Stijn I Blot

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. ncbi Nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in critically ill patients: clinical outcome and length of hospitalization
    Stijn Blot
    Department of Intensive Care, Ghent University Hospital, B 9000 Ghent, Belgium
    Clin Infect Dis 34:1600-6. 2002
  2. ncbi Evaluation of outcome in critically ill patients with nosocomial enterobacter bacteremia: results of a matched cohort study
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Belgium
    Chest 123:1208-13. 2003
  3. ncbi Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort study
    Stijn Blot
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Intensive Care Med 29:471-5. 2003
  4. ncbi Reappraisal of attributable mortality in critically ill patients with nosocomial bacteraemia involving Pseudomonas aeruginosa
    S Blot
    Department of Intensive Care, Ghent University Hospital, Belgium
    J Hosp Infect 53:18-24. 2003
  5. ncbi Effects of nosocomial candidemia on outcomes of critically ill patients
    Stijn I Blot
    Department of Intensive Care, Ghent University Hospital, Gent, Belgium
    Am J Med 113:480-5. 2002
  6. ncbi Outcome and attributable mortality in critically Ill patients with bacteremia involving methicillin-susceptible and methicillin-resistant Staphylococcus aureus
    Stijn I Blot
    Ghent University Hospital, Department of Intensive Care, De Pintelaan 185, B 9000 Ghent, Belgium
    Arch Intern Med 162:2229-35. 2002
  7. ncbi Clinical impact of nosocomial Klebsiella bacteremia in critically ill patients
    S I Blot
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Eur J Clin Microbiol Infect Dis 21:471-3. 2002
  8. ncbi Health implications of antimicrobial resistance for patients with acute kidney injury and bloodstream infection
    Eric A J Hoste
    Intensive Care Department, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Infect Control Hosp Epidemiol 28:1107-10. 2007
  9. ncbi Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with hematological malignancies
    Dominique M Vandijck
    Department of Intensive Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Intensive Care Med 34:847-55. 2008
  10. ncbi Antimicrobial resistance in nosocomial bloodstream infection associated with pneumonia and the value of systematic surveillance cultures in an adult intensive care unit
    Pieter O Depuydt
    Department of Intensive Care, Ghent University Hospital, Gent, Belgium
    Crit Care Med 34:653-9. 2006

Detail Information

Publications52

  1. ncbi Nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in critically ill patients: clinical outcome and length of hospitalization
    Stijn Blot
    Department of Intensive Care, Ghent University Hospital, B 9000 Ghent, Belgium
    Clin Infect Dis 34:1600-6. 2002
    ..032) were independently associated with in-hospital mortality (P<.05). Antibiotic resistance in nosocomial bacteremia caused by gram-negative bacteria does not adversely affect the outcome for critically ill patients...
  2. ncbi Evaluation of outcome in critically ill patients with nosocomial enterobacter bacteremia: results of a matched cohort study
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Belgium
    Chest 123:1208-13. 2003
    ..To evaluate the clinical impact of nosocomial Enterobacter bacteremia in critically ill patients...
  3. ncbi Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort study
    Stijn Blot
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Intensive Care Med 29:471-5. 2003
    ..To determine outcome and attributable mortality in critically ill patients with nosocomial bacteremia involving A. baumannii...
  4. ncbi Reappraisal of attributable mortality in critically ill patients with nosocomial bacteraemia involving Pseudomonas aeruginosa
    S Blot
    Department of Intensive Care, Ghent University Hospital, Belgium
    J Hosp Infect 53:18-24. 2003
    ..In conclusion, P. aeruginosa bacteraemia is associated with a clinically relevant attributable mortality (15%). However, we could not find statistical evidence of P. aeruginosa being an independent predictor of mortality...
  5. ncbi Effects of nosocomial candidemia on outcomes of critically ill patients
    Stijn I Blot
    Department of Intensive Care, Ghent University Hospital, Gent, Belgium
    Am J Med 113:480-5. 2002
    ..To determine whether nosocomial candidemia is associated with increased mortality in intensive care unit (ICU) patients...
  6. ncbi Outcome and attributable mortality in critically Ill patients with bacteremia involving methicillin-susceptible and methicillin-resistant Staphylococcus aureus
    Stijn I Blot
    Ghent University Hospital, Department of Intensive Care, De Pintelaan 185, B 9000 Ghent, Belgium
    Arch Intern Med 162:2229-35. 2002
    ....
  7. ncbi Clinical impact of nosocomial Klebsiella bacteremia in critically ill patients
    S I Blot
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Eur J Clin Microbiol Infect Dis 21:471-3. 2002
    ..905). In conclusion, after adjusting accurately for severity of underlying disease and acute illness, no difference in mortality was found between ICU patients with Klebsiella bacteremia and their matched control subjects...
  8. ncbi Health implications of antimicrobial resistance for patients with acute kidney injury and bloodstream infection
    Eric A J Hoste
    Intensive Care Department, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Infect Control Hosp Epidemiol 28:1107-10. 2007
    ..We found that infection with an antimicrobial-resistant organism did not adversely affect clinical outcome in this specific cohort, which already has a high mortality rate...
  9. ncbi Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with hematological malignancies
    Dominique M Vandijck
    Department of Intensive Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Intensive Care Med 34:847-55. 2008
    ....
  10. ncbi Antimicrobial resistance in nosocomial bloodstream infection associated with pneumonia and the value of systematic surveillance cultures in an adult intensive care unit
    Pieter O Depuydt
    Department of Intensive Care, Ghent University Hospital, Gent, Belgium
    Crit Care Med 34:653-9. 2006
    ..To study the occurrence of multiple-drug-resistant pathogens in nosocomial bloodstream infection associated with pneumonia. To evaluate prediction of multiple drug resistance by systematic surveillance cultures...
  11. ncbi Dynamics of C-reactive protein and white blood cell count in critically ill patients with nosocomial Gram positive vs. Gram negative bacteremia: a historical cohort study
    Dominique M Vandijck
    Department of Intensive Care Medicine, Ghent University Hospital Ghent University, Faculty of Medicine and Health Sciences, De Pintelaan 185, Ghent, Belgium
    BMC Infect Dis 7:106. 2007
    ..Gram negative bacteremia (GNB), and to assess the potential benefit of serial measurements of both biomarkers in terms of early antimicrobial therapy initiation...
  12. ncbi Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Ghent, Belgium
    Clin Infect Dis 41:1591-8. 2005
    ..We evaluate clinical and economic outcomes associated with nosocomial central venous catheter-related bloodstream infection (CR-BSI) in intensive care unit (ICU) patients...
  13. ncbi Blood stream infections of abdominal origin in the intensive care unit: characteristics and determinants of death
    Jan J De Waele
    Intensive Care Unit, Ghent University Hospital, Ghent, Belgium
    Surg Infect (Larchmt) 9:171-7. 2008
    ..Blood stream infections (BSI) of abdominal origin are associated with a high mortality rate. We hypothesized that both patient and microbiological factors determine death in critically ill patients who develop such infections...
  14. ncbi Relative adrenal insufficiency in patients with severe acute pancreatitis
    Jan J De Waele
    Intensive Care Unit 1K12 C, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
    Intensive Care Med 33:1754-60. 2007
    ..This study aimed to analyse the incidence of relative adrenal insufficiency (RAI) in these patients, to identify factors associated with RAI and to describe how adrenal responsiveness affects outcome...
  15. ncbi Determinants and impact of multidrug antibiotic resistance in pathogens causing ventilator-associated-pneumonia
    Pieter O Depuydt
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, B 9000 Gent, Belgium
    Crit Care 12:R142. 2008
    ..We aimed to identify the determinants of MDR versus non-MDR microbial aetiology in VAP and assessed whether MDR versus non-MDR VAP was independently associated with increased 30-day mortality...
  16. ncbi Update on the management of infection in patients with severe sepsis
    Dominique M Vandijck
    Department of Intensive Care Medicine, Faculty of Medicine and Health Sciences, Ghent University Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Dimens Crit Care Nurs 27:244-8. 2008
    ..This review article highlights the anti-infective approach of the management of sepsis...
  17. ncbi Effect of nosocomial bloodstream infection on the outcome of critically ill patients with acute renal failure treated with renal replacement therapy
    Eric A J Hoste
    Intensive Care Unit, Department of Public Health, Ghent University Hospital, Gent, Belgium
    J Am Soc Nephrol 15:454-62. 2004
    ..Nevertheless, the outcome was not influenced by the presence of bloodstream infection. The high mortality observed in ARF patients could therefore not be attributed to the higher incidence of bloodstream infection...
  18. ncbi Intra-abdominal hypertension in patients with severe acute pancreatitis
    Jan J De Waele
    Intensive Care Unit, Ghent University Hospital, Gent, Belgium
    Crit Care 9:R452-7. 2005
    ..We therefore studied patient factors associated with the development of intra-abdominal hypertension (IAH), the incidence of organ failure associated with IAH, and the effect on outcome in patients with severe acute pancreatitis (SAP)...
  19. ncbi De-escalation after empirical meropenem treatment in the intensive care unit: fiction or reality?
    Jan J De Waele
    Department of Critical Care Medicine, Ghent University Hospital, 9000 Ghent, Belgium
    J Crit Care 25:641-6. 2010
    ..De-escalation of antimicrobial therapy is often advocated to reduce the use of broad-spectrum antibiotics in critically ill patients. However, little data are available on the application of this strategy in daily clinical practice...
  20. ncbi Thrombocytopenia and outcome in critically ill patients with bloodstream infection
    Dominique M Vandijck
    Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium
    Heart Lung 39:21-6. 2010
    ..However, few data are available describing this effect and its relationship with outcomes in specific subgroups of ICU patients...
  21. ncbi Prevention of nosocomial infections in intensive care patients
    Dominique M Vandijck
    Department of General Internal Medicine and Infectious Diseases, Ghent University Hospital, Ghent, Belgium
    Nurs Crit Care 15:251-6. 2010
    ..As such, a first and critical step should be to increase critical care nurses' adherence to the recommendations of the Centers for Disease Control and Prevention...
  22. ncbi Clinical relevance of Aspergillus isolation from respiratory tract samples in critically ill patients
    Koenraad H Vandewoude
    Department of Intensive Care, Ghent University Hospital, Ghent, Belgium
    Crit Care 10:R31. 2006
    ....
  23. ncbi Daily cost of antimicrobial therapy in patients with Intensive Care Unit-acquired, laboratory-confirmed bloodstream infection
    Dominique M Vandijck
    Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, Ghent, Belgium
    Int J Antimicrob Agents 31:161-5. 2008
    ..The antibiotic cost associated with ICU-acquired, laboratory-confirmed BSI is significant and should be reduced by implementing infection control measures and preventive strategies...
  24. ncbi The role of nurses working in emergency and critical care environments in the prevention of intravascular catheter-related bloodstream infections
    Dominique M Vandijck
    Faculty of Medicine and Health Sciences, Ghent University, Intensive Care Department of the Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Int Emerg Nurs 17:60-8. 2009
    ....
  25. ncbi Sodium bicarbonate versus THAM in ICU patients with mild metabolic acidosis
    Eric A Hoste
    Intensive Care Unit, Ghent University Hospital, Gent, Belgium
    J Nephrol 18:303-7. 2005
    ..The aim of this study was to compare the efficacy and adverse effects of a single dose of sodium bicarbonate and THAM in intensive care unit (ICU) patients with mild metabolic acidosis...
  26. ncbi Outcome of acute kidney injury in severe burns: a systematic review and meta-analysis
    Nele Brusselaers
    Burn Unit, Ghent University Hospital, Ghent University, Ghent, Belgium
    Intensive Care Med 36:915-25. 2010
    ..Several definitions of AKI have been used, but the RIFLE 'consensus' classification is nowadays considered the gold standard, enabling a more objective comparison of populations...
  27. ncbi Implementation of an evidence-based sepsis program in the intensive care unit: evident or not?
    Dominique M Vandijck
    Department of General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Crit Care 13:193. 2009
    ....
  28. ncbi Outcome and changes over time in survival following severe burns from 1985 to 2004
    Nele Brusselaers
    Intensive Care Department, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
    Intensive Care Med 31:1648-53. 2005
    ..Taking into account that our patients over the past 20 years have been progressively less extensively burned and hence have a lesser at risk for death, survival following severe burns has continued to improve...
  29. ncbi A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients
    Stijn I Blot
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium
    Am J Respir Crit Care Med 186:56-64. 2012
    ..The clinical relevance of Aspergillus-positive endotracheal aspirates in critically ill patients is difficult to assess...
  30. ncbi Adherence to and efficacy and safety of an insulin protocol in the critically ill: a prospective observational study
    Sandra G Oeyen
    Department of Intensive Care, Ghent University Hospital, Ghent, Belgium
    Am J Crit Care 16:599-608. 2007
    ..Blood glucose control during acute illness has been associated with improved outcomes...
  31. ncbi Perioperative factors determine outcome after surgery for severe acute pancreatitis
    Jan J De Waele
    Intensive Care Unit, Ghent University Hospital, Gent, Belgium
    Crit Care 8:R504-11. 2004
    ....
  32. ncbi Documented and clinically suspected bacterial infection precipitating intensive care unit admission in patients with hematological malignancies: impact on outcome
    Dominique D Benoit
    Department of Intensive Care, Medical Intensive Care Unit, 12K12IB, De Pintelaan 185, 9000, Ghent, Belgium
    Intensive Care Med 31:934-42. 2005
    ..To assess the impact of documented and clinically suspected bacterial infection precipitating ICU admission on in-hospital mortality in patients with hematological malignancies...
  33. ncbi Effects of delayed oxygenation assessment on time to antibiotic delivery and mortality in patients with severe community-acquired pneumonia
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Faculty of Medicine and Health Science, Ghent University, Belgium
    Crit Care Med 35:2509-14. 2007
    ....
  34. ncbi An evaluation of family-centered care services and organization of visiting policies in Belgian intensive care units: a multicenter survey
    Dominique M Vandijck
    Department of General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Heart Lung 39:137-46. 2010
    ..However, despite the data available, practice has not changed much to incorporate these findings...
  35. ncbi Patient to nurse ratio and risk of ventilator-associated pneumonia in critically ill patients
    Stijn I Blot
    Ghent University Hospital, Ghent University, Belgium
    Am J Crit Care 20:e1-9. 2011
    ..To determine how the patient to nurse ratio affects risk for ventilator-associated pneumonia...
  36. ncbi Candida peritonitis
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Ghent, Belgium
    Curr Opin Crit Care 13:195-9. 2007
    ..The review highlights current insights in the epidemiology, diagnosis and therapy of Candida peritonitis, focusing on complicated secondary and tertiary peritonitis...
  37. ncbi Evidence-based guidelines for the prevention of ventilator-associated pneumonia: results of a knowledge test among intensive care nurses
    Stijn I Blot
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Intensive Care Med 33:1463-7. 2007
    ..To determine intensive care nurses' knowledge of evidence-based guidelines for the prevention of ventilator-associated pneumonia (VAP)...
  38. ncbi No early respiratory benefit with CVVHDF in patients with acute renal failure and acute lung injury
    Eric A J Hoste
    Intensive Care Unit, and Renal Division, Ghent University Hospital, Ghent, Belgium
    Nephrol Dial Transplant 17:2153-8. 2002
    ..Because haemofilter conditions should be comparable between patients, we opted for an evaluation of the effects during a 24-h period. Results of this trial can guide future studies in non-renal patients with acute lung injury...
  39. ncbi Estimates of attributable mortality of systemic candida infection in the ICU
    Stijn I Blot
    J Crit Care 18:130-1; author reply 131. 2003
  40. ncbi Community-acquired versus nosocomial Klebsiella pneumonia bacteremia: clinical features, treatment outcomes, and clinical implication of antimicrobial resistance
    Dominique M Vandijck
    J Korean Med Sci 22:770-1. 2007
  41. ncbi Antimicrobial resistance among clinical isolates of Pseudomonas aeruginosa from patients in a teaching hospital
    Dominique M Vandijck
    Jpn J Infect Dis 60:416. 2007
  42. ncbi Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infection due to Pseudomonas aeruginosa
    Dominique M Vandijck
    J Infect 53:289; author reply 289-90. 2006
  43. ncbi Microbiologically documented nosocomial infections after coronary artery bypass surgery without cardiopulmonary bypass
    Dominique M Vandijck
    J Thorac Cardiovasc Surg 133:590-1; author reply 591. 2007
  44. ncbi Prediction of morbidity and mortality on admission to a burn unit
    Nele Brusselaers
    Plast Reconstr Surg 120:360-1; author reply 361. 2007
  45. ncbi Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia
    Kemal Agbaht
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care Med 35:2064-70. 2007
    ..To assess whether bacteremic ventilator-associated pneumonia (B-VAP) differs in terms of risk factors, organisms, and outcomes from nonbacteremic VAP (NB-VAP)...
  46. ncbi Severity prediction in acute pancreatitis using the CT severity index. A self-fulfilling prophecy
    Jan J De Waele
    JOP 7:432-3; author reply 433-4. 2006
  47. ncbi Recurrent catheter-related bloodstream infections: risk factors and outcome
    Dominique M Vandijck
    Int J Infect Dis 11:371-2. 2007
  48. ncbi Bacteremia in patients with febrile neutropenia following chemotherapy
    Dominique M Vandijck
    Int J Infect Dis 12:449. 2008
  49. ncbi Comment: Epidemiology, risk factors, and outcomes of Candida albicans versus non-albicans candidemia in nonneutropenic patients
    Dominique M Vandijck
    Ann Pharmacother 41:1916-7; author reply 1917. 2007
  50. ncbi Invasive devices: no need? No use!
    Stijn I Blot
    Intensive Care Med 33:209-11. 2007
  51. ncbi Trends in mortality in coronary artery bypass graft patients with acute renal failure
    Stijn I Blot
    Crit Care Med 36:656. 2008
  52. ncbi Obstacles to implementing evidence-based guidelines
    Sonia O Labeau
    Respir Care 53:505-6; author reply 506. 2008