Luc Bertrand

Summary

Country: Belgium

Publications

  1. Beauloye C, Horman S, Bertrand L. Even is better than odd: one fat may conceal another. Am J Physiol Heart Circ Physiol. 2015;309:H1112-4 pubmed publisher
  2. Mailleux F, Gélinas R, Beauloye C, Horman S, Bertrand L. O-GlcNAcylation, enemy or ally during cardiac hypertrophy development?. Biochim Biophys Acta. 2016;1862:2232-2243 pubmed publisher
    ..This article is part of a Special Issue entitled: The role of post-translational protein modifications on heart and vascular metabolism edited by Jason R.B. Dyck & Jan F.C. Glatz. ..
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    Angin Y, Beauloye C, Horman S, Bertrand L. Regulation of Carbohydrate Metabolism, Lipid Metabolism, and Protein Metabolism by AMPK. Exp Suppl. 2016;107:23-43 pubmed
    ..AMPK mainly promotes glucose and fatty acid catabolism, whereas it prevents protein, glycogen, and fatty acid synthesis. ..
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    Daskalopoulos E, Dufeys C, Beauloye C, Bertrand L, Horman S. AMPK in Cardiovascular Diseases. Exp Suppl. 2016;107:179-201 pubmed
  5. Mailleux F, Beauloye C, Balligand J, Horman S, Bertrand L. Studying the Role of AMPK in Cardiac Hypertrophy and Protein Synthesis. Methods Mol Biol. 2018;1732:321-342 pubmed publisher
    ..Two different compounds, AICAr and the biguanide phenformin, were used to promote AMPK activation. ..
  6. Timmermans A, Balteau M, Gélinas R, Renguet E, Ginion A, de Meester C, et al. A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake. Am J Physiol Heart Circ Physiol. 2014;306:H1619-30 pubmed publisher
    ..However, strikingly, its ability of potentiating the action on other AMPK activators makes it a potentially useful participant in the protective role of AMPK in the heart. ..
  7. Renguet E, Ginion A, Gélinas R, Bultot L, Auquier J, Robillard Frayne I, et al. Metabolism and acetylation contribute to leucine-mediated inhibition of cardiac glucose uptake. Am J Physiol Heart Circ Physiol. 2017;313:H432-H445 pubmed publisher
    ..Listen to this article's corresponding podcast at http://ajpheart.podbean.com/e/leucine-metabolism-inhibits-cardiac-glucose-uptake/. ..
  8. Gélinas R, Mailleux F, Dontaine J, Bultot L, Demeulder B, Ginion A, et al. AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation. Nat Commun. 2018;9:374 pubmed publisher
    ..We conclude that AMPK activation prevents cardiac hypertrophy predominantly by inhibiting O-GlcNAcylation. ..