Ramy K Aziz

Summary

Publications

  1. pmc SEED servers: high-performance access to the SEED genomes, annotations, and metabolic models
    Ramy K Aziz
    Computation Institute, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e48053. 2012
  2. pmc The RAST Server: rapid annotations using subsystems technology
    Ramy K Aziz
    Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA
    BMC Genomics 9:75. 2008
  3. pmc Transposases are the most abundant, most ubiquitous genes in nature
    Ramy K Aziz
    Computation Institute, University of Chicago, Chicago, IL 60637, USA
    Nucleic Acids Res 38:4207-17. 2010
  4. pmc The National Microbial Pathogen Database Resource (NMPDR): a genomics platform based on subsystem annotation
    Leslie Klis McNeil
    National Center for Supercomputing Applications, Urbana, IL 61801, USA
    Nucleic Acids Res 35:D347-53. 2007
  5. pmc Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development
    Jeffrey B Locke
    Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America
    PLoS ONE 3:e2824. 2008
  6. pmc Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes
    Ramy K Aziz
    Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis 38163, USA
    J Bacteriol 187:3311-8. 2005
  7. ncbi request reprint Streptococcal mitogenic exotoxin, SmeZ, is the most susceptible M1T1 streptococcal superantigen to degradation by the streptococcal cysteine protease, SpeB
    Mohammed M Nooh
    Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Biol Chem 281:35281-8. 2006

Collaborators

Detail Information

Publications7

  1. pmc SEED servers: high-performance access to the SEED genomes, annotations, and metabolic models
    Ramy K Aziz
    Computation Institute, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e48053. 2012
    ..Large integrations of genomic data represent one of the major intellectual resources driving research in biology, and programmatic access to the SEED data will provide significant utility to a broad collection of potential users...
  2. pmc The RAST Server: rapid annotations using subsystems technology
    Ramy K Aziz
    Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA
    BMC Genomics 9:75. 2008
    ..The number of prokaryotic genome sequences becoming available is growing steadily and is growing faster than our ability to accurately annotate them...
  3. pmc Transposases are the most abundant, most ubiquitous genes in nature
    Ramy K Aziz
    Computation Institute, University of Chicago, Chicago, IL 60637, USA
    Nucleic Acids Res 38:4207-17. 2010
    ..By securing their own replication and dissemination, transposases guarantee to thrive so long as nucleic acid-based life forms exist...
  4. pmc The National Microbial Pathogen Database Resource (NMPDR): a genomics platform based on subsystem annotation
    Leslie Klis McNeil
    National Center for Supercomputing Applications, Urbana, IL 61801, USA
    Nucleic Acids Res 35:D347-53. 2007
    ..Essentiality data collated from genome-wide studies have been curated. Drug target identification and high-throughput, in silico, compound screening are in development...
  5. pmc Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development
    Jeffrey B Locke
    Department of Pediatrics, University of California San Diego, La Jolla, California, United States of America
    PLoS ONE 3:e2824. 2008
    ..Through pyrosequencing of the S. iniae genome we have identified two gene homologues to classical surface-anchored streptococcal virulence factors: M-like protein (simA) and C5a peptidase (scpI)...
  6. pmc Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes
    Ramy K Aziz
    Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis 38163, USA
    J Bacteriol 187:3311-8. 2005
    ..Y, replacing it with a different module identical to that found on a related M3 phage. Taken together, the data demonstrate that mosaicism of the GAS prophages has contributed to the emergence and diversification of the M1T1 subclone...
  7. ncbi request reprint Streptococcal mitogenic exotoxin, SmeZ, is the most susceptible M1T1 streptococcal superantigen to degradation by the streptococcal cysteine protease, SpeB
    Mohammed M Nooh
    Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Biol Chem 281:35281-8. 2006
    ..The study provides evidence for the effect of subtle structural differences between highly similar SAgs on their biological activity...