The role of inflammatory cytokines in Meigs' syndromeYoram Abramov
Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel
Obstet Gynecol 99:917-9. 2002
..CONCLUSION: The correlation between these inflammatory cytokines and the clinical course of Meigs' syndrome suggests their involvement in the formation of ascites and hydrothorax in this disorder...
Relevance of circulating biomarkers for the therapy monitoring and follow-up investigations in patients with non-small cell lung cancerVivian Barak
Sharett Institute of Oncology, Hadassah Medical Organization, Jerusalem, Israel
Cancer Biomark 6:191-6. 2010
..Further, we suggest a scenario to reveal the power of the defined biomarker use in future and to include those markers into the individual management of NSCLC patients...
PADMA-28, a Tibetan herbal preparation is an inhibitor of inflammatory cytokine productionVivian Barak
Immunology Laboratory for Tumor Diagnosis, Israeli Cytokine Standardization Laboratory, Faculty of Dental Medicine, Hebrew University Hadassah Medical Center, Jerusalem, Israel
Eur Cytokine Netw 15:203-9. 2004
..In humans, PADMA-28 attenuated the symptoms associated with intermittent claudications in atherosclerotic patients...
Interleukin-18 levels correlate with severe ovarian hyperstimulation syndromeVivian Barak
Obstetrics and Gynecology Department, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Fertil Steril 82:415-20. 2004
..To assess the involvement of interleukin-18 (IL-18) in the pathophysiology of severe ovarian hyperstimulation syndrome (OHSS), and study its use as a marker of disease and its correlation to capillary hyperpermeability...
The effect of herbal remedies on the production of human inflammatory and anti-inflammatory cytokinesVivian Barak
Immunology Laboratory for Tumor Diagnosis, Department of Oncology, Hadassah University Hospital, Jerusalem, Israel
Isr Med Assoc J 4:919-22. 2002
..Some herbal remedies are sold as food additives and are believed to have immune-enhancing properties...
The diagnostic and prognostic value of ProGRP in lung cancerBenjamin Nisman
Department of Oncology, Hadassah and Hebrew University Medical Centre, Jerusalem 91120, Israel
Anticancer Res 29:4827-32. 2009
..Aim: To investigate the diagnostic and prognostic significance of pro-gastrin-releasing peptide (ProGRP) in non-small cell (NSCLC) and small cell lung cancer (SCLC) and compare this marker with other known serum markers in lung cancer...
Trends in liver function tests: a comparison with serum tumor markers in metastatic uveal melanoma (part 2)Karen Hendler
Department of Ophthalmology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Anticancer Res 31:351-7. 2011
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The dynamics of serum tumor markers in predicting metastatic uveal melanoma (part 1)Vivian Barak
Immunology Laboratory for Tumor Diagnosis, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Anticancer Res 31:345-9. 2011
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The follow-up of patients with non-muscle-invasive bladder cancer by urine cytology, abdominal ultrasound and urine CYFRA 21-1: a pilot studyBenjamin Nisman
Department of Oncology, Hadassah and Hebrew University Medical Centre, P O Box 12000, Jerusalem 91120, Israel
Anticancer Res 29:4281-5. 2009
..This study aimed to evaluate the accuracy of urine cytology, bladder ultrasound (US), urine cytokeratin 19 fragment assay (CYFRA 21-1) and the combination of these noninvasive modalities in the detection of recurrent bladder cancer...
Using the direct-injection model of early uveal melanoma hepatic metastasis to identify TPS as a potentially useful serum biomarkerVivian Barak
Immunology Laboratory for Tumor Diagnosis, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Invest Ophthalmol Vis Sci 48:4399-402. 2007
..To develop a method to screen for serum biomarkers of early hepatic metastasis from uveal melanoma...
VEGF as a biomarker for metastatic uveal melanoma in humansVivian Barak
Immunology Laboratory for Tumor Diagnosis, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Curr Eye Res 36:386-90. 2011
..The aim of this study was to examine the potential of VEGF serum level as a tumor marker for metastases in uveal melanoma (UM) patients...
The prognostic significance of circulating neuroendocrine markers chromogranin a, pro-gastrin-releasing peptide and neuron-specific enolase in patients with advanced non-small-cell lung cancerBenjamin Nisman
Department of Oncology, Hadassah University Hospital, Jerusalem, Israel
Tumour Biol 27:8-16. 2006
..The aim of the present study was to assess the value of serum levels of these markers in predicting response to chemotherapy and survival of patients with unresectable NSCLC...
Characterizing the involvement of the nuclear factor-kappa B (NF kappa B) transcription factor in uveal melanomaRinat Dror
Department of Ophthalmology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Invest Ophthalmol Vis Sci 51:1811-6. 2010
..The role of NFkappaB as a therapeutic target for UM should be further evaluated...
Cytokines levels, severity of acute mucositis and the need of PEG tube installation during chemo-radiation for head and neck cancer--a prospective pilot studyAmichay Meirovitz
Department of Oncology, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Radiat Oncol 5:16. 2010
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Interplay among oxidants, antioxidants, and cytokines in skin disorders: present status and future considerationsMeital Portugal
Department of Pharmaceutics, School of Pharmacy, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Biomed Pharmacother 61:412-22. 2007
..Furthermore, it is expected that future studies should explore the possible roles of the synergistic interactions between antioxidants and cytokines and their impact on the Th1/Th2 cytokine networks balances...
Recombinant luteinizing hormone induces increased production of ovarian follicular adiponectin in vivo: implications for enhanced insulin sensitivityGuy Gutman
Sara Racine IVF Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Fertil Steril 91:1837-41. 2009
..To determine in vivo whether LH supplementation during the late follicular phase induces increased production of ovarian follicle adiponectin in humans...
Serum markers to detect metastatic uveal melanomaVivian Barak
Immunology Laboratory for Tumor Diagnosis, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Anticancer Res 27:1897-900. 2007
..S-100beta and melanoma-inhibitory activity (MIA) serum levels are elevated in metastatic cutaneous melanoma. The ability of OPN, S-100beta and MIA serum levels to be used as non-invasive markers for detecting metastatic UM was tested...
Clinical utility of cytokeratins as tumor markersVivian Barak
Immunology Laboratory for Tumor Diagnosis, Oncology Department, Hadassah University Hospital, Jerusalem, Israel
Clin Biochem 37:529-40. 2004
..Cytokeratin tumor markers can accurately predict disease status before conventional methods and offer a simple, noninvasive, cheap, and reliable tool for more efficient management...
Cytokine levels in gingival crevicular fluid of erupting primary teeth correlated with systemic disturbances accompanying teethingJoseph Shapira
Department of Pediatric Dentistry, Hebrew University, Hadassah Faculty of Dental Medicine, Jerusalem, Israel
Pediatr Dent 25:441-8. 2003
..This increase could explain such clinical manifestations as fever, diarrhea, increased crying, and sleeping and eating disturbances that occur at this time...
Markedly elevated levels of inflammatory cytokines in maternal serum and peritoneal washing during arrested laborYoram Abramov
Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center, Ein Kerem, Jerusalem, Israel
Acta Obstet Gynecol Scand 83:358-63. 2004
..We measured levels of inflammatory cytokines in maternal serum and peritoneal washings in arrested first stage of labor to assess the possible involvement of these mediators in this obstetric disorder...
Cytokine production in Linomide-treated nod mice and the potential role of a Th (1)/Th(2) shift on autoimmune and anti-inflammatory processesLola Weiss
Departments of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah University Hospital, Jerusalem, Israel
Cytokine 19:85-93. 2002
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Evaluation of urine CYFRA 21-1 for the detection of primary and recurrent bladder carcinomaBenjamin Nisman
Department of Oncology, Hadassah University Hospital, Jerusalem, Israel
Cancer 94:2914-22. 2002
..The urinary concentration of soluble cytokeratin 19 fragments, measured by the CYFRA 21-1 assay, may be used for the noninvasive, early detection of bladder carcinoma...
The relationship of plasminogen activator inhibitor-1 levels to the ST deviation pattern of acute myocardial infarctionDavid Rott
Department of Medicine, Hadassah Hebrew University Medical Center, Jerusalem, Israel
Cardiology 112:56-9. 2009
..We sought to determine whether there are differences in plasma levels of PAI-1, CRP, SAA or IL-6 in patients with STEMI compared to patients with NSTEMI...
Prognostic factors for survival in metastatic breast cancer during first-line paclitaxel chemotherapyBenjamin Nisman
Immunology Laboratory for Tumor Diagnosis, Department of Oncology, Hadassah University Hospital, POB 12000, Jerusalem 91120, Israel
Anticancer Res 23:1939-42. 2003
..2 months and 5.7 months, respectively). Following the first-line paclitaxel treatment the estimates of tumor response became the major predictor of survival (RR-12.3; p < 0.0001)...
Effect of Traumeel S on cytokine profile in a cecal ligation and puncture (CLP) sepsis model in ratsMenachem Oberbaum
The Center for Integrative Complementary Medicine, Shaare Zedek Medical Center, Jerusalem, Israel
J Altern Complement Med 17:909-13. 2011
..The complex homeopathic remedy Traumeel S has been shown to have both anti-inflammatory and immunostimulatory effects in the in vitro setting...
Tumor necrosis factor-alpha blocking agent as a treatment for nephrotic syndromeDavid Raveh
Division of Internal Medicine, Shaare Zedek Medical Center, Jerusalem, Israel
Pediatr Nephrol 19:1281-4. 2004
..Serial serum levels of tumor necrosis factor (TNF)-alpha are shown and discussed. We suggest studying the TNF-alpha blocking agents as optional treatment for nephrotic syndrome...
Interleukin-6 and N-terminal pro-brain natriuretic peptide cord blood levels in premature infants: correlations with perinatal variablesIlan Arad
Department of Neonatology, Hadassah Medical Center and Hebrew University Medical School, Jerusalem, Israel
Isr Med Assoc J 12:419-23. 2010
..Elevated cord blood levels of interleukin-6 and N-terminal pro-brain natriuretic peptide were associated with neonatal complications; however, simultaneously obtained values have not been compared to date...
The involvement of IL-6 and IL-8 in acute invasive gastroenteritis of childrenNachum Vaisman
Unit of Clinical Nutrition, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv 64239, Israel
Cytokine 22:194-7. 2003
..The difference in IL-6, and to a lesser degree IL-8, between proven and non-proven bacterial etiologies, needs further investigation...
Increased Th1 and Th2 type cytokine production in patients with active tuberculosisZeev T Handzel
Pediatric Research Institute, Kaplan Medical Center, Rehovot, Israel
Isr Med Assoc J 9:479-83. 2007
..Previous immune studies in young Ethiopian immigrants to Israel did not demonstrate anergy to purified protein derivative or a Th2-like cytokine profile...
Cytokines and C-reactive protein production in hip-fracture-operated elderly patientsYichayaou Beloosesky
Department of Geriatrics, Rabin Medical Center, Beilinson Campus, Petach Tikvah, Israel
J Gerontol A Biol Sci Med Sci 62:420-6. 2007
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The effect of fish oil supplementation on cytokine production in childrenNachum Vaisman
Unit of Clinical Nutrition, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv 64239, Israel
Eur Cytokine Netw 16:194-8. 2005
..In conclusion, our results indicate an increased production of both pro-inflammatory and anti-inflammatory cytokines, with and without LPS stimulation, in children on 12 weeks' n-3 PUFA supplementation...
Novel biomarkers in autoimmune diseases: prolactin, ferritin, vitamin D, and TPA levels in autoimmune diseasesHedi Orbach
Department of Medicine B, Wolfson Medical Center, Holon, Israel
Ann N Y Acad Sci 1109:385-400. 2007
..Hyperferritinemia may be used as an acute-phase reactant marker in autoimmune diseases mainly SLE. TPA may be used to indicate the tendency for malignancies...
Changes in cytokine production and impaired hematopoiesis in patients with anorexia nervosa: the effect of refeedingNachum Vaisman
Clinical Nutrition Unit, Sourasky Tel Aviv Medical Center, 6 Weizmann Street, Tel Aviv 64239, Israel
Cytokine 26:255-61. 2004
..The changes in the levels of hormones and cytokines known to be involved in hematopoiesis along refeeding may suggest a role for these factors in anorexia nervosa...
Impact of treatment with infliximab on serum cytokine profile of patients with rheumatoid and psoriatic arthritisHoward Amital
Department of Medicine D, Meir Medical Center, Tshernichovsky 59, Kfar Saba, 44281, Israel
Ann N Y Acad Sci 1110:649-60. 2007
..In an unselected population of RA and PsA patients, we noticed diverse patterns of serum cytokine profiles. These results imply that the cytokine profiles of RA and PsA are diverse and their pathogenesis is heterogeneous...
PLIF induces IL-10 production in monocytes: a calmodulin-p38 mitogen-activated protein kinase-dependent pathwayMuayad A Zahalka
Laboratory of Molecular Immunology, Felsenstein Medical Research Center, Sackler School of Medicine, Tel Aviv University, Rabin Medical Center, Petach-Tikva 49100, Israel
FASEB J 17:955-7. 2003
..However, extracellular signal-related kinases1,2 (ERK1,2), also activated by C48 stimulation, exhibited a limiting effect on IL-10 production...
Regulation of vascular endothelial growth factor-A and its soluble receptor sFlt-1 by luteinizing hormone in vivo: implication for ovarian follicle angiogenesisGuy Gutman
Sara Racine IVF Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Fertil Steril 89:922-6. 2008
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