Orlando Graziani Povoas Barsottini

Summary

Publications

  1. ncbi request reprint Clinical and molecular neuroimaging characteristics of Brazilian patients with Parkinson's disease and mutations in PARK2 or PARK8 genes
    Orlando G P Barsottini
    Instituto Israelita de Ensino e Pesquisa, Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 67:7-11. 2009
  2. ncbi request reprint Differentiation of Parkinson's disease and progressive supranuclear palsy with magnetic resonance imaging: the first Brazilian experience
    Orlando G P Barsottini
    Department of Neurology, Universidade Federal de Sao Paulo, Rua Cabedelo, 265 São Paulo, SP, Brazil
    Parkinsonism Relat Disord 13:389-93. 2007
  3. ncbi request reprint Progressive supranuclear palsy: new concepts
    Orlando Graziani Povoas Barsottini
    Department of Neurology and Neurosurgery, Federal University of Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 68:938-46. 2010
  4. doi request reprint Cognitive impairment in Brazilian patients with Behçet's disease occurs independently of neurologic manifestation
    Livia Almeida Dutra
    Department of Neurology and Neurosurgery, Division of General Neurology, Universidade Federal de Sao Paulo, Brazil
    J Neurol Sci 327:1-5. 2013
  5. doi request reprint Cognitive and olfactory deficits in Machado-Joseph disease: a dopamine transporter study
    Pedro Braga-Neto
    Ataxia Unit, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Parkinsonism Relat Disord 18:854-8. 2012
  6. doi request reprint Cognitive deficits in Machado-Joseph disease correlate with hypoperfusion of visual system areas
    Pedro Braga-Neto
    Ataxia Unit, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Cerebellum 11:1037-44. 2012
  7. doi request reprint Sleep disorders in Machado-Joseph disease: a dopamine transporter imaging study
    Jose Luiz Pedroso
    Department of Neurology, Ataxia Unit, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    J Neurol Sci 324:90-3. 2013
  8. doi request reprint Substantia nigra echogenicity is correlated with nigrostriatal impairment in Machado-Joseph disease
    Jose Luiz Pedroso
    Department of Neurology, Ataxia Unit, Universidade Federal de Sao Paulo, Rua Botucatu, 740, São Paulo 04 023 900, SP, Brazil
    Parkinsonism Relat Disord 19:742-5. 2013
  9. doi request reprint Atypical manifestations in Brazilian patients with neuro-Behçet's disease
    Livia Almeida Dutra
    General Neurology Division, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, R Pedro de Toledo, 650 Vila Clementino, São Paulo 04039 002, Brazil
    J Neurol 259:1159-65. 2012
  10. doi request reprint Cerebellar cognitive affective syndrome in Machado Joseph disease: core clinical features
    Pedro Braga-Neto
    Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, 650 Pedro de Toledo St, Vila Clementino, Sao Paulo, SP, Brazil
    Cerebellum 11:549-56. 2012

Collaborators

  • Jose Luiz Pedroso
  • Pedro Braga-Neto
  • Livia Almeida Dutra
  • Rodrigo A Bressan
  • Clecio Godeiro
  • Edson Bor-Seng-Shu
  • Marcelo Queiroz Hoexter
  • Andre C Felicio
  • Clecio Godeiro-Junior
  • Vanderci Borges
  • Sonia M A Silva
  • Carolina Candeias da Silva
  • Carolina Yuri P Aizawa
  • Henrique B Ferraz
  • Francisco Araujo
  • Fabiano Mesquita Callegari
  • Marilia Rezende Callegari
  • João Norberto Stavale
  • René Leandro M Rivero
  • Fabio Fieni Toso
  • Fabiano Moulin de Moraes
  • Ming C Shih
  • Patricia de Carvalho Aguiar
  • Luiz A F Andrade
  • Luiz Augusto F Andrade
  • Henrique Ballalai Ferraz
  • Patricia M de Carvalho-Aguiar
  • Aline P M Pinto
  • Juliana M F Sallum
  • Helio G Teive
  • Patricia M de Carvalho Aguiar
  • Lucianna G Alberto

Detail Information

Publications29

  1. ncbi request reprint Clinical and molecular neuroimaging characteristics of Brazilian patients with Parkinson's disease and mutations in PARK2 or PARK8 genes
    Orlando G P Barsottini
    Instituto Israelita de Ensino e Pesquisa, Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 67:7-11. 2009
    ..To describe clinical and neuroimaging (SPECT) characteristics of Brazilian patients with Parkinson's disease (PD) and mutations in PARK2 or PARK8 genes...
  2. ncbi request reprint Differentiation of Parkinson's disease and progressive supranuclear palsy with magnetic resonance imaging: the first Brazilian experience
    Orlando G P Barsottini
    Department of Neurology, Universidade Federal de Sao Paulo, Rua Cabedelo, 265 São Paulo, SP, Brazil
    Parkinsonism Relat Disord 13:389-93. 2007
    ..The objective of this study is to differentiate PSP from Parkinson's disease through magnetic resonance imaging...
  3. ncbi request reprint Progressive supranuclear palsy: new concepts
    Orlando Graziani Povoas Barsottini
    Department of Neurology and Neurosurgery, Federal University of Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 68:938-46. 2010
    ....
  4. doi request reprint Cognitive impairment in Brazilian patients with Behçet's disease occurs independently of neurologic manifestation
    Livia Almeida Dutra
    Department of Neurology and Neurosurgery, Division of General Neurology, Universidade Federal de Sao Paulo, Brazil
    J Neurol Sci 327:1-5. 2013
    ..Nonetheless, there are reports of cognitive impairment in patients without neurological manifestations...
  5. doi request reprint Cognitive and olfactory deficits in Machado-Joseph disease: a dopamine transporter study
    Pedro Braga-Neto
    Ataxia Unit, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Parkinsonism Relat Disord 18:854-8. 2012
    ..This finding raises the possibility of extra-striatal dopamine and other neurotransmitter system involvement or of cerebellum neurodegeneration exerting a direct influence on cognitive and sensorial information processing in MJD...
  6. doi request reprint Cognitive deficits in Machado-Joseph disease correlate with hypoperfusion of visual system areas
    Pedro Braga-Neto
    Ataxia Unit, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Cerebellum 11:1037-44. 2012
    ..The visuospatial system is affected in patients with SCA3/MJD and may be responsible for the cognitive deficits seen in this disease...
  7. doi request reprint Sleep disorders in Machado-Joseph disease: a dopamine transporter imaging study
    Jose Luiz Pedroso
    Department of Neurology, Ataxia Unit, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    J Neurol Sci 324:90-3. 2013
    ..This study assessed the relationship between sleep disorders in MJD and dopamine transporter (DAT) densities...
  8. doi request reprint Substantia nigra echogenicity is correlated with nigrostriatal impairment in Machado-Joseph disease
    Jose Luiz Pedroso
    Department of Neurology, Ataxia Unit, Universidade Federal de Sao Paulo, Rua Botucatu, 740, São Paulo 04 023 900, SP, Brazil
    Parkinsonism Relat Disord 19:742-5. 2013
    ..The present study aimed to correlate the SN echogenic size and striatal dopamine transporter density in MJD patients...
  9. doi request reprint Atypical manifestations in Brazilian patients with neuro-Behçet's disease
    Livia Almeida Dutra
    General Neurology Division, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, R Pedro de Toledo, 650 Vila Clementino, São Paulo 04039 002, Brazil
    J Neurol 259:1159-65. 2012
    ..Brazilian NBD patients present more parenchymal and atypical manifestations, and relapse more often than NBD patients from other populations...
  10. doi request reprint Cerebellar cognitive affective syndrome in Machado Joseph disease: core clinical features
    Pedro Braga-Neto
    Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, 650 Pedro de Toledo St, Vila Clementino, Sao Paulo, SP, Brazil
    Cerebellum 11:549-56. 2012
    ..We speculate on a possible role in visual cortical processing degeneration and executive dysfunction in our patients as a model to explain their main cognitive deficit...
  11. doi request reprint Clinical spectrum of early onset cerebellar ataxia with retained tendon reflexes: an autosomal recessive ataxia not to be missed
    Jose Luiz Pedroso
    Department of Neurology, Ataxia Unit, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo SP, Brazil
    Arq Neuropsiquiatr 71:345-8. 2013
    ..Further molecular studies are required to provide definitive answers to the questions that remain regarding early onset cerebellar ataxia with retained tendon reflexes. ..
  12. ncbi request reprint Neurosarcoidosis: guidance for the general neurologist
    Livia Almeida Dutra
    Division of General Neurology, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Brazil
    Arq Neuropsiquiatr 70:293-9. 2012
    ..We revised pathophysiology, clinical manifestations, diagnostic work up, and treatment of NS as guidance for the general neurologist...
  13. doi request reprint Is neuropathy involved with restless legs syndrome in Machado-Joseph disease?
    Jose Luiz Pedroso
    Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Eur Neurol 66:200-3. 2011
    ..To evaluate a group of spinocerebellar ataxia type 3 (SCA3) or Machado-Joseph disease (MJD) (SCA3/MJD) patients and assess whether there is an association between neuropathy and serum ferritin levels and restless legs syndrome (RLS)...
  14. doi request reprint Sleep disorders in machado-joseph disease: frequency, discriminative thresholds, predictive values, and correlation with ataxia-related motor and non-motor features
    Jose Luiz Pedroso
    Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Rua Botucatu, 740, 04 023 900, Sao Paulo, Sao Paulo, Brazil
    Cerebellum 10:291-5. 2011
    ..86). Within-SCA3/MJD group analysis showed that anxiety and depression were significantly correlated with RDB, but not with RLS. Additionally, depression was considered the best predictive clinical feature for RDB and EDS...
  15. ncbi request reprint Familial Behr syndrome-like phenotype with autosomal dominant inheritance
    Andre C Felicio
    Department of Neurology and Neurosurgery, Federal University of Sao Paulo, Sao Paulo, Brazil
    Parkinsonism Relat Disord 14:370-2. 2008
    ..Autosomal dominant inheritance has also been described. In this case report we present a family pedigree of patients with an inherited autosomal dominant Behr syndrome-like phenotype emphasizing their clinical and neuroimaging features...
  16. doi request reprint Evaluation of patients with Clinically Unclear Parkinsonian Syndromes submitted to brain SPECT imaging using the technetium-99m labeled tracer TRODAT-1
    Andre C Felicio
    Department of Neurology and Neurosurgery, Movement Disorder Unit, Federal University of Sao Paulo, Sao Paulo, Brazil
    J Neurol Sci 291:64-8. 2010
    ..In conclusion, our data provided further information about the role of the technetium-99m labeled tracer TRODAT-1 as a biomarker of DAT reduction that can also be used in the diagnosis of patients with CUPS...
  17. doi request reprint PINK1 mutations in a Brazilian cohort of early-onset Parkinson's disease patients
    Clecio Godeiro-Junior
    Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, SP, Brazil
    Mov Disord 24:1693-6. 2009
    ..The results of our study support the hypothesis that mutations in PINK1 may not be a relevant cause of EOPD. In Brazil, if we consider only EOPD patients, it seems that parkin and LRRK2 mutations are more common...
  18. ncbi request reprint Sneddon's syndrome: case report and review of its relationship with antiphospholipid syndrome
    Livia Almeida Dutra
    Departament of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil
    Einstein (Sao Paulo) 10:230-2. 2012
    ..It is important to recognize the Sneddon's syndrome, particularly because stroke episodes may be prevented through appropriate treatment...
  19. doi request reprint Epilepsy and Behçet's disease: cortical and hippocampal involvement in Brazilian patients
    Livia Almeida Dutra
    Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo UNIFESP, Escola Paulista de Medicina, Brazil
    J Neurol Sci 309:1-4. 2011
    ..To describe clinical, radiological and electrophysiological findings in epileptic neuro-Behçet's (NBD) patients...
  20. ncbi request reprint Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family
    Jose Luiz Pedroso
    Department of Neurology and Neurosurgery, Division of General Neurology and Ataxias, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 69:288-91. 2011
    ..Several ARSACS cases have been reported outside Canada in recent decades. This is the first report of typical clinical and neuroimaging features in a Brazilian family with probable diagnosis of ARSACS...
  21. ncbi request reprint Transcranial sonography in Parkinson's disease
    Edson Bor-Seng-Shu
    Division of Clinical Neurosurgery, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    Einstein (Sao Paulo) 10:242-6. 2012
    ..This study discussed how the hyperechogenicity of the substantia nigra may facilitate the differential diagnosis of parkinsonian syndromes...
  22. doi request reprint Patients with autosomal dominant spinocerebellar ataxia have more risk of falls, important balance impairment, and decreased ability to function
    Carolina Yuri P Aizawa
    Universidade Federal de Sao Paulo, Department of Neurology, Sao Paulo, Brazil
    Arq Neuropsiquiatr 71:508-11. 2013
    ..To assess balance and ability to function in patients with spinocerebellar ataxia...
  23. ncbi request reprint Machado-Joseph disease in Brazil: from the first descriptions to the emergence as the most common spinocerebellar ataxia
    Jose Luiz Pedroso
    Department of Neurology, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 70:630-2. 2012
    ..Brazilian researchers have distinguished themselves in the ongoing investigation seeking new knowledge about Machado-Joseph disease...
  24. ncbi request reprint Neurological contributions from William Osler
    Jose Luiz Pedroso
    Department of Neurology, Division of General Neurology and Ataxias, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo SP, Brazil
    Arq Neuropsiquiatr 71:258-60. 2013
    ..He performed more than 800 autopsies studies of the nervous system and published over 200 articles in the field of Neurology. In this article, we described the main neurological contributions from William Osler...
  25. doi request reprint Teaching NeuroImages: Rosai-Dorfman disease presenting with progressive early-onset cerebellar ataxia
    Carolina Candeias da Silva
    From the Department of Neurology, Ataxia Unit C C d S, J L P, F M d M, F F T, O G P B, and Department of Pathology F M C, F A, J N S, Universidade Federal de São Paulo and Department of Radiology R L M R, Universidade Federal de São Paulo and Delboni Auriemo, Diagnósticos da América, Sao Paulo, Brazil
    Neurology 81:e27-8. 2013
    ..Histopathology of the cervical lymph node confirmed Rosai-Dorfman disease (RDD) by showing emperipolesis (figure, C and D). The patient will be followed up in order to determine disease progression and therapy. ..
  26. ncbi request reprint Translation and validation into Brazilian version of the Scale of the Assessment and Rating of Ataxia (SARA)
    Pedro Braga-Neto
    Department of Neurology and Neurosurgery, Escola Paulista de Medicina, Federal University of Sao Paulo, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 68:228-30. 2010
    ..The objective of this study was to translate and validate SARA into Brazilian Portuguese...
  27. pmc Gradenigo's Syndrome: Beyond the Classical Triad of Diplopia, Facial Pain and Otorrhea
    Jose Luiz Pedroso
    Departments of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Case Rep Neurol 3:45-7. 2011
    ..Careful clinical history and physical examination, including neuroimaging, are necessary to make a differential diagnosis...
  28. doi request reprint PINK1 polymorphism IVS1-7 A-->G, exposure to environmental risk factors and anticipation of disease onset in Brazilian patients with early-onset Parkinson's Disease
    Clecio Godeiro
    Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Sao Paulo SP, Brazil
    Neurosci Lett 469:155-8. 2010
    ....
  29. ncbi request reprint Clinical features of dystonia in atypical parkinsonism
    Clecio Godeiro-Junior
    Movement Disorders Unit, Department of Neurology and Neurosurgery, Federal University of Sao Paulo, Sao Paulo SP, Brazil
    Arq Neuropsiquiatr 66:800-4. 2008
    ..The association between Dystonia and Parkinson's disease (PD) has been well described especially for foot and hand dystonia. There is however few data on dystonic postures in patients with atypical parkinsonism...