J Donnez

Summary

Country: Belgium

Publications

  1. ncbi request reprint Cryopreservation of ovarian tissue: an overview
    J Donnez
    Department of Gynecology, Catholic University of Louvain, Brussels, Belgium
    Minerva Med 100:401-13. 2009
  2. doi request reprint Pregnancy and live birth after autotransplantation of frozen-thawed ovarian tissue in a patient with metastatic disease undergoing chemotherapy and hematopoietic stem cell transplantation
    Jacques Donnez
    Universite Catholique de Louvain, Institut de Recherche Expérimentale et Clinique IREC, Unité de Recherche GYNE, Department of Gynecology, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Fertil Steril 95:1787.e1-4. 2011
  3. doi request reprint Induction of endometriotic nodules in an experimental baboon model mimicking human deep nodular lesions
    Olivier Donnez
    Department of Gynecology, Medical School, Institute of Experimental and Clinical Research, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 99:783-789.e3. 2013
  4. doi request reprint Live birth after transplantation of frozen-thawed ovarian tissue after bilateral oophorectomy for benign disease
    Jacques Donnez
    Department of Gynecology, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, and Institut de Recherche Expérimentale et Clinique, pôle de gynécologie, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 98:720-5. 2012
  5. ncbi request reprint Fertility preservation in women with ovarian endometriosis
    Jacques Donnez
    Universite Catholique de Louvain, Cliniques Universitaires St Luc, Department of Gynecology, Institut de Recherche Expérimentale et Clinique, Avenue Hippocrate 10, B 1200 Brussels, Belgium
    Front Biosci (Elite Ed) 4:1654-62. 2012
  6. doi request reprint Ulipristal acetate versus placebo for fibroid treatment before surgery
    Jacques Donnez
    Cliniques Universitaires Saint Luc Catholic University of Louvain, Brussels, Belgium
    N Engl J Med 366:409-20. 2012
  7. doi request reprint Ulipristal acetate versus leuprolide acetate for uterine fibroids
    Jacques Donnez
    Cliniques Universitaires Saint Luc Catholic University of Louvain, Brussels, Belgium
    N Engl J Med 366:421-32. 2012
  8. doi request reprint Menometrorrhagia during the premenopause: an overview
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain UCL, Cliniques Universitaires St Luc, Brussels, Belgium
    Gynecol Endocrinol 27:1114-9. 2011
  9. doi request reprint Children born after autotransplantation of cryopreserved ovarian tissue. a review of 13 live births
    Jacques Donnez
    Universite Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Department of Gynecology, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Ann Med 43:437-50. 2011
  10. doi request reprint Preservation of fertility in females with haematological malignancy
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Br J Haematol 154:175-84. 2011

Collaborators

Detail Information

Publications116 found, 100 shown here

  1. ncbi request reprint Cryopreservation of ovarian tissue: an overview
    J Donnez
    Department of Gynecology, Catholic University of Louvain, Brussels, Belgium
    Minerva Med 100:401-13. 2009
    ..This manuscript reports the techniques and results of orthotopic transplantation of cryopreserved ovarian tissue. Among almost 30 cases reported in the literature, seven live births have been achieved to date...
  2. doi request reprint Pregnancy and live birth after autotransplantation of frozen-thawed ovarian tissue in a patient with metastatic disease undergoing chemotherapy and hematopoietic stem cell transplantation
    Jacques Donnez
    Universite Catholique de Louvain, Institut de Recherche Expérimentale et Clinique IREC, Unité de Recherche GYNE, Department of Gynecology, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Fertil Steril 95:1787.e1-4. 2011
    ..To report a live birth after orthotopic transplantation of cryopreserved ovarian tissue...
  3. doi request reprint Induction of endometriotic nodules in an experimental baboon model mimicking human deep nodular lesions
    Olivier Donnez
    Department of Gynecology, Medical School, Institute of Experimental and Clinical Research, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 99:783-789.e3. 2013
    ..To establish an experimental model for the study of deep nodular endometriosis...
  4. doi request reprint Live birth after transplantation of frozen-thawed ovarian tissue after bilateral oophorectomy for benign disease
    Jacques Donnez
    Department of Gynecology, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, and Institut de Recherche Expérimentale et Clinique, pôle de gynécologie, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 98:720-5. 2012
    ..To report the restoration of ovarian function and pregnancy in a woman after bilateral oophorectomy for benign disease after autotransplantation of cryopreserved ovarian cortex...
  5. ncbi request reprint Fertility preservation in women with ovarian endometriosis
    Jacques Donnez
    Universite Catholique de Louvain, Cliniques Universitaires St Luc, Department of Gynecology, Institut de Recherche Expérimentale et Clinique, Avenue Hippocrate 10, B 1200 Brussels, Belgium
    Front Biosci (Elite Ed) 4:1654-62. 2012
    ..Preservation of ovarian tissue should be considered in all patients at serious risk of future fertility impairment, particularly before any treatment likely to result in ovarian endometriosis recurrence and/or premature ovarian failure...
  6. doi request reprint Ulipristal acetate versus placebo for fibroid treatment before surgery
    Jacques Donnez
    Cliniques Universitaires Saint Luc Catholic University of Louvain, Brussels, Belgium
    N Engl J Med 366:409-20. 2012
    ..The efficacy and safety of oral ulipristal acetate for the treatment of symptomatic uterine fibroids before surgery are uncertain...
  7. doi request reprint Ulipristal acetate versus leuprolide acetate for uterine fibroids
    Jacques Donnez
    Cliniques Universitaires Saint Luc Catholic University of Louvain, Brussels, Belgium
    N Engl J Med 366:421-32. 2012
    ..The efficacy and side-effect profile of ulipristal acetate as compared with those of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are unclear...
  8. doi request reprint Menometrorrhagia during the premenopause: an overview
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain UCL, Cliniques Universitaires St Luc, Brussels, Belgium
    Gynecol Endocrinol 27:1114-9. 2011
    ....
  9. doi request reprint Children born after autotransplantation of cryopreserved ovarian tissue. a review of 13 live births
    Jacques Donnez
    Universite Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Department of Gynecology, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Ann Med 43:437-50. 2011
    ....
  10. doi request reprint Preservation of fertility in females with haematological malignancy
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Br J Haematol 154:175-84. 2011
    ..So far, 15 live births have been obtained after orthotopic transplantation of cryopreserved ovarian tissue...
  11. doi request reprint Live birth after allografting of ovarian cortex between monozygotic twins with Turner syndrome (45,XO/46,XX mosaicism) and discordant ovarian function
    Jacques Donnez
    Universite Catholique de Louvain, Cliniques Universitaires St Luc, Department of Gynecology, Brussels, Belgium
    Fertil Steril 96:1407-11. 2011
    ..To report the restoration of ovarian function in a woman with Turner syndrome by allografting ovarian cortex from her monozygotic twin...
  12. doi request reprint Laparoscopic management of endometriomas using a combined technique of excisional (cystectomy) and ablative surgery
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 94:28-32. 2010
    ..To describe and evaluate a new technique of laparoscopic treatment of endometriomas that combines excisional and ablative surgery...
  13. doi request reprint Addition of dehydroepiandrosterone (DHEA) for poor-responder patients before and during IVF treatment improves the pregnancy rate: a randomized prospective study
    A Wiser
    IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel
    Hum Reprod 25:2496-500. 2010
    ..The aim of this study was to evaluate the effect of dehydroepiandrosterone (DHEA) supplementation on in vitro fertilization (IVF) data and outcomes among poor-responder patients...
  14. doi request reprint Cryopreservation and transplantation of ovarian tissue
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Clin Obstet Gynecol 53:787-96. 2010
    ..Transplantation of ovarian tissue pieces without a vascular pedicle requires the establishment of a new blood supply that takes 5 days. This leads to a substantial loss of follicles in the graft that may limit the longevity of the graft...
  15. doi request reprint Complications, pregnancy and recurrence in a prospective series of 500 patients operated on by the shaving technique for deep rectovaginal endometriotic nodules
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, 1200 Brussels, Belgium
    Hum Reprod 25:1949-58. 2010
    ..The debate continues between advocates of the shaving technique and supporters of bowel resection in case of deep endometriosis with rectal muscularis involvement, despite little evidence for better improvement with bowel resection...
  16. doi request reprint Live birth after allografting of ovarian cortex between genetically non-identical sisters
    Jacques Donnez
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, B 1200 Brussels, Belgium
    Hum Reprod 26:1384-8. 2011
    ..Two embryos were obtained. One embryo was frozen and the other was transferred, resulting in an ongoing pregnancy. The patient delivered a healthy baby girl weighing 3.150 g at 37 2/7 weeks of gestation...
  17. doi request reprint Frozen-thawed ovarian tissue retransplants
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Semin Reprod Med 27:472-8. 2009
    ..This article reports the techniques and results of orthotopic transplantation of cryopreserved ovarian tissue. Among almost 30 cases reported in the literature, 6 live births have been achieved to date...
  18. doi request reprint Minimally invasive gynecologic procedures
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Curr Opin Obstet Gynecol 23:289-95. 2011
    ..A heated debate is currently under way between advocates of excisional surgery and the ablative approach. With papers increasingly focusing on ovarian reserve after endometrioma surgery, a review was mandatory...
  19. ncbi request reprint Restoration of ovarian function after orthotopic (intraovarian and periovarian) transplantation of cryopreserved ovarian tissue in a woman treated by bone marrow transplantation for sickle cell anaemia: case report
    J Donnez
    Gynecology Research Unit, Universite Catholique de Louvain, Brussels, Belgium
    Hum Reprod 21:183-8. 2006
    ..Restoration of endocrine ovarian function occurred after ovarian cortical strips, biopsied and cryopreserved before chemotherapy, were reimplanted into the ovary itself and a periovarian peritoneal window...
  20. ncbi request reprint Histologic and ultrastructural evaluation of fresh and frozen-thawed human ovarian xenografts in nude mice
    M Nisolle
    Service de Gynecologie, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 74:122-9. 2000
    ..To compare histologic and ultrastructural characteristics of fresh and frozen-thawed human ovarian cortical tissue grafted into nude mice...
  21. ncbi request reprint GnRH agonist as luteal phase support in assisted reproduction technique cycles: results of a pilot study
    C Pirard
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Brussels, Belgium
    Hum Reprod 21:1894-900. 2006
    ..The aim of the study was to investigate whether intranasal (IN) administration of a GnRH agonist could provide luteal support in IVF/ICSI patients...
  22. ncbi request reprint Does ovarian surgery for endometriomas impair the ovarian response to gonadotropin?
    J Donnez
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Brussels, Belgium
    Fertil Steril 76:662-5. 2001
    ..To evaluate the ovarian response to stimulation conducted for IVF treatment in women who have undergone conservative surgery for endometriomas...
  23. ncbi request reprint Allograft of ovarian cortex between two genetically non-identical sisters: case report
    J Donnez
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, B 1200 Brussels, Belgium
    Hum Reprod 22:2653-9. 2007
    ..Restoration of ovarian function was achieved after six months. Oocyte retrieval and embryo development were demonstrated...
  24. ncbi request reprint [Treatment of endometriosis. Evaluation of preoperative therapy with danazol, gestrinone and buserelin (nasal spray and implant)]
    M Nisolle
    Department of Gynecology, Cliniques Universitaires St Luc, Brussels, Belgium
    J Gynecol Obstet Biol Reprod (Paris) 19:759-63. 1990
    ..In conclusion, preoperative use of a potent GnRH agonist, administered subcutaneously, seems to be the best therapeutic approach when associated to surgery (CO2 laser or microsurgery)...
  25. doi request reprint Alginate beads as a tool to handle, cryopreserve and culture isolated human primordial/primary follicles
    A Camboni
    Department of Gynecology, Institut de Recherche Expérimentale et Clinique, Universite Catholique de Louvain, 1200 Brussels, Belgium
    Cryobiology 67:64-9. 2013
    ..The aim of our work was to compare dimethyl sulfoxide (ME2SO) and ethylene glycol (EG) as cryoprotectants (CPAs) for slow-freezing of isolated human PFs in alginate...
  26. ncbi request reprint Endometrial laser intrauterine thermotherapy: the first series of 100 patients observed for 1 year
    J Donnez
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 74:791-6. 2000
    ....
  27. doi request reprint Inhibition of steroid sulfatase decreases endometriosis in an in vivo murine model
    S Colette
    Universite Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Department of Gynecology, Cliniques Universitaires St Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Hum Reprod 26:1362-70. 2011
    ..Steroid sulfatase (STS) is involved in estrogen biosynthesis and expressed in eutopic and ectopic endometrium of disease-free and endometriosis patients. The present study was designed to investigate its role in endometriosis development...
  28. doi request reprint Absence of aromatase protein and mRNA expression in endometriosis
    S Colette
    Universite Catholique de Louvain, Faculty of Medicine, Gynecology Unit, 1200 Brussels, Belgium
    Hum Reprod 24:2133-41. 2009
    ..The objective of the present study was to investigate its expression and localization in three distinct types of endometriosis...
  29. ncbi request reprint Endometrial laser intrauterine thermo-therapy (ELITT): a revolutionary new approach to the elimination of menorrhagia
    J Donnez
    Universite Catholique de Louvain, Cliniques Universitaires St Luc, Department of Gynecology, Brussels, Belgium
    Curr Opin Obstet Gynecol 11:363-70. 1999
    ..Among these procedures is low-dose laser radiation of the endometrium with the diode source, which is characterized by the highest incidence of amenorrhea...
  30. ncbi request reprint Comparison of G1.2/G2.2 and Sydney IVF cleavage/blastocyst sequential media for the culture of human embryos: a prospective, randomized, comparative study
    A van Langendonckt
    Department of Gynecology, Catholic University of Louvain, Brussels, Belgium
    Fertil Steril 76:1023-31. 2001
    ..1% and 36.1%, respectively). CONCLUSION(S): In our day 3 embryo transfer program, G1.2/G2.2 media were superior to Sydney IVF media, whereas both media yielded similar outcomes in our blastocyst transfer program...
  31. doi request reprint Vitrification of non-human primate immature testicular tissue allows maintenance of proliferating spermatogonial cells after xenografting to recipient mice
    J Poels
    Department of Gynecology, Medical School, Institute of Experimental and Clinical Research, Universite Catholique de Louvain, 1200 Brussels, Belgium
    Theriogenology 77:1008-13. 2012
    ..In conclusion, vitrification appears to be a promising approach, representing an alternative strategy to slow-freezing in the emerging field of ITT cryopreservation and cryobanking...
  32. ncbi request reprint LH-RH agonists offer very good protection against the adverse gynaecological effects induced by tamoxifen
    M Berliere
    Department of Gynecology IVF Unit, St Luc s Hospital, Universite Catholique de Louvain, Avenue Hippocrate 10 B 1200, Brussels, Belgium
    Eur J Cancer 40:1855-61. 2004
    ..Bone density evaluation after 2, 3 and 4 years of treatment showed no significant bone loss. LH-RH agonists offer safe protection against the gynaecological side-effects of tamoxifen in premenopausal breast cancer patients...
  33. ncbi request reprint Stereometric evaluation of peritoneal endometriosis and endometriotic nodules of the rectovaginal septum
    J Donnez
    Department of Gynaecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Avenue Hippocrate 10, B 1200 Brussels, Belgium
    Hum Reprod 11:224-8. 1996
    ..It is not the consequence of 'deep infiltrating' endometriosis but can probably develop from Mullerian rests present in the rectovaginal septum...
  34. ncbi request reprint Livebirth after orthotopic transplantation of cryopreserved ovarian tissue
    J Donnez
    Department of Gynaecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, B 1200, Brussels, Belgium
    Lancet 364:1405-10. 2004
    ..In 1997, biopsy samples of ovarian cortex were taken from a woman with stage IV Hodgkin's lymphoma and cryopreserved before chemotherapy was initiated. After her cancer treatment, the patient had premature ovarian failure...
  35. doi request reprint A series of 3190 laparoscopic hysterectomies for benign disease from 1990 to 2006: evaluation of complications compared with vaginal and abdominal procedures
    O Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    BJOG 116:492-500. 2009
    ..The aim of this study was to evaluate the complication rate after laparoscopic total hysterectomy and laparoscopic subtotal hysterectomy (LASH) in case of benign disease...
  36. doi request reprint Expression of eicosanoid biosynthetic and catabolic enzymes in peritoneal endometriosis
    J C Lousse
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Hum Reprod 25:734-41. 2010
    ..Here, we evaluated the expression of key biosynthetic and catabolic enzymes involved in this abnormal eicosanoid production in peritoneal macrophages and endometriotic lesions...
  37. doi request reprint Endothelial cells are essential for ovarian stromal tissue restructuring after xenotransplantation of isolated ovarian stromal cells
    C Dath
    Department of Gynecology, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Hum Reprod 26:1431-9. 2011
    ..To help improve the grafting technique, we investigated whether short-term xenografting of a suspension containing ovarian stromal and endothelial cells without follicles could enhance graft survival and revascularization...
  38. ncbi request reprint [Laser vaporization of ovarian endometriomas: the impact on the response to gonadotrophin stimulation]
    C Wyns
    Service de Gynecologie, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, 10, Avenue Hippocrate, 1200, Bruxelles, Belgique
    Gynecol Obstet Fertil 31:337-42. 2003
    ..To evaluate the ovarian response to stimulation for IVF in endometriosis patients who have previously undergone laparoscopic treatment of peritoneal and/or ovarian endometriosis (CO2 laser vaporization)...
  39. ncbi request reprint What are the implications of myomas on fertility? A need for a debate?
    J Donnez
    Department of Gynecology, Catholic University of Louvain, Cliniques Universitaires St Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Hum Reprod 17:1424-30. 2002
    ..The absence of an answer to this crucial question is probably due to the fact that we have not yet conducted the appropriate prospective studies required to obtain any clear results...
  40. ncbi request reprint Histologic study of ovarian endometriosis after hormonal therapy
    M Nisolle-Pochet
    Department of Gynecology, University of Louvain, Brussels, Belgium
    Fertil Steril 49:423-6. 1988
    ..In conclusion, hormonal treatment leads to an incomplete suppression of endometriotic foci...
  41. doi request reprint Xenotransplantation of human ovarian tissue to nude mice: comparison between four grafting sites
    C Dath
    Department of Gynecology, Universite Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Brussels, Belgium
    Hum Reprod 25:1734-43. 2010
    ....
  42. ncbi request reprint Endometriosis-associated infertility: evaluation of preoperative use of danazol, gestrinone, and buserelin
    J Donnez
    Department of Gynaecology, University of Louvain, Cliniques Universitaires St Luc, Brussels, Belgium
    Int J Fertil 35:297-301. 1990
    ..Nevertheless, hormonal treatment leads to an incomplete suppression of ovarian endometriotic implants and this suggests the necessity of surgically removing invasive ovarian endometriosis...
  43. doi request reprint Management of fertility preservation in prepubertal patients: 5 years' experience at the Catholic University of Louvain
    C Wyns
    Department of Gynecology Andrology, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Avenue Hippocrate 10 B 1200, Brussels, Belgium
    Hum Reprod 26:737-47. 2011
    ..CONCLUSIONS The majority of cryopreserved samples showed reproductive potential. Storage was accepted by most parents. All parents and children considered this fertility preservation strategy a positive approach...
  44. pmc Is transplantation of cryopreserved ovarian tissue from patients with advanced-stage breast cancer safe? A pilot study
    V Luyckx
    Pôle de Recherche en Gynécologie, Institut de Recherche Expérimentale et Clinique, Universite Catholique de Louvain, Brussels, Belgium
    J Assist Reprod Genet 30:1289-99. 2013
    ..To assess the safety of reimplantation of cryopreserved ovarian tissue from advanced-stage breast cancer patients...
  45. ncbi request reprint Bladder endometriosis must be considered as bladder adenomyosis
    J Donnez
    Service de Gynecologie, Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Fertil Steril 74:1175-81. 2000
    ..To present data from a series of 17 cases of bladder endometriosis...
  46. ncbi request reprint Early-stage endometriosis: adhesion and growth of human menstrual endometrium in nude mice
    M Nisolle
    Infertility Department Research, Service de Gynecologie, Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Fertil Steril 74:306-12. 2000
    ..To evaluate the implantation of menstrual endometrium and the early stages of evolution of endometriotic lesions...
  47. ncbi request reprint GnRH agonist as novel luteal support: results of a randomized, parallel group, feasibility study using intranasal administration of buserelin
    C Pirard
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, B 1200 Brussels, Belgium
    Hum Reprod 20:1798-804. 2005
    ..The study objective was to investigate whether repeated intranasal administration of a GnRH agonist could provide convenient and safe luteal support...
  48. doi request reprint Ovarian tissue cryopreservation and transplantation in cancer patients
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, 1200 Brussels, Belgium
    Best Pract Res Clin Obstet Gynaecol 24:87-100. 2010
    ..This article reports the techniques and results of orthotopic transplantation of cryopreserved ovarian tissue. Among almost 30 cases reported in the literature, six live births have been achieved to date...
  49. ncbi request reprint Endometriosis is not only a gynecologic disease
    J Squifflet
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Acta Gastroenterol Belg 67:272-7. 2004
    ..Careful preoperative examination is mandatory (transrectal sonography, magnetic resonance imaging, bowel barium enema or intravenous pyelography) to evaluate potentially severe complications of the disease...
  50. doi request reprint [Animal models in endometriosis experimental research]
    S Colette
    Pôle de Recherche en Gynécologie, Département de gynécologie, Universite Catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires Saint Luc, Avenue Hippocrate 10, 1200 Bruxelles, Belgique
    Gynecol Obstet Fertil 40:494-6. 2012
    ..The present review looks at the different existing murine and non-human primate models of endometriosis, and evaluates their principal uses...
  51. ncbi request reprint Expression of receptors for insulin-like growth factor-I and transforming growth factor-beta in human follicles
    J Qu
    Laboratory of In Vitro Fertilization, Department of Gynecology, Hospital of Saint Luc, Catholic University of Louvain, Brussels, Belgium
    Mol Hum Reprod 6:137-45. 2000
    ..IGF-I and TGFbeta may be useful in regulating the in-vitro or in-vivo maturation of oocytes not only in later follicles but also very early follicles, from cryopreserved ovarian tissues for clinical use in the future...
  52. ncbi request reprint Laparoscopic myolysis
    J Donnez
    Département de gynécologie, Universite Catholique de Louvain, Cliniques Universitaires St Luc UCL, Brussels, Belgium
    Hum Reprod Update 6:609-13. 2000
    ....
  53. doi request reprint A series of 400 laparoscopic hysterectomies for benign disease: a single centre, single surgeon prospective study of complications confirming previous retrospective study
    O Donnez
    Department of Gynaecology, Universite Catholique de Louvain, Brussels, Belgium
    BJOG 117:752-5. 2010
    ..59% for major complications (n = 4) and 0% for minor complications, clearly confirming that laparoscopic hysterectomy is safe in experienced hands, especially in terms of urinary tract injuries...
  54. ncbi request reprint Predictive factors for multiple pregnancy in in vitro fertilization
    S Bassil
    Department of Gynecology, University Hospital St Luc, Catholic University of Louvain, Brussels, Belgium
    J Reprod Med 42:761-6. 1997
    ..To study predictive factors influencing the multiple pregnancy rate in in vitro fertilization (IVF)...
  55. ncbi request reprint Organochlorines and endometriosis: a mini-review
    Jean François Heilier
    Universite Catholique de Louvain, Faculty of Medicine, Industrial Toxicology and Occupational Medicine Unit, Brussels, Belgium
    Chemosphere 71:203-10. 2008
    ..The type of control women, the nature of the chemicals measured, and the definition of the disease could modulate the ability to detect the possible relationship between endometriosis and organochlorine exposure...
  56. doi request reprint Development and first in vivo trial of EvoLap, an active laparoscope positioner
    Benoît Herman
    Center for Research in Mechatronics, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Louvain la Neuve, Belgium
    J Minim Invasive Gynecol 16:344-9. 2009
    ..A first in vivo procedure demonstrated feasibility of the device and its value in clinical practice, enabling surgeons to work more comfortably...
  57. ncbi request reprint Serum dioxin-like compounds and aromatase (CYP19) expression in endometriotic tissues
    Jean François Heilier
    Universite Catholique de Louvain, Faculty of Medicine, Industrial Toxicology and Occupational Medicine Unit, 53 02 Avenue E Mounier, B 1200 Brussels, Belgium
    Toxicol Lett 167:238-44. 2006
    ..We conclude that DLCs do probably not facilitate the growth of endometriotic lesions by up-regulating the local expression of aromatase...
  58. ncbi request reprint Laparoscopic management of peritoneal endometriosis, endometriotic cysts, and rectovaginal adenomyosis
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Ann N Y Acad Sci 997:274-81. 2003
    ..In conclusion, peritoneal endometriosis, ovarian endometriosis, and rectovaginal adenomyotic nodules must be considered as three separate entities with different pathogeneses that require a different therapeutic approach...
  59. ncbi request reprint Environmental and host-associated risk factors in endometriosis and deep endometriotic nodules: a matched case-control study
    Jean François Heilier
    Industrial Toxicology and Occupational Medicine Unit, Universite Catholique de Louvain, 30 54 Clos Chapelle aux Champs B 1200 Brussels, Belgium
    Environ Res 103:121-9. 2007
    ..We conclude that PE and DEN share similar patterns of risk or protective factors...
  60. ncbi request reprint Expression of aromatase (P450 aromatase/CYP19) in peritoneal and ovarian endometriotic tissues and deep endometriotic (adenomyotic) nodules of the rectovaginal septum
    Jean François Heilier
    Industrial Toxicology and Occupational Medicine Unit, Universite Catholique de Louvain, Belgium
    Fertil Steril 85:1516-8. 2006
    ..Compared with peritoneal endometriosis, ovarian endometriosis exhibits an 8-fold higher expression of aromatase, which suggests that aromatase inhibitors may be particularly active in this form of endometriosis...
  61. ncbi request reprint Endometrial evaluation is a very important tool in the management of breast cancer patients
    M Berliere
    Department of Gynecology, St Luc Hospital Catholic University of Louvain, Avenue Hippocrate 10B 1200 Brussels, Belgium
    Eur J Cancer 38:S67-8. 2002
  62. ncbi request reprint Identification of novel antigens in blood vessels in rectovaginal endometriosis
    A van Langendonckt
    Department of Gynecology, Universite Catholique de Louvain, 1200 Brussels, Belgium
    Mol Hum Reprod 13:875-86. 2007
    ....
  63. ncbi request reprint Current thinking on the pathogenesis of endometriosis
    Jacques Donnez
    Department of Gynecology, Catholic University of Louvain, Cliniques Universitaires St Luc, Brussels, Belgium
    Gynecol Obstet Invest 54:52-8; discussion 59-62. 2002
    ....
  64. ncbi request reprint Surgical management of endometriosis
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Best Pract Res Clin Obstet Gynaecol 18:329-48. 2004
    ..In case of rectovaginal adenomyotic nodules, surgery must be considered as first-line therapy, medical therapy being relatively in-efficacious...
  65. ncbi request reprint Ureteral endometriosis: a complication of rectovaginal endometriotic (adenomyotic) nodules
    Jacques Donnez
    Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Service de Gynecologie, Brussels, Belgium
    Fertil Steril 77:32-7. 2002
    ..To present data from 18 cases of ureteral endometriosis...
  66. ncbi request reprint Preservation of fertility in young cancer patients: contribution of transmission electron microscopy
    Alessandra Camboni
    Department of Gynecology, Universite Catholique de Louvain, 1200 Brussels, Belgium
    Reprod Biomed Online 17:136-50. 2008
    ..Fine ultrastructural details highlighted by TEM studies will be useful for the further optimization of these emerging technologies...
  67. ncbi request reprint Efficacy of in vitro fertilization after chemotherapy
    Marie Madeleine Dolmans
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Fertil Steril 83:897-901. 2005
    ..To evaluate if in vitro fertilization (IVF) with embryo cryopreservation can be proposed to patients immediately after one or two regimens of chemotherapy...
  68. ncbi request reprint Ovarian tissue cryopreservation and transplantation: a review
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Hum Reprod Update 12:519-35. 2006
    ....
  69. ncbi request reprint Immunohistochemical study of the proliferation index, oestrogen receptors and progesterone receptors A and B in leiomyomata and normal myometrium during the menstrual cycle and under gonadotrophin-releasing hormone agonist therapy
    M Nisolle
    Infertility Research Unit, Service de Gynecologie, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate, 10, 1200 Bruxelles, Belgium
    Hum Reprod 14:2844-50. 1999
    ..The results suggest that leiomyomata may be under the influence of progesterone which may play a major role in their growth...
  70. ncbi request reprint Goserelin acetate (Zoladex) plus endometrial ablation for dysfunctional uterine bleeding: a 3-year follow-up evaluation
    J Donnez
    Department of Gynaecology, University Hospital Saint-Luc, Brussels, Belgium
    Fertil Steril 75:620-2. 2001
    ..6% for the goserelin acetate group and 2.1% for the control group. CONCLUSION(S): Prethinning with goserelin acetate before endometrial ablation resulted in higher long-term amenorrhea rates than ablation without prethinning...
  71. ncbi request reprint Cadmium, lead and endometriosis
    J F Heilier
    Industrial Toxicology and Occupational Medicine Unit, Faculty of Medicine, Universite Catholique de Louvain, 30 54 Clos Chapelle aux Champs, 1200, Brussels, Belgium
    Int Arch Occup Environ Health 80:149-53. 2006
    ..Cadmium (Cd) and lead (Pb) have been demonstrated to exert endocrine disrupting activities. Their possible role in endometriosis, an oestrogen-dependent disease, is unknown...
  72. doi request reprint Potential involvement of iron in the pathogenesis of peritoneal endometriosis
    S Defrere
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Mol Hum Reprod 14:377-85. 2008
    ..Treatment with an iron chelator could thus be beneficial in endometriosis patients to prevent iron overload in the pelvic cavity, thereby diminishing its deleterious effect...
  73. ncbi request reprint Diagnosis and imaging of adenomyotic disease of the retroperitoneal space
    Jean Squifflet
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Brussels, Belgium
    Gynecol Obstet Invest 54:43-51. 2002
    ..This anatomical classification based on clinical examination and imaging will allow us in the future to define the most appropriate treatment for each entity...
  74. ncbi request reprint Pre- and post-surgical management of endometriosis
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Semin Reprod Med 21:235-42. 2003
    ..In cases of rectovaginal adenomyotic nodule, surgery must be considered as first-line therapy, medical therapy being relatively inefficacious...
  75. ncbi request reprint Laparoscopic excision of deep endometriosis
    Jacques Donnez
    Department of Gynecology, Catholic University of Louvain, Cliniques Universitaires Saint Luc, Avenue Hippocrate 10, Brussels 1200, Belgium
    Obstet Gynecol Clin North Am 31:567-80, ix. 2004
    ..This article reviews the classification, the diagnosis, and the surgical treatment of deep endometriosis (adenomyotic disease)...
  76. doi request reprint IVF outcome in patients with orthotopically transplanted ovarian tissue
    Marie Madeleine Dolmans
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate, 10 B 1200 Brussels, Belgium
    Hum Reprod 24:2778-87. 2009
    ..Our aim was to evaluate the quality of oocytes and embryos derived from frozen-thawed transplanted ovarian tissue...
  77. ncbi request reprint Posthysterectomy pelvic adenomyotic masses observed in 8 cases out of a series of 1405 laparoscopic subtotal hysterectomies
    Olivier Donnez
    Department of Gynecology, Cliniques Universitaires Saint Luc, Brussels, Belgium
    J Minim Invasive Gynecol 14:156-60. 2007
    ..To analyze the prevalence of an unexpected complication due to morcellation and to describe the appearance of this complication on magnetic resonance imaging, as well as its therapy...
  78. ncbi request reprint The role of cryopreservation for women prior to treatment of malignancy
    Jacques Donnez
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate, 10, B 1200 Brussels, Belgium
    Curr Opin Obstet Gynecol 17:333-8. 2005
    ..The purpose of this review is to investigate recent advances in xenografting, as well as in orthotopic and heterotopic autotransplantation of human cryopreserved ovarian tissue...
  79. ncbi request reprint Laparoscopic ovariectomy for whole human ovary cryopreservation: technical aspects
    Pascale Jadoul
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Fertil Steril 87:971-5. 2007
    ..To describe the technique of laparoscopic ovariectomy with a view to cryopreservation of a whole ovary with its vascular pedicle...
  80. doi request reprint Options for fertility preservation in prepubertal boys
    Christine Wyns
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Avenue Hippocrate 10, Brussels, Belgium
    Hum Reprod Update 16:312-28. 2010
    ..This paper covers current options for ITT cryopreservation and fertility restoration...
  81. ncbi request reprint Freeze-thawing intact human ovary with its vascular pedicle with a passive cooling device
    Belen Martinez-Madrid
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 82:1390-4. 2004
    ..To test the feasibility of freezing intact human ovary using a passive cooling device...
  82. ncbi request reprint The efficacy of medical and surgical treatment of endometriosis-associated infertility: arguments in favour of a medico-surgical aproach
    Jacques Donnez
    Department of Gynaecology, Universite Catholique de Louvain, Brussels, Belgium
    Hum Reprod Update 8:89-94. 2002
    ..In moderate and severe endometriosis, this review provides arguments in favour of a medico-surgical approach and discusses the possibility of combining medical and surgical therapy...
  83. ncbi request reprint Apoptosis and ultrastructural assessment after cryopreservation of whole human ovaries with their vascular pedicle
    Belen Martinez-Madrid
    Department of Gynecology, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 87:1153-65. 2007
    ..To investigate possible damage caused by freeze-thawing whole human ovaries...
  84. ncbi request reprint Increased dioxin-like compounds in the serum of women with peritoneal endometriosis and deep endometriotic (adenomyotic) nodules
    Jean François Heilier
    Industrial Toxicology and Occupational Medicine Unit, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 84:305-12. 2005
    ..To investigate the possible association between the body burden of dioxin-like compounds and endometriotic disease...
  85. ncbi request reprint Taking a history in the evaluation of infertility: obsolete or venerable tradition?
    Jacques Donnez
    Universite Catholique de Louvain, Cliniques Universitaires St Luc, Department of Gynecology, Brussels, Belgium
    Fertil Steril 81:16-7; discussion 18. 2004
    ..Taking a relevant history that includes pelvic inflammatory disease or exposure to sexually transmitted diseases is not obsolete...
  86. ncbi request reprint Ascites and pelvic masses: an unusual case of endometriosis
    Jacques Donnez
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Brussels, Belgium
    Fertil Steril 83:195-7. 2005
    ..We describe an unusual case of ascites caused by the rupture of a large endometrioma...
  87. doi request reprint Reimplantation of cryopreserved ovarian tissue from patients with acute lymphoblastic leukemia is potentially unsafe
    Marie Madeleine Dolmans
    Department of Gynecology, GYNE Research Unit, Institut de Recherche Expérimentale et Clinique, Universite Catholique de Louvain, Brussels, Belgium
    Blood 116:2908-14. 2010
    ..Moreover, chemotherapy before ovarian cryopreservation does not exclude malignant contamination. Finally, reimplantation of cryopreserved ovarian tissue from ALL and CML patients puts them at risk of disease recurrence...
  88. ncbi request reprint Assessment of cadmium impregnation in women suffering from endometriosis: a preliminary study
    Jean François Heilier
    Industrial Toxicology and Occupational Medicine Unit, Faculty of Medicine, Universite Catholique de Louvain, 30 54 Clos Chapelle aux Champs, B 1200 Brussels, Belgium
    Toxicol Lett 154:89-93. 2004
    ..These data, therefore, do not support a role for cadmium in the onset or the growth of endometriosis or deep endometriotic (adenomyotic) nodules of the recto-vaginal septum...
  89. ncbi request reprint Typical and subtle atypical presentations of endometriosis
    Jacques Donnez
    Department of Gynecology, St Luc s Hospital, Universite Catholique de Louvain, Avenue Hippocrate, 1200 Brussels, Belgium
    Obstet Gynecol Clin North Am 30:83-93, viii. 2003
    ..Red flame-like lesions, glandular excrescences, and subovarian adhesions must be considered as the most active lesions. Sometimes, however, subtle endometriotic lesions can be the only lesions seen at laparoscopy...
  90. ncbi request reprint Safety of conservative management and fertility outcome in women with borderline tumors of the ovary
    Jacques Donnez
    Department of Gynecology, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 79:1216-21. 2003
    ..To assess the safety of fertility-sparing treatment and the remaining chance of childbearing after surgery...
  91. doi request reprint Unusual complication after uterine artery embolization and laparoscopic myomectomy in a woman wishing to preserve future fertility
    Olivier Donnez
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 90:2007.e5-9. 2008
    ..To report a case of uterine fistula arising after laparoscopic myomectomy after a uterine artery embolization...
  92. doi request reprint Survival of human pre-antral follicles after cryopreservation of ovarian tissue, follicular isolation and in vitro culture in a calcium alginate matrix
    Christiani A Amorim
    Department of Gynecology, Universite Catholique de Louvain, Avenue Emmanuel Mounier 52, bte 5247, 1200 Brussels, Belgium
    Hum Reprod 24:92-9. 2009
    ..On the basis of this assumption, the aim of our study was to investigate in vitro survival and growth of pre-antral follicles after cryopreservation of ovarian tissue and follicular isolation, followed by encapsulation in alginate beads...
  93. doi request reprint Laparoscopic observation of spontaneous human ovulation
    Jean Christophe Lousse
    Department of Gynecology, Universite Catholique de Louvain, 1200 Brussels, Belgium
    Fertil Steril 90:833-4. 2008
    ..We report laparoscopic observation of spontaneous human ovulation, illustrated by protrusion of the mature follicle and oocyte release into the peritoneal cavity...
  94. ncbi request reprint Equivalence of the 3-month and 28-day formulations of triptorelin with regard to achievement and maintenance of medical castration in women with endometriosis
    Jacques Donnez
    Department of Gynecology and Andrology, Universite Catholique de Louvain, Service de Gynecologie, Brussels, Belgium
    Fertil Steril 81:297-304. 2004
    ....
  95. ncbi request reprint Restoration of ovarian function in orthotopically transplanted cryopreserved ovarian tissue: a pilot experience
    Jacques Donnez
    Department of Gynecology, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate, 10, B 1200 Brussels, Belgium
    Reprod Biomed Online 16:694-704. 2008
    ..Grafts remained functional in all the women. Transplantation of cryopreserved ovarian tissue to an orthotopic site appears to restore ovarian endocrine function, without any signs of disease recurrence...
  96. ncbi request reprint Combined laparoscopic and vaginal approach for nephrectomy, ureterectomy, and removal of a large rectovaginal endometriotic nodule causing loss of renal function
    Pascale Jadoul
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    J Minim Invasive Gynecol 14:256-9. 2007
    ..By means of a case report, this paper describes the combination of laparoscopic nephrectomy, ureterectomy, removal of the rectovaginal endometriotic nodule, and extraction of the kidney through the vagina...
  97. doi request reprint Chick embryo chorioallantoic membrane (CAM) model: a useful tool to study short-term transplantation of cryopreserved human ovarian tissue
    Belen Martinez-Madrid
    Department of Gynecology, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 91:285-92. 2009
    ..To investigate the chorioallantoic membrane (CAM) model for the study of short-term transplantation of frozen human ovarian tissue...
  98. doi request reprint Both host and graft vessels contribute to revascularization of xenografted human ovarian tissue in a murine model
    Anne Sophie Van Eyck
    Department of Gynecology, Universite Catholique de Louvain, 1200 Brussels, Belgium
    Fertil Steril 93:1676-85. 2010
    ..To characterize the human ovarian xenograft revascularization process...
  99. ncbi request reprint Autotransplantation of frozen-thawed ovarian tissue in a young woman: ultrastructure and viability of grafted tissue
    Alessandra Camboni
    Department of Gynecology, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Brussels, Belgium
    Fertil Steril 90:1215-8. 2008
    ..The stroma contained numerous viable and ultrastructurally normal blood vessels but showed poor cellular density...
  100. ncbi request reprint Primary ovarian adenocarcinoma developing in ovarian remnant tissue ten years after laparoscopic hysterectomy and bilateral salpingo-oophorectomy for endometriosis
    Olivier Donnez
    Department of Gynecology, Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Brussels, Belgium
    J Minim Invasive Gynecol 14:752-7. 2007
    ..We discuss the management of pelvic masses suspected of malignancy after bilateral salpingo-oophorectomy and the possible role of endometriosis in the development of malignancy in ovarian remnant syndrome...
  101. ncbi request reprint Quantification of endometriotic lesions in a murine model by fluorimetric and morphometric analyses
    Sylvie Defrere
    Department of Gynaecology, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    Hum Reprod 21:810-7. 2006
    ..The purpose of the present study was to develop two new methods of quantifying endometriosis-like lesions in a nude mouse model: fluorimetry and morphometry...