Eric J Bellefroid
Desmaris E, Keruzore M, Saulnier A, Ratié L, Assimacopoulos S, De Clercq S, et al
. DMRT5, DMRT3, and EMX2 Cooperatively Repress Gsx2 at the Pallium-Subpallium Boundary to Maintain Cortical Identity in Dorsal Telencephalic Progenitors. J Neurosci. 2018;38:9105-9121 pubmed publisher
..Our study suggests that DMRT3/5 function with EMX2 in positioning the pallial-subpallial boundary by antagonizing the ventral homeobox transcription factor GSX2. ..
ThÃ©lie A, Desiderio S, Hanotel J, Quigley I, Van Driessche B, Rodari A, et al
. Prdm12 specifies V1 interneurons through cross-repressive interactions with Dbx1 and Nkx6 genes in Xenopus. Development. 2015;142:3416-28 pubmed publisher
Muralidharan B, Keruzore M, Pradhan S, Roy B, Shetty A, Kinare V, et al
. Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control the Neuron-Glia Cell-Fate Switch in the Developing Hippocampus. J Neurosci. 2017;37:11245-11254 pubmed publisher
..Our findings uncover a complex network that involves Lhx2, Dmrt5, Neurog2, and Pax6, and that ensures the appropriate amount and timing of neurogenesis and gliogenesis in the developing hippocampus. ..
Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, et al
. Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019;26:3522-3536.e5 pubmed publisher
..Altogether, our results identify Prdm12 as an evolutionarily conserved key regulator of nociceptor specification and as an actionable target for new pain therapeutics. ..
Bessodes N, Parain K, Bronchain O, Bellefroid E, Perron M. Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina. Neural Dev. 2017;12:16 pubmed publisher
..We also reveal that Prdm13 regulates ptf1a expression through a negative feedback loop. ..