X Baraliakos

Summary

Publications

  1. doi request reprint Opinion: Perspectives on imaging in axial spondyloarthritis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Landgrafenstrasse 15, 44652 Herne, Germany
    Nat Rev Rheumatol 9:498-502. 2013
  2. doi request reprint Imaging in axial spondyloarthritis: diagnostic problems and pitfalls
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Rheum Dis Clin North Am 38:513-22. 2012
  3. doi request reprint Update of the literature review on treatment with biologics as a basis for the first update of the ASAS/EULAR management recommendations of ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Landgrafenstr 15, 44652 Herne, Germany
    Rheumatology (Oxford) 51:1378-87. 2012
  4. doi request reprint Spondyloarthritides
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Herne, Germany
    Best Pract Res Clin Rheumatol 25:825-42. 2011
  5. doi request reprint [MRI examinations for axial and peripheral spondyloarthritis]
    X Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr Universitat Bochum, Landgrafenstr 15, 44652, Herne, Deutschland
    Z Rheumatol 71:27-37. 2012
  6. pmc Inflammation in ankylosing spondylitis: a systematic description of the extent and frequency of acute spinal changes using magnetic resonance imaging
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652 Herne, Germany
    Ann Rheum Dis 64:730-4. 2005
  7. ncbi request reprint Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-alpha antibody infliximab
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Ruhr University Bochum, Germany
    Rheumatology (Oxford) 46:1450-3. 2007
  8. ncbi request reprint Differences in the incidence of flares or new onset of inflammatory bowel diseases in patients with ankylosing spondylitis exposed to therapy with anti-tumor necrosis factor alpha agents
    J Braun
    Ruhr University Bochum, Germany
    Arthritis Rheum 57:639-47. 2007
  9. pmc Assessment of acute spinal inflammation in patients with ankylosing spondylitis by magnetic resonance imaging: a comparison between contrast enhanced T1 and short tau inversion recovery (STIR) sequences
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Ruhr University Bochum, Germany
    Ann Rheum Dis 64:1141-4. 2005
  10. doi request reprint Development of a radiographic scoring tool for ankylosing spondylitis only based on bone formation: addition of the thoracic spine improves sensitivity to change
    X Baraliakos
    Rheumazentrum Ruhrgebiet and Ruhr University Bochum, Herne, Germany
    Arthritis Rheum 61:764-71. 2009

Detail Information

Publications32

  1. doi request reprint Opinion: Perspectives on imaging in axial spondyloarthritis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Landgrafenstrasse 15, 44652 Herne, Germany
    Nat Rev Rheumatol 9:498-502. 2013
    ..This Perspectives article provides an overview of the role of imaging in the diagnosis and management of axSpA, and also discusses open questions and future perspectives in this field. ..
  2. doi request reprint Imaging in axial spondyloarthritis: diagnostic problems and pitfalls
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Rheum Dis Clin North Am 38:513-22. 2012
    ..Diagnosis of SpA should result from the combination of clinical, laboratory and imaging findings...
  3. doi request reprint Update of the literature review on treatment with biologics as a basis for the first update of the ASAS/EULAR management recommendations of ankylosing spondylitis
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Landgrafenstr 15, 44652 Herne, Germany
    Rheumatology (Oxford) 51:1378-87. 2012
    ..To perform a literature review as basis for the update of the Assessment in SpondyloArthritis international Society/European League Against Rheumatism (ASAS/EULAR) treatment recommendations with biologics in AS...
  4. doi request reprint Spondyloarthritides
    Xenofon Baraliakos
    Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Herne, Germany
    Best Pract Res Clin Rheumatol 25:825-42. 2011
    ..As far as it stands now, TNF blockers seem to have no influence on new bone formation in AS...
  5. doi request reprint [MRI examinations for axial and peripheral spondyloarthritis]
    X Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr Universitat Bochum, Landgrafenstr 15, 44652, Herne, Deutschland
    Z Rheumatol 71:27-37. 2012
    ..However, conventional radiographs are still the gold standard for the assessment of structural changes in SpA. A combination of both imaging techniques is recommended in clinical practice...
  6. pmc Inflammation in ankylosing spondylitis: a systematic description of the extent and frequency of acute spinal changes using magnetic resonance imaging
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652 Herne, Germany
    Ann Rheum Dis 64:730-4. 2005
    ..Magnetic resonance imaging (MRI) is increasingly used to detect inflammation in the spine of patients with ankylosing spondylitis (AS)...
  7. ncbi request reprint Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-alpha antibody infliximab
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Ruhr University Bochum, Germany
    Rheumatology (Oxford) 46:1450-3. 2007
    ..The objective of this article was to study the effect of infliximab on structural changes in AS over 4 yrs...
  8. ncbi request reprint Differences in the incidence of flares or new onset of inflammatory bowel diseases in patients with ankylosing spondylitis exposed to therapy with anti-tumor necrosis factor alpha agents
    J Braun
    Ruhr University Bochum, Germany
    Arthritis Rheum 57:639-47. 2007
    ..The purpose our study was to analyze the incidence of flares and new onset of IBD in patients with AS treated with anti-TNF agents...
  9. pmc Assessment of acute spinal inflammation in patients with ankylosing spondylitis by magnetic resonance imaging: a comparison between contrast enhanced T1 and short tau inversion recovery (STIR) sequences
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Ruhr University Bochum, Germany
    Ann Rheum Dis 64:1141-4. 2005
    ....
  10. doi request reprint Development of a radiographic scoring tool for ankylosing spondylitis only based on bone formation: addition of the thoracic spine improves sensitivity to change
    X Baraliakos
    Rheumazentrum Ruhrgebiet and Ruhr University Bochum, Herne, Germany
    Arthritis Rheum 61:764-71. 2009
    ..Our objective was to study the contribution of the lower part of the T-spine to structural damage in patients with ankylosing spondylitis (AS)...
  11. ncbi request reprint Persistent clinical efficacy and safety of anti-tumour necrosis factor alpha therapy with infliximab in patients with ankylosing spondylitis over 5 years: evidence for different types of response
    J Braun
    Rheumatology Medical Center Ruhrgebiet, Herne, Germany
    Ann Rheum Dis 67:340-5. 2008
    ..There is insufficient evidence for the long-term efficacy and safety of anti-tumour necrosis factor therapy in patients with ankylosing spondylitis (AS). This is the first report on the treatment with infliximab over 5 years...
  12. ncbi request reprint Outcome of patients with active ankylosing spondylitis after two years of therapy with etanercept: clinical and magnetic resonance imaging data
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Ruhr University Bochum, Bochum, Germany
    Arthritis Rheum 53:856-63. 2005
    ....
  13. pmc Radiographic progression in patients with ankylosing spondylitis after 2 years of treatment with the tumour necrosis factor alpha antibody infliximab
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Ruhr University Bochum, Germany
    Ann Rheum Dis 64:1462-6. 2005
    ..It is unclear whether anti-TNF treatment affects chronic spinal changes in AS...
  14. pmc Efficacy of sulfasalazine in patients with inflammatory back pain due to undifferentiated spondyloarthritis and early ankylosing spondylitis: a multicentre randomised controlled trial
    J Braun
    Rheumazentrum Ruhrgebiet, Landgrafenstrasse 15, 44652 Herne, Germany
    Ann Rheum Dis 65:1147-53. 2006
    ..To assess the effect of sulfasalazine (SSZ) on inflammatory back pain (IBP) due to active undifferentiated spondyloarthritis (uSpA) or ankylosing spondylitis in patients with symptom duration <5 years...
  15. pmc Analysing chronic spinal changes in ankylosing spondylitis: a systematic comparison of conventional x rays with magnetic resonance imaging using established and new scoring systems
    J Braun
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Ann Rheum Dis 63:1046-55. 2004
    ..To compare conventional radiography and magnetic resonance imaging (MRI) for detection of chronic changes in the spine of patients with ankylosing spondylitis (AS)...
  16. pmc Progression of radiographic damage in patients with ankylosing spondylitis: defining the central role of syndesmophytes
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652 Herne, Germany
    Ann Rheum Dis 66:910-5. 2007
    ..These can be quantified by the modified Stokes Anklylosing Spondylitis Spinal Score (mSASSS). It is unknown which radiographic feature is most relevant for the assessment of change and the prediction of future damage in AS...
  17. ncbi request reprint Decreased incidence of anterior uveitis in patients with ankylosing spondylitis treated with the anti-tumor necrosis factor agents infliximab and etanercept
    J Braun
    Rheumazentrum Ruhrgebiet, and Ruhr University Bochum, Herne, Germany
    Arthritis Rheum 52:2447-51. 2005
    ..To estimate the incidence of anterior uveitis in patients with ankylosing spondylitis (AS) who underwent anti-tumor necrosis factor (anti-TNF) therapy, using data from recently performed trials...
  18. ncbi request reprint Magnetic resonance imaging examinations of the spine in patients with ankylosing spondylitis before and after therapy with the tumor necrosis factor alpha receptor fusion protein etanercept
    X Baraliakos
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Arthritis Rheum 52:1216-23. 2005
    ..To assess spinal inflammation by magnetic resonance imaging (MRI) before and after treatment with the tumor necrosis factor receptor fusion protein etanercept compared with placebo...
  19. ncbi request reprint Persistent clinical response to the anti-TNF-alpha antibody infliximab in patients with ankylosing spondylitis over 3 years
    J Braun
    Rheumatology Medical Center, Ruhrgebeit, Herne, Ruhr University, Bochum, Germany
    Rheumatology (Oxford) 44:670-6. 2005
    ..This report provides analyses from a 3-yr extension study, as a follow-up to both the 1- and 2-yr open label extensions of the original 3-month randomized controlled trial of infliximab in patients with AS...
  20. doi request reprint The degree of spinal inflammation is similar in patients with axial spondyloarthritis who report high or low levels of disease activity: a cohort study
    U Kiltz
    Department of Rheumatology, Rheumazentrum Ruhrgebiet, St Josefs Krankenhaus, Landgrafenstr, 15 44652 Herne, Germany
    Ann Rheum Dis 71:1207-11. 2012
    ..How this relates to spinal inflammation is unknown...
  21. ncbi request reprint Therapy of ankylosing spondylitis. Part II: biological therapies in the spondyloarthritides
    J Braun
    Rheumazentrum Ruhrgebiet, Herne and University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    Scand J Rheumatol 34:178-90. 2005
    ..However, severe infections, including tuberculosis, have been reported. These can be largely prevented by appropriate screening. The benefits of anti-TNF therapy in AS seem to outweigh these shortcomings...
  22. doi request reprint A comparison of new bone formation in patients with ankylosing spondylitis and patients with diffuse idiopathic skeletal hyperostosis: a retrospective cohort study over six years
    X Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Herne, Germany
    Arthritis Rheum 64:1127-33. 2012
    ..This study was undertaken to compare the natural course of new bone formation in AS and DISH...
  23. ncbi request reprint [Differential diagnosis of back pain in patients with ankylosing spondylitis: instable cervical spine fracture]
    M van Werde
    Rheumazentrum Ruhrgebiet, Herne, St Vincenz Gruppe Ruhr
    Dtsch Med Wochenschr 137:1740-2. 2012
    ..Physical examination revealed generally decreased mobility of an already hyperkyphotic cervical spine (CS) and decreased thoracic excursion. The paravertebral muscles were stiff ...
  24. ncbi request reprint [Spondyloarthritis - the novel concept. An introduction to the diagnosis and treatment of axial spondyloarthritis]
    U Kiltz
    Rheumazentrum Ruhrgebiet, Herne
    Dtsch Med Wochenschr 137:1745-7. 2012
    ..This subset is characterized by the absence of structural changes on conventional x-rays. In this review we describe the clinical symptoms, the diagnosis and therapy of patients with axial SpA...
  25. doi request reprint Imaging of axial spondyloarthritis including ankylosing spondylitis
    J Braun
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652 Herne, Germany
    Ann Rheum Dis 70:i97-103. 2011
    ..Low sclerostin and DKK-1 serum levels, both inhibitors of bone formation, were found to be associated with syndesmophyte formation in patients with AS...
  26. doi request reprint [What is ascertained in the therapy of axial spondyloarthritis?]
    J Braun
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652, Herne, Deutschland
    Internist (Berl) 54:1450-8. 2013
    ..NSAIDs need to be given continuously and biologics for longer periods of time. Patients with elevated C-reactive protein levels benefit most when treated consequently. ..
  27. ncbi request reprint Therapy of ankylosing spondylitis--a review. Part I: Conventional medical treatment and surgical therapy
    J Braun
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Scand J Rheumatol 34:97-108. 2005
    ..AS-specific problems are spinal fractures and atlantoaxial instability, which need careful management including surgery. Joint replacement therapy is established and beneficial for AS-disturbed joints of the hip and knee...
  28. ncbi request reprint High prevalence of anti-CD74 antibodies specific for the HLA class II-associated invariant chain peptide (CLIP) in patients with axial spondyloarthritis
    X Baraliakos
    Rheumazentrum Ruhrgebiet Herne, Herne, Germany
    Ann Rheum Dis 73:1079-82. 2014
    ..We examined the prevalence, sensitivity and specificity of anti-CLIP-ABs in axSpA in comparison with controls...
  29. ncbi request reprint Magnetic resonance imaging examinations of the spine in patients with ankylosing spondylitis, before and after successful therapy with infliximab: evaluation of a new scoring system
    J Braun
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Arthritis Rheum 48:1126-36. 2003
    ....
  30. ncbi request reprint Glucocorticoid treatment in spondyloarthritis
    C Fendler
    Rheumazentrum Ruhrgebiet, Herne, Germany
    Clin Exp Rheumatol 29:S139-42. 2011
    ..Future studies are needed to clarify this important issue for usual patient care...
  31. pmc 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis
    J Braun
    Rheumazentrum Ruhrgebiet, Landgrafenstrasse 15, 44652 Herne, Germany
    Ann Rheum Dis 70:896-904. 2011
    ..There are now 11 bullet points including 2 new ones, one related to extra-articular manifestations and one to changes in the disease course. With a mean score of 9.1 (range 8-10) the SOR was generally very good...
  32. doi request reprint [Perioperative use of biologicals in rheumatoid arthritis]
    F Heldmann
    Rheumazentrum Ruhrgebiet, Landgrafenstr 15, 44652, Herne
    Z Rheumatol 70:14-20. 2011
    ..Therefore, individualized management based on risk stratification for postoperative complications seems currently to be the best solution...