Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in ratsSanser Gul
Department of Neurosurgery, School of Medicine, Zonguldak Karaelmas University, Esenkoy, Kozlu, Zonguldak 67600, Turkey
J Clin Neurosci 17:608-11. 2010
..0001). Mean luminal diameter of the basilar artery was significantly smaller in G3 than in G2 (p=0.02), G4 (p<0.018) and G5 (p<0.001). Our results confirm that ebselen may have neuroprotective effects by acting to prevent vasospasm...
Intraobserver and interobserver variability of Fuhrman and modified Fuhrman grading systems for conventional renal cell carcinomaSibel Bektas
Department of Pathology, School of Medicine, Zonguldak Karaelmas University, Kozlu, Zonguldak, Turkey
Kaohsiung J Med Sci 25:596-600. 2009
..Collapsing the Fuhrman grading into a two-tiered scheme improved the intraobserver and interobserver reproducibility...
CD24 and galectin-1 expressions in gastric adenocarcinoma and clinicopathologic significanceSibel Bektas
Department of Pathology, School of Medicine, Zonguldak Karaelmas University, 67600 Kozlu, Zonguldak, Turkey
Pathol Oncol Res 16:569-77. 2010
..Our findings suggest that these markers are independent prognostic indicators of poor survival and may serve as useful targets for novel therapies...
Effect of vardenafil on cerebral vasospasm following experimental subarachnoid hemorrhage in ratsSanser Gul
Department of Neurosurgery, School of Medicine, Zonguldak Karaelmas University, Kozlu, Zonguldak 67600, Turkey
J Clin Neurosci 17:1038-41. 2010
..008, G4 v. G2; p = 0.001, G4 v. G3; p = 0.005, G5 v. G2; p = 0.001, G5 v. G3). Our results confirm that vardenafil may induce vasodilatation and provide potential benefits in SAH therapy by preventing vasospasm...
Coenzyme Q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injuryBulent Erol
Department of Urology, Zonguldak Karaelmas University Faculty of Medicine, Zonguldak, Turkey
Fertil Steril 93:280-2. 2010
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Clinicopathological significance of fascin and CD44v6 expression in endometrioid carcinomaBanu Dogan Gun
Department of Pathology, Faculty of Medicine, Bulent Ecevit University, 67100 Kozlu, Zonguldak, Turkey
Diagn Pathol 7:80. 2012
..We aimed to investigate the expressions of both fascin and CD44v6 in endometrioid carcinomas and to evaluate their inter-relation with clinicopathological parameters...
The effects of dexmedetomidine dosage on cerebral vasospasm in a rat subarachnoid haemorrhage modelHilal Ayoglu
Department of Anesthesiology and Reanimation, School of Medicine, Zonguldak Karaelmas University, Kozlu, Zonguldak 67600, Turkey
J Clin Neurosci 17:770-3. 2010
..The MLD was lowest in Group H. PCNA expression was observed only in Group D10. We concluded that dexmedetomidine reduces oxidative stress and vasospasm following SAH in a dose-dependent manner...
Malignant melanoma associated with congenital melanocytic nevus and diagnosed with intestinal metastases: Two case reportsNilufer Onak Kandemir
Departments of, Pathology, Zonguldak Karaelmas University, School of Medicine, Zonguldak
Turk J Gastroenterol 22:77-82. 2011
..Malignant melanoma development in gastrointestinal system may have a primary or metastatic character. Definitive diagnosis always requires detailed clinical, histopathological and immunohistochemical analyses...
Effects of a new hemostatic agent Ankaferd Blood Stopper(®)on the intraocular tissues in rat modelAtilla Alpay
Department of Ophthalmology, Zonguldak Karaelmas University, Göz Hastaliklari Anabilim Dali, Kozlu 67600, Zonguldak, Turkey
Cutan Ocul Toxicol 31:128-31. 2012
..To investigate the histopathological changes due to administration of Ankaferd Blood Stopper(®) (ABS) into intraocular tissues by an anterior chamber and intravitreal injections...
Mitigation of indomethacin-induced gastric mucosal lesions by a potent specific type V phosphodiesterase inhibitorKemal Karakaya
Department of General Surgery, Zonguldak Karaelmas University, Medical Faculty, 67600 Kozlu, Zonguldak, Turkey
World J Gastroenterol 15:5091-6. 2009
..To investigate the gastroprotective effect of vardenafil against indomethacin-induced gastric damage...
Gliosarcoma with chondroblastic osteosarcomatous differentation: report of two case with clinicopathologic and immunohistochemical featuresFigen Barut
Zonguldak Karaelmas University Faculty of Medicine, Department of Pathology, Zonguldak, Turkey
Turk Neurosurg 19:417-22. 2009
..We report two cases with an extremely rare histopathological diagnosis of "gliosarcoma with features of chondroblastic osteosarcoma"...
Postoperative adhesions after application of topical hemostatic agents: outcomes in a rat partial nephrectomy modelHusnu Tokgoz
Department of Urology, Karaelmas University School of Medicine, Zonguldak, Turkey
Urology 78:970.e9-14. 2011
..To compare 3 kinds of topical hemostatic agents in terms of adhesive strength, control of hemorrhage, and postoperative intra-abdominal adhesions in an experimental partial nephrectomy (PN) model...
Comparison of the effects of bupivacaine, lidocaine, and tramadol infiltration on wound healing in ratsVolkan Hanci
Dokuz Eylul University, School of Medicine, Department of Anesthesiology and Reanimation Formerly Bulent Ecevit University, School of Medicine, Department of Anesthesiology and Reanimation, Izmir, Turkey
Rev Bras Anestesiol 62:799-810. 2012
..The aim of this study was to investigate the effects of saline solution, bupivacaine, lidocaine and tramadol infiltration on wound healing in rats...
Use of a novel haemostatic agent: ankaferd blood stopper in conjunctival incisionsAtilla Alpay
Department of Ophthalmology, The School of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
Clin Experiment Ophthalmol 39:793-8. 2011
..To investigate the haemostatic efficacy and histopathological effects of a new haemostatic agent, ankaferd blood stopper, in a rat conjunctival incision model...
Effect of dexmedetomidine on testicular torsion/detorsion damage in ratsVolkan Hanci
Department of Anesthesiology and Reanimation, Karaelmas University Medical Faculty, Zonguldak, Turkey
Urol Int 84:105-11. 2010
..We assessed the antioxidant activity of dexmedetomidine (DEX) during an ischemic period in a rat model of testicular torsion/detorsion (T/DT) by using biochemical and histopathological methods...
Universal markers of thyroid malignancies: galectin-3, HBME-1, and cytokeratin-19Figen Barut
Department of Pathology, Zonguldak Karaelmas University Faculty of Medicine, 67600, Kozlu, Zonguldak, Turkey
Endocr Pathol 21:80-9. 2010
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Vardenafil reduces testicular damage following ischemia/reperfusion injury in ratsBulent Erol
Department of Urology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
Kaohsiung J Med Sci 25:374-80. 2009
..Administration of 1 mg/kg vardenafil during testicular torsion decreased ischemia/reperfusion cellular damage. Our results indicate that the reduction in oxidative stress by vardenafil may play a major role in its cytoprotective effects...
Ectopic pancreas associated with choledochal cyst and multiseptate gallbladderBurak Bahadir
Department of Pathology, Zonguldak Karaelmas University, Kozlu, Zonguldak, Turkey
Pediatr Dev Pathol 9:312-5. 2006
..To our knowledge, this case represents the 1st one associated with these 3 entities and only the 2nd choledochal cyst with ectopic pancreatic tissue in its wall...
Effect of ghrelin on inflammatory response in lung contusionBerrak Guven
Department of Biochemistry, Faculty of Medicine, Bulent Ecevit University Formerly Karaelmas University, Zonguldak, Turkey
Kaohsiung J Med Sci 29:69-74. 2013
..In conclusion, our study demonstrates that acute lung injury initiated proinflammatory responses and ghrelin administration showed an anti-inflammatory effect in lung contusion...
Can lymphatic vascular density be used in determining metastatic spreading potential of tumor in invasive ductal carcinomas?Nilufer Onak Kandemir
Department of Pathology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
Pathol Oncol Res 18:253-62. 2012
..Peritumoral LVD in primary tumor tissue is closely related to parameters influencing the prognosis of a tumor...
Effects of ozone oxidative preconditioning on radiation-induced organ damage in ratsFatma Ayca Gultekin
Bulent Ecevit University, School of Medicine, Department of General Surgery, Kozlu, Zonguldak 67600, Turkey
J Radiat Res 54:36-44. 2013
..In conclusion, data obtained from this study indicated that ozone could increase the endogenous antioxidant defense mechanism in rats and there by protect the animals from radiation-induced organ toxicity...
Classic Kaposi sarcoma with sarcoid-like granulomas: a case report and literature reviewNilufer Onak Kandemir
Department of Pathology, School of Medicine, Zonguldak Karaelmas University, 67600, Kozlu, Zonguldak, Turkey
Exp Mol Pathol 87:89-93. 2009
..The association of soft tissue sarcomas with a granulomatous reaction is very rare. A granulomatous reaction is reported to be a good prognostic indicator in several carcinoma types, although its importance in sarcomas is unclear...
Nuclear morphometric analysis in gastrointestinal stromal tumors: a preliminary studySukru Oguz Ozdamar
Department of Pathology, Zonguldak Karaelmas University, Faculty of Medicine, Zonguldak
Turk J Gastroenterol 18:71-6. 2007
..In this study, the histomorphologic and immunohistochemical features of gastrointestinal stromal tumors are compared with nuclear morphometric results...
Effects of the folk medicinal plant extract Ankaferd Blood Stopper® on the ocular surfaceAtilla Alpay
Department of Ophthalmology, The School of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
Cutan Ocul Toxicol 30:280-5. 2011
..To investigate the effects of Ankaferd Blood Stopper(®) (ABS) on the ocular surface...
The effectiveness of dexmedetomidine in experimental spinal cord injury compared to methylprednisolone in ratsSanser Gul
Department of Neurosurgery, School of Medicine, Zonguldak Karaelmas University, Kozlu, Zonguldak 67600, Turkey
J Clin Neurosci 17:490-4. 2010
..0001; p=0.007). G4 had higher cell counts compared to G2 and G3 (p=0.0001; p=0.05). These findings indicated that dexmedetomidine might have neuroprotective effects in spinal cord injury...
Inflammatory myofibroblastic tumor of the perirenal soft tissue misdiagnosed as renal cell carcinomaSibel Bektas
Department of Pathology, Hacettepe University Hospital, Ankara, Turkey
Pathol Res Pract 203:461-5. 2007
..Our patient is recurrence-free in the 18th month of post-operative follow-up...