Research Topics
| Jean Francois FocantSummaryCountry: Belgium Publications
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Detail Information
Publications
Improvement of Ylang-Ylang Essential Oil Characterization by GC×GC-TOFMSMichał Brokl
Chemistry Department CART, Organic and Biological Analytical Chemistry, University of Liege, Allée du 6 Août B6c, Liège B 4000, Belgium
Molecules 18:1783-97. 2013..Compared to the most recent full GC-MS characterization, this represents 75 new compounds, essentially consisting of terpenes, terpenoid esters, and alcohols...
High-throughput biomonitoring of dioxins and polychlorinated biphenyls at the sub-picogram level in human serumJean Francois Focant
CART, Mass Spectrometry Laboratory, University of Liege, Allee de la Chimie 3, B 6c Sart Tilman, B 4000 Liege, Belgium
J Chromatogr A 1130:97-107. 2006..Data related to quality control and limit of quantification (LOQ) calculations are also presented and discussed...- Comprehensive two-dimensional gas chromatography with isotope dilution time-of-flight mass spectrometry for the measurement of dioxins and polychlorinated biphenyls in foodstuffs. Comparison with other methodsJean Francois Focant
CART Mass Spectrometry Laboratory, Chemistry Department, University of Liege, Allee de la Chimie 3, B 6c Sart Tilman, B 4000 Liege, Belgium
J Chromatogr A 1086:45-60. 2005..On a toxic equivalent (TEQ) basis, all methods, including the dioxin-responsive chemically activated luciferase gene expression (DR-CALUX) assay, produced similar responses. A cost comparison is also presented... - Recent advances in mass spectrometric measurement of dioxinsJean Francois Focant
Mass Spectrometry Laboratory, Dioxin Laboratory, University of Liege, Allee de la Chimie 3, Sart Tilman, B 4000 Liege, Belgium
J Chromatogr A 1067:265-75. 2005..We report herein some of the advances we achieved in the past years in our laboratory on the development of alternative measurement methods for those compounds... - Measurement of selected polybrominated diphenyl ethers, polybrominated and polychlorinated biphenyls, and organochlorine pesticides in human serum and milk using comprehensive two-dimensional gas chromatography isotope dilution time-of-flight mass spectroJean Francois Focant
Organic Analytical Toxicology OAT, Division of Laboratory Sciences DLS, National Center for Environmental Health NCEH, Centers for Disease Control and Prevention CDC, Atlanta, Georgia 30341, USA
Anal Chem 76:6313-20. 2004..OCP, PBDE, and PCB levels measured using the two methods were highly correlated, and the deviations between the two methods were below 20% for most analytes with concentrations above 1 ng/g milk lipids... - Optimisation and use of tandem-in-time mass spectrometry in comparison with immunoassay and HRGC/HRMS for PCDD/F screeningJ F Focant
Chemistry Department, University of Liege, Belgium
Chemosphere 43:417-24. 2001..The analysis of fly ashes from a municipal waste incinerator contaminated at different levels has then been realised. Results obtained using QISTMS, HRMS and immunoassay are compared... - Improved separation of the 209 polychlorinated biphenyl congeners using comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometryJean Francois Focant
Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, Organic Analytical Toxicology Branch, 4770 Buford Hwy NE, Mail Stop F 17, Atlanta, GA 30341, USA
J Chromatogr A 1040:227-38. 2004..This was not the case for the other investigated column sets... - Levels of PCDDs, PCDFs and PCBs in Belgian and international fast food samplesJ F Focant
Mass Spectrometry Laboratory, University of Liege, Allee de la Chimie 3, B 6c Sart Tilman, B 4000 Liege, Belgium
Chemosphere 54:137-42. 2004..7 pg WHO-TEQ/kg bw/month, including consumption of all types of analyzed meals, representing 9.5% of the PTMI. For child, a value of 14.5 pg WHO-TEQ/kg bw/month was obtained, representing 20.6% of the PTMI... - Levels and congener distributions of PCDDs, PCDFs and non-ortho PCBs in Belgian foodstuffs--assessment of dietary intakeJ F Focant
Mass Spectrometry Laboratory, University of Liege, Sart Tilman, Belgium
Chemosphere 48:167-79. 2002..00 pg WHO-TEQ/kg bw/day, for a 65 kg person) and 132.9 pg WHO-TEQ/day if cPCBs were included (2.04 pg WHO-TEQ/kg bw/day, for a 65 kg person). Meat (mainly beef), dairy products, and fish each account for roughly one third of the intake... - Fast clean-up for polychlorinated dibenzo-p-dioxins, dibenzofurans and coplanar polychlorinated biphenyls analysis of high-fat-content biological samplesJ F Focant
Mass Spectrometry Laboratory, University of Liege, Belgium
J Chromatogr A 925:207-21. 2001.... - Survey of commercial pasteurised cows' milk in Wallonia (Belgium) for the occurrence of polychlorinated dibenzo-p-dioxins, dibenzofurans and coplanar polychlorinated biphenylsJ F Focant
Mass Spectrometry Laboratory, Dioxin Laboratory, University of Liege, Allee de la Chimie 3, B 6c Sart Tilman, B 4000 Liege, Belgium
Chemosphere 52:725-33. 2003..Estimated daily intake (EDI) due to consumption of such milks was 0.34 pg TEQ/kg of body weight/day for PCDD/Fs and 0.69 pg TEQ/kg of body weight/day when cPCBs were included... - Levels and profiles of PCDDs, PCDFs and cPCBs in Belgian breast milk. Estimation of infant intakeJ F Focant
Mass Spectrometry Laboratory, University of Liege, Belgium
Chemosphere 48:763-70. 2002..This value is almost 20 times higher than the World Health Organization tolerable daily intake. A value of 103 pg TEQ/kg bw/day represents the intake of PCDDs, PCDFs and cPCBs (no mono-ortho PCBs included)... - Fast automated extraction and clean-up of biological fluids for polychlorinated dibenzo-p-dioxins, dibenzofurans and coplanar polychlorinated biphenyls analysisJean Francois Focant
Mass Spectrometry Laboratory, Dioxin Laboratory, University of Liege, Allee de la Chimie 3, B 6c Sart Tilman, B 4000 Liege, Belgium
J Chromatogr B Analyt Technol Biomed Life Sci 776:199-212. 2002..As a result, this new approach appears to be suitable for the fast sample preparation often required for such fluids in case of emergency foodstuffs analysis or during large epidemiological studies... - Environmental and human impact of an old-timer incinerator in terms of dioxin and PCB level: a case studyCatherine Pirard
Mass Spectrometry Laboratory, C A R T, University of Liege, Liege, Belgium
Environ Sci Technol 39:4721-8. 2005..When adjusted for age, PCB and PCDD/F blood levels were higher than general European populations and comparable to a similarly exposed Belgian population... - Semiautomated high-throughput extraction and cleanup method for the measurement of polybrominated diphenyl ethers, polybrominated biphenyls, and polychlorinated biphenyls in human serumAndreas Sjodin
Organic Analytical Toxicology, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway N E, Mail Stop F 17, Atlanta, GA 30341, USA
Anal Chem 76:1921-7. 2004..Mean recoveries of the (13)C-labeled internal standards ranged from 69 to 95% for the seven monitored PBDEs; 76 and 98% were recovered for BB-153 and CB-153, respectively... - Semiautomated high-throughput extraction and cleanup method for the measurement of polybrominated diphenyl ethers and polybrominated and polychlorinated biphenyls in breast milkAndreas Sjodin
National Center for Environmental Health, Division of Laboratory Sciences, Organic Analytical Toxicology Branch, Centers for Disease Control and Prevention, 4770 Buford Hwy NE Mail Stop F 17, Atlanta, Georgia 30341, USA
Anal Chem 76:4508-14. 2004..Mean recoveries of the (13)C-labeled internal standards ranged from 60 to 89% for the eight PBDE congeners; 74 and 113% were recovered for BB-153 and CB-153, respectively... 
Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United StatesAndreas Sjodin
Organic Analytical Toxicology Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3717, USA
Environ Health Perspect 112:654-8. 2004..In contrast, PCB and PBB levels were negatively correlated with sample collection year, indicating that the levels of these compounds have been decreasing since their phaseout in the 1970s...- Suitability of tandem-in-time mass spectrometry for polybrominated diphenylether measurement in fish and shellfish samples: comparison with high resolution mass spectrometryCatherine Pirard
CART, Mass Spectrometry Laboratory, University of Liege, Allee de la Chimie 3, Bat B6c Sart Tilman, B 4000 Liege, Belgium
J Chromatogr A 1115:125-32. 2006..An analytical procedure based on rapid automated sample preparation and QISTMS/MS appeared to be suitable for the measurement of PBDEs in fish and shellfish speciment under quality assurance/quality control (QA/QC) criteria... - New strategy for comprehensive analysis of polybrominated diphenyl ethers, polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls by gas chromatography coupled with mass spectrometryCatherine Pirard
Mass Spectrometry Laboratory, University of Liege, Allee de la Chimie 3, Bat B6c Sart Tilman, B 4000 Liege, Belgium
J Chromatogr A 998:169-81. 2003..The whole method has been evaluated on standard solution and quality control samples consisting of fortified beef fat. Sensitivity, selectivity, accuracy and repeatability were tested with satisfactory results... - Qualitative evaluation of thermal desorption-programmable temperature vaporization-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the analysis of selected halogenated contaminantsJean Francois Focant
Centers for Disease Control and Prevention, National Centerfor Environmental Health, Division of Laboratory Sciences, Organic Analytical Toxicology Branch, 4770 Buford Hwy NE, Mail Stop F 17, Atlanta, GA 30341, USA
J Chromatogr A 1019:143-56. 2003..Of the 58 compounds investigated, only one pair of PCBs was not resolved. All other analytes were either baseline separated into the chromatographic plane or were virtually separated using the deconvolution capability of the TOFMS... - Development of an absolute quantification method targeting growth hormone biomarkers using liquid chromatography coupled to isotope dilution mass spectrometryStephanie Kirsch
University of Liege, Chemistry Department, Mass Spectrometry Laboratory, Allee de la Chimie 3, B 6c Sart Tilman, B 4000 Liege, Belgium
J Chromatogr A 1153:300-6. 2007..Preliminary data regarding repeatability show that relative standard deviations (RSDs) range between 13 and 32% for IGFBP-3 and between 7 and 29% for IGF-1... - Concentration of polybrominated diphenyl ethers (PBDEs) in household dust from various countriesAndreas Sjodin
Centers for Disease Control and Prevention, National Center for Environmental Health, Division for Laboratory Sciences, 4770 Buford Hwy, Atlanta, GA 30341, USA
Chemosphere 73:S131-6. 2008..We conclude that further studies are required to investigate human indoor exposure to PBDEs across countries and to determine the risk factors related to indoor design factors... - Effects of a sublethal pesticide exposure on locomotor behavior: a video-tracking analysis in larval amphibiansMathieu Denoël
Laboratory of Fish and Amphibian Ethology, Behavioural Biology Unit, Department of Biology, Ecology, and Evolution, University of Liege, 22 Quai Van Beneden, 4020 Liege, Belgium
Chemosphere 90:945-51. 2013..By highlighting effects before mortality markers, video-tracking systems also show their potential as sentinels of sublethal effects of pesticides... - Comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the forensic study of cadaveric volatile organic compounds released in soil by buried decaying pig carcassesCatherine Brasseur
CART, Organic and Biological Analytical Chemistry, Chemistry Department, University of Liege, Allee du 6 Aout, B6c, Sart Tilman, B 4000 Liege, Belgium
J Chromatogr A 1255:163-70. 2012..Such screening of soil samples for cadaveric decomposition signature was successfully applied on two gravesoil sites and clearly differentiates soils at proximity of buried decaying pig carcasses from control soils...