L Annemans

..To assess the cost per QALY (quality-adjusted life years) of pregabalin in the management of peripheral neuropathic pain...

..In conclusion, low-dose aspirin treatment becomes cost-saving at a very low 10-year risk of fatal CVD. The cost of gastrointestinal bleeding defines the level at which low-dose aspirin becomes cost-saving...

..Adding highly concentrated n-3 PUFAs to standard treatment in the secondary prevention after MI appears to be cost-effective in the 5 countries studied...

..This report indicates that improvements in adherence and long-term outcomes previously demonstrated for RLAI treatment in Belgium may result in substantial cost benefits to the country's healthcare system...

..Special attention was given if any of the included studies in the review also examined the cost-effectiveness of these health promotion interventions...

..Ideally, for use in health economics, QoL should be expressed in utilities. The aim of this study was to obtain reference values and utilities for QoL of GHD in adults in Belgium and the Netherlands...

..In this evaluation, a theory-based framework conceptualising equity in terms of equal access, equal treatment and equal treatment outcomes for people in equal need is used to guide the work...

..The second approach, noneconomic integration, represents a sociological perspective emphasizing the cooperative nature of their relationship...

..Effect domains include clinical effectiveness, access and equity, coordination and continuity, patient-centeredness, and cost-effectiveness...

..A list of key features (related to time horizon, clinical data input, patient subtypes, budget impact and model calibration) that an ideal model should have in order to better assist decision makers in this field is proposed...

..In conclusion, cetuximab plus irinotecan for patients with metastatic CRC, after failure on irinotecan-containing chemotherapy, is rather cost-effective compared with current care in both scenarios tested...

..Given the scarce resources that can be spent on health and health care, the objective of this study was to evaluate the long-term health and economic outcomes of controlled and maintained physical exercise in a fitness setting...

..The objective of our study was to analyze the health economic impact of ferucarbotran-enhanced magnetic resonance imaging (MRI) in the diagnosis of hepatic colorectal cancer metastases based on observed changes in medical management...

..The cost-effectiveness of everolimus and MMF versus azathioprine was assessed to 6 months posttransplantation...

..To investigate and compare the prevalence, comorbidities and management of gout in practice in the UK and Germany...

..We assessed the cost effectiveness of aprepitant-based vs standard prevention in these indications in Belgium...

..Sensitivity analyses varying life expectancy, efficacy of clopidogrel, costs of events and cost of adverse events and discount rates demonstrated the robustness of the results...

..For this reason, the adverse-event profile of opioid-based analgesics should be improved to achieve more efficient long-term pain control...

..Costs calculated from this study confirm predicted cost-effectiveness in the original model for MAL-PDT in the management of AK and BCC...

..Despite the complex and controversial construct of this syndrome, the results in terms of patient, healthcare payer and societal burden are quite consistent...

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..It is also not known how sustainable any observed effects on glycaemic control are, over time. This study was initiated to address both these issues...

..50 per day of response, and that MAL-PDT is better value for money than excision in BCC, taking a 5-year time horizon...

..77 Euros for a patient without febrile neutropenia, excluding drug costs. With the activity-based costing method it is possible to accurately demonstrate cost savings in the management of neutropenia using the newer drug therapies...

..This study aimed to estimate the cost effectiveness in the Belgian setting of atorvastatin 10 mg compared with no treatment for the primary prevention of CV events in type 2 diabetes patients without a history of CV disease...

..In conclusion, pragmatic community pharmacy-based programmes can significantly improve therapeutic outcomes in adult asthma patients...

..In conclusion, provided that a sufficient time horizon is taken and that long-term model predictions are confirmed from further follow-up from the ATAC study, anastrozole is a highly cost-effective adjuvant therapy compared to tamoxifen...

..3 million Euro per lifeyear), IBSP can be considered cost-effective, taking into account the potential risk of emerging pathogens...

..To evaluate the use and costs of medical resources before and after a diagnosis of fibromyalgia syndrome (FMS) in a large primary care population in the UK...

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..The objectives of this study were to estimate the long-term clinical consequences of such treatment as well as the resulting cost-effectiveness...

..Diabetes Care 2006;29:S4-42) to propose these services as a pharmacist intervention...

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..This situation calls for sustainable and holistic approaches to ensure the psychological and socio-economic stability of AIDS orphans and other vulnerable children...

..We evaluate clinical and economic outcomes associated with nosocomial central venous catheter-related bloodstream infection (CR-BSI) in intensive care unit (ICU) patients...

..This retrospective database study compared the three currently available ESAs, epoetin alfa (EPO-A), epoetin beta (EPO-B), and darbepoetin alfa (DARB), regarding costs and outcomes...

..The antibiotic cost associated with ICU-acquired, laboratory-confirmed BSI is significant and should be reduced by implementing infection control measures and preventive strategies...

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..The primary objective of this study was to assess the economic consequences of the use of low-dose aspirin in the primary prevention of CVD in four European countries (UK, Germany, Spain and Italy)...

..To determine the cost-effectiveness of vaccination against herpes zoster (HZ) and post-herpetic neuralgia (PHN) in individuals aged 60 years and older in Belgium...

..These positive initial results are stimulating to set up a prospective controlled randomised trial investigating the impact on quality of life, the clinical efficacy and the cost-effectiveness of this educational intervention programme...

..This study determines the injury rate (%) and the associated direct medical and indirect costs of sports injuries in Flanders...

..A global anticipated net saving of 70 million BEF (1.74 million Euro) over 2 years was estimated for the Belgian health insurance...

..Compared with current treatment with CAB, IVitra therapy was shown to be a cost-effective and cost-saving empirical treatment for PSFI in neutropenic cancer patients and BMT patients...

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..9% of the patients. In conclusion, the ACT appears to be a useful tool to determine rapidly and accurately the level of asthma control in patients presenting at community pharmacies...

..From a health economic point of view, one is interested in the costs saved by disease prevention...

..There is also a clear need for peer reviewed economic evaluations of novel therapies such as thalidomide and Bortezomib in the treatment of multiple myeloma at different stages of the disease...

..g. CABG, valve repair) in comparison with non-interventional (drug) treatment...

..Despite the awareness of the importance of health promotion in mental health care, it appears that visions and attitudes towards the potential of health promotion are in need of change...

..Human papillomavirus (HPV) infections can lead to cervical intraepithelial neoplasia (CIN) lesions, cervical cancer (CC) and genital warts (GWs). This study intended to assess the annual cost of CC, CIN and GW management in Belgium...

..To calculate the economic consequences of using alfuzosin 10 mg once daily for managing acute urinary retention (AUR) related to benign prostatic hyperplasia (BPH)...

..This study assessed the cost effectiveness of adding n-3 PUFAs to the current secondary prevention treatment versus standard prevention alone after acute MI in five countries: Australia, Belgium, Canada, Germany and Poland...

..This treatment has proven to be cost-effective in Western countries. This study assessed the cost-effectiveness of early irbesartan treatment in Asian settings...

..The ISPOR guidelines for the evaluation of retrospective analyses are a useful tool for assessing the quality of scientific posters...

..A simulation model was developed to project long-term cost consequences of the IDNT in Belgium and France...

..Whether implementing routine prolonged prophylaxis is cost-effective remains uncertain...

..End-stage renal disease (ESRD)-related health care costs are substantial. Improving clinical outcomes in patients at risk of progression to ESRD could lead to considerable health care savings...

..A numerical example illustrates our approach. We discuss the associated potential implications for public health policy and discuss how the effects of the intervention can be additionally corrected for societal preferences...

..SES is thus a cost-saving strategy in the perspective of the SSN that could therefore support the introduction of the new technology by reimbursing about 80% of its current incremental acquisition cost...

..Evidence on longer-term benefits of orlistat (>2 years) will be of importance for future decision-making...

..The success rates were similar between venlafaxine and escitalopram, but higher total costs were observed with venlafaxine...

..We performed a cost-consequence analysis in a French setting of the renoprotective benefit of irbesartan in hypertensive type 2 diabetes patients over a 25-year period...

..Despite the existing gaps in data, further research using the most current data should facilitate decisions on new vaccination strategies by describing conditions for favorable results and quantifying the margin of uncertainty...

..Administering low-dose aspirin to individuals with a 10-year risk of coronary heart disease > or =15% would result in significant cost savings for the Spanish NHS. Sensitivity analysis confirmed the robustness of these findings...

..This study assessed the health economic consequences of the use of low-dose aspirin in the primary prevention of CVD in Japan...

..Treatment of anaemia with ESAs is cost-effective and is associated with long-term gains in quality-adjusted life years...

..The aim of this study was to determine the most cost-effective time point for initiation of irbesartan treatment in hypertensive patients with type 2 diabetes and renal disease...

..The objective of this study was to estimate the cost-effectiveness of their treatment in comparison with no treatment...

..Instead, results should be presented in a non-aggregated manner that enables policy makers to value health gains according to timing and to which subpopulation they are accrued in...

..The Q3W schedule is cost saving compare to the QW schedule. It also reduces the burden of the frequent visits for the patients...

..This is the first and necessary step to improve the management of risk factors in these people, who are at increased risk for CHD...

..Standard Report Format can support the quality, transparency and exhaustiveness of the data submitted. A multidisciplinary task force developed a Standard Report Format for pharmaco-economic evaluations in Belgium...

..To develop a generic decision-analytic model to predict health and economic outcomes of different management options for cytomegalovirus (CMV) infection and disease in liver transplant patients...

..The objective of this report is to present guidance on methodologies for those undertaking such analyses or for those reviewing the results of such analyses...

..CONCLUSION: Based on the current data, bicalutamide appears to be a cost-effective option for adjuvant treatment of EPC...

..This method can improve the standardisation of the educational process; however, there is still much work to be done in order to achieve real consensus on 'learning outcomes' in pharmacoeconomics...

..Stimulants are the drugs of first choice in the treatment of ADHD. It has been suggested that full costs associated with the treatment of ADHD may be reduced by once-daily administration regimens of stimulants...