Abu SG Faruque

Summary

Affiliation: International Centre for Diarrhoeal Disease Research
Country: Bangladesh

Publications

  1. pmc Self-limiting nature of seasonal cholera epidemics: Role of host-mediated amplification of phage
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 102:6119-24. 2005
  2. ncbi Role of phages in the epidemiology of cholera
    Shah M Faruque
    Centre for Food and Water Borne Diseases, International Centre for Diarrhoeal Disease Research, Bangladesh, 68, Shaheed Tajuddin Ahmed Sharani, Mohakhali, 1212, Dhaka, Bangladesh
    Curr Top Microbiol Immunol 379:165-80. 2014
  3. pmc Satellite phage TLCφ enables toxigenic conversion by CTX phage through dif site alteration
    Faizule Hassan
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Nature 467:982-5. 2010
  4. pmc An experimental study of phage mediated bactericidal selection & emergence of the El Tor Vibrio cholerae
    M Shamim Hasan Zahid
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Indian J Med Res 133:218-24. 2011
  5. pmc Phage-bacterial interactions in the evolution of toxigenic Vibrio cholerae
    Shah M Faruque
    Centre for Food and Waterborne Diseases, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Virulence 3:556-65. 2012
  6. pmc Typing of human rotaviruses: nucleotide mismatches between the VP7 gene and primer are associated with genotyping failure
    Mustafizur Rahman
    ICDDR, B Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
    Virol J 2:24. 2005
  7. ncbi An improved technique for isolation of environmental Vibrio cholerae with epidemic potential: monitoring the emergence of a multiple-antibiotic-resistant epidemic strain in Bangladesh
    Shah M Faruque
    Molecular Genetics Laboratory, Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    J Infect Dis 193:1029-36. 2006
  8. pmc Isolation of Shigella dysenteriae type 1 and S. flexneri strains from surface waters in Bangladesh: comparative molecular analysis of environmental Shigella isolates versus clinical strains
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Appl Environ Microbiol 68:3908-13. 2002
  9. pmc Transmissibility of cholera: in vivo-formed biofilms and their relationship to infectivity and persistence in the environment
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 103:6350-5. 2006
  10. pmc Pathogenic potential of environmental Vibrio cholerae strains carrying genetic variants of the toxin-coregulated pilus pathogenicity island
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Infect Immun 71:1020-5. 2003

Collaborators

Detail Information

Publications63

  1. pmc Self-limiting nature of seasonal cholera epidemics: Role of host-mediated amplification of phage
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 102:6119-24. 2005
    ..cholerae and, hence, the collapse of the epidemic. Thus, in vivo phage amplification in patients and subsequent phage predation in the environment may explain the self-limiting nature of seasonal cholera epidemics in Bangladesh...
  2. ncbi Role of phages in the epidemiology of cholera
    Shah M Faruque
    Centre for Food and Water Borne Diseases, International Centre for Diarrhoeal Disease Research, Bangladesh, 68, Shaheed Tajuddin Ahmed Sharani, Mohakhali, 1212, Dhaka, Bangladesh
    Curr Top Microbiol Immunol 379:165-80. 2014
    ..Phages have been shown to play a crucial role in modulating cholera epidemics, and enhance V. cholerae evolution through a bactericidal selection process which favors the emergence of new clones. ..
  3. pmc Satellite phage TLCφ enables toxigenic conversion by CTX phage through dif site alteration
    Faizule Hassan
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Nature 467:982-5. 2010
    ..These results reveal a remarkable level of cooperative interactions between multiple filamentous phages in the emergence of the bacterial pathogen that causes cholera...
  4. pmc An experimental study of phage mediated bactericidal selection & emergence of the El Tor Vibrio cholerae
    M Shamim Hasan Zahid
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Indian J Med Res 133:218-24. 2011
    ..Here we describe an environmental bacteriophage designated JSF9 which might have contributed to the range of factors...
  5. pmc Phage-bacterial interactions in the evolution of toxigenic Vibrio cholerae
    Shah M Faruque
    Centre for Food and Waterborne Diseases, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    Virulence 3:556-65. 2012
    ..cholerae includes, among other factors, phages that either participate in horizontal gene transfer or in a bactericidal selection process favoring the emergence of new clones of V. cholerae...
  6. pmc Typing of human rotaviruses: nucleotide mismatches between the VP7 gene and primer are associated with genotyping failure
    Mustafizur Rahman
    ICDDR, B Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
    Virol J 2:24. 2005
    ..9%) of the rotavirus strains isolated in 2002 could not be G-typed using the routinely used primer set. To investigate the reason why the strains were untypeable, nucleotide sequencing of the VP7 genes was performed...
  7. ncbi An improved technique for isolation of environmental Vibrio cholerae with epidemic potential: monitoring the emergence of a multiple-antibiotic-resistant epidemic strain in Bangladesh
    Shah M Faruque
    Molecular Genetics Laboratory, Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
    J Infect Dis 193:1029-36. 2006
    ..cholerae occurs in the human host and leads to the start of an epidemic cycle dominated by a single clone of V. cholerae that spreads rapidly through environmental waters...
  8. pmc Isolation of Shigella dysenteriae type 1 and S. flexneri strains from surface waters in Bangladesh: comparative molecular analysis of environmental Shigella isolates versus clinical strains
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Appl Environ Microbiol 68:3908-13. 2002
    ....
  9. pmc Transmissibility of cholera: in vivo-formed biofilms and their relationship to infectivity and persistence in the environment
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 103:6350-5. 2006
    ..The results of this study support a model of cholera transmission in which in vivo-formed biofilms contribute to enhanced infectivity and environmental persistence of pathogenic V. cholerae...
  10. pmc Pathogenic potential of environmental Vibrio cholerae strains carrying genetic variants of the toxin-coregulated pilus pathogenicity island
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Infect Immun 71:1020-5. 2003
    ..cholerae encode biologically active gene products. Detection of functional homologs of the TCP island genes in environmental strains may have implications for understanding the origin and evolution of virulence genes of V. cholerae...
  11. pmc Shigella dysenteriae type 1-specific bacteriophage from environmental waters in Bangladesh
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Appl Environ Microbiol 69:7028-31. 2003
    ..dysenteriae type 1 was isolated from three phage-positive samples. The results of this study suggest that phage SF-9 may have epidemiological applications in tracing the presence of S. dysenteriae type 1 in environmental waters...
  12. pmc Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 101:2123-8. 2004
    ..cholerae strains and thus promotes the rare, multiple-gene transfer events needed to assemble the critical combination of genes required for pandemic spread...
  13. ncbi Genetics of stress adaptation and virulence in toxigenic Vibrio cholerae
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    DNA Cell Biol 23:723-41. 2004
    ..cholerae involves a combination of selection mechanisms both in the host and in the environment. The occurrence of periodic epidemics of cholera in endemic areas appear to enhance this process...
  14. pmc Genomic analysis of the Mozambique strain of Vibrio cholerae O1 reveals the origin of El Tor strains carrying classical CTX prophage
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 104:5151-6. 2007
    ....
  15. pmc Genomic sequence and receptor for the Vibrio cholerae phage KSF-1phi: evolutionary divergence among filamentous vibriophages mediating lateral gene transfer
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrheal Disease Research, Bangladesh, Dhaka
    J Bacteriol 187:4095-103. 2005
    ..Since MSHA is present in a wide variety of V. cholerae strains and is presumed to express in the environment, diverse filamentous phages using this receptor are likely to contribute significantly to V. cholerae evolution...
  16. pmc CTXphi-independent production of the RS1 satellite phage by Vibrio cholerae
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 100:1280-5. 2003
    ..cholerae strains. This study also shows that filamentous phages can package diverse DNA elements and thus may play a role in horizontal transfer of more genes than previously appreciated...
  17. pmc Diminished diarrheal response to Vibrio cholerae strains carrying the replicative form of the CTX(Phi) genome instead of CTX(Phi) lysogens in adult rabbits
    S M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Infect Immun 69:6084-90. 2001
    ..cholerae vaccine candidates impaired in chromosomal integration of CTX(Phi). These findings may also contribute to understanding of the etiology of diarrhea occasionally associated with nontoxigenic V. cholerae strains...
  18. pmc RS1 element of Vibrio cholerae can propagate horizontally as a filamentous phage exploiting the morphogenesis genes of CTXphi
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Infect Immun 70:163-70. 2002
    ..The results of this study showed for the first time that RS1 element, which encodes a site-specific recombination system in V. cholerae, can propagate horizontally as a filamentous phage, exploiting the morphogenesis genes of CTXPhi...
  19. pmc Induction of the lysogenic phage encoding cholera toxin in naturally occurring strains of toxigenic Vibrio cholerae O1 and O139
    S M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Infect Immun 66:3752-7. 1998
    ....
  20. pmc Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae
    S M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Microbiol Mol Biol Rev 62:1301-14. 1998
    ..The ecosystem comprising V. cholerae, CTXPhi, the aquatic environment, and the mammalian host offers an understanding of the complex relationship between pathogenesis and the natural selection of a pathogen...
  21. ncbi The O139 serogroup of Vibrio cholerae comprises diverse clones of epidemic and nonepidemic strains derived from multiple V. cholerae O1 or non-O1 progenitors
    S M Faruque
    Molecular Genetics Laboratory, Laboratory Sciences Division, ICDDRB, Dhaka 1000, Bangladesh
    J Infect Dis 182:1161-8. 2000
    ..Thus, the O139 antigen is present in different lineages, and this serogroup appears to comprise epidemic and nonepidemic strains derived separately from different progenitors...
  22. pmc Analysis of clinical and environmental strains of nontoxigenic Vibrio cholerae for susceptibility to CTXPhi: molecular basis for origination of new strains with epidemic potential
    S M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Infect Immun 66:5819-25. 1998
    ..cholerae are more likely to possess the TCP pathogenicity island and hence to be infected by CTXPhi, leading to the origination of potential new epidemic clones...
  23. pmc Sunlight-induced propagation of the lysogenic phage encoding cholera toxin
    S M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Infect Immun 68:4795-801. 2000
    ..cholerae...
  24. pmc Molecular characterization of a new ribotype of Vibrio cholerae O139 Bengal associated with an outbreak of cholera in Bangladesh
    S M Faruque
    Molecular Genetics Laboratory, Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    J Clin Microbiol 37:1313-8. 1999
    ..6-kb region of the SXT element in strains which were susceptible to the antibiotics. Thus, V. cholerae O139 strains in Bangladesh are also undergoing considerable reassortments in genetic elements encoding antimicrobial resistance...
  25. pmc Lysogenic conversion of environmental Vibrio mimicus strains by CTXPhi
    S M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    Infect Immun 67:5723-9. 1999
    ..The results of this study also supported the existence of a TCP-independent mechanism for infection by CTXPhi and showed that at least one species of Vibrio other than V. cholerae may contribute to the propagation of the phage...
  26. pmc Molecular analysis of toxigenic Vibrio cholerae O139 Bengal strains isolated in Bangladesh between 1993 and 1996: evidence for emergence of a new clone of the Bengal vibrios
    S M Faruque
    Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka
    J Clin Microbiol 35:2299-306. 1997
    ..Thus, strains belonging to the O139 serogroup may have emerged from similar serotype-specific genetic changes in more than one progenitor strain of V. cholerae...
  27. pmc Emergence of a new clone of toxigenic Vibrio cholerae O1 biotype El Tor displacing V. cholerae O139 Bengal in Bangladesh
    S M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    J Clin Microbiol 35:624-30. 1997
    ..Further studies are required to assess the epidemic potential of the newly emerged clone of V. cholerae O1 and to understand the mechanism of emergence of new clones of toxigenic V. cholerae...
  28. doi El Tor cholera with severe disease: a new threat to Asia and beyond
    A K Siddique
    Public Health Sciences Division PHSD, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Epidemiol Infect 138:347-52. 2010
    ..However, if cholera due to strains with increased severity spread to other areas where treatment facilities are limited, there are likely to be many more cholera deaths...
  29. pmc New variants of Vibrio cholerae O1 biotype El Tor with attributes of the classical biotype from hospitalized patients with acute diarrhea in Bangladesh
    G Balakrish Nair
    Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
    J Clin Microbiol 40:3296-9. 2002
    ..Furthermore, the existence of such novel strains may have implications for the development of a cholera vaccine...
  30. pmc Controlled study of cytolethal distending toxin-producing Escherichia coli infections in Bangladeshi children
    M J Albert
    International Centre for Diarrhoeal Disease Research, Bangladesh
    J Clin Microbiol 34:717-9. 1996
    ..1 versus 0.93%), this difference did not reach statistical significance (P = 0.082). All CDT-positive strains also possessed the virulence factors of enteropathogenic E. coli or enteroaggregative E. coli isolates...
  31. pmc Examination of diverse toxin-coregulated pilus-positive Vibrio cholerae strains fails to demonstrate evidence for Vibrio pathogenicity island phage
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Infect Immun 71:2993-9. 2003
    ..Further studies are necessary to understand the mechanism of horizontal transfer of the TCP island...
  32. pmc Phenotypic and genotypic changes in Vibrio cholerae O139 Bengal
    M J Albert
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka
    J Clin Microbiol 35:2588-92. 1997
    ..cholerae O1 in human infection is not clear. Studies of the environmental factors will provide the key for an understanding of the relative abundance of these vibrios...
  33. pmc Demonstration of a lack of synergistic effect of rotavirus with other diarrheal pathogens on severity of diarrhea in children
    L E Unicomb
    International Centre for Diarrhoeal Disease Research, Bangladesh
    J Clin Microbiol 34:1340-2. 1996
    ..The severity of mixed infections of RV and E. coli was the same as that of infections with RV alone. RV infections mixed with V. cholerae and Shigella species mimicked cholera and shigellosis, respectively...
  34. pmc Distribution of genes for virulence and ecological fitness among diverse Vibrio cholerae population in a cholera endemic area: tracking the evolution of pathogenic strains
    M Hasibur Rahman
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    DNA Cell Biol 27:347-55. 2008
    ..Potential precursors of new pathogenic strains would thus require to assemble a combination of genes for both ecological fitness and virulence to attain epidemiological predominance...
  35. pmc Prevalence of the pandemic genotype of Vibrio parahaemolyticus in Dhaka, Bangladesh, and significance of its distribution across different serotypes
    N A Bhuiyan
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    J Clin Microbiol 40:284-6. 2002
    ..A marker (open reading frame ORF8) for a filamentous phage previously thought to correspond to the pandemic genotype was found to have a poor correlation with the pandemic genotype...
  36. pmc Seasonal epidemics of cholera inversely correlate with the prevalence of environmental cholera phages
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 102:1702-7. 2005
    ..Our data support the conclusion that cholera phages can influence cholera seasonality and may also play a role in emergence of new V. cholerae pandemic serogroups or clones...
  37. ncbi Molecular ecology of toxigenic Vibrio cholerae
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka
    Microbiol Immunol 46:59-66. 2002
    ..cholerae strains with epidemic potential...
  38. pmc Reemergence of epidemic Vibrio cholerae O139, Bangladesh
    Shah M Faruque
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Emerg Infect Dis 9:1116-22. 2003
    ..These findings emphasize the need for continuous monitoring of the new epidemic strains...
  39. pmc Emergence and evolution of Vibrio cholerae O139
    Shah M Faruque
    Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 100:1304-9. 2003
    ..cholerae, not only in the Ganges Delta region of India and Bangladesh, but also in other areas of endemic and epidemic cholera...
  40. pmc Cholera due to altered El Tor strains of Vibrio cholerae O1 in Bangladesh
    G Balakrish Nair
    Laboratory Sciences Division, ICDDR, B Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
    J Clin Microbiol 44:4211-3. 2006
    ..All of the El Tor strains of V. cholerae O1 isolated since 2001 produced CT of the classical biotype, while those isolated before 2001 produced CT of the El Tor biotype...
  41. ncbi Aetiology of diarrhoea in a birth cohort of children aged 0-2 year(s) in rural Mirzapur, Bangladesh
    Khundkar Z Hasan
    Public Health Sciences Division, ICDDR, B Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
    J Health Popul Nutr 24:25-35. 2006
    ..Enterotoxigenic B. fragilis was also identified as a pathogen. Ongoing vaccine efforts focusing on Shigella, rotavirus, and ETEC would be useful...
  42. pmc Quorum-regulated biofilms enhance the development of conditionally viable, environmental Vibrio cholerae
    M Kamruzzaman
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 107:1588-93. 2010
    ..cholerae by blocking quorum-mediated regulatory responses that would break down biofilms and thus interfere with CVEC formation...
  43. ncbi Phenotypic and molecular characteristics of Escherichia coli isolated from aquatic environment of Bangladesh
    Munirul Alam
    Laboratory of Enteric Microbiology, Laboratory Sciences Division, International Center for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh
    Microbiol Immunol 50:359-70. 2006
    ..Finally, it may be concluded that serotype-based pathotyping may be useful for E. coli strains of clinical origin; however, it is not precise enough for reliably identifying environmental strains as diarrheagenic...
  44. ncbi Peru-15, a live attenuated oral cholera vaccine, is safe and immunogenic in Bangladeshi toddlers and infants
    Firdausi Qadri
    ICDDR, B Centre for Health and Population Research, Bangladesh
    Vaccine 25:231-8. 2007
    ..The responses to the reduced dose was lower. These studies demonstrate that Peru-15 at a dose of 2x10(8)cfu is safe and immunogenic in children in Bangladesh...
  45. pmc Diverse CTX phages among toxigenic Vibrio cholerae O1 and O139 strains isolated between 1994 and 2002 in an area where cholera is endemic in Bangladesh
    Suraia Nusrin
    Laboratory Sciences Division, ICDDR, B Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
    J Clin Microbiol 42:5854-6. 2004
    ....
  46. pmc Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in Bangladesh
    Firdausi Qadri
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka
    Infect Immun 73:6577-83. 2005
    ..cholerae O139. Consequently, this assay may be useful in studies of both O139-infected patients and recipients of O139 vaccines...
  47. ncbi Randomized, controlled study of the safety and immunogenicity of Peru-15, a live attenuated oral vaccine candidate for cholera, in adult volunteers in Bangladesh
    Firdausi Qadri
    International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B Centre for Health and Population Research, Dhaka, Bangladesh
    J Infect Dis 192:573-9. 2005
    ..A lower immunological response against cholera toxin B subunit was detected.CONCLUSIONS. The safety and immunogenicity of this Peru-15 vaccine candidate indicates the usefulness of future studies in Bangladesh, where cholera is endemic...
  48. ncbi Pathogenicity islands and phages in Vibrio cholerae evolution
    Shah M Faruque
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Trends Microbiol 11:505-10. 2003
    ..Understanding the evolutionary events that lead to the emergence of pathogenic clones might provide new approaches to the control of cholera and other infectious diseases...
  49. pmc Acquisition of classical CTX prophage from Vibrio cholerae O141 by El Tor strains aided by lytic phages and chitin-induced competence
    S M Nashir Udden
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Proc Natl Acad Sci U S A 105:11951-6. 2008
    ..cholerae. Furthermore, the O141 strains apparently represent an alternative reservoir of the CTX(class) phage genome, because the classical V. cholerae O1 strains are possibly extinct...
  50. pmc Effect of phage on the infectivity of Vibrio cholerae and emergence of genetic variants
    M Shamim Hasan Zahid
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Infect Immun 76:5266-73. 2008
    ..Furthermore, the dominance of phage-resistant variants due to the bactericidal selective mechanism occurs rarely in natural settings, and the emerging variants are thus unable to sustain the ongoing epidemic...
  51. ncbi Immune response of Bangladeshi children with acute diarrhea who subsequently have persistent diarrhea
    T Azim
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka
    J Pediatr Gastroenterol Nutr 31:528-35. 2000
    ....
  52. ncbi The efficacy of bismuth subsalicylate in the treatment of acute diarrhoea and the prevention of persistent diarrhoea
    H R Chowdhury
    Public Health Sciences Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Acta Paediatr 90:605-10. 2001
    ..Conclusion: Treatment with BSS had a modest therapeutic effect on acute diarrhoea, as has been previously demonstrated, but with no suggestion of a therapeutic effect on the prevention of persistent diarrhoea in this group of patients...
  53. pmc The cyclic AMP (cAMP)-cAMP receptor protein signaling system mediates resistance of Vibrio cholerae O1 strains to multiple environmental bacteriophages
    M Shamim Hasan Zahid
    Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
    Appl Environ Microbiol 76:4233-40. 2010
    ..cholerae O1 strains to survive predation by multiple environmental phages. Furthermore, the cyaA or crp mutant strains may be used as suitable indicators in monitoring cholera phages in the water...
  54. pmc An inducible lambdoid prophage encoding cytolethal distending toxin (Cdt-I) and a type III effector protein in enteropathogenic Escherichia coli
    Masahiro Asakura
    Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Gakuen cho, Naka ku, Sakai, Osaka 599 8531, Japan
    Proc Natl Acad Sci U S A 104:14483-8. 2007
    ..Our results suggest that CDT-1Phi is the latest member of a growing family of lambdoid phages encoding bacterial cyclomodulins and that the phage may have a role in horizontal transfer of these virulence genes...
  55. pmc Cloning and characterization of genes encoding homologues of the B subunit of cholera toxin and the Escherichia coli heat-labile enterotoxin from clinical isolates of Citrobacter freundii and E. coli
    Tadahiro Karasawa
    Department of Bacteriology, Graduate School of Medical Science, Kanazawa University, 13 1 Takara machi, Japan
    Infect Immun 70:7153-5. 2002
    ..The results of the present study may provide important clues to the origin and evolution of immunologically related factors sharing a common enterotoxin-like A and B subunit structures...
  56. ncbi A 4-year study of the epidemiology of Vibrio cholerae in four rural areas of Bangladesh
    R Bradley Sack
    Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    J Infect Dis 187:96-101. 2003
    ..These data will be correlated with environmental factors, to develop a model for prediction of cholera outbreaks...
  57. pmc Modeling the role of bacteriophage in the control of cholera outbreaks
    Mark A Jensen
    Department of Biology, Emory University, Atlanta, GA 30332, USA
    Proc Natl Acad Sci U S A 103:4652-7. 2006
    ..cholerae. Our theoretical results make a number of empirically testable predictions...
  58. ncbi Molecular characterisation of rough strains of Vibrio cholerae isolated from diarrhoeal cases in India and their comparison to smooth strains
    Keya De
    Division of Microbiology, National Institute of Cholera and Enteric Diseases, P33 CIT Road, Scheme XM, Kolkata 700 010, India
    FEMS Microbiol Lett 232:23-30. 2004
    ..Strains exhibiting the rough phenotype were more amenable to the uptake of CTXphi, which led us to consider that the rough phenotype could play a role in the generation of genetic diversity among V. cholerae strains...
  59. pmc Transcriptional profiling of Vibrio cholerae recovered directly from patient specimens during early and late stages of human infection
    Regina C LaRocque
    Division of Infectious Diseases, Gray Jackson 504, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Infect Immun 73:4488-93. 2005
    ..These findings provide a more detailed assessment of the transcriptome of V. cholerae in the human host than previous studies of organisms in stool alone and have implications for cholera control and the design of improved vaccines...
  60. pmc Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system
    Michelle Dziejman
    Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 102:3465-70. 2005
    ..We hypothesize that the TTSS present in some pathogenic strains of non-O1, non-O139 V. cholerae may be involved in the virulence and environmental fitness of these strains...
  61. pmc Seasonal cholera from multiple small outbreaks, rural Bangladesh
    O Colin Stine
    University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Emerg Infect Dis 14:831-3. 2008
    ..The observed minimal overlap in VNTR patterns between the 2 communities was consistent with sequential, small outbreaks from local sources...
  62. ncbi Molecular epidemiological studies of Vibrio cholerae in Bengal region
    Sumio Shinoda
    Faculty of Science, Okayama University of Science, Ridai cho, Okayama 700 0005, Japan
    Biocontrol Sci 13:1-8. 2008
    ....
  63. pmc Cholera stool bacteria repress chemotaxis to increase infectivity
    Susan M Butler
    Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111, USA
    Mol Microbiol 60:417-26. 2006
    ..Through mutational analyses, such a state is known to enhance the infectivity of V. cholerae. This is the first report of a pathogen altering its chemotactic state in response to human infection in order to enhance its transmission...