Fabio Efficace

Summary

Affiliation: EORTC Data Center
Country: Belgium

Publications

  1. ncbi Quality of life in breast cancer patients: measurement issues in cancer clinical trials
    Fabio Efficace
    European Organisation for Research and Treatment of Cancer, Quality of Life Unit, avenue E Mounier, 83 1200 Brussels, Belgium
    Expert Rev Pharmacoecon Outcomes Res 2:57-65. 2002
  2. ncbi Health related quality of life assessment methodology and reported outcomes in randomised controlled trials of primary brain cancer patients
    F Efficace
    Quality of Life Unit, European Organisation for Research and Treatment of Cancer, EORTC Data Center, avenue E Mounier, 83, 1200 Brussels, Belgium
    Eur J Cancer 38:1824-31. 2002
  3. ncbi Spiritual issues and quality of life assessment in cancer care
    Fabio Efficace
    European Orginisation for Research and Treatment of Cancer, Brussels, Belgium
    Death Stud 26:743-56. 2002
  4. ncbi Health-related quality of life parameters as prognostic factors in a nonmetastatic breast cancer population: an international multicenter study
    Fabio Efficace
    European Organisation for Research and Treatment of Cancer, EORTC Data Center, Quality of Life Unit, Ave E Mounier 83, 1200 Brussels, Belgium
    J Clin Oncol 22:3381-8. 2004
  5. ncbi Health related quality of life in prostate carcinoma patients: a systematic review of randomized controlled trials
    Fabio Efficace
    Quality of Life Unit, European Organisation for Research and Treatment of Cancer, EORTC Data Center, Brussels, Belgium
    Cancer 97:377-88. 2003
  6. ncbi Baseline health-related quality-of-life data as prognostic factors in a phase III multicentre study of women with metastatic breast cancer
    F Efficace
    EORTC Data Centre, Quality of Life Unit, avenue E Mounier, 83 1200 Brussels, Belgium
    Eur J Cancer 40:1021-30. 2004
  7. ncbi Beyond the development of health-related quality-of-life (HRQOL) measures: a checklist for evaluating HRQOL outcomes in cancer clinical trials--does HRQOL evaluation in prostate cancer research inform clinical decision making?
    Fabio Efficace
    European Organization for Research and Treatment of Cancer EORTC, Quality of Life Unit and Genitourinary Unit, EORTC Data Center, Brussels, Belgium
    J Clin Oncol 21:3502-11. 2003
  8. ncbi Health-related quality of life in survivors of locally advanced breast cancer: an international randomised controlled phase III trial
    Andrew Bottomley
    European Organisation for Research and Treatment of Cancer, EORTC Data Center, Qualtiy of Life Unit, Brussels, Belgium
    Lancet Oncol 6:287-94. 2005
  9. ncbi Randomized, controlled trial investigating short-term health-related quality of life with doxorubicin and paclitaxel versus doxorubicin and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: European Organization for Re
    Andrew Bottomley
    Quality of Life Unit, European Organization for Research and Treatment of Cancer Data Center, Insitut Jules Bordet, Brussels, Belgium
    J Clin Oncol 22:2576-86. 2004
  10. ncbi Does a patient's self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?
    Fabio Efficace
    European Organisation for Research and Treatment of Cancer EORTC, EORTC Data Center, Quality of Life Unit, Avenue E Mounier 83, 1200 Brussels, Belgium
    Eur J Cancer 42:42-9. 2006

Detail Information

Publications24

  1. ncbi Quality of life in breast cancer patients: measurement issues in cancer clinical trials
    Fabio Efficace
    European Organisation for Research and Treatment of Cancer, Quality of Life Unit, avenue E Mounier, 83 1200 Brussels, Belgium
    Expert Rev Pharmacoecon Outcomes Res 2:57-65. 2002
    ..We propose suggestions for selecting future measures for use in a breast cancer population of patients...
  2. ncbi Health related quality of life assessment methodology and reported outcomes in randomised controlled trials of primary brain cancer patients
    F Efficace
    Quality of Life Unit, European Organisation for Research and Treatment of Cancer, EORTC Data Center, avenue E Mounier, 83, 1200 Brussels, Belgium
    Eur J Cancer 38:1824-31. 2002
    ..Based on the results of our review, we make recommendations for future investigations to avoid these shortcomings...
  3. ncbi Spiritual issues and quality of life assessment in cancer care
    Fabio Efficace
    European Orginisation for Research and Treatment of Cancer, Brussels, Belgium
    Death Stud 26:743-56. 2002
    ..It is also suggested that further research is needed to understand how the new focus on spirituality can contribute to a more comprehensive assessment of patient's QOL in cancer care...
  4. ncbi Health-related quality of life parameters as prognostic factors in a nonmetastatic breast cancer population: an international multicenter study
    Fabio Efficace
    European Organisation for Research and Treatment of Cancer, EORTC Data Center, Quality of Life Unit, Ave E Mounier 83, 1200 Brussels, Belgium
    J Clin Oncol 22:3381-8. 2004
    ..Although the literature highlights the important role of HRQOL parameters in predicting survival in advanced metastatic disease, little evidence exists for earlier stages...
  5. ncbi Health related quality of life in prostate carcinoma patients: a systematic review of randomized controlled trials
    Fabio Efficace
    Quality of Life Unit, European Organisation for Research and Treatment of Cancer, EORTC Data Center, Brussels, Belgium
    Cancer 97:377-88. 2003
    ..Given this, the authors undertook a systematic review to evaluate HRQOL assessment methodology and reported outcomes of randomized controlled clinical trials (RCTs) with prostate carcinoma patients...
  6. ncbi Baseline health-related quality-of-life data as prognostic factors in a phase III multicentre study of women with metastatic breast cancer
    F Efficace
    EORTC Data Centre, Quality of Life Unit, avenue E Mounier, 83 1200 Brussels, Belgium
    Eur J Cancer 40:1021-30. 2004
    ..However, the mechanism underlying this association remains to be precisely defined in future studies...
  7. ncbi Beyond the development of health-related quality-of-life (HRQOL) measures: a checklist for evaluating HRQOL outcomes in cancer clinical trials--does HRQOL evaluation in prostate cancer research inform clinical decision making?
    Fabio Efficace
    European Organization for Research and Treatment of Cancer EORTC, Quality of Life Unit and Genitourinary Unit, EORTC Data Center, Brussels, Belgium
    J Clin Oncol 21:3502-11. 2003
    ..Materials and..
  8. ncbi Health-related quality of life in survivors of locally advanced breast cancer: an international randomised controlled phase III trial
    Andrew Bottomley
    European Organisation for Research and Treatment of Cancer, EORTC Data Center, Qualtiy of Life Unit, Brussels, Belgium
    Lancet Oncol 6:287-94. 2005
    ..We aimed to compare the effects of such an approach with those of standard chemotherapy on health-related quality of life (HRQOL)...
  9. ncbi Randomized, controlled trial investigating short-term health-related quality of life with doxorubicin and paclitaxel versus doxorubicin and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: European Organization for Re
    Andrew Bottomley
    Quality of Life Unit, European Organization for Research and Treatment of Cancer Data Center, Insitut Jules Bordet, Brussels, Belgium
    J Clin Oncol 22:2576-86. 2004
    ..To compare health-related quality of life (HRQOL) in patients with metastatic breast cancer receiving the combination of doxorubicin and paclitaxel (AT) or doxorubicin and cyclophosphamide (AC) as first-line chemotherapy treatment...
  10. ncbi Does a patient's self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer?
    Fabio Efficace
    European Organisation for Research and Treatment of Cancer EORTC, EORTC Data Center, Quality of Life Unit, Avenue E Mounier 83, 1200 Brussels, Belgium
    Eur J Cancer 42:42-9. 2006
    ..The results suggest that social functioning, acts as a prognostic measure of survival beyond a number of previously known biomedical parameters...
  11. ncbi Prognostic value of health-related quality-of-life data in predicting survival in patients with anaplastic oligodendrogliomas, from a phase III EORTC brain cancer group study
    Murielle E L Mauer
    European Organisation for Research and Treatment of Cancer Data Center, Quality of Life Unit, Ave Mounier 83 11, Brussels, Belgium 1200
    J Clin Oncol 25:5731-7. 2007
    ..This is one of a few studies that have explored the value of baseline symptoms and health-related quality of life (HRQOL) in predicting survival in patients with brain cancer...
  12. ncbi Health-related quality of life in non-small-cell lung cancer: methodologic issues in randomized controlled trials
    Andrew Bottomley
    Quality of Life Unit, European Organization for Research and Treatment of Cancer Data Center, Belgium, Germany
    J Clin Oncol 21:2982-92. 2003
    ..To date, no detailed systematic review exists of HRQOL methodology in NSCLC RCTs...
  13. ncbi Methodological quality of patient-reported outcome research was low in complementary and alternative medicine in oncology
    Fabio Efficace
    European Organisation for Research and Treatment of Cancer EORTC, EORTC Data Center, Quality of Life Unit, avenue E Mounier, 83, 1200 Brussels, Belgium
    J Clin Epidemiol 59:1257-65. 2006
    ..To evaluate the methodological robustness of patient-reported outcomes (PROs) evaluation in complementary and alternative medicine (CAM) randomized controlled trials (RCTs) in oncology...
  14. ncbi Assessing HRQOL: a neglected issue for high-grade glioma
    Fabio Efficace
    Quality of Life Unit, EORTC, Brussels, Belgium
    Lancet Oncol 4:11-2. 2003
  15. ncbi Symptoms and patient-reported well-being: do they predict survival in malignant pleural mesothelioma? A prognostic factor analysis of EORTC-NCIC 08983: randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural
    Andrew Bottomley
    EORTC Data Center, Quality of Life Unit, avenue E Mounier, 83, 1200 Brussels, Belgium
    J Clin Oncol 25:5770-6. 2007
    ..This study reports an evaluation of the prognostic value of these factors using data gathered from a recent randomized controlled trial...
  16. ncbi Do quality-of-life randomized clinical trials support clinicians in their decision-making?
    Fabio Efficace
    J Clin Oncol 20:4126-7; author reply 4127. 2002
  17. ncbi Toward a clearer understanding of the prognostic value of health-related quality-of-life parameters in breast cancer
    Fabio Efficace
    J Clin Oncol 23:1335-6; author reply 1336. 2005
  18. ncbi Health-related quality of life and symptom assessment in clinical research of patients with hematologic malignancies: where are we now and where do we go from here?
    Fabio Efficace
    Haematologica 92:1596-8. 2007
  19. ncbi Validation of patient's self-reported social functioning as an independent prognostic factor for survival in metastatic colorectal cancer patients: results of an international study by the Chronotherapy Group of the European Organisation for Research and
    Fabio Efficace
    Italian Group for Adult Hematologic Diseases GIMEMA, GIMEMA Data Center, Health Outcome Research Unit, via Benevento, 6, 00161, Rome, Italy
    J Clin Oncol 26:2020-6. 2008
    ..The aim of this research is to validate this model on data from an independent sample...
  20. ncbi Health-related quality of life outcomes in disease-free survivors of mid-low rectal cancer after curative surgery
    Salvatore Pucciarelli
    Department of Oncological and Surgical Sciences, Section of Clinica Chirurgica II, University of Padova, Policlinico, VI piano, Via Giustiniani, 2, 35128, Padova, Italy
    Ann Surg Oncol 15:1846-54. 2008
    ..The main objective of this study was to investigate health-related quality of life (HRQOL) in terms of symptoms and functional outcomes in disease-free survivors of rectal cancer...
  21. ncbi The prognostic significance of patient-reported outcomes in cancer clinical trials
    Carolyn C Gotay
    Department of Health Care and Epidemiology, University of British Columbia, 5804 Fairview Ave, Vancouver, British Columbia, V6E 1R7 Canada
    J Clin Oncol 26:1355-63. 2008
    ..This study systematically assessed the impact of PROs on patient survival after a cancer diagnosis within the context of clinical trials...
  22. ncbi Variability and sample size requirements for health-related quality-of-life measures: understanding the challenges facing investigators
    Corneel Coens
    J Clin Oncol 23:8541-2; author reply 8542-3. 2005
  23. ncbi EORTC QLQ-INFO26: a questionnaire to assess information given to cancer patients a preliminary analysis in eight countries
    Juan Ignacio Arraras
    Oncology Department, Hospital of Navarre, Pamplona, Spain
    Psychooncology 16:249-54. 2007
    ..The resulting EORTC QLQ-INFO26 questionnaire includes four sub-scales on information regarding their cancer, medical tests, treatment and other services and several single items...
  24. ncbi Standards are needed for quality of life clinical trials
    Andrew Bottomley
    BMJ 324:1156. 2002