- Estimation of the Time Interval between the Administration of Heroin and the Sampling of Blood in Chronic InhalersNathalie Dubois
Service de Toxicologie Clinique, Medico Legale, de l Environnement et en Entreprise, Centre Hospitalier Universitaire, Liege, Belgium Centre Interfacultaire de Recherche du Médicament, Universite de Liege, Liege, Belgium
J Anal Toxicol 39:300-5. 2015..90. The overall precision of the delay estimates was 8-9 h. The delay between last heroin consumption and blood sampling in chronic drug users can be satisfactorily predicted from plasma heroin metabolites. ..
- Plasma level monitoring of the major metabolites of diacetylmorphine (heroin) by the "chasing the dragon" route in severe heroin addictsN Dubois
Laboratory of Clinical, Forensic, Environmental and Industrial Toxicology, CHU, Liege
Acta Clin Belg 68:359-67. 2013..It seemed to be not affected by the DAM dose, patient pathologies and the concomitant use of medications, methadone, street heroin and alcohol. Cocaine use was the only parameter which showed differences in heroin pharmacokinetics...
- [Rapid opiate detoxification under anesthesia (RODA)]N Dubols
1 Ingenieur industriel, Service de Toxicologie Clinique, Medico Legale, de I Environnement et en Entreprise, CHU de Liege, Belgique
Rev Med Liege 68:298-302. 2013..Naltrexone analysis allowed us to adjust doses to insure opiate receptor blockade during acute withdrawal, which is a critical period...
- Validation of the quantitative determination of tetrahydrocannabinol and its two major metabolites in plasma by ultra-high-performance liquid chromatography-tandem mass spectrometry according to the total error approachN Dubois
Service de Toxicologie Clinique, Médicolégale, de l Environnement et en Entreprise, CHU, Liege, Belgium
J Anal Toxicol 36:25-9. 2012..The acceptance limits were 30% for THC and THC-OH concentrations lower than 2 µg/L and for THC-COOH concentrations lower than 4 µg/L...