Melatonin, serotonin, and tryptamine in some egyptian food and medicinal plantsFarid A Badria
Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
J Med Food 5:153-7. 2002
..3 ng/100 g, respectively. On the other hand, potato samples were free from all indolamines. Pomegranate and strawberry showed a low level of indolamines (8-12 microg/g serotonin, 4-9 microg/g tryptamine, and 13-29 ng/100 g melatonin)...
- Evaluation of cytotoxic compounds from calligonum comosum L. growing in Egypt
Farid A Badria
Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
Z Naturforsch C 62:656-60. 2007
..All isolated compounds were tested for their cytotoxicity and antioxidant activity. Compound 2 showed the best cytotoxic and antioxidant activity...
- In vitro study of flavonoids, fatty acids, and steroids on proliferation of rat hepatic stellate cells
Farid A Badria
Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
Z Naturforsch C 60:139-42. 2005
..These results revealed that the compounds which effectively blocked HSC proliferation may be beneficial in liver fibrosis. Structure-activity relationships (SAR) may provide a basis for rational structure modification...
- Natural products for dental caries prevention
Farid A Badria
Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
J Med Food 7:381-4. 2004
..These compounds represent three major classes of natural products: tannins, alkaloids, and flavonoids. Further study for possible application of these compounds as inhibitors for dental caries is underway...
- Immunomodulatory triterpenoids from the oleogum resin of Boswellia carterii Birdwood
Farid A Badria
Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt
Z Naturforsch C 58:505-16. 2003
..The lymphocyte transformation assay of the isolated compounds proved that the total extract retained more activity than that of any of the purified compounds...
- Antioxidant and immunomodulatory constituents of henna leaves
Botros R Mikhaeil
Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, 35516 Mansoura, Egypt
Z Naturforsch C 59:468-76. 2004
..The ABTS [2,2'-azino-bis (3-ethyl benzthiazoline-6-sulfonic acid)], free radical scavenging assay depicted that all isolated compounds exhibited antioxidant activity comparable to that of ascorbic acid...
- Chemistry and immunomodulatory activity of frankincense oil
Botros R Mikhaeil
Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
Z Naturforsch C 58:230-8. 2003
..Biologically, the oil exhibited a strong immunostimulant activity (90% lymphocyte transformation) when assessed by a lymphocyte proliferation assay...
Synthesis and antitumor evaluation of some new 1,3,4-oxadiazole-based heterocyclesSamir Bondock
Department of Chemistry, Faculty of Science, Mansoura University, ET 35516 Mansoura, Egypt
Eur J Med Chem 48:192-9. 2012
..Transformation of 1,3,4-oxadiazole 2 to N-(6-amino-7H-pyrazolo[5,1-c][1,2,4]triazol-3-yl)benzamide (15) diminished the antitumor activity...
- Synthesis of new 2-naphthyl ethers and their protective activities against DNA damage induced by bleomycin-iron
Bakr F Abdel-Wahab
Applied Organic Chemistry Department, National Research Center, Dokki, Giza, Egypt
Chem Pharm Bull (Tokyo) 57:1348-51. 2009
..Compound 2 showed the greatest protection against DNA damage, thus diminishing chromogen formation between the damaged DNA and thiobarbituric acid...
- Stereoselective synthesis and antiviral activity of (1E,2Z,3E)-1-(piperidin-1-yl)-1-(arylhydrazono)-2-[(benzoyl/benzothiazol-2-oyl)hydrazono]-4-(aryl(1))but-3-enes
Hatem A Abdel-Aziza
Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
Arch Pharm (Weinheim) 343:152-9. 2010
..Compound 7d reduced the number of viral plaques of herpes simplex type-1 (HSV-1) by 67%, with respect to the effect of reference drug Aphidicolin...
- DNA binding, antiviral activities and cytotoxicity of new furochromone and benzofuran derivatives
Omaima Mohamed Abdelhafez
Chemistry of Natural Products, National Research Center, Dokki, Cairo 72427, Egypt
Arch Pharm Res 34:1623-32. 2011
..Moreover, compound 2 also was the most active as antiviral agent toward HS-I virus and compounds 6, 7, 15, 14, 16a, and 18a were found to be moderately active. CD(50) of the active compounds were also measured...
- Cytotoxic and protective DNA damage of three new diterpenoids from the brown alga Dictoyota dichotoma
Seif Eldin N Ayyad
Department of Chemistry, Faculty of Science, King Abdulaziz University, P O Box 80203, Jeddah 21589, Saudi Arabia
Eur J Med Chem 46:175-82. 2011
..Compounds 3 and 9 have potent activity against DNA damage, cytotoxicity against WI-38, HepG2, and MCF-7 cell lines, and antioxidant using ABTS and erythrocytes hemolysis...
- Natural anti-inflammatory products and leukotriene inhibitors as complementary therapy for bronchial asthma
Maha E Houssen
Department of Biochemistry, Faculty of Pharmacy, University of Beni Sueif, Beni Sueif 62514, Egypt
Clin Biochem 43:887-90. 2010
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