Stijn I Blot

Summary

Affiliation: Ghent University
Country: Belgium

Publications

  1. ncbi request reprint Fungal sepsis in the ICU: are we doing better? Trends in incidence, diagnosis, and outcome
    S Blot
    Department of Internal Medicine, Faculty of Medicine and Health Science, Ghent University, Ghent, Belgium
    Minerva Anestesiol 79:1396-405. 2013
  2. pmc Prevention of ventilator-associated pneumonia in intensive care units: an international online survey
    Marie Laurence Lambert
    Healthcare associated Infections Unit, Scientific Institute of Public Health, Rue Juliette Wytsmanstraat 14, Brussels, 1050, Belgium
    Antimicrob Resist Infect Control 2:9. 2013
  3. doi request reprint A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients
    Stijn I Blot
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium
    Am J Respir Crit Care Med 186:56-64. 2012
  4. pmc Impact estimates of nosocomial bloodstream infection: looking from a different angle
    Dirk Vogelaers
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Crit Care 15:169. 2011
  5. pmc Essentials for selecting antimicrobial therapy for intra-abdominal infections
    Stijn Blot
    Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    Drugs 72:e17-32. 2012
  6. pmc Severe burn injury in Europe: a systematic review of the incidence, etiology, morbidity, and mortality
    Nele Brusselaers
    Department of General Internal Medicine, Infectious Diseases and Psychosomatic Medicine, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium
    Crit Care 14:R188. 2010
  7. pmc Discriminating invasive fungal infection from colonization
    Stijn Blot
    Crit Care 12:412; author reply 412. 2008
  8. pmc Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections
    Kristen Chalmet
    Ghent University, Belgium
    BMC Infect Dis 10:262. 2010
  9. pmc Subclinical iron deficiency is a strong predictor of bacterial vaginosis in early pregnancy
    Hans Verstraelen
    Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, De Pintelaan 185, B 9000 Ghent, Belgium
    BMC Infect Dis 5:55. 2005
  10. doi request reprint Is Candida really a threat in the ICU?
    Stijn Blot
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, Belgium
    Curr Opin Crit Care 14:600-4. 2008

Detail Information

Publications89

  1. ncbi request reprint Fungal sepsis in the ICU: are we doing better? Trends in incidence, diagnosis, and outcome
    S Blot
    Department of Internal Medicine, Faculty of Medicine and Health Science, Ghent University, Ghent, Belgium
    Minerva Anestesiol 79:1396-405. 2013
    ..Outcome following fungal sepsis remains cumbersome. Given the availability of potent antifungal agents any progress in survival is likely to come from a more timely diagnosis. ..
  2. pmc Prevention of ventilator-associated pneumonia in intensive care units: an international online survey
    Marie Laurence Lambert
    Healthcare associated Infections Unit, Scientific Institute of Public Health, Rue Juliette Wytsmanstraat 14, Brussels, 1050, Belgium
    Antimicrob Resist Infect Control 2:9. 2013
    ..Our objective was to survey attitudes and practices of ICUs doctors in the field of VAP prevention...
  3. doi request reprint A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients
    Stijn I Blot
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium
    Am J Respir Crit Care Med 186:56-64. 2012
    ..The clinical relevance of Aspergillus-positive endotracheal aspirates in critically ill patients is difficult to assess...
  4. pmc Impact estimates of nosocomial bloodstream infection: looking from a different angle
    Dirk Vogelaers
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Crit Care 15:169. 2011
    ..As a consequence, untargeted interventional studies focused on infection prevention should use occurrence rate of infection rather than mortality as outcome variable...
  5. pmc Essentials for selecting antimicrobial therapy for intra-abdominal infections
    Stijn Blot
    Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    Drugs 72:e17-32. 2012
    ..For patients in whom the source can be adequately controlled, antimicrobial therapy should be restricted to a short course (e.g. 3-7 days in peritonitis)...
  6. pmc Severe burn injury in Europe: a systematic review of the incidence, etiology, morbidity, and mortality
    Nele Brusselaers
    Department of General Internal Medicine, Infectious Diseases and Psychosomatic Medicine, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium
    Crit Care 14:R188. 2010
    ..The aim of this study was to describe the European hospitalized population with severe burn injury, including the incidence, etiology, risk factors, mortality, and causes of death...
  7. pmc Discriminating invasive fungal infection from colonization
    Stijn Blot
    Crit Care 12:412; author reply 412. 2008
  8. pmc Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections
    Kristen Chalmet
    Ghent University, Belgium
    BMC Infect Dis 10:262. 2010
    ....
  9. pmc Subclinical iron deficiency is a strong predictor of bacterial vaginosis in early pregnancy
    Hans Verstraelen
    Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Ghent University, Ghent University Hospital, De Pintelaan 185, B 9000 Ghent, Belgium
    BMC Infect Dis 5:55. 2005
    ....
  10. doi request reprint Is Candida really a threat in the ICU?
    Stijn Blot
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, Belgium
    Curr Opin Crit Care 14:600-4. 2008
    ..Three issues were appraised. First is the prevalence of Candida. Second is the relevance of nonblood cultures positive for Candida and multisite colonization. Third is the importance of invasive candidiasis in terms of mortality...
  11. ncbi request reprint Critical issues in the clinical management of complicated intra-abdominal infections
    Stijn Blot
    Intensive Care Department, Ghent University Hospital, Belgium
    Drugs 65:1611-20. 2005
    ..In general, antimicrobial therapy should be continued for 5-7 days. If sepsis is still present after 1 week, a diagnostic work up should be performed, and if necessary a surgical reintervention should be considered...
  12. ncbi request reprint Colonization status and appropriate antibiotic therapy for nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in an intensive care unit
    Stijn Blot
    Department of Intensive Care, Ghent University Hospital, Gent, Belgium
    Infect Control Hosp Epidemiol 26:575-9. 2005
    ..The relationship between knowledge of colonization caused by antibiotic-resistant gram-negative bacteria (ABR-GNB) and rate of appropriate initial antibiotic therapy for subsequent bacteremia was evaluated...
  13. ncbi request reprint Limiting the attributable mortality of nosocomial infection and multidrug resistance in intensive care units
    S Blot
    Intensive Care Department, Ghent University Hospital and Health Care Department, University College Ghent, Ghent, Belgium
    Clin Microbiol Infect 14:5-13. 2008
    ..g., contaminated devices or intra-abdominal collections or leakages. In the latter case, timely surgical intervention is essential. In addition, haemodynamic stabilisation and optimisation of tissue oxygenation can save lives...
  14. ncbi request reprint Effect of fluconazole consumption on long-term trends in candidal ecology
    S Blot
    Department of Intensive Care, Ghent University Hospital De Pintelaan 185, 9000 Ghent, Belgium
    J Antimicrob Chemother 58:474-7. 2006
    ..The effect of the volume of consumption of fluconazole on candidal ecology, however, is poorly investigated...
  15. ncbi request reprint Measuring the impact of multidrug resistance in nosocomial infection
    Stijn Blot
    Intensive Care Department, Ghent University Hospital, Ghent, Belgium
    Curr Opin Infect Dis 20:391-6. 2007
    ..Methodological techniques dealing with the problem of confounding are discussed and current findings in how multidrug resistance affects outcome in patients with nosocomial infection are highlighted...
  16. ncbi request reprint Evidence-based guidelines for the prevention of ventilator-associated pneumonia: results of a knowledge test among intensive care nurses
    Stijn I Blot
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Intensive Care Med 33:1463-7. 2007
    ..To determine intensive care nurses' knowledge of evidence-based guidelines for the prevention of ventilator-associated pneumonia (VAP)...
  17. doi request reprint Epidemiology and outcome of nosocomial bloodstream infection in elderly critically ill patients: a comparison between middle-aged, old, and very old patients
    Stijn Blot
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, Ghent, Belgium
    Crit Care Med 37:1634-41. 2009
    ..We investigated the epidemiology of nosocomial bloodstream infection in elderly intensive care unit (ICU) patients...
  18. ncbi request reprint Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Ghent, Belgium
    Clin Infect Dis 41:1591-8. 2005
    ..We evaluate clinical and economic outcomes associated with nosocomial central venous catheter-related bloodstream infection (CR-BSI) in intensive care unit (ICU) patients...
  19. pmc The rising problem of antimicrobial resistance in the intensive care unit
    Nele Brusselaers
    Department of General Internal Medicine, Infectious Diseases, and Psychosomatic Medicine, Ghent University Hospital, Ghent, Belgium
    Ann Intensive Care 1:47. 2011
    ..Constant evaluation of current practice on basis of trends in MDR and antibiotic consumption patterns is essential to make progress in this problematic matter...
  20. doi request reprint What is new in the prevention of ventilator-associated pneumonia?
    Stijn Blot
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium
    Curr Opin Pulm Med 17:155-9. 2011
    ..Strict adherence to preventive measures reduces the risk of VAP. The objective of this paper is to review what has come forward in recent years in the nonpharmacological prevention of VAP...
  21. doi request reprint Patient to nurse ratio and risk of ventilator-associated pneumonia in critically ill patients
    Stijn I Blot
    Ghent University Hospital, Ghent University, Belgium
    Am J Crit Care 20:e1-9. 2011
    ..To determine how the patient to nurse ratio affects risk for ventilator-associated pneumonia...
  22. ncbi request reprint Management of invasive candidiasis in critically ill patients
    Stijn Blot
    Intensive Care Department, Ghent University Hospital, Ghent, Belgium
    Drugs 64:2159-75. 2004
    ..The main goal is to maintain a balance between optimal prevention and timely initiation of therapy on one hand, and to minimise selection pressure in order to avoid a shift towards less susceptible Candida species on the other hand...
  23. ncbi request reprint Candida peritonitis
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Ghent, Belgium
    Curr Opin Crit Care 13:195-9. 2007
    ..The review highlights current insights in the epidemiology, diagnosis and therapy of Candida peritonitis, focusing on complicated secondary and tertiary peritonitis...
  24. ncbi request reprint Influence of matching for exposure time on estimates of attributable mortality caused by nosocomial bacteremia in critically ill patients
    Stijn Blot
    Intensive Care Department, Ghent University Hospital, Gent, Belgium
    Infect Control Hosp Epidemiol 26:352-6. 2005
    ..To evaluate the influence of matching on exposure time on estimates of attributable mortality of nosocomial bacteremia as assessed by matched cohort studies...
  25. ncbi request reprint Health implications of antimicrobial resistance for patients with acute kidney injury and bloodstream infection
    Eric A J Hoste
    Intensive Care Department, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Infect Control Hosp Epidemiol 28:1107-10. 2007
    ..We found that infection with an antimicrobial-resistant organism did not adversely affect clinical outcome in this specific cohort, which already has a high mortality rate...
  26. ncbi request reprint Effects of nosocomial candidemia on outcomes of critically ill patients
    Stijn I Blot
    Department of Intensive Care, Ghent University Hospital, Gent, Belgium
    Am J Med 113:480-5. 2002
    ..To determine whether nosocomial candidemia is associated with increased mortality in intensive care unit (ICU) patients...
  27. doi request reprint Nurses' knowledge of evidence-based guidelines for the prevention of surgical site infection
    Sonia O Labeau
    Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    Worldviews Evid Based Nurs 7:16-24. 2010
    ..Prevention of surgical site infection (SSI) is an important responsibility for nurses. Knowledge of the related evidence-based recommendations is necessary to provide high-quality nursing care...
  28. ncbi request reprint Antimicrobial resistance in nosocomial bloodstream infection associated with pneumonia and the value of systematic surveillance cultures in an adult intensive care unit
    Pieter O Depuydt
    Department of Intensive Care, Ghent University Hospital, Gent, Belgium
    Crit Care Med 34:653-9. 2006
    ..To study the occurrence of multiple-drug-resistant pathogens in nosocomial bloodstream infection associated with pneumonia. To evaluate prediction of multiple drug resistance by systematic surveillance cultures...
  29. doi request reprint Impact of recent intravenous chemotherapy on outcome in severe sepsis and septic shock patients with hematological malignancies
    Dominique M Vandijck
    Department of Intensive Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Intensive Care Med 34:847-55. 2008
    ....
  30. doi request reprint Epidemiology of infection in critically ill patients with acute renal failure
    Emmelie Reynvoet
    Department of Medicine and Health Sciences, Ghent University, Ghent, Belgium
    Crit Care Med 37:2203-9. 2009
    ..Therefore, we investigated the occurrence of infection in a cohort of critically ill patients with ARF treated with renal replacement therapy (RRT). In addition, we assessed whether this infection worsened outcome...
  31. pmc Intra-abdominal hypertension in patients with severe acute pancreatitis
    Jan J De Waele
    Intensive Care Unit, Ghent University Hospital, Gent, Belgium
    Crit Care 9:R452-7. 2005
    ..We therefore studied patient factors associated with the development of intra-abdominal hypertension (IAH), the incidence of organ failure associated with IAH, and the effect on outcome in patients with severe acute pancreatitis (SAP)...
  32. pmc Dynamics of C-reactive protein and white blood cell count in critically ill patients with nosocomial Gram positive vs. Gram negative bacteremia: a historical cohort study
    Dominique M Vandijck
    Department of Intensive Care Medicine, Ghent University Hospital Ghent University, Faculty of Medicine and Health Sciences, De Pintelaan 185, Ghent, Belgium
    BMC Infect Dis 7:106. 2007
    ..Gram negative bacteremia (GNB), and to assess the potential benefit of serial measurements of both biomarkers in terms of early antimicrobial therapy initiation...
  33. pmc Perioperative factors determine outcome after surgery for severe acute pancreatitis
    Jan J De Waele
    Intensive Care Unit, Ghent University Hospital, Gent, Belgium
    Crit Care 8:R504-11. 2004
    ....
  34. ncbi request reprint Absence of excess mortality in critically ill patients with nosocomial Escherichia coli bacteremia
    Stijn Blot
    Department of Intensive Care, Ghent University Hospital, Ghent, Belgium
    Infect Control Hosp Epidemiol 24:912-5. 2003
    ..To evaluate excess mortality in critically ill patients with Escherichia coli bacteremia after adjustment for severity of illness...
  35. ncbi request reprint Effect of nosocomial bloodstream infection on the outcome of critically ill patients with acute renal failure treated with renal replacement therapy
    Eric A J Hoste
    Intensive Care Unit, Department of Public Health, Ghent University Hospital, Gent, Belgium
    J Am Soc Nephrol 15:454-62. 2004
    ..Nevertheless, the outcome was not influenced by the presence of bloodstream infection. The high mortality observed in ARF patients could therefore not be attributed to the higher incidence of bloodstream infection...
  36. pmc Determinants and impact of multidrug antibiotic resistance in pathogens causing ventilator-associated-pneumonia
    Pieter O Depuydt
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, B 9000 Gent, Belgium
    Crit Care 12:R142. 2008
    ..We aimed to identify the determinants of MDR versus non-MDR microbial aetiology in VAP and assessed whether MDR versus non-MDR VAP was independently associated with increased 30-day mortality...
  37. doi request reprint De-escalation after empirical meropenem treatment in the intensive care unit: fiction or reality?
    Jan J De Waele
    Department of Critical Care Medicine, Ghent University Hospital, 9000 Ghent, Belgium
    J Crit Care 25:641-6. 2010
    ..De-escalation of antimicrobial therapy is often advocated to reduce the use of broad-spectrum antibiotics in critically ill patients. However, little data are available on the application of this strategy in daily clinical practice...
  38. ncbi request reprint Evaluation of outcome in critically ill patients with nosocomial enterobacter bacteremia: results of a matched cohort study
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Belgium
    Chest 123:1208-13. 2003
    ..To evaluate the clinical impact of nosocomial Enterobacter bacteremia in critically ill patients...
  39. doi request reprint Blood stream infections of abdominal origin in the intensive care unit: characteristics and determinants of death
    Jan J De Waele
    Intensive Care Unit, Ghent University Hospital, Ghent, Belgium
    Surg Infect (Larchmt) 9:171-7. 2008
    ..Blood stream infections (BSI) of abdominal origin are associated with a high mortality rate. We hypothesized that both patient and microbiological factors determine death in critically ill patients who develop such infections...
  40. ncbi request reprint Relative adrenal insufficiency in patients with severe acute pancreatitis
    Jan J De Waele
    Intensive Care Unit 1K12 C, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
    Intensive Care Med 33:1754-60. 2007
    ..This study aimed to analyse the incidence of relative adrenal insufficiency (RAI) in these patients, to identify factors associated with RAI and to describe how adrenal responsiveness affects outcome...
  41. doi request reprint Update on the management of infection in patients with severe sepsis
    Dominique M Vandijck
    Department of Intensive Care Medicine, Faculty of Medicine and Health Sciences, Ghent University Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Dimens Crit Care Nurs 27:244-8. 2008
    ..This review article highlights the anti-infective approach of the management of sepsis...
  42. doi request reprint Daily cost of antimicrobial therapy in patients with Intensive Care Unit-acquired, laboratory-confirmed bloodstream infection
    Dominique M Vandijck
    Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, Ghent, Belgium
    Int J Antimicrob Agents 31:161-5. 2008
    ..The antibiotic cost associated with ICU-acquired, laboratory-confirmed BSI is significant and should be reduced by implementing infection control measures and preventive strategies...
  43. pmc Clinical relevance of Aspergillus isolation from respiratory tract samples in critically ill patients
    Koenraad H Vandewoude
    Department of Intensive Care, Ghent University Hospital, Ghent, Belgium
    Crit Care 10:R31. 2006
    ....
  44. doi request reprint Prevention of nosocomial infections in intensive care patients
    Dominique M Vandijck
    Department of General Internal Medicine and Infectious Diseases, Ghent University Hospital, Ghent, Belgium
    Nurs Crit Care 15:251-6. 2010
    ..As such, a first and critical step should be to increase critical care nurses' adherence to the recommendations of the Centers for Disease Control and Prevention...
  45. doi request reprint Thrombocytopenia and outcome in critically ill patients with bloodstream infection
    Dominique M Vandijck
    Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium
    Heart Lung 39:21-6. 2010
    ..However, few data are available describing this effect and its relationship with outcomes in specific subgroups of ICU patients...
  46. ncbi request reprint Nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in critically ill patients: clinical outcome and length of hospitalization
    Stijn Blot
    Department of Intensive Care, Ghent University Hospital, B 9000 Ghent, Belgium
    Clin Infect Dis 34:1600-6. 2002
    ..032) were independently associated with in-hospital mortality (P<.05). Antibiotic resistance in nosocomial bacteremia caused by gram-negative bacteria does not adversely affect the outcome for critically ill patients...
  47. doi request reprint Patterns of antimicrobial therapy in severe nosocomial infections: empiric choices, proportion of appropriate therapy, and adaptation rates--a multicentre, observational survey in critically ill patients
    Dirk Vogelaers
    General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Int J Antimicrob Agents 35:375-81. 2010
    ..In this study reflecting real-life practice, first-line use of meropenem provided significantly higher rates of the appropriate/adequate therapy, irrespective of presence of risk factors for MDR...
  48. ncbi request reprint Documented and clinically suspected bacterial infection precipitating intensive care unit admission in patients with hematological malignancies: impact on outcome
    Dominique D Benoit
    Department of Intensive Care, Medical Intensive Care Unit, 12K12IB, De Pintelaan 185, 9000, Ghent, Belgium
    Intensive Care Med 31:934-42. 2005
    ..To assess the impact of documented and clinically suspected bacterial infection precipitating ICU admission on in-hospital mortality in patients with hematological malignancies...
  49. ncbi request reprint Sodium bicarbonate versus THAM in ICU patients with mild metabolic acidosis
    Eric A Hoste
    Intensive Care Unit, Ghent University Hospital, Gent, Belgium
    J Nephrol 18:303-7. 2005
    ..The aim of this study was to compare the efficacy and adverse effects of a single dose of sodium bicarbonate and THAM in intensive care unit (ICU) patients with mild metabolic acidosis...
  50. pmc Implementation of an evidence-based sepsis program in the intensive care unit: evident or not?
    Dominique M Vandijck
    Department of General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Crit Care 13:193. 2009
    ....
  51. ncbi request reprint Outcome and changes over time in survival following severe burns from 1985 to 2004
    Nele Brusselaers
    Intensive Care Department, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
    Intensive Care Med 31:1648-53. 2005
    ..To investigate outcome in severely burned patients over a 20-year period and to evaluate survival over time...
  52. doi request reprint Outcome of acute kidney injury in severe burns: a systematic review and meta-analysis
    Nele Brusselaers
    Burn Unit, Ghent University Hospital, Ghent University, Ghent, Belgium
    Intensive Care Med 36:915-25. 2010
    ..Several definitions of AKI have been used, but the RIFLE 'consensus' classification is nowadays considered the gold standard, enabling a more objective comparison of populations...
  53. doi request reprint The role of nurses working in emergency and critical care environments in the prevention of intravascular catheter-related bloodstream infections
    Dominique M Vandijck
    Faculty of Medicine and Health Sciences, Ghent University, Intensive Care Department of the Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Int Emerg Nurs 17:60-8. 2009
    ....
  54. ncbi request reprint Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort study
    Stijn Blot
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Intensive Care Med 29:471-5. 2003
    ..To determine outcome and attributable mortality in critically ill patients with nosocomial bacteremia involving A. baumannii...
  55. ncbi request reprint Adherence to and efficacy and safety of an insulin protocol in the critically ill: a prospective observational study
    Sandra G Oeyen
    Department of Intensive Care, Ghent University Hospital, Ghent, Belgium
    Am J Crit Care 16:599-608. 2007
    ..Blood glucose control during acute illness has been associated with improved outcomes...
  56. ncbi request reprint Effects of delayed oxygenation assessment on time to antibiotic delivery and mortality in patients with severe community-acquired pneumonia
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Faculty of Medicine and Health Science, Ghent University, Belgium
    Crit Care Med 35:2509-14. 2007
    ....
  57. ncbi request reprint Outcome and attributable mortality in critically Ill patients with bacteremia involving methicillin-susceptible and methicillin-resistant Staphylococcus aureus
    Stijn I Blot
    Ghent University Hospital, Department of Intensive Care, De Pintelaan 185, B 9000 Ghent, Belgium
    Arch Intern Med 162:2229-35. 2002
    ....
  58. doi request reprint Prevention of ventilator-associated pneumonia with oral antiseptics: a systematic review and meta-analysis
    Sonia O Labeau
    Faculty of Healthcare Vesalius, University College Ghent, Ghent, Belgium
    Lancet Infect Dis 11:845-54. 2011
    ....
  59. doi request reprint Centers for Disease Control and Prevention guidelines for preventing central venous catheter-related infection: results of a knowledge test among 3405 European intensive care nurses
    Sonia O Labeau
    Faculty of Healthcare Vesalius, University College Ghent, Ghent, Belgium
    Crit Care Med 37:320-3. 2009
    ..To determine European intensive care unit (ICU) nurses' knowledge of guidelines for preventing central venous catheter-related infection from the Centers for Disease Control and Prevention...
  60. doi request reprint An evaluation of family-centered care services and organization of visiting policies in Belgian intensive care units: a multicenter survey
    Dominique M Vandijck
    Department of General Internal Medicine and Infectious Diseases, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium
    Heart Lung 39:137-46. 2010
    ..However, despite the data available, practice has not changed much to incorporate these findings...
  61. ncbi request reprint Emergence of antibiotic resistance in infected pancreatic necrosis
    Jan J De Waele
    Intensive Care Unit and Centre for Infectious Diseases, Ghent University Hospital, Ghent, Belgium
    Arch Surg 139:1371-5. 2004
    ..Overall, the use of antibiotics in the treatment of patients with severe acute pancreatitis has increased owing to the use of antibiotic prophylaxis...
  62. doi request reprint Burn scar assessment: a systematic review of different scar scales
    Nele Brusselaers
    Department of General Internal Medicine, Infectious Diseases and Psychosomatic Medicine, Ghent University Hospital, Ghent, Belgium
    J Surg Res 164:e115-23. 2010
    ..Yet, there is still no consensus about the optimal scale or tool to assess the characteristics and evolution. Our aim was to evaluate the clinical importance of scar scales specifically developed for burn scars...
  63. ncbi request reprint Nosocomial pneumonia: aetiology, diagnosis and treatment
    Pieter Depuydt
    Department of Intensive Care, Ghent University, De Pintelaan, Belgium
    Curr Opin Pulm Med 12:192-7. 2006
    ..This review highlights recent advances in the aetiology of nosocomial pneumonia, and in strategies to increase accuracy of diagnosis and antibiotic prescription while limiting unnecessary antibiotic consumption...
  64. doi request reprint Burn scar assessment: A systematic review of objective scar assessment tools
    Nele Brusselaers
    Department of General Internal Medicine, Ghent University Hospital, Ghent, Belgium
    Burns 36:1157-64. 2010
    ..The objective of this study was to review which tools can be used in objective burn scar assessment...
  65. ncbi request reprint Outcome in bacteremia associated with nosocomial pneumonia and the impact of pathogen prediction by tracheal surveillance cultures
    Pieter Depuydt
    Department of Intensive Care, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium
    Intensive Care Med 32:1773-81. 2006
    ..To assess whether pathogen prediction in bacteremia associated with nosocomial pneumonia (NP) by tracheal surveillance cultures improves adequacy of early antibiotic therapy and impacts mortality...
  66. doi request reprint Antimicrobial prophylaxis in liver transplant patients--a multicenter survey endorsed by the European Liver and Intestine Transplant Association
    Els Vandecasteele
    Intensive Care Unit, Ghent University Hospital, Gent, Belgium
    Transpl Int 23:182-90. 2010
    ..These findings underscore the need for randomized controlled trials to determine the optimal prophylactic antimicrobial regimen...
  67. ncbi request reprint No early respiratory benefit with CVVHDF in patients with acute renal failure and acute lung injury
    Eric A J Hoste
    Intensive Care Unit, and Renal Division, Ghent University Hospital, Ghent, Belgium
    Nephrol Dial Transplant 17:2153-8. 2002
    ..Because haemofilter conditions should be comparable between patients, we opted for an evaluation of the effects during a 24-h period. Results of this trial can guide future studies in non-renal patients with acute lung injury...
  68. doi request reprint Behavioral determinants of hand hygiene compliance in intensive care units
    David De Wandel
    Faculty of Health Care, University College Ghent, Ghent, Belgium
    Am J Crit Care 19:230-9. 2010
    ..Although hand hygiene is the most effective measure for preventing cross-infection, overall compliance is poor among health care workers...
  69. doi request reprint Polyurethane cuffed endotracheal tubes to prevent early postoperative pneumonia after cardiac surgery: a pilot study
    Jan Poelaert
    International Research Center, Ghent University, Gent, Belgium
    J Thorac Cardiovasc Surg 135:771-6. 2008
    ..We therefore postulated that use of a polyurethane cuffed tube would prevent early postoperative pneumonia through this mechanism in a population of cardiac surgical patients...
  70. doi request reprint Bacteremia in patients with febrile neutropenia following chemotherapy
    Dominique M Vandijck
    Int J Infect Dis 12:449. 2008
  71. ncbi request reprint Prediction of morbidity and mortality on admission to a burn unit
    Nele Brusselaers
    Plast Reconstr Surg 120:360-1; author reply 361. 2007
  72. ncbi request reprint Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia
    Kemal Agbaht
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care Med 35:2064-70. 2007
    ..To assess whether bacteremic ventilator-associated pneumonia (B-VAP) differs in terms of risk factors, organisms, and outcomes from nonbacteremic VAP (NB-VAP)...
  73. ncbi request reprint Estimates of attributable mortality of systemic candida infection in the ICU
    Stijn I Blot
    J Crit Care 18:130-1; author reply 131. 2003
  74. ncbi request reprint Inflammatory markers in patients with severe burn injury: what is the best indicator of sepsis?
    Dominique M Vandijck
    Burns 33:939-40; author reply 941-2. 2007
  75. pmc Community-acquired versus nosocomial Klebsiella pneumonia bacteremia: clinical features, treatment outcomes, and clinical implication of antimicrobial resistance
    Dominique M Vandijck
    J Korean Med Sci 22:770-1. 2007
  76. ncbi request reprint Obstacles to implementing evidence-based guidelines
    Sonia O Labeau
    Respir Care 53:505-6; author reply 506. 2008
  77. ncbi request reprint Severity prediction in acute pancreatitis using the CT severity index. A self-fulfilling prophecy
    Jan J De Waele
    JOP 7:432-3; author reply 433-4. 2006
  78. ncbi request reprint Comment: Epidemiology, risk factors, and outcomes of Candida albicans versus non-albicans candidemia in nonneutropenic patients
    Dominique M Vandijck
    Ann Pharmacother 41:1916-7; author reply 1917. 2007
  79. ncbi request reprint Microbiologically documented nosocomial infections after coronary artery bypass surgery without cardiopulmonary bypass
    Dominique M Vandijck
    J Thorac Cardiovasc Surg 133:590-1; author reply 591. 2007
  80. ncbi request reprint Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infection due to Pseudomonas aeruginosa
    Dominique M Vandijck
    J Infect 53:289; author reply 289-90. 2006
  81. ncbi request reprint Recurrent catheter-related bloodstream infections: risk factors and outcome
    Dominique M Vandijck
    Int J Infect Dis 11:371-2. 2007
  82. ncbi request reprint Fluid vs. air for semicontinuous intra-abdominal pressure measurements using a compliance catheter
    Jan J De Waele
    Intensive Care Med 31:598-9. 2005
  83. ncbi request reprint Invasive aspergillosis in immunocompetent patients
    Stijn I Blot
    South Med J 99:1398. 2006
  84. doi request reprint Trends in mortality in coronary artery bypass graft patients with acute renal failure
    Stijn I Blot
    Crit Care Med 36:656. 2008
  85. doi request reprint Facilitating clinician adherence to guidelines in the intensive care unit
    Dominique M Vandijck
    Crit Care Med 36:655. 2008
  86. ncbi request reprint Antimicrobial resistance among clinical isolates of Pseudomonas aeruginosa from patients in a teaching hospital
    Dominique M Vandijck
    Jpn J Infect Dis 60:416. 2007
  87. ncbi request reprint Invasive devices: no need? No use!
    Stijn I Blot
    Intensive Care Med 33:209-11. 2007
  88. ncbi request reprint High infection rates in patients with severe acute necrotizing pancreatitis
    Jan J De Waele
    Intensive Care Med 30:1248. 2004
  89. ncbi request reprint Level of knowledge articulated by intensive care nurses and clinical decision-making
    Dominique M Vandijck
    Intensive Crit Care Nurs 24:6-7. 2008