Vitamin A supplementation and genital shedding of herpes simplex virus among HIV-1-infected women: a randomized clinical trialJared M Baeten
Department of Epidemiology, University of Washington, Seattle, Washington 98104 2499, USA
J Infect Dis 189:1466-71. 2004
..Vitamin A supplementation is unlikely to decrease HSV shedding and infectivity...
- A comparison of genital HIV-1 shedding and sexual risk behavior among Kenyan women based on eligibility for initiation of HAART according to WHO guidelines
R Scott McClelland
Departments of Medicine, University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104, USA
J Acquir Immune Defic Syndr 41:611-5. 2006
..Guidelines for initiating antiretrovirals are based on markers of advanced disease and are not directly linked to markers of HIV-1 transmission such as viral shedding...
Antiretroviral prophylaxis for HIV prevention in heterosexual men and womenJared M Baeten
Department of Global Health, University of Washington, Seattle, WA 98104, USA
N Engl J Med 367:399-410. 2012
..Antiretroviral preexposure prophylaxis is a promising approach for preventing human immunodeficiency virus type 1 (HIV-1) infection in heterosexual populations...
- Improvement of vaginal health for Kenyan women at risk for acquisition of human immunodeficiency virus type 1: results of a randomized trial
R Scott McClelland
Department of Medicine, University of Washington, Seattle, USA
J Infect Dis 197:1361-8. 2008
..Vaginal infections are common and have been associated with increased risk for acquisition of human immunodeficiency virus type 1 (HIV-1)...
Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysisDeborah Donnell
Statistical Center for HIV AIDS Research and Prevention and the Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Lancet 375:2092-8. 2010
..Initiation of antiretroviral therapy (ART) reduces plasma HIV-1 concentrations. We aimed to assess the effect of ART use by patients infected with HIV-1 on risk of transmission to their uninfected partners...
- Vitamin A deficiency and the acute phase response among HIV-1-infected and -uninfected women in Kenya
Jared M Baeten
Department of Epidemiology, University of Washington, Seattle 98104 2499, USA
J Acquir Immune Defic Syndr 31:243-9. 2002
..These results provide possible explanations for the disparity between observational studies and randomized trials of vitamin A for HIV-1 infection...
- A decrease in albumin in early HIV type 1 infection predicts subsequent disease progression
Susan M Graham
Department of Medicine, University of Washington, Seattle, Washington 98104, USA
AIDS Res Hum Retroviruses 23:1197-200. 2007
..0, p = 0.008). Trends for an increased risk of mortality were also seen. A greater decrease in albumin levels accompanying HIV-1 acquisition may be a marker for changes in early infection associated with more rapid disease progression...
- Relationship between markers of HIV-1 disease progression and serum beta-carotene concentrations in Kenyan women
Jared M Baeten
Department of Medicine, University of Washington, Seattle, WA 98104, USA
Int J STD AIDS 18:202-6. 2007
....
- Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial
R Scott McClelland
Department of Medicine, University of Washington, Seattle, WA 98104, USA
J Acquir Immune Defic Syndr 37:1657-63. 2004
..The potential benefit of micronutrient supplementation in HIV-1-seropositive women should be considered in relation to the potential for increased infectivity...
- Determinants of per-coital-act HIV-1 infectivity among African HIV-1-serodiscordant couples
James P Hughes
Department of Biostatistics, University of Washington, Seattle 98195 7232, USA
J Infect Dis 205:358-65. 2012
..Knowledge of factors that affect per-act infectivity of human immunodeficiency virus type 1 (HIV-1) is important for designing HIV-1 prevention interventions and for the mathematical modeling of the spread of HIV-1...
- Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
Renee Heffron
Department of Epidemiology, University of Washington, Seattle, WA, USA
Lancet Infect Dis 12:19-26. 2012
..We aimed to assess the association between hormonal contraceptive use and risk of HIV-1 acquisition by women and HIV-1 transmission from HIV-1-infected women to their male partners...
- Prospective study of vaginal bacterial flora and other risk factors for vulvovaginal candidiasis
R Scott McClelland
Department of Medicine, University of Washington, Seattle, WA 98104, USA
J Infect Dis 199:1883-90. 2009
..Our objective was to determine the relationship between vaginal bacterial flora and VVC...
- Increased risk of genital ulcer disease in women during the first month after initiating antiretroviral therapy
Susan M Graham
Departments of Medicine, Epidemiology and Global Health, University of Washington, Seattle, WA 98104 2499, USA
J Acquir Immune Defic Syndr 52:600-3. 2009
..To better define this risk, we monitored 134 women at ART initiation and monthly thereafter...
- Effect of contraceptive methods on natural history of HIV: studies from the Mombasa cohort
Jared M Baeten
University of Washington, Seattle, WA, USA
J Acquir Immune Defic Syndr 38:S18-21. 2005
- Hormonal contraceptive use, herpes simplex virus infection, and risk of HIV-1 acquisition among Kenyan women
Jared M Baeten
Seattle HIV Prevention Trials Unit, Department of Medicine, University of Washington, 9012 Boren Avenue, Seattle, WA 98104, USA
AIDS 21:1771-7. 2007
..A recent study from Uganda and Zimbabwe found that women using hormonal contraception were at increased risk for HIV-1 if they were seronegative for herpes simplex virus type 2 (HSV-2), but not if they were HSV-2 seropositive...
- HIV-1 acquisition and disease progression are associated with decreased high-risk sexual behaviour among Kenyan female sex workers
R Scott McClelland
Departments of Medicine, University of Washington, 325 Ninth Avenue, Seattle, WA 98104, USA
AIDS 20:1969-73. 2006
..Changes in sexual risk behaviour may occur following HIV-1 infection...
- Identification of modifiable factors that affect the genetic diversity of the transmitted HIV-1 population
Manish Sagar
Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, 1100 Fairview Avenue, Seattle, WA 98109, USA
AIDS 18:615-9. 2004
..CONCLUSION: The presence of genital tract infections and hormonal contraceptive use at the time of transmission were associated with the acquisition of multiple HIV-1 variants...
- HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 loads
Jared M Baeten
Department of Medicine, University of Washington, Seattle, WA, USA
J Infect Dis 195:1177-80. 2007
..There were no differences in plasma viral load by HIV-1 subtype during follow-up. HIV-1 subtype D infection is associated with a >2-fold higher risk of death than subtype A infection, in spite of similar plasma HIV-1 loads...
- High levels of cervical HIV-1 RNA during early HIV-1 infection
Ludo Lavreys
Department of Epidemiology, University of Washington, Seattle, Washington, USA
AIDS 20:2389-90. 2006
..43 versus 2.85 log10 copies/swab, P < 0.001). After adjusting for HIV-1-plasma RNA, cervical HIV-1 RNA from 30 days or less after infection was increased by 0.45 log10 copies/swab (P = 0.006)...
- Quantification of genital human immunodeficiency virus type 1 (HIV-1) DNA in specimens from women with low plasma HIV-1 RNA levels typical of HIV-1 nontransmitters
Sarah Benki
Department of Microbiology, University of Washington, Seattle, WA 98109, USA, and Coast Provincial General Hospital, Mombasa, Kenya
J Clin Microbiol 44:4357-62. 2006
..The assay described here can be utilized in future efforts to examine the role of cell-associated HIV-1 in transmission...
- HIV-1 evolution in gag and env is highly correlated but exhibits different relationships with viral load and the immune response
Anne Piantadosi
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
AIDS 23:579-87. 2009
..To evaluate relationships between HIV-1 evolution, including immune evasion, and markers of disease progression during chronic infection...
- Low serum albumin and the acute phase response predict low serum selenium in HIV-1 infected women
Paul K Drain
Department of Medicine, University of Washington, 1959 NE Pacific, A 300 Health Sciences, Box 356340, Seattle, WA 98105, USA
BMC Infect Dis 6:85. 2006
..Low serum selenium has been associated with lower CD4 counts and greater mortality among HIV-1-seropositive individuals, but most studies have not controlled for serum albumin and the presence of an acute phase response...
- Use of serum retinol-binding protein for prediction of vitamin A deficiency: effects of HIV-1 infection, protein malnutrition, and the acute phase response
Jared M Baeten
Department of Epidemiology, University of Washington, Seattle, WA 98104, USA
Am J Clin Nutr 79:218-25. 2004
..The performance of RBP in the context of infection or protein malnutrition, however, has not been evaluated...
- Contribution of HIV-1 infection to acquisition of sexually transmitted disease: a 10-year prospective study
R Scott McClelland
Department of Medicine, University of Washington, Seattle, Washington 98104, USA
J Infect Dis 191:333-8. 2005
..Sexually transmitted diseases (STDs) enhance human immunodeficiency virus (HIV)-1 susceptibility, but few studies have examined the reciprocal effect of HIV-1 on STD acquisition...
- Injectable contraceptive use and genital ulcer disease during the early phase of HIV-1 infection increase plasma virus load in women
Ludo Lavreys
Department of Epidemiology, Medicine, and Biostatistics, University of Washington, Seattle, Washington 98104 2499, USA
J Infect Dis 189:303-11. 2004
..These findings suggest that, in women, the use of DMPA and the presence of GUD during the early phase of HIV-1 infection may influence the natural course of infection...
- A prospective study of risk factors for bacterial vaginosis in HIV-1-seronegative African women
R Scott McClelland
Department of Medicine, University of Washington, Seattle, WA 98104, USA
Sex Transm Dis 35:617-23. 2008
..Bacterial vaginosis (BV) is common and has been associated with increased HIV-1 susceptibility. The objective of this study was to identify risk factors for BV in African women at high risk for acquiring HIV-1...
- HIV-1 infection alters the retinol-binding protein:transthyretin ratio even in the absence of the acute phase response
Jared M Baeten
Department of Epidemiology, University of Washington, Seattle, WA, USA
J Nutr 136:1624-9. 2006
..Our results raise questions about the utility of this measurement given the high prevalence of HIV-1 infection in areas where vitamin A deficiency is common...
- Higher pre-infection vitamin E levels are associated with higher mortality in HIV-1-infected Kenyan women: a prospective study
Susan M Graham
Department of Medicine, University of Washington, Seattle, Washington 98195, USA
BMC Infect Dis 7:63. 2007
..However, vitamin E supplementation has also been reported to increase CCR5 expression, which could increase HIV-1 replication. We hypothesized that vitamin E levels at HIV-1 acquisition may influence disease progression...
- Using plasma viral load to guide antiretroviral therapy initiation to prevent HIV-1 transmission
Pamela M Murnane
Department of Epidemiology, University of Washington, Seattle, Washington, United States of America
PLoS ONE 7:e51192. 2012
..Because the quantity of HIV-1 in plasma is the primary predictor of HIV-1 transmission, consideration of plasma viral load in ART initiation guidelines is warranted...
- Genital Inflammation Predicts HIV-1 Shedding Independent of Plasma Viral Load and Systemic Inflammation
Catherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
J Acquir Immune Defic Syndr 61:436-40. 2012
..Thus, efforts to decrease HIV-1 transmission must take into account the role of local inflammation, which is not necessarily reflected in plasma measurements...
- Outside sexual partnerships and risk of HIV acquisition for HIV uninfected partners in African HIV serodiscordant partnerships
Patrick Ndase
Department of Global Health, University of Washington, Seattle, 98104, USA
J Acquir Immune Defic Syndr 59:65-71. 2012
..As African countries scale-up couples HIV testing, little is known about sexual behaviors and HIV risk for HIV-uninfected partners in known HIV-serodiscordant relationships...
- Hormonal contraception and risk of cervical infections among HIV-1-seropositive Kenyan women
Ludo Lavreys
Departments of Epidemiology and Medicine, University of Washington, Seattle 98104 2499, USA
AIDS 18:2179-84. 2004
..To evaluate the relationship between hormonal contraceptive use and the acquisition of cervical sexually transmitted infections (STI) among HIV-1-infected women...
- Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression
Anne Piantadosi
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Virol 83:10269-74. 2009
..Thus, a broad NAb response results from a high level of antigenic stimulation early in infection, which likely accounts for prior observations that greater NAb response breadth is associated with a higher viral load later in infection...
- Higher set point plasma viral load and more-severe acute HIV type 1 (HIV-1) illness predict mortality among high-risk HIV-1-infected African women
Ludo Lavreys
Department of Epidemiology, Medicine, and Biostatistics, University of Washington, Seattle, WA 98104 2499, USA
Clin Infect Dis 42:1333-9. 2006
..We used data from a prospective cohort study of female sex workers in Mombasa, Kenya, who were followed up monthly from before the date of HIV-1 infection...
- A prospective study of contraceptive use among African women in HIV-1 serodiscordant partnerships
Renee Heffron
Department of Epidemiology, University of Washington, Seattle, WA 98104, USA
Sex Transm Dis 37:621-8. 2010
..Few studies have explored contraceptive use in HIV-1 serodiscordant couples, a population at high risk for HIV-1 transmission...
- Infection with Trichomonas vaginalis increases the risk of HIV-1 acquisition
R Scott McClelland
Department of Medicine, University of Washington, Seattle, WA 98104, USA
J Infect Dis 195:698-702. 2007
..52-fold (95% confidence interval, 1.04-2.24-fold) increased risk of HIV-1 acquisition after adjustment for potential confounding factors. Treatment and prevention of T. vaginalis infection could reduce HIV-1 risk in women...
- Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial
Jairam R Lingappa
Department of Global Health, Seattle, WA, USA
Lancet 375:824-33. 2010
..Daily suppression of this herpes virus reduces plasma HIV-1 concentrations, but whether it delays HIV-1 disease progression is unknown. We investigated the effect of acyclovir on HIV-1 progression...
- Quantifying ongoing HIV-1 exposure in HIV-1-serodiscordant couples to identify individuals with potential host resistance to HIV-1
Romel D Mackelprang
Department of Global Health, University of Washington, WA, USA
J Infect Dis 206:1299-308. 2012
..We developed a novel approach for quantifying HIV-1 exposure to identify individuals remaining HIV-1 uninfected despite persistent high exposure...
- Female-to-male infectivity of HIV-1 among circumcised and uncircumcised Kenyan men
Jared M Baeten
Department of Epidemiology, University of Washington, Seattle, Washington 98104 2499, USA
J Infect Dis 191:546-53. 2005
..e., infectivity) for circumcised and uncircumcised men, by use of detailed accounts of sexual behavior in a population with multiple partnerships...
- Willingness of Kenyan HIV-1 serodiscordant couples to use antiretroviral-based HIV-1 prevention strategies
Renee Heffron
Department of Epidemiology, University of Washington, 325 Ninth Avenue, Box 359927, Seattle, WA 98104, USA
J Acquir Immune Defic Syndr 61:116-9. 2012
..Antiretroviral treatment (ART) and pre-exposure prophylaxis (PrEP) have demonstrated efficacy as new human immunodeficiency virus-1 (HIV-1) prevention approaches for HIV-1 serodiscordant couples...
- Characteristics of HIV-1 serodiscordant couples enrolled in a clinical trial of antiretroviral pre-exposure prophylaxis for HIV-1 prevention
Andrew Mujugira
Department of Global Health, University of Washington, Seattle, Washington, United States of America
PLoS ONE 6:e25828. 2011
..We describe the trial design and characteristics of the study cohort...
- Estimating the impact of plasma HIV-1 RNA reductions on heterosexual HIV-1 transmission risk
Jairam R Lingappa
Department of Global Health, University of Washington, Seattle, Washington, United States of America
PLoS ONE 5:e12598. 2010
....
- Hormonal contraception and risk of HIV-1 acquisition: results of a 10-year prospective study
Ludo Lavreys
Departments of Epidemiology and Medicine, University of Washington, Seattle, WA, USA
AIDS 18:695-7. 2004
- Vitamin A supplementation and human immunodeficiency virus type 1 shedding in women: results of a randomized clinical trial
Jared M Baeten
Department of Epidemiology, University of Washington, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
J Infect Dis 185:1187-91. 2002
..Vitamin A supplementation is unlikely to decrease the infectivity of women infected with HIV-1...
- Infection with multiple human immunodeficiency virus type 1 variants is associated with faster disease progression
Manish Sagar
Divisions of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington 98109, USA
J Virol 77:12921-6. 2003
..01) 4 to 24 months after infection compared to women who were infected with a single viral genotype. These studies suggest that early HIV-1 genetic diversity is linked to faster disease progression...
- Vaginal washing and increased risk of HIV-1 acquisition among African women: a 10-year prospective study
R Scott McClelland
Department of Medicine, University of Washington, Seattle, WA 98104, USA
AIDS 20:269-73. 2006
..No prospective study has examined the risk of HIV-1 acquisition associated with vaginal washing, although intravaginal practices have been identified as potentially important contributors to HIV-1 susceptibility...
- Hormonal contraceptive use and risk of HIV-1 disease progression
Renee Heffron
Department of Epidemiology, University of Washington, Seattle, Washington 98104, USA
AIDS 27:261-7. 2013
..For HIV-1-infected women, hormonal contraception prevents unintended pregnancy, excess maternal morbidity, and vertical HIV-1 transmission. Hormonal contraceptives are widely used but their effects on HIV-1 disease progression are unclear...
- HIV-1 prevention for HIV-1 serodiscordant couples
Kathryn Curran
International Clinical Research Center, Department of Global Health, University of Washington, Seattle, WA 98104, USA
Curr HIV/AIDS Rep 9:160-70. 2012
....
- Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure
Jairam R Lingappa
Department of Global Health, University of Washington, Seattle, Washington, United States of America
PLoS ONE 6:e28632. 2011
..To minimize misclassification of HIV-1 risk, we quantified HIV-1 exposure, using data including plasma HIV-1 concentrations, gender, and condom use...
- Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2
C Celum
Department of Global Health, University of Washington, Harborview Medical Center, 325 Ninth Ave, Box 359927, Seattle, WA 98104, USA
N Engl J Med 362:427-39. 2010
..Therapy to suppress HSV-2 reduces the frequency of reactivation of HSV-2 as well as HIV-1 levels, suggesting that suppression of HSV-2 may reduce the risk of transmission of HIV-1...
- High Mycoplasma genitalium organism burden is associated with shedding of HIV-1 DNA from the cervix
Lisa E Manhart
Department of Epidemiology, University of Washington, Seattle, WA 98104 2499, USA
J Infect Dis 197:733-6. 2008
..genitalium-negative women (adjusted OR, 2.9 [95% confidence interval, 1.1-7.6]), yet this did not appear to be mediated by traditional measures of cervical inflammation (elevated polymorphonuclear leukocyte count)...
- Herpes simplex virus type 2 suppressive therapy with acyclovir or valacyclovir does not select for specific HIV-1 resistance in HIV-1/HSV-2 dually infected persons
Jared M Baeten
Department of Global Health, University of Washington, Seattle, Washington, USA
J Infect Dis 203:117-21. 2011
..No V75I cases were detected (95% confidence interval, 0%-2.2%). These prospective in vivo studies suggest that standard-dose acyclovir or valacyclovir does not select for HIV-1 resistance...
- A post-trial assessment of factors influencing study drug adherence in a randomized biomedical HIV-1 prevention trial
Shevin T Jacob
Department of Medicine, University of Washington, Seattle, WA, USA
AIDS Behav 15:897-904. 2011
....
- Virus load during primary Human Immunodeficiency Virus (HIV) type 1 infection is related to the severity of acute HIV illness in Kenyan women
Ludo Lavreys
University of Washington, Seattle, WA, 98104, USA
Clin Infect Dis 35:77-81. 2002
..4 log(10) copies/mL...
- Immune response to hepatitis B virus vaccination among HIV-1 infected and uninfected adults in Kenya
Elizabeth Irungu
Department of Epidemiology, University of Washington, Seattle, WA 98104, USA
J Infect Dis 207:402-10. 2013
....
- Reducing HIV-1 transmission through prevention strategies targeting HIV-1-seropositive individuals
R Scott McClelland
Department of Medicine, University of Washington, Seattle, WA, USA
J Antimicrob Chemother 57:163-6. 2006
..Further work is urgently needed to develop, test and implement comprehensive strategies for prevention in positives...
- Herpes simplex virus (HSV)-suppressive therapy decreases plasma and genital HIV-1 levels in HSV-2/HIV-1 coinfected women: a randomized, placebo-controlled, cross-over trial
Jared M Baeten
Department of Global Health, University of Washington, Seattle, WA 98104, USA
J Infect Dis 198:1804-8. 2008
..001]), as was cervical HIV-1 level (-0.35 log10 copies/swab, a 55% decrease [P < .001]). Suppressive HSV-2 therapy has the potential to reduce HIV-1 infectiousness and slow HIV-1 disease progression...
- Performance of the Focus HerpeSelect-2 enzyme immunoassay for the detection of herpes simplex virus type 2 antibodies in seven African countries
Andrew Mujugira
Department of Global Health, University of Washington, Seattle, Washington, USA
Sex Transm Infect 87:238-41. 2011
..To compare the performance of the Focus HerpeSelect-2 enzyme immunoassay (EIA) with the gold standard herpes simplex virus (HSV) type 2 western blot, among HIV-1-uninfected men and women in east and southern Africa...
- Correlates of human herpesvirus 8 seropositivity among heterosexual men in Kenya
Jared M Baeten
Department of Epidemiology, University of Washington, Seattle 98104-2499, USA
AIDS 16:2073-8. 2002
..Prospective studies of HHV-8 acquisition in heterosexual African populations are needed to demonstrate whether safer sexual practices can reduce transmission...
- Genital HIV-1 RNA predicts risk of heterosexual HIV-1 transmission
Jared M Baeten
Department of Global Health, University of Washington, Seattle, WA 98195, USA
Sci Transl Med 3:77ra29. 2011
..These data suggest that HIV-1 RNA in genital secretions could be used as a marker of HIV-1 sexual transmission risk...
- Plasma viral loads during early HIV-1 infection are similar in subtype C- and non-subtype C-infected African seroconverters
Mary S Campbell
Department of Medicine, University of Washington, Seattle, WA 98195, USA
J Infect Dis 207:1166-70. 2013
..Our data do not support the hypothesis that higher early viral load accounts for the rapid spread of HIV-1 subtype C in southern Africa...
- Clinical and virologic response to episodic acyclovir for genital ulcers among HIV-1 seronegative, herpes simplex virus type 2 seropositive African women: a randomized, placebo-controlled trial
Jared M Baeten
Department of Global Health, University of Washington, Seattle, WA 98104, USA
Sex Transm Dis 39:21-4. 2012
..1 vs. 6.0 days) and cessation of herpes simplex virus shedding (HR = 1.88, P = 0.008; mean, 3.0 vs. 5.0 days) compared with placebo, similar to results of studies in high-income countries (ClinicalTrials.gov registration NCT00808405)...
- Male circumcision and risk of male-to-female HIV-1 transmission: a multinational prospective study in African HIV-1-serodiscordant couples
Jared M Baeten
University of Washington, WA, USA
AIDS 24:737-44. 2010
....
- The impact of early monitored management on survival in hospitalized adult Ugandan patients with severe sepsis: a prospective intervention study*
Shevin T Jacob
Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA
Crit Care Med 40:2050-8. 2012
..In sub-Saharan Africa, sepsis is an important cause of mortality. Optimal sepsis management including fluid resuscitation, early antibiotic administration, and patient monitoring is limited by lack of supplies and skilled health workers...
- Measuring the infectiousness of persons with HIV-1: opportunities for preventing sexual HIV-1 transmission
Jared M Baeten
Department of Epidemiology, University of Washington, Seattle 98104 2499, USA
Curr HIV Res 1:69-86. 2003
..Unresolved issues related to optimal measurement techniques for genital HIV-1, promises and limitations of antiretroviral therapy and vaccines to reduce infectiousness, and other intervention strategies still in development are reviewed...
- The influence of hormonal contraceptive use on HIV-1 transmission and disease progression
Jared M Baeten
Department of Medicine, University of Washington, Seattle, WA, USA
Clin Infect Dis 45:360-9. 2007
..Safe and effective contraceptive choices are essential for women with and at risk for HIV-1 infection. Thus, understanding the effect, if any, of hormonal contraception on HIV-1 disease among women is a public health priority...
- Hormonal contraception and HIV-1 transmission
Catherine A Blish
Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109, USA
Am J Reprod Immunol 65:302-7. 2011
..It is clear that hormonal contraceptives are not protective against HIV-1 infection and that dual protection with condoms should be the goal for women using hormonal contraception...
- Tenofovir-based pre-exposure prophylaxis for HIV prevention: evolving evidence
Connie Celum
Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, Washington 98104, USA
Curr Opin Infect Dis 25:51-7. 2012
..Preexposure prophylaxis (PrEP) trials and future directions are summarized...
- Risk Factors for HSV-2 Infection among Sexual Partners of HSV-2/HIV-1 Co-Infected Persons
Andrew Mujugira
Department of Global Health, University of Washington, Seattle, WA, USA
BMC Res Notes 4:64. 2011
..abstract:..
- Re: distinguishing the temporal association between women's intravaginal practices and risk of human immunodeficiency virus infection: a prospective study of South African women
R Scott McClelland
Am J Epidemiol 165:474-5; author reply 475-6. 2007
