P Aaby

Summary

Affiliation: Bandim Health Project

Publications

  1. pmc Determinants of vitamin a deficiency in children between 6 months and 2 years of age in Guinea-Bissau
    Niels Danneskiold-Samsøe
    Research Center for Vitamins and Vaccines, Bandim Health Project, Statens Serum Institut, Orestads Boulevard, Copenhagen S 2300, Denmark
    BMC Public Health 13:172. 2013
  2. pmc A prospective study of twinning and perinatal mortality in urban Guinea-Bissau
    Morten Bjerregaard-Andersen
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004, Bissau Codex, Guinea Bissau
    BMC Pregnancy Childbirth 12:140. 2012
  3. pmc Early diphtheria-tetanus-pertussis vaccination associated with higher female mortality and no difference in male mortality in a cohort of low birthweight children: an observational study within a randomised trial
    Peter Aaby
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Arch Dis Child 97:685-91. 2012
  4. pmc HTLV-1 in rural Guinea-Bissau: prevalence, incidence and a continued association with HIV between 1990 and 2007
    Carla van Tienen
    Medical Research Council, Fajara, The Gambia
    Retrovirology 7:50. 2010
  5. pmc Mortality associated with HIV-1, HIV-2, and HTLV-I single and dual infections in a middle-aged and older population in Guinea-Bissau
    Birgitta Holmgren
    Bandim Health Project, Bissau, INDEPTH Network, Guinea Bissau
    Retrovirology 4:85. 2007
  6. pmc Undetectable plasma viral load predicts normal survival in HIV-2-infected people in a West African village
    Maarten F Schim van der Loeff
    MRC Laboratories Fajara, PO Box 273, Banjul, The Gambia
    Retrovirology 7:46. 2010
  7. pmc The impact of different doses of vitamin A supplementation on male and female mortality. A randomised trial from Guinea-Bissau
    Dorthe Yakymenko
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    BMC Pediatr 11:77. 2011
  8. pmc Tuberculosis burden in an urban population: a cross sectional tuberculosis survey from Guinea Bissau
    Morten Bjerregaard-Andersen
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004 Bissau Codex, Guinea Bissau
    BMC Infect Dis 10:96. 2010
  9. ncbi request reprint The sequence of vaccinations and increased female mortality after high-titre measles vaccine: trials from rural Sudan and Kinshasa
    Peter Aaby
    Bandim Health Project, Danish Epidemiology Science Centre Statens Serum Institut, Apartado 861, Bissau, Guinea Bissau
    Vaccine 24:2764-71. 2006
  10. doi request reprint Sex differences in the effect of vaccines on the risk of hospitalization due to measles in Guinea-bissau
    Peter Aaby
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Pediatr Infect Dis J 29:324-8. 2010

Collaborators

Detail Information

Publications117 found, 100 shown here

  1. pmc Determinants of vitamin a deficiency in children between 6 months and 2 years of age in Guinea-Bissau
    Niels Danneskiold-Samsøe
    Research Center for Vitamins and Vaccines, Bandim Health Project, Statens Serum Institut, Orestads Boulevard, Copenhagen S 2300, Denmark
    BMC Public Health 13:172. 2013
    ..To date, no national survey has been conducted. We assessed vitamin A status among children in rural Guinea-Bissau to assess status and identify risk factors for VAD...
  2. pmc A prospective study of twinning and perinatal mortality in urban Guinea-Bissau
    Morten Bjerregaard-Andersen
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004, Bissau Codex, Guinea Bissau
    BMC Pregnancy Childbirth 12:140. 2012
    ..Despite twinning being common in Africa, few prospective twin studies have been conducted. We studied twinning rate, perinatal mortality and the clinical characteristics of newborn twins in urban Guinea-Bissau...
  3. pmc Early diphtheria-tetanus-pertussis vaccination associated with higher female mortality and no difference in male mortality in a cohort of low birthweight children: an observational study within a randomised trial
    Peter Aaby
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Arch Dis Child 97:685-91. 2012
    ..The authors examined the effect of DTP in a cohort of low birthweight (LBW) infants...
  4. pmc HTLV-1 in rural Guinea-Bissau: prevalence, incidence and a continued association with HIV between 1990 and 2007
    Carla van Tienen
    Medical Research Council, Fajara, The Gambia
    Retrovirology 7:50. 2010
    ..In the current study, data from three cross-sectional community surveys performed in 1990, 1997 and 2007, were used to assess changes in HTLV-1 prevalence, incidence and its associations with HIV-1 and HIV-2 and potential risk factors...
  5. pmc Mortality associated with HIV-1, HIV-2, and HTLV-I single and dual infections in a middle-aged and older population in Guinea-Bissau
    Birgitta Holmgren
    Bandim Health Project, Bissau, INDEPTH Network, Guinea Bissau
    Retrovirology 4:85. 2007
    ..The present study compares mortality associated with HIV-1, HIV-2, and HTLV-I single and dual infections in individuals over 35 years of age within an urban community-based cohort in Guinea-Bissau...
  6. pmc Undetectable plasma viral load predicts normal survival in HIV-2-infected people in a West African village
    Maarten F Schim van der Loeff
    MRC Laboratories Fajara, PO Box 273, Banjul, The Gambia
    Retrovirology 7:46. 2010
    ..There have been no previous studies of the long-term survival and temporal changes in plasma viral load among HIV-2 infected subjects...
  7. pmc The impact of different doses of vitamin A supplementation on male and female mortality. A randomised trial from Guinea-Bissau
    Dorthe Yakymenko
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    BMC Pediatr 11:77. 2011
    ..We aimed to test these observations...
  8. pmc Tuberculosis burden in an urban population: a cross sectional tuberculosis survey from Guinea Bissau
    Morten Bjerregaard-Andersen
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004 Bissau Codex, Guinea Bissau
    BMC Infect Dis 10:96. 2010
    ..We conducted a cross sectional survey for pulmonary TB and TB symptoms in Bissau, Guinea-Bissau, in an urban cohort with known HIV prevalence. TB surveillance in the area is routinely based on passive case finding...
  9. ncbi request reprint The sequence of vaccinations and increased female mortality after high-titre measles vaccine: trials from rural Sudan and Kinshasa
    Peter Aaby
    Bandim Health Project, Danish Epidemiology Science Centre Statens Serum Institut, Apartado 861, Bissau, Guinea Bissau
    Vaccine 24:2764-71. 2006
    ....
  10. doi request reprint Sex differences in the effect of vaccines on the risk of hospitalization due to measles in Guinea-bissau
    Peter Aaby
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Pediatr Infect Dis J 29:324-8. 2010
    ....
  11. ncbi request reprint Vaccinia scars associated with better survival for adults. An observational study from Guinea-Bissau
    Peter Aaby
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau, Denmark
    Vaccine 24:5718-25. 2006
    ..Live vaccines including BCG and measles may have non-targeted beneficial effects on childhood survival in areas with high mortality. The authors therefore undertook a survey of vaccinia scars to evaluate subsequent mortality...
  12. doi request reprint Randomized trial of BCG vaccination at birth to low-birth-weight children: beneficial nonspecific effects in the neonatal period?
    Peter Aaby
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    J Infect Dis 204:245-52. 2011
    ..Low-birth-weight (LBW) children are not given BCG at birth in Guinea-Bissau; we conducted a randomized trial of BCG at birth (early BCG) vs delayed BCG...
  13. ncbi request reprint Non-specific and sex-differential effects of routine vaccines: what evidence is needed to take these effects into consideration in low-income countries?
    Peter Aaby
    Bandim Health Project, Bissau, Guinea Bissau, Denmark
    Hum Vaccin 7:120-4. 2011
    ..It would usually be considered unethical to test currently recommended vaccines as part of a trial withholding these vaccines from some children (6)...
  14. ncbi request reprint Age-specific changes in the female-male mortality ratio related to the pattern of vaccinations: an observational study from rural Gambia
    Peter Aaby
    Bandim Health Project, Apartado 861, Bissau, Guinea Bissau
    Vaccine 24:4701-8. 2006
    ..We used data from The Gambia to examine whether similar tendencies could be found in a different setting...
  15. ncbi request reprint Sex differential effects of routine immunizations and childhood survival in rural Malawi
    Peter Aaby
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Pediatr Infect Dis J 25:721-7. 2006
    ..Recent studies from West Africa suggest that routine vaccinations may have sex differential nontargeted effects. To answer whether these patterns are found elsewhere, we reanalyzed data about vaccinations and mortality in a Malawian cohort...
  16. ncbi request reprint International health at home: learning from low-income countries--secondary publication
    Peter Aaby
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Dan Med Bull 54:147-9. 2007
    ..Examples are given of how observations in Guinea-Bissau have led to reinterpretation of the decline in measles mortality in the industrialised countries, the polio model and the impact of stopping vaccinations after eradication...
  17. ncbi request reprint Increased female-male mortality ratio associated with inactivated polio and diphtheria-tetanus-pertussis vaccines: Observations from vaccination trials in Guinea-Bissau
    Peter Aaby
    Projecto de Saude de Bandim, INDEPTH Network, Bissau, Guinea Bissau
    Pediatr Infect Dis J 26:247-52. 2007
    ..The 2-fold increase in female mortality after high-titer measles vaccine may have occurred because many children received diphtheria-tetanus-pertussis (DTP) vaccine or inactivated polio vaccine (IPV) after high-titer measles vaccine...
  18. ncbi request reprint Is susceptibility to severe infection in low-income countries inherited or acquired?
    P Aaby
    Bandim Health Project, Statens Serum Institut, Bissau, Guinea Bissau
    J Intern Med 261:112-22. 2007
    ..There are many acquired factors, which affect susceptibility to infection in ways which have not been explored by medical science. They may have a major impact on child survival in low-income countries...
  19. ncbi request reprint DTP vaccination and child survival in observational studies with incomplete vaccination data
    Peter Aaby
    Bandim Health Project, Danish Epidemiology Science Centre and Statens Serum Institut, Bissau, Guinea Bissau, Denmark
    Trop Med Int Health 12:15-24. 2007
    ..None of these studies had complete information on DTP vaccinations from both survivors and children who died. We reviewed the data analysis methodology to assess whether methodological differences could explain the divergent results...
  20. pmc Non-specific effects of standard measles vaccine at 4.5 and 9 months of age on childhood mortality: randomised controlled trial
    Peter Aaby
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    BMJ 341:c6495. 2010
    ..5 months and 3 years of age for children given two standard doses of Edmonston-Zagreb measles vaccines at 4.5 and 9 months of age compared with those given one dose of measles vaccine at 9 months of age (current policy)...
  21. ncbi request reprint DTP with or after measles vaccination is associated with increased in-hospital mortality in Guinea-Bissau
    Peter Aaby
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau
    Vaccine 25:1265-9. 2007
    ..The sequence is not always respected. We examined in-hospital mortality of children having received DTP with or after measles vaccine...
  22. ncbi request reprint Measles antibody responses after early two dose trials in Guinea-Bissau with Edmonston-Zagreb and Schwarz standard-titre measles vaccine: better antibody increase from booster dose of the Edmonston-Zagreb vaccine
    M L Garly
    Projecto de Saude de Bandim, Apartado 861, 1004, Bissau Codex, Guinea Bissau
    Vaccine 19:1951-9. 2001
    ..The EZ vaccine was less sensitive to maternal antibodies, and able to increase the antibody response by revaccination, while the second SW vaccine resulted in an unchanged or lower antibody response...
  23. pmc Non-specific beneficial effect of measles immunisation: analysis of mortality studies from developing countries
    P Aaby
    Epidemiology Research Unit, Danish Epidemiology Science Centre, Statens Seruminstitut, Copenhagen
    BMJ 311:481-5. 1995
    ..CONCLUSION--These observations suggest that standard titre measles vaccine may confer a beneficial effect which is unrelated to the specific protection against measles disease...
  24. ncbi request reprint Cryptosporidium infection in infancy as a cause of malnutrition: a community study from Guinea-Bissau, west Africa
    K Mølbak
    Epidemiology Research Unit, Danish Epidemiology Science Centre, Copenhagen, Denmark
    Am J Clin Nutr 65:149-52. 1997
    ..02). Although it has been suggested that the effect of infections on nutrition is usually transient because of catch-up growth, the present study suggests that cryptosporidiosis in infancy has a permanent effect on growth...
  25. ncbi request reprint Community-based randomized controlled trial of reduced osmolarity oral rehydration solution in acute childhood diarrhea
    P Valentiner-Branth
    Bandim Health Project, Guinea Bissau
    Pediatr Infect Dis J 18:789-95. 1999
    ..We conducted a community-based study comparing the efficacy of reduced osmolarity ORS (224 mmol/l) with standard ORS (311 mmol/l) in acute childhood diarrhea in a West African community...
  26. ncbi request reprint Community-based controlled trial of dietary management of children with persistent diarrhea: sustained beneficial effect on ponderal and linear growth
    P Valentiner-Branth
    Projecto de Saude de Bandim, Bissau, Guinea Bissau
    Am J Clin Nutr 73:968-74. 2001
    ..Uncontrolled hospital-based studies in developing countries have reported promising results of dietary rehabilitation of children with persistent diarrhea...
  27. ncbi request reprint Dual infections with HIV-1, HIV-2 and HTLV-I are more common in older women than in men in Guinea-Bissau
    Birgitta Holmgren
    Bandim Health Project, Danish Epidemiology Science Centre, Bissau, Guinea Bissau
    AIDS 17:241-53. 2003
    ..To investigate the association between the three human retroviruses, HIV-1, HIV-2 and HTLV-I...
  28. doi request reprint Mid-upper-arm-circumference and mid-upper-arm circumference z-score: the best predictor of mortality?
    J Rasmussen
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    Eur J Clin Nutr 66:998-1003. 2012
    ..We evaluated whether MUAC or MUAC z-score had the best ability to identify children with high short-term mortality risk in Guinea-Bissau...
  29. ncbi request reprint No adverse events after simultaneous administration of 50 000 IU vitamin A and Bacille Calmette-Guerin vaccination to normal-birth-weight newborns in Guinea-Bissau
    J E Nante
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Eur J Clin Nutr 62:842-8. 2008
    ....
  30. ncbi request reprint HTLV-1 infection in a population-based cohort of older persons in Guinea-Bissau, West Africa: risk factors and impact on survival
    M Melbye
    Projecto de Saude de Bandim, Bissau, Guinea Bissau
    Int J Cancer 76:293-8. 1998
    ..Whereas sexual behaviors are clearly important for HTLV-1 spread in women, non-sexual risk factors were the only ones of potential importance in men. HTLV-1 had no impact on survival in this older population...
  31. ncbi request reprint Survival of previously measles-vaccinated and measles-unvaccinated children in an emergency situation: an unplanned study
    Peter Aaby
    Bandim Health Project, Bissau, Guinea Bissau
    Pediatr Infect Dis J 22:798-805. 2003
    ..However, these observations have not been based on randomized trials...
  32. ncbi request reprint Divergent female-male mortality ratios associated with different routine vaccinations among female-male twin pairs
    Peter Aaby
    Bandim Health Project, Apartado 861, Bissau, Guinea Bissau
    Int J Epidemiol 33:367-73. 2004
    ..As background information, we examined sex- and age-specific mortality patterns in the pre-vaccination era. Subjects In all, 626 female-male twin pairs identified between 1978 and 2000...
  33. ncbi request reprint Cancer risk in a cohort of polio patients
    N M Nielsen
    Department of Epidemiology Research, Danish Epidemiology Science Center, Statens Serum Institut, Copenhagen, Denmark
    Int J Cancer 92:605-8. 2001
    ..09 [0.72 to 1.60]). Women diagnosed with poliomyelitis, in particular paralytic polio, may be at increased risk of breast cancer. There was no association between malignancies of the CNS and poliomyelitis...
  34. ncbi request reprint Thymus size and head circumference at birth and the development of allergic diseases
    C S Benn
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Coenhagen, Denmark
    Clin Exp Allergy 31:1862-6. 2001
    ....
  35. doi request reprint Diphtheria-tetanus-pertussis vaccine administered simultaneously with measles vaccine is associated with increased morbidity and poor growth in girls. A randomised trial from Guinea-Bissau
    J Agergaard
    Bandim Health Project, INDEPTH Network, Apartado 861, 1004 Bissau Codex, Guinea Bissau
    Vaccine 29:487-500. 2011
    ..We hypothesised that the MV+OPV group would experience less morbidity and grow better. Due to previous observations of sex differences in the non-specific effects of vaccinations, we analysed all data stratified by sex...
  36. ncbi request reprint Bacillus Calmette-Guérin vaccination and infant mortality
    Adam Roth
    Statens Serum Institut, Bandim Health Project, Artillerivej 5, 2300 Copenhagen S, Denmark
    Expert Rev Vaccines 5:277-93. 2006
    ..A nonspecific, gender-differential effect of BCG on general infant mortality may have large implications for tuberculosis vaccine research and routine vaccination policy...
  37. ncbi request reprint Routine vaccinations associated with divergent effects on female and male mortality at the paediatric ward in Bissau, Guinea-Bissau
    Jens Erik Veirum
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau
    Vaccine 23:1197-204. 2005
    ..Understanding the divergent non-specific effects of common vaccines may contribute to better child survival in developing countries...
  38. ncbi request reprint Differences in female-male mortality after high-titre measles vaccine and association with subsequent vaccination with diphtheria-tetanus-pertussis and inactivated poliovirus: reanalysis of West African studies
    Peter Aaby
    Projecto de Saude de Bandim, Danish Epidemiology Science Centre, Apartado 861, Bissau, Guinea Bissau
    Lancet 361:2183-8. 2003
    ..We aimed to assess whether DTP or inactivated poliovirus (IPV) administered after HTMV was associated with increased female-male mortality ratio...
  39. pmc The effect of vitamin A supplementation administered with missing vaccines during national immunization days in Guinea-Bissau
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Int J Epidemiol 38:304-11. 2009
    ..We assessed the effect of VAS administered with different vaccines during national immunization days (NIDs)...
  40. pmc Sex-differential effect on infant mortality of oral polio vaccine administered with BCG at birth in Guinea-Bissau. A natural experiment
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    PLoS ONE 3:e4056. 2008
    ..During a trial of vitamin A supplementation (VAS) at birth in Guinea-Bissau, OPV was not available during several periods. We took advantage of this "natural experiment" to test the effect on mortality of receiving OPV at birth...
  41. ncbi request reprint Effect of high-dose vitamin A supplementation on the immune response to Bacille Calmette-Guerin vaccine
    Birgitte R Diness
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Am J Clin Nutr 86:1152-9. 2007
    ..Bacille Calmette-Guérin (BCG) vaccine is given at birth in tuberculosis-endemic countries. Previous studies suggest that VAS may influence the immune response to vaccines...
  42. doi request reprint Does vitamin A supplementation interact with routine vaccinations? An analysis of the Ghana Vitamin A Supplementation Trial
    Christine S Benn
    Statens Serum Institut, Copenhagen, Denmark
    Am J Clin Nutr 90:629-39. 2009
    ..However, it is unknown whether the effect of VAS is independent of vaccinations. One of the original VAS trials from Ghana had collected vaccination information...
  43. doi request reprint The effect of high-dose vitamin A supplementation given with bacille Calmette-Guérin vaccine at birth on infant rotavirus infection and diarrhea: a randomized prospective study from Guinea-Bissau
    Birgitte Rode Diness
    Bandim Health Project, INDEPTH Network, Guinea Bissau
    J Infect Dis 202:S243-51. 2010
    ..Prophylactic vitamin A supplementation (VAS) reduces mortality and may reduce morbidity associated with diarrhea in children >6 months of age. Rotavirus is the most common cause of acute dehydrating diarrhea among children worldwide...
  44. ncbi request reprint BCG vaccination among West African infants is associated with less anergy to tuberculin and diphtheria-tetanus antigens
    M L Garly
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau
    Vaccine 20:468-74. 2001
    ..BCG vaccination and a positive tuberculin reaction were associated with a lower prevalence of anergy to both tuberculin and diphtheria-tetanus. Thus, BCG vaccination may contribute to better cell-mediated immune responses among infants...
  45. ncbi request reprint No strong long-term effect of vitamin A supplementation in infancy on CD4 and CD8 T-cell subsets. A community study from Guinea-Bissau, West Africa
    C S Benn
    Department of Epidemiology Research, Statens Serum Institut, 5 Artillerivej, 2300 Copenhagen S, Denmark
    Ann Trop Paediatr 20:259-64. 2000
    ..Based on these observations, vitamin A supplementation does not seem to have a strong long-term effect on CD4 and CD8 T-cell subsets in infants without clinical vitamin A deficiency...
  46. ncbi request reprint Knowing a medical doctor is associated with reduced mortality among sick children consulting a paediatric ward in Guinea-Bissau, West Africa
    M Sodemann
    Projecto de Saude Bandim, Bissau, Guinea Bissau
    Trop Med Int Health 11:1868-77. 2006
    ..To examine equity in access to public health services in Guinea-Bissau...
  47. ncbi request reprint Seven years' experience with Cryptosporidium parvum in Guinea-Bissau, West Africa
    M Perch
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Denmark
    Ann Trop Paediatr 21:313-8. 2001
    ..By contrast, no seasonality was found for the enteric parasites Giardia lamblia or Entamoeba histolytica. We conclude that Cryptosporidium parvum is an important pathogen in children with diarrhoea...
  48. doi request reprint Should infant girls receive micronutrient supplements?
    Christine Stabell Benn
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Int J Epidemiol 38:586-90. 2009
    ..Recent zinc/folic acid (FA) and iron supplementation trials did not find any beneficial effects on mortality. We reviewed the studies for evidence of a negative interaction between zinc/folic acid/iron and DTP vaccination in girls...
  49. ncbi request reprint The survival benefit of measles immunization may not be explained entirely by the prevention of measles disease: a community study from rural Bangladesh
    Peter Aaby
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Seruminstitut, Copenhagen, Denmark
    Int J Epidemiol 32:106-16. 2003
    ..To examine whether the reduction in childhood mortality after immunization can be explained by the prevention of measles and its long-term effects...
  50. ncbi request reprint Low birth weight infants and Calmette-Guérin bacillus vaccination at birth: community study from Guinea-Bissau
    Adam Roth
    Bandim Health Project, Bissau, Guinea Bissau
    Pediatr Infect Dis J 23:544-50. 2004
    ..Recent studies have suggested that BCG may have a nonspecific beneficial effect on infant mortality. We evaluated the consequences of not vaccinating LBW children at birth in Guinea-Bissau...
  51. ncbi request reprint Increased prevalence of HTLV-1 among HIV-2-infected women but not HIV-2-infected men in rural Guinea-Bissau
    Birgitta Holmgren
    Bandim Health Project, Danish Epidemiology Science Centre, Bissau, Guinea Bissau
    J Acquir Immune Defic Syndr 30:342-50. 2002
    ..To assess the prevalence of HTLV infection and its association with HIV and other potential risk factors...
  52. pmc Protective efficacy of standard Edmonston-Zagreb measles vaccination in infants aged 4.5 months: interim analysis of a randomised clinical trial
    Cesário L Martins
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    BMJ 337:a661. 2008
    ..To examine the protective efficacy of measles vaccination in infants in a low income country before 9 months of age...
  53. ncbi request reprint Routine vaccinations and child survival in a war situation with high mortality: effect of gender
    Peter Aaby
    Bandim Health Project, Apartado 861, Bissau Guinea Bissau and Danish Epidemiology Science Centre, Artillerivej 5, 2300 Copenhagen S, Denmark
    Vaccine 21:15-20. 2002
    ..Non-specific effects of vaccination should be assessed separately for boys and girls. Taking these effects into consideration may have implications for child mortality patterns in developing countries...
  54. ncbi request reprint Survival bias in observational studies of the impact of routine immunizations on childhood survival
    Henrik Jensen
    Bandim Health Project, Danish Epidemiology Science Centre and Statens Serum Institut, Copenhagen, Denmark
    Trop Med Int Health 12:5-14. 2007
    ..We examined whether this could be because of methodological differences...
  55. pmc Nutritional status and mortality of refugee and resident children in a non-camp setting during conflict: follow up study in Guinea-Bissau
    P Aaby
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, 2300 Copenhagen S, Denmark
    BMJ 319:878-81. 1999
    ..To study the effects on children of humanitarian aid agencies restricting help to refugee families (internally displaced people)...
  56. ncbi request reprint Survival among motherless children in rural and urban areas in Guinea-Bissau
    T N Masmas
    Projecto de, Saúde de Bandim, Bissau, Guinea Bissau, Denmark
    Acta Paediatr 93:99-105. 2004
    ..However, few studies describe the survival patterns of these children. The aim of this study was to investigate the mortality of motherless children in urban and rural areas of Guinea-Bissau...
  57. ncbi request reprint Intensive exposure as a risk factor for severe polio: a study of multiple family cases
    N M Nielsen
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen
    Scand J Infect Dis 33:301-5. 2001
    ..Furthermore, intensive exposure from being infected in the household increased severity. These observations therefore suggest that intensity of exposure and dose of infection are important factors in the severity of poliomyelitis...
  58. ncbi request reprint Termination of breastfeeding after 12 months of age due to a new pregnancy and other causes is associated with increased mortality in Guinea-Bissau
    M S Jakobsen
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau
    Int J Epidemiol 32:92-6. 2003
    ..As part of an assessment of breastfeeding and child health in Guinea-Bissau, we investigated the impact of mother's reason for weaning on subsequent child mortality...
  59. ncbi request reprint Beneficial non-targeted effects of BCG--ethical implications for the coming introduction of new TB vaccines
    A E Roth
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    Tuberculosis (Edinb) 86:397-403. 2006
    ....
  60. ncbi request reprint [Gender differences in response to preventive health care interventions. Do we have to treat girls and boys differently to treat them equally?]
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, København
    Ugeskr Laeger 168:3045-6. 2006
    ..If these observations reflect a general pattern, it may be that, in order to be treated equally, boys and girls should be treated differently...
  61. ncbi request reprint Increased mortality in the year following discharge from a paediatric ward in Bissau, Guinea-Bissau
    Jens Erik Veirum
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau
    Acta Paediatr 96:1832-8. 2007
    ..A better understanding of the determinants of posthospital mortality could help improve discharge policies and interventions with implications for overall childhood mortality...
  62. pmc Effect of 50,000 IU vitamin A given with BCG vaccine on mortality in infants in Guinea-Bissau: randomised placebo controlled trial
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
    BMJ 336:1416-20. 2008
    ..To investigate the effect of high dose vitamin A supplementation given with BCG vaccine at birth in an African setting with high infant mortality...
  63. ncbi request reprint High-titer measles vaccination before 9 months of age and increased female mortality: do we have an explanation?
    Peter Aaby
    Projecto do Saúde de Bandim, Danish Epidemiology Science Centre, Bissau, Guinea Bissau
    Semin Pediatr Infect Dis 14:220-32. 2003
    ....
  64. ncbi request reprint The introduction of diphtheria-tetanus-pertussis vaccine and child mortality in rural Guinea-Bissau: an observational study
    Peter Aaby
    Bandim Health Project, Apartado 861, Bissau, Guinea Bissau
    Int J Epidemiol 33:374-80. 2004
    ..We therefore examined mortality when DTP was first introduced in rural areas of Guinea-Bissau in 1984-1987. Setting Twenty villages in four regions have been followed with bi-annual examinations since 1979...
  65. ncbi request reprint Tuberculosis in Bissau: incidence and risk factors in an urban community in sub-Saharan Africa
    Per Gustafson
    Projecto de Saude de Bandim, Danish Epidemiology Science Centre, Bissau, Guinea Bissau
    Int J Epidemiol 33:163-72. 2004
    ..Despite the long history of tuberculosis (TB) research, population-based studies from developing countries are rare...
  66. ncbi request reprint Community cohort study of rotavirus and other enteropathogens: are routine vaccinations associated with sex-differential incidence rates?
    Amabelia Rodrigues
    Bandim Health Project, Danish Epidemiology Science Centre, Statens Serum Institut, Apartado 861, Bissau, Guinea Bissau
    Vaccine 24:4737-46. 2006
    ..We examined whether immunisation status was associated with infection with rotavirus and other enteropathogens...
  67. doi request reprint Adherence to isoniazid preventive therapy in children exposed to tuberculosis: a prospective study from Guinea-Bissau
    V F Gomes
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Int J Tuberc Lung Dis 15:1637-43. 2011
    ..To assess adherence to isoniazid preventive therapy (IPT) in children exposed to adult pulmonary tuberculosis (TB) at home...
  68. ncbi request reprint Intensity of exposure and severity of whooping cough
    N M Nielsen
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    J Infect 43:177-81. 2001
    ..To study the association between intensity of exposure and mortality due to pertussis...
  69. ncbi request reprint A household study of chickenpox in Guinea-Bissau: intensity of exposure is a determinant of severity
    A Poulsen
    Projecto de Saude de Bandim, Guinea Bissau, Denmark
    J Infect 45:237-42. 2002
    ..To determinate the relative importance of state of nutrition and intensity of exposure for clinical severity of chickenpox in a developing country...
  70. ncbi request reprint Persisting high hospital and community childhood mortality in an urban setting in Guinea-Bissau
    Jens Erik Veirum
    Projecto de Saude de Bandim, Apartado 861, Bissau, Guinea Bissau
    Acta Paediatr 96:1526-30. 2007
    ..To describe paediatric hospitalization in a West African capital in relation to overall childhood mortality in the community and to evaluate the potential impact of improved management at the hospital...
  71. ncbi request reprint Effect of vitamin A supplementation with BCG vaccine at birth on vitamin A status at 6 wk and 4 mo of age
    Ane B Fisker
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau
    Am J Clin Nutr 86:1032-9. 2007
    ..The effect of vitamin A supplementation (VAS) at birth on subsequent vitamin A status has not been studied...
  72. pmc Effect of revaccination with BCG in early childhood on mortality: randomised trial in Guinea-Bissau
    Adam Edvin Roth
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    BMJ 340:c671. 2010
    ..To determine whether BCG revaccination at 19 months of age reduces overall child mortality...
  73. doi request reprint Urine suPAR levels compared with plasma suPAR levels as predictors of post-consultation mortality risk among individuals assumed to be TB-negative: a prospective cohort study
    Paulo Rabna
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau Codex, Guinea Bissau
    Inflammation 33:374-80. 2010
    ..75. For HIV-negative individuals, little or no prognostic effect was observed. However, in both HIV positives and negatives, the predictive effect of U-suPAR was found to be inferior to that of P-suPAR...
  74. pmc Vitamin A supplementation and BCG vaccination at birth in low birthweight neonates: two by two factorial randomised controlled trial
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, Copenhagen, Denmark
    BMJ 340:c1101. 2010
    ..To investigate the effect of vitamin A supplementation and BCG vaccination at birth in low birthweight neonates...
  75. doi request reprint High mortality risk among individuals assumed to be TB-negative can be predicted using a simple test
    Paulo Rabna
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau, West Africa
    Trop Med Int Health 14:986-94. 2009
    ..To determine mortality among assumed TB negative (aTBneg) individuals in Guinea-Bissau and to investigate whether plasma levels of soluble urokinase receptor (suPAR) can be used to determine post-consultation mortality risk...
  76. doi request reprint Girls may have lower levels of maternal measles antibodies and higher risk of subclinical measles infection before the age of measles vaccination
    Cesario Martins
    Bandim Health Project, INDEPTH Network, Apartado 861, Bissau, Guinea Bissau
    Vaccine 27:5220-5. 2009
    ..Previous studies have suggested that girls may have lower maternal measles antibody levels than boys. Girls might therefore be more likely to contract measles infection before the normal age of measles vaccination at 9 months of age...
  77. doi request reprint Decline in human T-cell lymphotropic virus-1 prevalence in urban areas of Bissau, Guinea-Bissau: exploring the association with HIV infections
    Zacarias J da Silva
    Bandim Health Project, Apt 861, Bissau Codex 1004, Guinea Bissau
    AIDS 23:637-9. 2009
    ..The prevalence of HTLV-1 declined significantly from 3.5% in 1996 to 2.3% in 2006. The incidence between 1996 and 2006 was only 0.9/1000 person-years and tended to be higher for women than for men...
  78. doi request reprint Changes in prevalence and incidence of HIV-1, HIV-2 and dual infections in urban areas of Bissau, Guinea-Bissau: is HIV-2 disappearing?
    Zacarias J da Silva
    Bandim Health Project, INDEPTH Network, Bissau, Sweden
    AIDS 22:1195-202. 2008
    ..To assess the changes in HIV prevalence and incidence between 1996 and 2006 in urban areas of Bissau...
  79. doi request reprint Changing pattern of malaria in Bissau, Guinea Bissau
    Amabelia Rodrigues
    Projecto de Saude de Bandim, INDEPTH Network, Bissau, Guine Bissau
    Trop Med Int Health 13:410-7. 2008
    ..To describe the epidemiology of malaria in Guinea-Bissau, in view of the fact that more funds are available now for malaria control in the country...
  80. ncbi request reprint Sex-differential responses to preventive health interventions. Maybe we treat boys and girls differently when we treat them equally?--Secondary publication
    Christine Stabell Benn
    Bandim Health Project, Statens Serum Institut, 2300 Copenhagen S, Denmark
    Dan Med Bull 54:153-4. 2007
    ....
  81. ncbi request reprint Community cohort study of Cryptosporidium parvum infections: sex-differential incidences associated with BCG and diphtheria-tetanus-pertussis vaccinations
    Palle Valentiner-Branth
    Bandim Health Project, Danish Epidemiology Science Centre, Statens Serum Institut, Apartado 861, Bissau, Guinea Bissau, Denmark
    Vaccine 25:2733-41. 2007
    ..Using an existing data set, we examined whether vaccinations were associated with gender-differential incidences of Cryptosporidium parvum infection...
  82. pmc Randomised study of effect of different doses of vitamin A on childhood morbidity and mortality
    Christine Stabell Benn
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    BMJ 331:1428-32. 2005
    ..To determine whether the dose of vitamin A currently recommended by the World Health Organization or half this dose gives better protection against childhood morbidity and mortality...
  83. ncbi request reprint Growth, morbidity and mortality after chickenpox infection in young children in Guinea-Bissau
    Anja Poulsen
    Projecto de Saude de Bandim, Guinea Bissau, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    J Infect 51:307-13. 2005
    ..To examine whether chickenpox in children below 2 years of age is associated with post-infection changes in growth, morbidity or mortality...
  84. ncbi request reprint Vaccination technique, PPD reaction and BCG scarring in a cohort of children born in Guinea-Bissau 2000-2002
    Adam Roth
    Bandim Health Project, Apartado 861, Bissau, Guinea Bissau
    Vaccine 23:3991-8. 2005
    ..Considering that these responses are associated with better infant survival, the importance of monitoring vaccination technique and of different BCG strains should be evaluated with respect to infant mortality...
  85. ncbi request reprint The challenge of improving the efficacy of measles vaccine
    May Lill Garly
    Projecto de Saude Bandim, Apartado 861, Bissau, Guinea Bissau
    Acta Trop 85:1-17. 2003
    ..If we are unlikely to get rid of measles and measles vaccine, it might be wise to study further some of the many unanswered questions regarding the long-term effects of measles and measles vaccination...
  86. ncbi request reprint Hepatitis B vaccination associated with higher female than male mortality in Guinea-bissau: an observational study
    May Lill Garly
    Bandim Health Project, Danish Epidemiology Science Centre, Bissau, Guinea Bissau
    Pediatr Infect Dis J 23:1086-92. 2004
    ..We therefore examined whether hepatitis B vaccine (HBV) was associated with sex-specific differences in mortality...
  87. ncbi request reprint Malnourished children and supplementary feeding during the war emergency in Guinea-Bissau in 1998-1999
    Jens Nielsen
    Bandim Health Project, Bissau, Guinea Bissau, and the Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, USA
    Am J Clin Nutr 80:1036-42. 2004
    ..Supplementary feeding programs (SFPs) are intended to mitigate the deterioration of nutritional status and the increase in mortality among malnourished children...
  88. ncbi request reprint The social situation of motherless children in rural and urban areas of Guinea-Bissau
    Tania Nicole Masmas
    Projecto de Saude de Bandim, Bissau, Guinea Bissau
    Soc Sci Med 59:1231-9. 2004
    ..The traditional extended family system appears to be capable of handling motherless children in a non-discriminatory fashion. However, the AIDS epidemic will continue to stress the extended family system and social services to the limit...
  89. ncbi request reprint Revaccination with Bacillus Calmette-Guerin (BCG) vaccine does not reduce morbidity from malaria in African children
    Amabelia Rodrigues
    Projecto de Saude de Bandim, Guine Bissau, Bissau
    Trop Med Int Health 12:224-9. 2007
    ..It is possible that this effect is mediated partly through an effect on malaria, a hypothesis supported by animal studies. We investigated whether revaccination with BCG at 19 months of age reduced morbidity from malaria...
  90. ncbi request reprint Hypothesis: Vitamin A supplementation and childhood mortality: amplification of the non-specific effects of vaccines?
    Christine Stabell Benn
    Projecto de Saude de Bandim, Bissau, Guinea Bissau
    Int J Epidemiol 32:822-8. 2003
    ..We propose that the effect of vitamin A supplementation may depend on the amplification of non-specific effects of vaccines on childhood mortality...
  91. ncbi request reprint [International health at home: bringing the experiences back home with you]
    Peter Aaby
    Statens Serum Institut, Bandim Health Project, Center for Epidemiologisk Grundforskning, København S
    Ugeskr Laeger 168:3015-8. 2006
    ..Examples are given of how observations in Guinea-Bissau have led to reinterpretation of the decline in measles mortality, of the polio model, and of the impact of stopping vaccinations after eradication in the industrialised countries...
  92. ncbi request reprint Hospital surveillance of rotavirus infection and nosocomial transmission of rotavirus disease among children in Guinea-Bissau
    Amaélia Rodrigues
    Projecto de Saude de Bandim, Bissau, Guine Bissau
    Pediatr Infect Dis J 26:233-7. 2007
    ..Vaccination against rotavirus is protective against severe disease. Surveillance of rotavirus infection in developing countries might direct vaccination policy more efficiently...
  93. doi request reprint Vitamin A supplementation and BCG vaccination at birth may affect atopy in childhood: long-term follow-up of a randomized controlled trial
    N Kiraly
    Bandim Health Project, INDEPTH Network, Bissau, Guinea Bissau, Australia Murdoch Childrens Research Institute, Parkville, Vic, Australia Deakin University School of Medicine, Geelong, Vic, Australia
    Allergy 68:1168-76. 2013
    ..We aimed to determine whether neonatal BCG vaccination, vitamin A supplementation and other vaccinations affect atopy in childhood...
  94. ncbi request reprint Thymus size at birth is associated with infant mortality: a community study from Guinea-Bissau
    P Aaby
    Projecto de Saude de Bandim, Bissau, Guinea Bissau
    Acta Paediatr 91:698-703. 2002
    ..27, 95% CI 0.07-1.00), whereas birthweight had a non-significant effect (MR = 0.59, 95% CI 0.24-1.47). After 1 y of age neither birthweight nor thymus size at birth was associated with mortality...
  95. ncbi request reprint The Danish National Birth Cohort--its background, structure and aim
    J Olsen
    Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, Denmark
    Scand J Public Health 29:300-7. 2001
    ..By August 2000. a total of 60,000 pregnant women had been recruited to the study. It is expected that a large number of gene-environmental hypotheses need to be based on case-control analyses within a cohort like this...
  96. ncbi request reprint Duration of secretory IgM and IgA antibodies to respiratory syncytial virus in a community study in Guinea-Bissau
    L G Stensballe
    Projecto de Saude de Bandim, Bissau, Guinea Bissau
    Acta Paediatr 89:421-6. 2000
    ..IgM responses are short-lived among infants and may therefore be used as an indication of recent RSV infection among children with LRI. Using both antigen and IgM detection may significantly improve our detection of RSV infections...
  97. pmc A comparison of ex vivo cytokine production in venous and capillary blood
    M Eriksson
    Projecto de Saude de Bandim, INDEPTH Network, Bissau, Guinea Bissau
    Clin Exp Immunol 150:469-76. 2007
    ..We found significant differences in the production of cytokines between venous and capillary blood. Such differences should be taken into account when setting up immuno-epidemiological studies...
  98. ncbi request reprint Which children come to the health centre for treatment of malaria?
    Poul Erik Kofoed
    Projecto de Saude de Bandim, Guinea Bissau
    Acta Trop 90:17-22. 2004
    ..02). The possibilities of promoting home treatment should be further evaluated, not only to avoid unnecessary visits to the professional health system, but also to decrease the morbidity from acute malaria...
  99. ncbi request reprint Tuberculin reaction, BCG scar, and lower female mortality
    Adam Roth
    Bandim Health Project, Sector for Epidemiology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen, Denmark
    Epidemiology 17:562-8. 2006
    ..In a prospective birth cohort, we examine whether a positive tuberculin skin test and BCG scar in response to BCG immunization were related to better overall survival in Guinea-Bissau and, if so, whether the effect was sex-specific...
  100. ncbi request reprint Does cross-sex transmission increase the severity of polio infection? A study of multiple family cases
    Nete Munk Nielsen
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen
    Scand J Infect Dis 34:273-7. 2002
    ..Cross-sex transmission may increase the severity of polio and mothers may contribute to the higher prevalence of polio cases among boys...
  101. ncbi request reprint Predictive value of soluble haemoglobin scavenger receptor CD163 serum levels for survival in verified tuberculosis patients
    T B Knudsen
    Department of Infectious Diseases, Copenhagen University Hospitals Hvidovre, Copenhagen, Denmark
    Clin Microbiol Infect 11:730-5. 2005
    ..44-5.63). The HRs for concomitant HIV-1 and HIV-2 infection were 6.92 (95% CI, 3.28-14.58) and 2.48 (95% CI, 1.09-5.67), respectively. Thus, sCD163 levels appeared to be an independent predictor of survival in verified TB patients...