cell-wall engineering strategies...- Mass spectrometry-based fragmentation as an identification tool in lignomicsKris Morreel
Department of Plant Systems Biology, VIB, B 9052 Ghent, Belgium
Anal Chem 82:8095-105. 2010..Consequently, this work lays the foundation for a detailed characterization of the lignome in different plant species, mutants, and transgenics and for the MS-based sequencing of lignin oligomers and (neo)lignans... - Genetical metabolomics of flavonoid biosynthesis in Populus: a case studyKris Morreel
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology (VIB, Ghent University, B-9052 Gent, Belgium
Plant J 47:224-37. 2006..The data indicate that the combination of metabolite profiling with QTL analysis is a valuable tool to identify control points in a complex metabolic pathway of closely related compounds... - Gene expression during the induction, maintenance, and release of dormancy in apical buds of poplarAntje Rohde
Department of Plant Systems Biology, Flanders Institute for Biotechnology VIB, 9052 Gent, Belgium
J Exp Bot 58:4047-60. 2007..These regulatory genes could be involved in the differentiation of stipule-like leaf organs protecting the bud, or act during the growth-dormancy transition in the meristem, revealing commonalities between para- and endodormancy... - A systems biology view of responses to lignin biosynthesis perturbations in ArabidopsisRuben Vanholme
Department of Plant Systems Biology, VIB, B 9052 Ghent, Belgium
Plant Cell 24:3506-29. 2012..Together, our data provide insight into lignin biosynthesis and the metabolic network it is embedded in and provide a systems view of the plant's response to pathway perturbations... - Lignin engineeringRuben Vanholme
Department of Plant Systems Biology, Flanders Institute for Biotechnology VIB, Technologiepark 927, Gent, Belgium
Curr Opin Plant Biol 11:278-85. 2008.... - Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cellsLaurens Pauwels
Department of Plant Systems Biology, Flanders Institute for Biotechnology, Ghent University, 9052 Ghent, Belgium
Proc Natl Acad Sci U S A 105:1380-5. 2008.... - Breeding with rare defective alleles (BRDA): a natural Populus nigra HCT mutant with modified lignin as a case studyBartel Vanholme
Department of Plant Systems Biology, Flanders Institute for Biotechnology VIB, Technologiepark 927, 9052, Gent, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, Technologiepark 927, 9052, Gent, Belgium
New Phytol 198:765-76. 2013..The proposed breeding strategy, called 'breeding with rare defective alleles' (BRDA), should be widely applicable, independent of the target gene or the species... - Bud set in poplar--genetic dissection of a complex trait in natural and hybrid populationsAntje Rohde
Department of Plant Systems Biology, Flanders Institute for Biotechnology VIB, Gent, Belgium
New Phytol 189:106-21. 2011..These regions of 1.83-4.25 Mbp in size, containing between 202 and 394 genes, form the basis for further molecular-genetic dissection of bud set... - Molecular phenotyping of lignin-modified tobacco reveals associated changes in cell-wall metabolism, primary metabolism, stress metabolism and photorespirationRebecca Dauwe
Department of Plant Systems Biology, Flanders Institute for Biotechnology, Technologiepark 927, 9052 Gent, Belgium
Plant J 52:263-85. 2007..Our data provide a molecular picture of a plant's response to altered monolignol biosynthesis... - Transcription factor WRKY23 assists auxin distribution patterns during Arabidopsis root development through local control on flavonol biosynthesisWim Grunewald
Department of Plant Systems Biology, VIB, 9052 Ghent, Belgium
Proc Natl Acad Sci U S A 109:1554-9. 2012..Our results suggest a model in which WRKY23 is part of a transcriptional feedback loop of auxin on its own transport through local regulation of flavonol biosynthesis... - A molecular timetable for apical bud formation and dormancy induction in poplarTom Ruttink
Department of Plant Systems Biology, Flanders Institute for Biotechnology, 9052 Gent, Belgium
Plant Cell 19:2370-90. 2007.... - Temperature signals contribute to the timing of photoperiodic growth cessation and bud set in poplarAntje Rohde
Department of Plant Systems Biology, VIB, 9052 Gent, Belgium
Tree Physiol 31:472-82. 2011..The ability of perennial plants to integrate additional environmental signals with photoperiod signaling may add to short-term acclimatization to the predicted longer growing seasons in future climates... - Metabolic engineering of novel lignin in biomass cropsRuben Vanholme
Department of Plant Systems Biology, VIB, Technologiepark 927, Gent, Belgium
New Phytol 196:978-1000. 2012..Finally, the status of detection and identification of compounds by phenolic profiling is discussed, as phenolic profiling serves in pathway elucidation and for the detection of incorporation of alternative lignin monomers... - Perturbation of indole-3-butyric acid homeostasis by the UDP-glucosyltransferase UGT74E2 modulates Arabidopsis architecture and water stress toleranceVanesa B Tognetti
Department of Plant Systems Biology, VIB, Ghent University, 9052 Gent, Belgium
Plant Cell 22:2660-79. 2010.... - Modeling lignin polymerization. I. Simulation model of dehydrogenation polymersFrederik R D van Parijs
Department of Plant Systems Biology, VIB, 9052 Ghent, Belgium
Plant Physiol 153:1332-44. 2010..These are cleaved in analytical methods used to study lignin composition, namely thioacidolysis and derivatization followed by reductive cleavage, under pulping conditions, and in some lignocellulosic biomass pretreatments... - Potential of Arabidopsis systems biology to advance the biofuel fieldRuben Vanholme
Department of Plant Systems Biology, Flanders Institute for Biotechnology VIB, 9052 Ghent, Belgium
Trends Biotechnol 28:543-7. 2010..We develop our ideas with a focus on the lignin biosynthetic pathway, because lignin is among the most important factors determining cell wall recalcitrance... - Joint GC-MS and LC-MS platforms for comprehensive plant metabolomics: repeatability and sample pre-treatmentRuben t'Kindt
Laboratory of Medical Biochemistry and Clinical Analysis, Ghent University, Harelbekestraat 72, B 9000 Ghent, Belgium
J Chromatogr B Analyt Technol Biomed Life Sci 877:3572-80. 2009..Below room temperature (instead of heated) extraction does not significantly degrade GC-MS performance but one should be more cautious with respect to residual enzymatic activity in the plant extract... - Profiling of oligolignols reveals monolignol coupling conditions in lignifying poplar xylemKris Morreel
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology, Ghent University, B-9052 Ghent, Belgium
Plant Physiol 136:3537-49. 2004..Importantly, the structures of two oligomers, each containing a gamma-p-hydroxybenzoylated syringyl unit, strongly suggest that sinapyl p-hydroxybenzoate is an authentic precursor for lignin polymerization in poplar... - Biotechnology and the domestication of forest treesWout Boerjan
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology VIB, Ghent University, Technologiepark 927, B 9052 Gent, Belgium
Curr Opin Biotechnol 16:159-66. 2005..Not only has the potential of transgenic trees with optimized yield and quality traits been demonstrated in field trials, but progress in genetical genomics and association genetics promise quantum leaps forward for tree improvement... - Genome-wide characterization of the lignification toolbox in ArabidopsisJeroen Raes
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology, Ghent University, Technologiepark 927, B-9052 Gent, Belgium
Plant Physiol 133:1051-71. 2003..Together, these data describe the full complement of monolignol biosynthesis genes in Arabidopsis, provide a unified nomenclature, and serve as a basis for further functional studies... - PtABI3 impinges on the growth and differentiation of embryonic leaves during bud set in poplarAntje Rohde
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology, Ghent University, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium
Plant Cell 14:1885-901. 2002..These experiments reveal that ABI3 plays a role in the cellular differentiation of vegetative tissues, in addition to its function in seeds... - Genome-wide identification of NBS resistance genes in Populus trichocarpaAnnegret Kohler
Unité Mixte de Recherche INRA UHP 1136 Interactions Arbres Microorganismes, Institut National de la Recherche Agronomique, Centre de Recherches de Nancy, 54280 Champenoux, France
Plant Mol Biol 66:619-36. 2008..The transcripts of only 34 NBS-LRR genes were detected in rust-infected and non-infected leaves using a whole-genome oligoarray. None showed an altered expression two days post inoculation... - Identification of the structure and origin of a thioacidolysis marker compound for ferulic acid incorporation into angiosperm lignins (and an indicator for cinnamoyl CoA reductase deficiency)John Ralph
US Dairy Forage Research Center, USDA Agricultural Research Service, Madison, WI 53706, USA
Plant J 53:368-79. 2008..Moreover, ferulic acid incorporation provides a new mechanism for producing branch points in the polymer. The findings sharply contradict those reported in a recent study on CCR-deficient Arabidopsis... - Genetically modified lignin below groundDavid W Hopkins
Nat Biotechnol 25:168-9. 2007 - Metabolite profiling reveals a role for atypical cinnamyl alcohol dehydrogenase CAD1 in the synthesis of coniferyl alcohol in tobacco xylemIsabelle Damiani
, , 24 chemin de Borderouge, BP 42617, F-31326, Castanet, France
Plant Mol Biol 59:753-69. 2005..Together, our results support a significant contribution of CAD1 to the synthesis of coniferyl alcohol in planta, along with the previously characterized CAD2 enzymes... - Molecular changes associated with the setting up of secondary growth in aspenDamien van Raemdonck
Laboratory of Plant Biotechnology, , , B-1160 Brussels, Belgium
J Exp Bot 56:2211-27. 2005..These results suggest that these genes have a potential role in vascular tissue development and/or functioning... - Lignin: genetic engineering and impact on pulpingMarie Baucher
, , Brussels, Belgium
Crit Rev Biochem Mol Biol 38:305-50. 2003..Fine-tuned modification of lignin content, composition, or both is now achievable and could have important economic and environmental benefits... - Field and pulping performances of transgenic trees with altered lignificationGilles Pilate
, , , BP 20619, Ardon, 45166 Olivet, France
Nat Biotechnol 20:607-12. 2002..This work highlights the potential of engineering wood quality for more environmentally benign papermaking without interfering with tree growth or fitness...