J Roemisch

Summary

Affiliation: Aventis Pharma

Publications

  1. ncbi request reprint The FVII activating protease cleaves single-chain plasminogen activators
    J Romisch
    Aventis Behring GmbH, Research, Marburg, Germany
    Haemostasis 29:292-9. 1999
  2. ncbi request reprint Quantitation of the factor VII- and single-chain plasminogen activator-activating protease in plasmas of healthy subjects
    J Romisch
    Aventis Behring GmbH, Research, Marburg, Germany
    Blood Coagul Fibrinolysis 12:375-83. 2001
  3. ncbi request reprint The frequent Marburg I polymorphism impairs the pro-urokinase activating potency of the factor VII activating protease (FSAP)
    J Roemisch
    Aventis Behring GmbH, Preclinical Research and Development, Marburg, Germany
    Blood Coagul Fibrinolysis 13:433-41. 2002

Collaborators

  • J Romisch
  • A Feussner
  • H A Stöhr
  • H Stohr
  • S Vermöhlen

Detail Information

Publications3

  1. ncbi request reprint The FVII activating protease cleaves single-chain plasminogen activators
    J Romisch
    Aventis Behring GmbH, Research, Marburg, Germany
    Haemostasis 29:292-9. 1999
    ..Whether it plays a physiological role in fibrinolysis deserves further investigation. Its comparatively high affinity to heparin assumes a function in cell surface or matrix events...
  2. ncbi request reprint Quantitation of the factor VII- and single-chain plasminogen activator-activating protease in plasmas of healthy subjects
    J Romisch
    Aventis Behring GmbH, Research, Marburg, Germany
    Blood Coagul Fibrinolysis 12:375-83. 2001
    ..However, factor VII activation was not affected. It is speculated that the FSAP binding site for single-chain plasminogen activators is affected, potentially by as yet unknown polymorphism(s) or mutation(s)...
  3. ncbi request reprint The frequent Marburg I polymorphism impairs the pro-urokinase activating potency of the factor VII activating protease (FSAP)
    J Roemisch
    Aventis Behring GmbH, Preclinical Research and Development, Marburg, Germany
    Blood Coagul Fibrinolysis 13:433-41. 2002
    ..These results support the hypothesis that FSAP contributes to the scuPA-dependent plasma fibrinolytic potential, which can be impaired in plasmas containing the FSAP Marburg I polymorphism, for instance...