Impact of age on management and outcome of acute coronary syndrome: observations from the Global Registry of Acute Coronary Events (GRACE)Alvaro Avezum
Dante Pazzanese Cardiology Institute, Research Division, Sao Paulo, Brazil
Am Heart J 149:67-73. 2005
..Evidence-based cardiac therapies are underutilized in elderly patients. We assessed differences in practice patterns, comorbidities, and in-hospital event rates, by age and type of acute coronary syndrome (ACS)...
- [Risk factors associated with acute myocardial infarction in the São Paulo metropolitan region: a developed region in a developing country]
Alvaro Avezum
Instituto Dante Pazzanese de Cardiologia, Hospital do Coração, Sao Paulo, SP
Arq Bras Cardiol 84:206-13. 2005
..To identify the risk factors associated with acute myocardial infarction (AMI) and their respective powers of association in the São Paulo metropolitan region...
- Comparison between cardiac troponin I and CK-MB mass in acute coronary syndrome without st elevation
Elizabete Silva dos Santos
Instituto Dante Pazzanese de Cardiologia, Sao Paulo, SP, Brazil
Arq Bras Cardiol 96:179-87. 2011
..There is uncertainty as to the comparative prognostic value between cardiac troponin I (cTnI) and CK-MB in acute coronary syndrome (ACS)...
Magnitude and prognosis associated with ventricular arrhythmias in patients hospitalized with acute coronary syndromes (from the GRACE Registry)Alvaro Avezum
Dante Pazzanese Institute of Cardiology, Research Division, Sao Paulo, Sao Paulo, Brazil
Am J Cardiol 102:1577-82. 2008
..57, 95% confidence interval 1.27 to 1.95). In conclusion, development of VA during hospitalization for acute coronary syndrome was associated with higher in-hospital and 6-month mortalities...
- Use of proven therapies in non-ST-elevation acute coronary syndromes according to evidence-based risk stratification
Gustavo B F Oliveira
Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil
Am Heart J 153:493-9. 2007
..Our objective was to evaluate the relationship between risk stratification and therapeutic decision making in patients with non-ST-segment elevation acute coronary syndromes...
- The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease
J Antonio Marin-Neto
Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Ribeirao Preto, SP, Brasil
Mem Inst Oswaldo Cruz 104:319-24. 2009
..The full-scale study determines whether antitrypanosomal therapy with benznidazole reduces mortality and other major cardiovascular clinical outcomes in patients with chronic Chagas heart disease...
- Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: the BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT)
Jose Antonio Marin-Neto
Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
Am Heart J 156:37-43. 2008
..However, the efficacy of trypanocidal therapy in preventing clinical complications in patients with preexisting cardiac disease is unknown...
- [The impact of diabetes mellitus on the mortality of acute coronary syndromes]
Juarez R de Braga
Divisão de Pesquisa, Instituto Dante Pazzanese de Cardiologia, Sao Paulo, SP, Brazil
Arq Bras Endocrinol Metabol 51:275-80. 2007
....
- Risk factors for myocardial infarction in Brazil
Leopoldo S Piegas
Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil
Am Heart J 146:331-8. 2003
..Brazil is one of the largest countries in Latin America and the contemporary evaluation of risk factors for AMI is crucial for a more efficacious disease management...
- [Electrical cardioversion and myocardial injury: evaluation by new cardiac injury markers]
Elizabete Silva dos Santos
Instituto Dante Pazzanese de Cardiologia, Sao Paulo, SP
Arq Bras Cardiol 86:191-7. 2006
..Evaluate, based on the evolution of new biochemical markers of cardiac damage, if electrical cardioversion (ECV) causes myocardial injury...
Brazilian Sepsis Epidemiological Study (BASES study)Eliezer Silva
Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Crit Care 8:R251-60. 2004
..This study was designed to verify the actual incidence density and outcome of sepsis in Brazilian ICUs. We also assessed the association between the Consensus Conference criteria and outcome..
- [Evidence based cardiology. Some necessary clarifications]
Otavio Berwanger
Centro de Pesqusa Clínica, IEP, Hospital Albert Einstein, Instituto Dante Pazzanese de Cardiologia, Sao Paulo, SP
Arq Bras Cardiol 83:357-9. 2004
- [Evidence-based cardiology: where to find evidence]
Otavio Berwanger
Instituto Dante Pazzanese de Cardiologia, Sao Paulo, SP
Arq Bras Cardiol 86:56-60. 2006
- Two-year outcomes in patients admitted with non-ST elevation acute coronary syndrome: results of the OASIS registry 1 and 2
Dorairaj Prabhakaran
McMaster University, Hamilton, Canada
Indian Heart J 57:217-25. 2005
....
- Interactions between heparins, glycoprotein IIb/IIIa antagonists, and coronary intervention. The Global Registry of Acute Coronary Events (GRACE)
David Brieger
Concord Hospital, Sydney, Australia
Am Heart J 153:960-9. 2007
....
- Management and 6-month outcomes in elderly and very elderly patients with high-risk non-ST-elevation acute coronary syndromes: The Global Registry of Acute Coronary Events
Gerard Devlin
Department of Cardiology, Waikato Hospital, Hamilton, New Zealand
Eur Heart J 29:1275-82. 2008
....
- Comparison of utilization of statin therapy at hospital discharge and six-month outcomes in patients with an acute coronary syndrome and serum low-density lipoprotein>or=100 mg/dl versus<100 mg/dl
Frederick A Spencer
Department of Medicine, McMaster University, Faculty of Health Sciences, Hamilton, Ontario, Canada, and Coronary Care Unit, Concord Hospital, Sydney, Australia
Am J Cardiol 100:913-8. 2007
....
- Risk factors for acute myocardial infarction in Latin America: the INTERHEART Latin American study
Fernando Lanas
Facultad de Medicina, Universidad de La Frontera M, Montt 112 Temuco, Chile
Circulation 115:1067-74. 2007
..Current knowledge of the impact of cardiovascular risk factors in Latin America is limited...
- Stenting and glycoprotein IIb/IIIa inhibition in patients with acute myocardial infarction undergoing percutaneous coronary intervention: findings from the global registry of acute coronary events (GRACE)
Gilles Montalescot
Service de cardiologie, Pitie Salpetriere Hospital, Paris, France
Catheter Cardiovasc Interv 60:360-7. 2003
..4% among patients who received neither GP IIb/IIIa inhibitors nor a stent, compared to patients who received both GP IIb/IIIa inhibitors and a stent (7.3%), GP IIb/IIIa inhibitors alone (12.8%), or a stent alone (6.7%)...
- Extent of, and factors associated with, delay to hospital presentation in patients with acute coronary disease (the GRACE registry)
Robert J Goldberg
University of Massachusetts Medical School, Worcester, Massachusetts, USA
Am J Cardiol 89:791-6. 2002
....
- Effectiveness of primary percutaneous coronary intervention compared with that of thrombolytic therapy in elderly patients with acute myocardial infarction
Rajendra H Mehta
University of Michigan, Ann Arbor, Mich, USA
Am Heart J 147:253-9. 2004
....
- A validated prediction model for all forms of acute coronary syndrome: estimating the risk of 6-month postdischarge death in an international registry
Kim A Eagle
Department of Internal Medicine, University of Michigan Health System, Ann Arbor, USA
JAMA 291:2727-33. 2004
..Accurate estimation of risk for untoward outcomes after patients have been hospitalized for an acute coronary syndrome (ACS) may help clinicians guide the type and intensity of therapy...
- Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction
Rafael Diaz
Etudios Cardiologica Latin America, Rosario, Argentina
JAMA 298:2399-405. 2007
..While some smaller trials suggest benefit, in the CREATE-ECLA trial, GIK infusion had no effect on 30-day mortality in 20,201 patients...
Access to catheterisation facilities in patients admitted with acute coronary syndrome: multinational registry studyFrans Van de Werf
Universitair Ziekenhuis Gasthuisberg, Herestraat 49, Leuven, Belgium 3000
BMJ 330:441. 2005
..To investigate the relation between access to a cardiac catheterisation laboratory and clinical outcomes in patients admitted to hospital with suspected acute coronary syndrome...
- [C-reactive protein and cardiovascular disease. Basis of scientific evidence]
Wellington Bruno Santos
Universidade Federal Fluminense, Niterio, RJ
Arq Bras Cardiol 80:452-6. 2003
- Impact of in-hospital revascularization on survival in patients with non-ST-elevation acute coronary syndrome and congestive heart failure
Philippe Gabriel Steg
INSERM U 698, Recherche Clinique en Athérothrombose, Universite Paris VII, Centre Hospitalier Bichat Claude Bernard, 46 rue Henri Huchard, 75877 Paris, Cedex 18, France
Circulation 118:1163-71. 2008
..The aims of this study were to describe the use of revascularization in non-ST-elevation acute coronary syndrome and CHF and to analyze its impact on survival...
- Prevention of Heart Failure in Patients in the Heart Outcomes Prevention Evaluation (HOPE) Study
J Malcolm O Arnold
London Health Sciences Centre, London, Canada
Circulation 107:1284-90. 2003
..We assessed an angiotensin-converting enzyme (ACE) inhibitor, ramipril, to prevent the development of heart failure in high-risk patients without known low ejection fraction or heart failure...
- Predictors of hospital mortality in the global registry of acute coronary events
Christopher B Granger
Division of Cardiology, University Medical Center, Durham, NC, USA
Arch Intern Med 163:2345-53. 2003
..CONCLUSIONS: Across the entire spectrum of ACS and in general clinical practice, this model provides excellent ability to assess the risk for death and can be used as a simple nomogram to estimate risk in individual patients...
- Impact of prior peripheral arterial disease and stroke on outcomes of acute coronary syndromes and effect of evidence-based therapies (from the Global Registry of Acute Coronary Events)
Debabrata Mukherjee
Gill Heart Institute and the University of Kentucky, Lexington, Kentucky, USA
Am J Cardiol 100:1-6. 2007
..In conclusion, outcomes after ACS are worse in patients with PAD or stroke, with the highest risk in patients with the 2 conditions and the use of evidence-based therapies are associated with improved outcomes in all ACS subgroups...
- Global patterns of use of antithrombotic and antiplatelet therapies in patients with acute coronary syndromes: insights from the Global Registry of Acute Coronary Events (GRACE)
Andrzej Budaj
Postgraduate Medical School, Grochowski Hospital Warsaw, Poland
Am Heart J 146:999-1006. 2003
..The objective of this report was to describe patterns of use of antithrombotic and antiplatelet therapies in patients with the spectrum of ACS through the use of data from the Global Registry of Acute Coronary Events (GRACE)...
- Adherence to evidence-based therapies after discharge for acute coronary syndromes: an ongoing prospective, observational study
Kim A Eagle
University of Michigan Cardiovascular Center, Ann Arbor, Michigan, USA
Am J Med 117:73-81. 2004
..The reasons for noncompliance are complex, and may be elucidated by future studies of medical and social determinants...
- Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE)
Keith A A Fox
Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh EH16 4SB
BMJ 333:1091. 2006
..To develop a clinical risk prediction tool for estimating the cumulative six month risk of death and death or myocardial infarction to facilitate triage and management of patients with acute coronary syndrome...
- Effect of ramipril on the incidence of diabetes
Jackie Bosch
McMaster University, Hamilton, Canada
N Engl J Med 355:1551-62. 2006
..ClinicalTrials.gov number, NCT00095654 [ClinicalTrials.gov].)...
- Association of peripheral artery disease with treatment and outcomes in acute coronary syndromes. The Global Registry of Acute Coronary Events (GRACE)
James B Froehlich
University of Michigan Health System, Ann Arbor, MI, USA
Am Heart J 151:1123-8. 2006
..Given the poorer hospital outcomes in patients with PAD, our findings suggest considerable opportunity to improve care for these high-risk patients...
- Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial
James J Ferguson
JAMA 292:45-54. 2004
..Enoxaparin is a safe and effective alternative to unfractionated heparin and the advantages of convenience should be balanced with the modest excess of major bleeding...
- Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Salim Yusuf
Population Health Research Institute, Hamilton General Hospital, 237 Barton Street East, Hamilton, Ontario, Canada L8L 2X2
Lancet 364:937-52. 2004
..Therefore, the effect of such factors on risk of coronary heart disease in most regions of the world is unknown...
- Practice variation and missed opportunities for reperfusion in ST-segment-elevation myocardial infarction: findings from the Global Registry of Acute Coronary Events (GRACE)
Kim A Eagle
Division of Cardiology, University Hospital, Ann Arbor, MI 48109 0366, USA
Lancet 359:373-7. 2002
..This study assessed current practices in relation to reperfusion therapy of ST-segment-elevation myocardial infarction from data collected in the multinational, prospective Global Registry of Acute Coronary Events...
