Philippe Van der Linden

Summary

Affiliation: CHU Brugmann
Country: Belgium

Publications

  1. doi request reprint Sedation in gastrointestinal endoscopy: an anesthesiologist's perspective
    Philippe Van der Linden
    Department of Anesthesiology, CHU Brugmann HUDERF, Free University of Brussels, Brussels, Belgium
    Digestion 82:102-5. 2010
  2. ncbi request reprint Tolerance to acute isovolemic hemodilution. Effect of anesthetic depth
    Philippe Van der Linden
    Department of Cardiac Anesthesia, CHU Charleroi, Belgium
    Anesthesiology 99:97-104. 2003
  3. ncbi request reprint 3.5% urea-linked gelatin is as effective as 6% HES 200/0.5 for volume management in cardiac surgery patients
    Philippe J Van der Linden
    Department of Cardiac Anesthesia, CHU Charleroi, Charleroi, Belgium
    Can J Anaesth 51:236-41. 2004
  4. ncbi request reprint Hydroxyethyl starch 130/0.4 versus modified fluid gelatin for volume expansion in cardiac surgery patients: the effects on perioperative bleeding and transfusion needs
    Philippe J Van der Linden
    Department of Anesthesiology, CHU Brugmann HUDERF, 4 Place Van Gehuchten, B 1020 Brussels, Belgium
    Anesth Analg 101:629-34, table of contents. 2005
  5. ncbi request reprint Blood conservation strategies in cardiac surgery
    P Van der Linden
    Department of Anaesthesiology, CHU Brugmann HUDERF, Free University of Brussels, 4 Place Van Gehuchten, B 1020 Brussels, Belgium
    Vox Sang 92:103-12. 2007
  6. pmc Efficacy and safety of 6% hydroxyethyl starch 130/0.4 (Voluven) for perioperative volume replacement in children undergoing cardiac surgery: a propensity-matched analysis
    Philippe Van der Linden
    Department of Anesthesiology, University Hospital Brugmann and Queen Fabiola Children s University Hospital, Free University of Brussels, 4 Place Van Gehuchten, B 1020, Brussels, Belgium
    Crit Care 19:87. 2015
  7. ncbi request reprint A systematic review of antifibrinolytics and massive injury
    D Faraoni
    Department of Anesthesiology, Centre Hospitalier Universitaire CHU Brugmann Queen Fabiola Children s University Hospital QFCUH, Brussels, Belgium
    Minerva Anestesiol 80:1115-22. 2014
  8. pmc Transfusion trigger in critically ill patients: has the puzzle been completed?
    Eric Reiles
    Department of Anesthesiology Centre, Hospitalo Unversitaire CHU Brugmann and Hôpital Universitaire des Enfants Reine Fabiola HUDERF, Place Van Gehuchten, B 1020, Brussels, Belgium
    Crit Care 11:142. 2007
  9. ncbi request reprint Recommendations in the event of a suspected transfusion-related acute lung injury (TRALI)
    P Van der Linden
    Service d anesthésiologie, CHU Brugmann HUDERF, Universite Libre de Bruxelles ULB, Belgium
    Acta Clin Belg 67:201-8. 2012
  10. ncbi request reprint The effects of colloid solutions on hemostasis
    Philippe Van der Linden
    Department of Anesthesiology, CHU Brugmann HUDERF, 4 Place Van Gehuchten, B 1020 Brussels, Belgium
    Can J Anaesth 53:S30-9. 2006

Collaborators

Detail Information

Publications31

  1. doi request reprint Sedation in gastrointestinal endoscopy: an anesthesiologist's perspective
    Philippe Van der Linden
    Department of Anesthesiology, CHU Brugmann HUDERF, Free University of Brussels, Brussels, Belgium
    Digestion 82:102-5. 2010
    ..Although further evaluation is needed, computer-assisted systems might contribute to the safe administration of propofol through a better control of the level of sedation...
  2. ncbi request reprint Tolerance to acute isovolemic hemodilution. Effect of anesthetic depth
    Philippe Van der Linden
    Department of Cardiac Anesthesia, CHU Charleroi, Belgium
    Anesthesiology 99:97-104. 2003
    ..Anesthetic agents with negative effects on the cardiovascular system may exert proportionately greater depressant effects on cardiac output response than on tissue oxygen demand, reducing tolerance to acute isovolemic anemia...
  3. ncbi request reprint 3.5% urea-linked gelatin is as effective as 6% HES 200/0.5 for volume management in cardiac surgery patients
    Philippe J Van der Linden
    Department of Cardiac Anesthesia, CHU Charleroi, Charleroi, Belgium
    Can J Anaesth 51:236-41. 2004
    ..5% gelatin and 6% hydroxyethyl starch 200/0.5 in patients undergoing cardiac surgery. The second objective was to compare the two colloids in terms of blood losses and allogeneic blood transfusion exposure rate...
  4. ncbi request reprint Hydroxyethyl starch 130/0.4 versus modified fluid gelatin for volume expansion in cardiac surgery patients: the effects on perioperative bleeding and transfusion needs
    Philippe J Van der Linden
    Department of Anesthesiology, CHU Brugmann HUDERF, 4 Place Van Gehuchten, B 1020 Brussels, Belgium
    Anesth Analg 101:629-34, table of contents. 2005
    ..In the conditions of the present study, HES 130/0.4 up to 50 mL/kg is a valuable alternative to modified fluid gelatin for plasma volume expansion during and after cardiac surgery...
  5. ncbi request reprint Blood conservation strategies in cardiac surgery
    P Van der Linden
    Department of Anaesthesiology, CHU Brugmann HUDERF, Free University of Brussels, 4 Place Van Gehuchten, B 1020 Brussels, Belgium
    Vox Sang 92:103-12. 2007
    ..It implies the establishment of a reliable system, collecting data both at the surgical team and at the medical level...
  6. pmc Efficacy and safety of 6% hydroxyethyl starch 130/0.4 (Voluven) for perioperative volume replacement in children undergoing cardiac surgery: a propensity-matched analysis
    Philippe Van der Linden
    Department of Anesthesiology, University Hospital Brugmann and Queen Fabiola Children s University Hospital, Free University of Brussels, 4 Place Van Gehuchten, B 1020, Brussels, Belgium
    Crit Care 19:87. 2015
    ..In this large propensity-matched analysis, we aimed to assess the efficacy and safety of replacing HA with HES for intraoperative volume therapy in children undergoing cardiac surgery with cardiopulmonary bypass (CPB)...
  7. ncbi request reprint A systematic review of antifibrinolytics and massive injury
    D Faraoni
    Department of Anesthesiology, Centre Hospitalier Universitaire CHU Brugmann Queen Fabiola Children s University Hospital QFCUH, Brussels, Belgium
    Minerva Anestesiol 80:1115-22. 2014
    ..For this reason, further studies are needed to better define the "optimal" dose scheme based on pharmacokinetic and pharmacodynamic studies. ..
  8. pmc Transfusion trigger in critically ill patients: has the puzzle been completed?
    Eric Reiles
    Department of Anesthesiology Centre, Hospitalo Unversitaire CHU Brugmann and Hôpital Universitaire des Enfants Reine Fabiola HUDERF, Place Van Gehuchten, B 1020, Brussels, Belgium
    Crit Care 11:142. 2007
    ..Further research should compare a symptomatic transfusion strategy to a hemoglobin-based strategy on the outcome of high risk patients...
  9. ncbi request reprint Recommendations in the event of a suspected transfusion-related acute lung injury (TRALI)
    P Van der Linden
    Service d anesthésiologie, CHU Brugmann HUDERF, Universite Libre de Bruxelles ULB, Belgium
    Acta Clin Belg 67:201-8. 2012
    ..The clinician should pay very close attention to any change in the patient's respiratory status (cf. dyspnoea and arterial desaturation), which should be notified systematically to the haemovigilance contact person in the hospital...
  10. ncbi request reprint The effects of colloid solutions on hemostasis
    Philippe Van der Linden
    Department of Anesthesiology, CHU Brugmann HUDERF, 4 Place Van Gehuchten, B 1020 Brussels, Belgium
    Can J Anaesth 53:S30-9. 2006
    ..Although more efficacious than crystalloids, they are more expensive and can be associated with adverse effects, in particular when they interfere with the hemostatic system...
  11. doi request reprint Efficacy of tranexamic acid in paediatric cardiac surgery: a systematic review and meta-analysis
    David Faraoni
    Department of Anaesthesiology, Centre Hospitalier Universitaire, Brugmann HUDERF, Brussels, Belgium
    Eur J Cardiothorac Surg 42:781-6. 2012
    ..Evidence supporting the routine use of TXA in paediatric cardiac surgery remains weak...
  12. doi request reprint Perioperative volume replacement in children undergoing cardiac surgery: albumin versus hydroxyethyl starch 130/0.4
    Christophe Hanart
    Department of Anesthesiology, CHU Brugmann HUDERF, Brussels, Belgium
    Crit Care Med 37:696-701. 2009
    ..To compare 4% albumin with 6% hydroxyethyl starch (HES) 130/0.4 in terms of perioperative blood loss and intraoperative fluid requirements in children undergoing cardiac surgery...
  13. doi request reprint The indication for perioperative red blood cell transfusions is a predictive risk factor for severe postoperative morbidity and mortality in children undergoing cardiac surgery
    Ariane Willems
    Paediatric Intensive Care Unit, Department of Paediatrics, University Children s Hospital Queen Fabiola, Brussels, Belgium
    Eur J Cardiothorac Surg 45:1050-7. 2014
    ..Sometimes, RBCs are added to the prime solution to avoid a too low haematocrit on bypass (CPB-driven transfusion). Our study investigated whether the reason for RBC transfusion might affect severe postoperative morbidity or mortality...
  14. doi request reprint Continuous mixed venous and central venous oxygen saturation in cardiac surgery with cardiopulmonary bypass
    Pierre Yves Lequeux
    Department of Anesthesiology, Intensive Care Unit, CHU Tivoli, La Louviere, Belgium
    Eur J Anaesthesiol 27:295-9. 2010
    ..The influence of surgery, cardiopulmonary bypass and anaesthesia drugs on the relationship between SvO2 and ScvO2 has never been studied...
  15. doi request reprint Experimental model of hyperfibrinolysis designed for rotational thromboelastometry in children with congenital heart disease
    David Faraoni
    aDepartment of Anesthesiology, Queen Fabiola Children s University Hospital, Brugmann University Hospital, Free University of Brussels, Brussels, Belgium bDepartment of Anesthesia, Peri operative and Pain Medicine, Boston Children s Hospital, Boston, Massachusetts, USA cDepartment of Hematology and Hemostasis, Queen Fabiola Children s University Hospital, Brugmann University Hospital, Free University of Brussels dDepartment of Pediatric Intensive Care, Queen Fabiola Children s University Hospital, Free University of Brussels, Brussels, Belgium
    Blood Coagul Fibrinolysis 26:290-7. 2015
    ..In addition, we observed that LOT and LI30 should be considered as the best parameters to detect different degrees of fibrinolysis. ..
  16. doi request reprint Plasma fibrinogen concentration is correlated with postoperative blood loss in children undergoing cardiac surgery. A retrospective review
    David Faraoni
    From the Department of Anaesthesiology, Centre Hospitalier Universitaire Brugmann Queen Fabiola Children s University Hospital, Free University of Brussels DF, ADV, PVdL, Paediatric Intensive Care Unit, Queen Fabiola Children s University Hospital, Brussels, Belgium AW, Department of Anaesthesia and Intensive Care, International Hospital Medpark, Chisinau, Republic of Moldova VS, and Department of Cardiac Surgery, Centre Hospitalier Universitaire Brugmann Queen Fabiola Children s University Hospital, Free University of Brussels, Brussels, Belgium HD
    Eur J Anaesthesiol 31:317-26. 2014
    ..Fibrinogen supplementation is increasingly recommended with the use of rotational thromboelastometry (ROTEM). However, data regarding the paediatric population are sparse...
  17. ncbi request reprint Efficacy of allogeneic red blood cell transfusions
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
    Best Pract Res Clin Anaesthesiol 21:209-19. 2007
    ..In this article, several key factors influencing the systemic and regional efficacy of blood transfusion will be reviewed...
  18. doi request reprint Hemodilution and anemia in patients with cardiac disease: what is the safe limit?
    Robert Tircoveanu
    Department of Anesthesiology, Free University of Brussels, Brussels, Belgium
    Curr Opin Anaesthesiol 21:66-70. 2008
    ..Although blood transfusions are commonly used in these patients, there is little evidence that such an approach improved patients' clinical outcome...
  19. doi request reprint A double-blind, randomized, multicenter study of MP4OX for treatment of perioperative hypotension in patients undergoing primary hip arthroplasty under spinal anesthesia
    Philippe Van der Linden
    Department of Anesthesiology, CHU Brugmann, Brussels, Belgium
    Anesth Analg 112:759-73. 2011
    ..In this study, we investigated the ability of MP4OX to treat hypotensive episodes. In addition, the tolerability profile of MP4OX in a large surgical population was established...
  20. doi request reprint Evaluation of dynamic parameters of thrombus formation measured on whole blood using rotational thromboelastometry in children undergoing cardiac surgery: a descriptive study
    David Faraoni
    Department of Anaesthesiology, Centre Hospitalier Universitaire Brugmann Queen Fabiola Children s University Hospital, Free University of Brussels, Brussels, Belgium Department of Anesthesiology, Peri operative and Pain Medicine, Boston Children s Hospital, Harvard Medical School, Boston, MA, USA
    Paediatr Anaesth 25:573-9. 2015
    ....
  21. doi request reprint Development of a specific algorithm to guide haemostatic therapy in children undergoing cardiac surgery: A single-centre retrospective study
    David Faraoni
    From the Department of Anaesthesiology, Queen Fabiola Children s University Hospital Centre Hospitalier Universitaire Brugmann DF, VDL, Paediatric Intensive Care Unit, Queen Fabiola Children s University Hospital, Free University of Brussels, Brussels, Belgium AW, Department of Paediatric Anaesthesia and Intensive Care, Queen Silvia s Children Hospital, Gothenburg, Sweden BSR and Department of Anaesthesiology, Centre Hospitalier de l Universite de Montreal CHUM, Montreal, Quebec, Canada SB
    Eur J Anaesthesiol 32:320-9. 2015
    ..Although rotational thromboelastometry (ROTEM) is increasingly used to guide haemostatic therapy in a bleeding patient, there is a paucity of data guiding its use in the paediatric population...
  22. doi request reprint Predictive factors for red blood cell transfusion in children undergoing noncomplex cardiac surgery
    Muj Mulaj
    Department of Anesthesiology, Centre Hospitalier Universitaire Brugmann and Queen Fabiola Children s University Hospital, Brussels, Belgium
    Ann Thorac Surg 98:662-7. 2014
    ..This study aimed to assess predictive factors associated with RBC transfusion in children undergoing low-risk cardiac surgery with cardiopulmonary bypass (CPB)...
  23. ncbi request reprint Perioperative blood conservation strategies: an update for clinicians
    Philippe Van der Linden
    Department of Cardiac Anesthesia, C H U Charleroi, Belgium
    Can J Anaesth 50:S1-2. 2003
  24. pmc Factors affecting postoperative blood loss in children undergoing cardiac surgery
    David Faraoni
    Department of Anesthesiology, Centre Hospitalier Universitaire CHU Brugmann Queen Fabiola Children s University Hospital QFCUH, Free University of Brussels, 15 JJ Crocq Av, 1020, Brussels, Belgium
    J Cardiothorac Surg 9:32. 2014
    ..Additional studies are needed to define optimal pathophysiology-based management in children undergoing cardiac surgery...
  25. doi request reprint Impact of entropy monitoring on volatile anesthetic uptake
    Tarek El Hor
    Department of Anesthesiology, University Hospital Center of Brugmann, Free University of Brussels, Brussels, Belgium
    Anesthesiology 118:868-73. 2013
    ..The authors hypothesized that the use of M-Entropy monitoring (Datex-Ohmeda, Helsinki, Finland) is associated with reduced sevoflurane uptake (primary outcome) in patients undergoing major abdominal surgery...
  26. ncbi request reprint Acute normovolemic hemodilution: physiology, limitations, and clinical use
    Marina Jamnicki
    Institute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland
    J Cardiothorac Vasc Anesth 17:747-54. 2003
  27. ncbi request reprint The effects of acute isovolemic hemodilution on oxygenation during one-lung ventilation
    Laszlo L Szegedi
    Department of Anesthesiology 2K12, Gent University Hospital, De Pintelaan, 185, 9000 Gent, Belgium
    Anesth Analg 100:15-20. 2005
    ..01). Mild IH impairs gas exchange during OLV in COPD patients, but not in patients with normal lung function...
  28. doi request reprint The effects of hydroxyethyl starch 130/0.4 (6%) on blood loss and use of blood products in major surgery: a pooled analysis of randomized clinical trials
    Sibylle A Kozek-Langenecker
    Department of Special Anesthesiology and Pain Management, Vienna Medical University, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Anesth Analg 107:382-90. 2008
    ..To test this hypothesis, we analyzed pooled data from all available studies in major surgery comparing 6% HES 130/0.4 and 6% HES 200/0.5 from waxy maize starch...
  29. ncbi request reprint [Normovolemic hemodilution and the heart]
    Philippe Van der Linden
    Can J Anaesth 52:130-2. 2005
  30. ncbi request reprint Blood conservation and the management of perioperative blood transfusions in a patient undergoing major vascular surgery: a Self-Assessment Program
    Jean François Hardy
    University of Montreal, Montreal, Canada
    Can J Anaesth 52:344-5. 2005
  31. doi request reprint Efficacy and safety of recombinant activated factor VII to control bleeding in nonhemophiliac patients: a review of 17 randomized controlled trials
    Jean François Hardy
    Department of Anesthesiology, University of Montreal, Quebec, Canada
    Ann Thorac Surg 86:1038-48. 2008
    ..In addition, the safety of rFVIIa remains a concern. Consequently, we conclude that the generalized use of rFVIIa to prevent or to control bleeding in nonhemophiliac patients can not be recommended...