Research Topics
| Filip BaertSummaryCountry: Belgium Publications
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Detail Information
Publications
Adalimumab dose escalation and dose de-escalation success rate and predictors in a large national cohort of Crohn's patientsFilip Baert
Department of Internal Medicine, H Hart ziekenhuis Roeselare Menen, Belgium
J Crohns Colitis 7:154-60. 2013..Attempts for dose de-escalation have not been studied. This study aimed to assess the need for, predictors, and outcome of dose escalation and de-escalation in a large cohort of adalimumab treated Crohn's patients...
Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's diseaseFilip Baert
Department of Gastroenterology, H Hartziekenhuis Roeselare Menen vzw, Roeselare, Belgium
Gastroenterology 138:463-8; quiz e10-1. 2010..Few prospective data are available to support the clinical relevance of mucosal healing in patients with Crohn's disease. This study examined whether complete healing, determined by endoscopy, predicts a better outcome in Crohn's disease...
Epidermal growth factor receptor and K-RAS status in two cohorts of squamous cell carcinomasNancy Van Damme
Department of Hepato Gastroenterology, Digestive Oncology Unit, Ghent University Hospital, De Pintelaan 185 1K12IE, 9000 Ghent, Belgium
BMC Cancer 10:189. 2010..The aim of this study was to analyse EGFR expression, EGFR gene copy number and EGFR and K-RAS mutations in two cohorts of squamous cell carcinomas, specifically anal canal and tonsil carcinomas...
Efficacy of infliximab in refractory pouchitis and Crohn's disease-related complications of the pouch: a Belgian case seriesMarc Ferrante
Department of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
Inflamm Bowel Dis 16:243-9. 2010..In case reports, thiopurine analogs and infliximab (IFX) have been proposed as effective therapy in this setting. We analyzed the long-term efficacy of IFX in Belgian patients with refractory pouch complications...
Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's diseaseSeverine Vermeire
Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
Gut 56:1226-31. 2007..Concomitant use of immunosuppressives (IS) reduces the risk of ATI formation...
Medical therapy for Crohn's disease: top-down or step-up?Filip Baert
Department of Gastroenterology, Hospital of Leuven, Belgium
Dig Dis 25:260-6. 2007..Lack of markers able to identify high-risk patients, discussions about long-term safety and the high costs of infliximab are further factors supporting a more careful approach to the management of CD...
Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trialPaul Rutgeerts
Department of Gastroenterology, University Hospital Gasthuisberg, 3000 Leuven, Belgium
Gastroenterology 128:856-61. 2005..We investigated the efficacy and safety of ornidazole, a nitroimidazole antibiotic, for the prevention of clinical recurrence of Crohn's disease after curative ileocolonic resection in a placebo-controlled double-blind clinical trial...
Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel diseaseGeert D'Haens
Department of Gastroenterology, Academic Medical Centre, Amsterdam, The Netherlands Imelda GI Clinical Research Centre, Bonheiden, Belgium
Inflamm Bowel Dis 18:2218-24. 2012..Fecal calprotectin is a marker of inflammation in inflammatory bowel disease (IBD). Since mucosal healing has become a goal of treatment in IBD we examined how reliably calprotectin levels reflect mucosal disease activity...
Immunogenicity of infliximab: how to handle the problem?Filip Baert
Department of Gastroenterology, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium
Acta Gastroenterol Belg 70:163-70. 2007..Antibody formation is associated with allergic reactions and loss of response...
Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's diseaseFilip Baert
Department of Internal Medicine, Division of Gastroenterology, University Hospital Gasthuisberg, Leuven, Belgium
N Engl J Med 348:601-8. 2003..Concomitant immunosuppressive therapy reduces the magnitude of the immunogenic response...
