Rubhana Raqib

Summary

Affiliation: International Centre for Diarrhoeal Disease Research
Country: Bangladesh

Publications

  1. pmc Use of antibodies in lymphocyte secretions for detection of subclinical tuberculosis infection in asymptomatic contacts
    Rubhana Raqib
    ICDDR, B Centre for Health and Population Research, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh
    Clin Diagn Lab Immunol 11:1022-7. 2004
  2. ncbi Low birth weight is associated with altered immune function in rural Bangladeshi children: a birth cohort study
    Rubhana Raqib
    International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka, Bangladesh
    Am J Clin Nutr 85:845-52. 2007
  3. pmc Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic
    Rubhana Raqib
    International Centre for Diarrhoeal Disease Research Bangladesh, Centre for Health and Population Research, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 103:9178-83. 2006
  4. doi Effects of in utero arsenic exposure on child immunity and morbidity in rural Bangladesh
    Rubhana Raqib
    International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    Toxicol Lett 185:197-202. 2009
  5. pmc Pharmacokinetics of a single oral dose of vitamin D3 (70,000 IU) in pregnant and non-pregnant women
    Daniel E Roth
    Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Nutr J 11:114. 2012
  6. pmc Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial
    Rubhana Raqib
    International Centre for Diarrheal Disease Research, Dhaka, Bangladesh
    BMC Infect Dis 12:111. 2012
  7. pmc A systemic downregulation of gamma interferon production is associated with acute shigellosis
    R Raqib
    Division of Clinical Bacteriology, Karolinska Institutet, Huddinge University Hospital, Sweden
    Infect Immun 65:5338-41. 1997
  8. doi Nutrition, immunology, and genetics: future perspectives
    Rubhana Raqib
    Nutritional Biochemistry Laboratory, Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh
    Nutr Rev 67:S227-36. 2009
  9. ncbi Zinc supplementation of pregnant rats with adequate zinc nutriture suppresses immune functions in their offspring
    Rubhana Raqib
    International Centre for Diarrhoeal Diseases Research, Bangladesh, Dhaka 1212, Bangladesh
    J Nutr 137:1037-42. 2007
  10. pmc Detection of antibodies secreted from circulating Mycobacterium tuberculosis-specific plasma cells in the diagnosis of pediatric tuberculosis
    Rubhana Raqib
    International Centre for Diarrheal Disease and Research, Bangladesh
    Clin Vaccine Immunol 16:521-7. 2009

Detail Information

Publications48

  1. pmc Use of antibodies in lymphocyte secretions for detection of subclinical tuberculosis infection in asymptomatic contacts
    Rubhana Raqib
    ICDDR, B Centre for Health and Population Research, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh
    Clin Diagn Lab Immunol 11:1022-7. 2004
    ..The method may also allow discrimination between effective treatment of active infection and suboptimal response to therapy...
  2. ncbi Low birth weight is associated with altered immune function in rural Bangladeshi children: a birth cohort study
    Rubhana Raqib
    International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka, Bangladesh
    Am J Clin Nutr 85:845-52. 2007
    ..Recent studies have shown that such exposure early in life may have long-term implications for later immunocompetence and susceptibility to infectious diseases...
  3. pmc Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic
    Rubhana Raqib
    International Centre for Diarrhoeal Disease Research Bangladesh, Centre for Health and Population Research, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 103:9178-83. 2006
    ....
  4. doi Effects of in utero arsenic exposure on child immunity and morbidity in rural Bangladesh
    Rubhana Raqib
    International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    Toxicol Lett 185:197-202. 2009
    ..The effect seemed to be partially gender dependent. Arsenic exposure also affected breast milk content of trophic factors and maternal morbidity...
  5. pmc Pharmacokinetics of a single oral dose of vitamin D3 (70,000 IU) in pregnant and non-pregnant women
    Daniel E Roth
    Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Nutr J 11:114. 2012
    ..To inform the design of prenatal vitamin D3 trials, we conducted a pharmacokinetic study of single-dose vitamin D3 supplementation in women of reproductive age...
  6. pmc Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial
    Rubhana Raqib
    International Centre for Diarrheal Disease Research, Dhaka, Bangladesh
    BMC Infect Dis 12:111. 2012
    ..Here, we aimed to evaluate whether butyrate can be used as an adjunct to antibiotics in the treatment of shigellosis in patients...
  7. pmc A systemic downregulation of gamma interferon production is associated with acute shigellosis
    R Raqib
    Division of Clinical Bacteriology, Karolinska Institutet, Huddinge University Hospital, Sweden
    Infect Immun 65:5338-41. 1997
    ..01). Constitutive IFN-gamma production in Bangladeshi controls was significantly upregulated compared to that in Swedish controls...
  8. doi Nutrition, immunology, and genetics: future perspectives
    Rubhana Raqib
    Nutritional Biochemistry Laboratory, Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh
    Nutr Rev 67:S227-36. 2009
    ....
  9. ncbi Zinc supplementation of pregnant rats with adequate zinc nutriture suppresses immune functions in their offspring
    Rubhana Raqib
    International Centre for Diarrhoeal Diseases Research, Bangladesh, Dhaka 1212, Bangladesh
    J Nutr 137:1037-42. 2007
    ..Zn supplementation of ZC dams induced immunosuppressive effects in utero that may also be mediated through milk and persist in the offspring after weaning...
  10. pmc Detection of antibodies secreted from circulating Mycobacterium tuberculosis-specific plasma cells in the diagnosis of pediatric tuberculosis
    Rubhana Raqib
    International Centre for Diarrheal Disease and Research, Bangladesh
    Clin Vaccine Immunol 16:521-7. 2009
    ..001). The ALS assay is a novel diagnostic method with potential applications in the diagnosis of pediatric TB and in subsequent monitoring of treatment effectiveness...
  11. pmc Innate immune responses in children and adults with Shigellosis
    R Raqib
    Laboratory Sciences Division, International Centre for Diarrhoeal Diseases Research, Bangladesh, Dhaka, Bangladesh
    Infect Immun 68:3620-9. 2000
    ..In addition, increased production of proinflammatory mediators in the rectum of patients with severe histology suggested contribution of these molecules to the immunopathogenesis of severe colitis caused by shigellae...
  12. ncbi Delayed and reduced adaptive humoral immune responses in children with shigellosis compared with in adults
    R Raqib
    International Centre for Diarrhoeal Diseases Research, ICDDR, B, Dhaka, Bangladesh
    Scand J Immunol 55:414-23. 2002
    ..Thus, paediatric patients with shigellosis have reduced and delayed adaptive immune responses compared with adult patients...
  13. pmc Apoptosis in acute shigellosis is associated with increased production of Fas/Fas ligand, perforin, caspase-1, and caspase-3 but reduced production of Bcl-2 and interleukin-2
    Rubhana Raqib
    International Centre for Diarrhoeal Diseases Research, Bangladesh, Dhaka, Bangladesh
    Infect Immun 70:3199-207. 2002
    ..dysenteriae type 1 infection was associated with a significant up-regulation of Fas/Fas-L and perforin and granzyme A expression and a down-regulation of Bcl-2 and IL-2, which promote cell survival...
  14. pmc Persistence of mucosal mast cells and eosinophils in Shigella-infected children
    Rubhana Raqib
    International Centre for Diarrhoeal Diseases Research, Bangladesh, Dhaka, Bangladesh
    Infect Immun 71:2684-92. 2003
    ..The results suggest that children with shigellosis have a persistent activation of the innate immune response in the convalescent phase, indicating delayed elimination of Shigella antigens compared to adults...
  15. ncbi Rapid diagnosis of active tuberculosis by detecting antibodies from lymphocyte secretions
    Rubhana Raqib
    International Center for Diarrhoeal Disease Research, Bangladesh
    J Infect Dis 188:364-70. 2003
    ..Patients with active TB had higher BCG- or PPD-specific IgG antibody responses than patients without TB or healthy subjects (P=.001). This method can be used as a quick diagnostic aid to facilitate rapid detection of TB cases...
  16. ncbi Effect of zinc supplementation on immune and inflammatory responses in pediatric patients with shigellosis
    Rubhana Raqib
    International Centre for Diarrhoeal Diseases Research, Bangladesh ICDDR, B Centre for Health and Population Research, Dhaka, Bangladesh
    Am J Clin Nutr 79:444-50. 2004
    ..Prolonged zinc supplementation also improves cell-mediated immunity in severely malnourished children...
  17. ncbi Effects of zinc supplementation as adjunct therapy on the systemic immune responses in shigellosis
    Muhammad J Rahman
    International Centre for Health and Population Research, Bangladesh, Dhaka, Bangladesh
    Am J Clin Nutr 81:495-502. 2005
    ..Zinc is lost during diarrheal diseases, and zinc deficiency induces intestinal morphology-altering inflammatory responses that zinc supplementation can correct...
  18. pmc Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis
    Akhirunnesa Mily
    International Centre for Diarrheal Disease Research, Bangladesh ICDDR, B, Mohakhali, Dhaka 1212, Bangladesh
    BMC Pulm Med 13:23. 2013
    ..We aimed to evaluate a therapeutic dose of PB alone or in combination with vitamin D3 for induction of LL-37 expression in immune cells and enhancement of antimycobacterial activity in monocyte-derived macrophages (MDM)...
  19. pmc Phenylbutyrate counteracts Shigella mediated downregulation of cathelicidin in rabbit lung and intestinal epithelia: a potential therapeutic strategy
    Protim Sarker
    International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh
    PLoS ONE 6:e20637. 2011
    ..Oral treatment of Shigella infected rabbits with sodium butyrate (NaB) reduces clinical severity and counteracts the downregulation of cathelicidin (CAP-18) in the large intestinal epithelia...
  20. pmc Increased levels of inflammatory mediators in children and adults infected with Vibrio cholerae O1 and O139
    Firdausi Qadri
    Centre for Health and Population Research, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Clin Diagn Lab Immunol 9:221-9. 2002
    ..cholerae O1 and O139...
  21. doi In utero arsenic exposure is associated with impaired thymic function in newborns possibly via oxidative stress and apoptosis
    Sultan Ahmed
    Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden
    Toxicol Sci 129:305-14. 2012
    ..In conclusion, prenatal arsenic exposure was associated with reduced thymic function, possibly via induction of oxidative stress and apoptosis, suggesting subsequent immunosuppression in childhood...
  22. doi Treatment with phenylbutyrate in a pre-clinical trial reduces diarrhea due to enteropathogenic Escherichia coli: link to cathelicidin induction
    Abdullah Al-Mamun
    International Centre for Diarrhoeal Disease Research, Bangladesh, 1212 Dhaka, Bangladesh
    Microbes Infect 15:939-50. 2013
    ..Upregulation of CAP-18 in the epithelia was accompanied by healing of the epithelial lining, reduced shedding and virulence of EPEC and recovery from diarrhea. ..
  23. pmc Sex-specific effects of early life cadmium exposure on DNA methylation and implications for birth weight
    Maria Kippler
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Epigenetics 8:494-503. 2013
    ..This is consistent with previous findings of sex-specific cadmium toxicity. Cadmium-related changes in methylation were also related to lower birth weight. ..
  24. doi Environmental exposure to arsenic and cadmium during pregnancy and fetal size: a longitudinal study in rural Bangladesh
    Maria Kippler
    Institute of Environmental Medicine, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Reprod Toxicol 34:504-11. 2012
    ..In conclusion, particularly Cd, but also As, appeared to influence fetal development in a sex-dependent manner...
  25. pmc Arsenic-associated oxidative stress, inflammation, and immune disruption in human placenta and cord blood
    Sultan Ahmed
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Environ Health Perspect 119:258-64. 2011
    ..Arsenic (As) exposure during pregnancy induces oxidative stress and increases the risk of fetal loss and low birth weight...
  26. doi Prenatal zinc supplementation of zinc-adequate rats adversely affects immunity in offspring
    Mohammad T K Sharkar
    International Centre for Diarrhoeal Diseases Research, Bangladesh, Dhaka 1212, Bangladesh
    J Nutr 141:1559-64. 2011
    ..08). In conclusion, prenatal Zn exposure increases serum Zn levels in pups and suppresses antigen-specific proliferation and antibody responses and APC function, whereas postnatal exposure may suppress the mucosal immune reservoir...
  27. pmc Validation of the ALS assay in adult patients with culture confirmed pulmonary tuberculosis
    Rokeya Sultana Rekha
    International Centre for Diarrhoeal Diseases Research, Bangladesh, Dhaka, Bangladesh
    PLoS ONE 6:e16425. 2011
    ..We have earlier shown that Bacille Calmette-Guérin (BCG) vaccine-specific IgG Antibodies in Lymphocyte Supernatant (ALS) can be used for diagnosis of active tuberculosis (TB) in adults and children...
  28. pmc Differential host immune responses to epidemic and endemic strains of Shigella dysenteriae type I
    Mohammad Abu Sayem
    Laboratory Sciences Division, ICDDR, B, GPO Box 128, Dhaka 1000, Bangladesh
    J Health Popul Nutr 29:429-37. 2011
    ..dysenteriae type 1 strains. Part of this variation may be attributed to the differential complexity of protein/peptide antigens...
  29. pmc Arsenic exposure affects plasma insulin-like growth factor 1 (IGF-1) in children in rural Bangladesh
    Sultan Ahmed
    Centre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh Institute of Environmental Medicine IMM, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e81530. 2013
    ..The aim of the study was to assess the effects of As exposure on child growth parameters to evaluate causal associations...
  30. pmc BCG-specific IgG-secreting peripheral plasmablasts as a potential biomarker of active tuberculosis in HIV negative and HIV positive patients
    Senait Ashenafi
    Department of Medicine, Center for Infectious Medicine CIM, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Thorax 68:269-76. 2013
    ..In this study, assessment of BCG-specific IgG-secreting peripheral plasmablasts, was used to identify active TB in these high-risk groups...
  31. doi Arsenic exposure and cell-mediated immunity in pre-school children in rural Bangladesh
    Sultan Ahmed
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden Centre for Vaccine Sciences, International Centre for Diarrheal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    Toxicol Sci 141:166-75. 2014
    ..These associations were particularly strong in children with recent infections. In conclusion, elevated childhood arsenic exposure appeared to reduce cell-mediated immunity, possibly linked to reduced concentrations of Th1 cytokines. ..
  32. doi The effect of exclusive breast-feeding on respiratory illness in young infants in a maternal immunization trial in Bangladesh
    Emily Henkle
    Center for Health Research Northwest, Kaiser Permanente, Portland, OR, USA
    Pediatr Infect Dis J 32:431-5. 2013
    ..We evaluated the effect of exclusive breast-feeding on respiratory illness with fever (RIF) in Bangladeshi infants in the context of a randomized maternal influenza immunization trial...
  33. doi Molecular mechanism of rifampicin and isoniazid resistance in Mycobacterium tuberculosis from Bangladesh
    Zeaur Rahim
    International Centre for Diarrheal Disease Research, Bangladesh, Bangladesh
    Tuberculosis (Edinb) 92:529-34. 2012
    ..This study provides basic data for the construction of low cost tailor-made molecular system for rapid diagnosis of MDR-TB in Bangladesh...
  34. doi Safety, dose, immunogenicity, and transmissibility of an oral live attenuated Shigella flexneri 2a vaccine candidate (SC602) among healthy adults and school children in Matlab, Bangladesh
    Kazi Mizanur Rahman
    ICDDR, B, Mohakhali, Dhaka 1212, Bangladesh
    Vaccine 29:1347-54. 2011
    ..None of the volunteers developed diarrhea. Overall, SC602 was found to be associated with minimal vaccine shedding, minimal reactogenicity, no transmission risk, and low immune stimulation...
  35. doi Pregnancy and the methyltransferase genotype independently influence the arsenic methylation phenotype
    Renee M Gardner
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Pharmacogenet Genomics 22:508-16. 2012
    ..The aim of this study was to evaluate the relative contribution of the methyltransferase genotype and pregnancy to the arsenic metabolism phenotype...
  36. doi Effectiveness of maternal influenza immunization in mothers and infants
    K Zaman
    International Centre for Diarrheal Disease Research, Dhaka, Bangladesh
    N Engl J Med 359:1555-64. 2008
    ..We assessed the clinical effectiveness of inactivated influenza vaccine administered during pregnancy in Bangladesh...
  37. pmc Assessment of population structure and major circulating phylogeographical clades of Mycobacterium tuberculosis complex in Bangladesh suggests a high prevalence of a specific subclade of ancient M. tuberculosis genotypes
    Zeaur Rahim
    International Centre for Diarrhoeal Disease Research, Bangladesh, Center for Health and Population Research, Dhaka, Bangladesh
    J Clin Microbiol 45:3791-4. 2007
    ..0%]) and PGG 2 and 3 (25%). Forty-nine strains with a new spoligotype signature and considered as south or southeast Asian-linked emerging clones were designated as "Matlab type."..
  38. doi The effect of newborn vitamin A supplementation on infant immune functions: trial design, interventions, and baseline data
    Shaikh Meshbahuddin Ahmad
    Center for Vaccine Sciences, ICDDR, B, Mohakhali, Dhaka 1212, Bangladesh Electronic address
    Contemp Clin Trials 39:269-79. 2014
    ..Connecting different aspects of immunological data in early infancy will help elucidate immune competence for protecting infection. Trial registration ClinicalTrials.gov: NCT01583972...
  39. doi Prenatal vitamin D₃ supplementation suppresses LL-37 peptide expression in ex vivo activated neonatal macrophages but not their killing capacity
    Rubhana Raqib
    Nutritional Biochemistry Laboratory, Centre for Vaccine Sciences, International Centre for Diarrheal Disease Research, Bangladesh ICDDR, B, Mohakhali, 1212Dhaka, Bangladesh
    Br J Nutr 112:908-15. 2014
    ..A weekly dose of 0·875 mg vitD₃ to healthy pregnant women suppressed the intracellular LL-37 peptide stores of activated macrophages, but did not significantly affect the ex vivo bactericidal capacity of cord blood MDM...
  40. pmc The effect of postpartum vitamin A supplementation on breast milk immune regulators and infant immune functions: study protocol of a randomized, controlled trial
    Shaikh Meshbahuddin Ahmad
    Center for Vaccine Sciences, ICDDR, B, Mohakhali, Dhaka, 1212, Bangladesh
    Trials 16:129. 2015
    ..However, breast milk contains numerous immune-protective components that are important for infant immune development, and several of these components are regulated by vitamin A...
  41. pmc Stool microbiota and vaccine responses of infants
    M Nazmul Huda
    US Department of Agriculture Western Human Nutrition Research Center, Davis California International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh and
    Pediatrics 134:e362-72. 2014
    ..Oral vaccine efficacy is low in less-developed countries, perhaps due to intestinal dysbiosis. This study determined if stool microbiota composition predicted infant oral and parenteral vaccine responses...
  42. pmc Chronic respiratory symptoms in children following in utero and early life exposure to arsenic in drinking water in Bangladesh
    Allan H Smith
    Arsenic Health Effects Research Program, School of Public Health, University of California, Berkeley, CA, USA, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh, Department of Medicine, University of California, San Francisco, CA, USA, Department of Community Health Sciences, Fielding School of Public Health, University of California, Los Angeles, CA, USA, Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA and Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, Oakland, CA, USA
    Int J Epidemiol 42:1077-86. 2013
    ..Arsenic exposure via drinking water increases the risk of chronic respiratory disease in adults. However, information on pulmonary health effects in children after early life exposure is limited...
  43. pmc A prospective study of the prevalence of tuberculosis and bacteraemia in Bangladeshi children with severe malnutrition and pneumonia including an evaluation of Xpert MTB/RIF assay
    Mohammod Jobayer Chisti
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh Centre for International Child Health, The University of Melbourne Department of Paediatrics and Murdoch Childrens Research Institute, Royal Children s Hospital, Melbourne, Australia
    PLoS ONE 9:e93776. 2014
    ..Severe malnutrition is a risk factor for pneumonia due to a wide range of pathogens but aetiological data are limited and the role of Mycobacterium tuberculosis is uncertain...
  44. pmc Changing emergence of Shigella sero-groups in Bangladesh: observation from four different diarrheal disease hospitals
    Sumon Kumar Das
    Centre for Nutrition and Food Security CNFS, International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    PLoS ONE 8:e62029. 2013
    ..Shigellosis continues to be a public health challenge for developing countries, including Bangladesh. The aim of the study is to demonstrate recent changes in Shigella sero-groups and their geographical diversity...
  45. doi Accumulation of cadmium in human placenta interacts with the transport of micronutrients to the fetus
    Maria Kippler
    Institute of Environmental Medicine, Division of Metals and Health, Karolinska Institutet, Stockholm, Sweden
    Toxicol Lett 192:162-8. 2010
    ..In conclusion, the Cd concentrations in placenta were clearly elevated, which seemed to impair Zn transfer to the fetus. Induction of MT explained the placental accumulation of Cd, but not the impairment of Zn transport...
  46. doi On birth single dose live attenuated OPV and BCG vaccination induces gut cathelicidin LL37 responses at 6 week of age: a natural experiment
    Md Jahangir Alam
    Center for Vaccine Sciences, ICDDR, B, Mohakhali, Dhaka 1212, Bangladesh
    Vaccine 33:18-21. 2015
    ..The result also suggests that in polio endemic area, exclusive breastfeeding may be sufficient for mucosal anti-polio responses during early infancy. ..
  47. pmc Operational feasibility of using loop-mediated isothermal amplification for diagnosis of pulmonary tuberculosis in microscopy centers of developing countries
    Catharina C Boehme
    Foundation for Innovative New Diagnostics, 1216 Cointrin, Switzerland
    J Clin Microbiol 45:1936-40. 2007
    ..Technicians with no prior molecular experience easily performed the assay after 1 week of training, and opportunities for further simplification of the assay were identified...
  48. pmc Immunoproteome analysis of soluble and membrane proteins of Shigella flexneri 2457T
    Amy V Jennison
    School of Biochemistry and Molecular Biology, Faculty of Science, The Australian National University, Canberra, ACT 0200, Australia
    World J Gastroenterol 12:6683-8. 2006
    ..To profile the immunogenic proteins of Shigella flexneri (S. flexneri) expressed during human infection using a proteomic approach...