Adile Ayati

Summary

Publications

  1. Ayati A, Emami S, Foroumadi A. The importance of triazole scaffold in the development of anticonvulsant agents. Eur J Med Chem. 2016;109:380-92 pubmed publisher
    ..In this article, we have tried to summarize the latest efforts which have been made in the design and development of triazole-derived anticonvulsant agents. ..
  2. Mirzaei H, Emami S. Recent advances of cytotoxic chalconoids targeting tubulin polymerization: Synthesis and biological activity. Eur J Med Chem. 2016;121:610-639 pubmed publisher
    ....
  3. Ansari M, Emami S. ?-Ionone and its analogs as promising anticancer agents. Eur J Med Chem. 2016;123:141-154 pubmed publisher
    ..In this paper, we reviewed the potentialities of ?-ionone and related compounds in cancer prevention and chemotherapy. ..
  4. Ayati A, Esmaeili R, Moghimi S, Oghabi Bakhshaiesh T, Eslami S Z, Majidzadeh A K, et al. Synthesis and biological evaluation of 4-amino-5-cinnamoylthiazoles as chalcone-like anticancer agents. Eur J Med Chem. 2018;145:404-412 pubmed publisher
    ..6 μg/ml). Flow cytometric analyses revealed that the prototype compound 3e can prevent the proliferation of HepG2 cells by blockade of the cell cycle at the G2 phase and induction of apoptosis. ..
  5. Emami S, Tavangar P, Keighobadi M. An overview of azoles targeting sterol 14?-demethylase for antileishmanial therapy. Eur J Med Chem. 2017;135:241-259 pubmed publisher
    ..This review may help medicinal chemists for design of new azole-derived antileishmanial drugs. ..
  6. Haghighijoo Z, Firuzi O, Hemmateenejad B, Emami S, Edraki N, Miri R. Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer's disease. Bioorg Chem. 2017;74:126-133 pubmed publisher
    ..These results demonstrate that quinazolinone-hydrazone derivatives represent a valuable scaffold for the discovery of novel non-peptidic BACE1 inhibitors. ..
  7. Mirzaei H, Shokrzadeh M, Modanloo M, Ziar A, Riazi G, Emami S. New indole-based chalconoids as tubulin-targeting antiproliferative agents. Bioorg Chem. 2017;75:86-98 pubmed publisher
    ..Docking studies with tubulin indicated that compound 9b could bind to the colchicine binding site. ..

Locale

Detail Information

Publications7

  1. Ayati A, Emami S, Foroumadi A. The importance of triazole scaffold in the development of anticonvulsant agents. Eur J Med Chem. 2016;109:380-92 pubmed publisher
    ..In this article, we have tried to summarize the latest efforts which have been made in the design and development of triazole-derived anticonvulsant agents. ..
  2. Mirzaei H, Emami S. Recent advances of cytotoxic chalconoids targeting tubulin polymerization: Synthesis and biological activity. Eur J Med Chem. 2016;121:610-639 pubmed publisher
    ....
  3. Ansari M, Emami S. ?-Ionone and its analogs as promising anticancer agents. Eur J Med Chem. 2016;123:141-154 pubmed publisher
    ..In this paper, we reviewed the potentialities of ?-ionone and related compounds in cancer prevention and chemotherapy. ..
  4. Ayati A, Esmaeili R, Moghimi S, Oghabi Bakhshaiesh T, Eslami S Z, Majidzadeh A K, et al. Synthesis and biological evaluation of 4-amino-5-cinnamoylthiazoles as chalcone-like anticancer agents. Eur J Med Chem. 2018;145:404-412 pubmed publisher
    ..6 μg/ml). Flow cytometric analyses revealed that the prototype compound 3e can prevent the proliferation of HepG2 cells by blockade of the cell cycle at the G2 phase and induction of apoptosis. ..
  5. Emami S, Tavangar P, Keighobadi M. An overview of azoles targeting sterol 14?-demethylase for antileishmanial therapy. Eur J Med Chem. 2017;135:241-259 pubmed publisher
    ..This review may help medicinal chemists for design of new azole-derived antileishmanial drugs. ..
  6. Haghighijoo Z, Firuzi O, Hemmateenejad B, Emami S, Edraki N, Miri R. Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer's disease. Bioorg Chem. 2017;74:126-133 pubmed publisher
    ..These results demonstrate that quinazolinone-hydrazone derivatives represent a valuable scaffold for the discovery of novel non-peptidic BACE1 inhibitors. ..
  7. Mirzaei H, Shokrzadeh M, Modanloo M, Ziar A, Riazi G, Emami S. New indole-based chalconoids as tubulin-targeting antiproliferative agents. Bioorg Chem. 2017;75:86-98 pubmed publisher
    ..Docking studies with tubulin indicated that compound 9b could bind to the colchicine binding site. ..