Klaus Wolff

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. ncbi request reprint Clinical and histopathological aspects of cutaneous mastocytosis
    K Wolff
    Department of Dermatology, Division of General Dermatology, University of Vienna, Vienna General Hospital, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Leuk Res 25:519-28. 2001
  2. ncbi request reprint Treatment of cutaneous mastocytosis
    Klaus Wolff
    Department of Dermatology, University of Vienna, Austria
    Int Arch Allergy Immunol 127:156-9. 2002
  3. ncbi request reprint Quo vadis dermatology: a scenario for the future
    Klaus Wolff
    Department of Dermatology, University of Vienna, Austria
    J Am Acad Dermatol 48:605-8. 2003
  4. ncbi request reprint Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model
    Christiane Thallinger
    Department of Clinical Pharmacology, Section of Experimental Oncology, University of Vienna, Austria
    J Invest Dermatol 120:1081-6. 2003
  5. ncbi request reprint Expression of FcRn, the MHC class I-related receptor for IgG, in human keratinocytes
    Karla Cauza
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria
    J Invest Dermatol 124:132-9. 2005
  6. ncbi request reprint Thalidomide enhances the anti-tumor activity of standard chemotherapy in a human melanoma xenotransplatation model
    Elisabeth Heere-Ress
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria
    J Invest Dermatol 125:201-6. 2005
  7. ncbi request reprint Validity of an unsupervised self-administered questionnaire for self-assessment of melanoma risk
    Alexandra Harbauer
    Department of Dermatology, Division of General Dermatology, University of Vienna Medical School, Austria
    Melanoma Res 13:537-42. 2003
  8. ncbi request reprint Paraneoplastic pemphigus in association with hepatocellular carcinoma
    Gabriele Hinterhuber
    Department of Dermatology, School of Medicine, University of Vienna, Austria
    J Am Acad Dermatol 49:538-40. 2003
  9. ncbi request reprint Organotypic keratinocyte coculture using normal human serum: an immunomorphological study at light and electron microscopic levels
    Gabriele Hinterhuber
    Department of Dermatology, Division of General Dermatology, University of Vienna Medical School, Vienna, Austria
    Exp Dermatol 11:413-20. 2002
  10. ncbi request reprint Suppression of human melanoma tumor growth in SCID mice by a human high molecular weight-melanoma associated antigen (HMW-MAA) specific monoclonal antibody
    Christine Hafner
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria
    Int J Cancer 114:426-32. 2005

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Clinical and histopathological aspects of cutaneous mastocytosis
    K Wolff
    Department of Dermatology, Division of General Dermatology, University of Vienna, Vienna General Hospital, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Leuk Res 25:519-28. 2001
    ..Leukemia Research 2001;25:603-625.) and thus have a good prognosis. CM of infancy and childhood frequently involutes spontaneously, CM of adults does not. The prevalence of the disease is unknown and familiar occurrence is very rare...
  2. ncbi request reprint Treatment of cutaneous mastocytosis
    Klaus Wolff
    Department of Dermatology, University of Vienna, Austria
    Int Arch Allergy Immunol 127:156-9. 2002
    ....
  3. ncbi request reprint Quo vadis dermatology: a scenario for the future
    Klaus Wolff
    Department of Dermatology, University of Vienna, Austria
    J Am Acad Dermatol 48:605-8. 2003
  4. ncbi request reprint Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model
    Christiane Thallinger
    Department of Clinical Pharmacology, Section of Experimental Oncology, University of Vienna, Austria
    J Invest Dermatol 120:1081-6. 2003
    ....
  5. ncbi request reprint Expression of FcRn, the MHC class I-related receptor for IgG, in human keratinocytes
    Karla Cauza
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria
    J Invest Dermatol 124:132-9. 2005
    ..These findings further emphasize the role of keratinocytes as immunomodulating cells in inflammatory and immunologic processes of the skin...
  6. ncbi request reprint Thalidomide enhances the anti-tumor activity of standard chemotherapy in a human melanoma xenotransplatation model
    Elisabeth Heere-Ress
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria
    J Invest Dermatol 125:201-6. 2005
    ..These data underline the rationale for combining dacarbazine--a cytotoxic agent--and thalidomide--an anti-angiogenic cytostatic agent--as a promising strategy for the treatment of melanoma...
  7. ncbi request reprint Validity of an unsupervised self-administered questionnaire for self-assessment of melanoma risk
    Alexandra Harbauer
    Department of Dermatology, Division of General Dermatology, University of Vienna Medical School, Austria
    Melanoma Res 13:537-42. 2003
    ..The moderate accuracy of self-assessment and physician-assessment to identify individuals at high risk for melanoma is a limitation for the practicability of targeted melanoma screening in general...
  8. ncbi request reprint Paraneoplastic pemphigus in association with hepatocellular carcinoma
    Gabriele Hinterhuber
    Department of Dermatology, School of Medicine, University of Vienna, Austria
    J Am Acad Dermatol 49:538-40. 2003
    ..This patient met all diagnostic criteria for paraneoplastic pemphigus and is, to our knowledge, the first report of a case associated with hepatocellular carcinoma...
  9. ncbi request reprint Organotypic keratinocyte coculture using normal human serum: an immunomorphological study at light and electron microscopic levels
    Gabriele Hinterhuber
    Department of Dermatology, Division of General Dermatology, University of Vienna Medical School, Vienna, Austria
    Exp Dermatol 11:413-20. 2002
    ....
  10. ncbi request reprint Suppression of human melanoma tumor growth in SCID mice by a human high molecular weight-melanoma associated antigen (HMW-MAA) specific monoclonal antibody
    Christine Hafner
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria
    Int J Cancer 114:426-32. 2005
    ..28S. Our results suggest that anti-HMW-MAA mAbs may represent useful reagents to apply passive immunotherapy to patients with malignant melanoma...
  11. ncbi request reprint Pegylated and conventional interferon-alpha induce comparable transcriptional responses and inhibition of tumor growth in a human melanoma SCID mouse xenotransplantation model
    Clemens Krepler
    Department of Dermatology, Division of General Dermatology, University of Vienna, Vienna, Austria
    J Invest Dermatol 123:664-9. 2004
    ..Despite the structural difference between pegylated and conventional IFN-alpha, both agents caused similar transcriptional responses in human melanoma xenotransplants...
  12. ncbi request reprint CpG oligonucleotides elicit antitumor responses in a human melanoma NOD/SCID xenotransplantation model
    Clemens Krepler
    Department of Dermatology, Division of General Dermatology, University of Vienna, Austria
    J Invest Dermatol 122:387-91. 2004
    ..Our findings demonstrate the antitumor activity of oligonucleotides containing immune-stimulatory CpG motifs in a xenotransplantation model with absent B, T cells and a lack of natural killer cell function...
  13. ncbi request reprint IL-3 induces expression of lymphatic markers Prox-1 and podoplanin in human endothelial cells
    Marion Groger
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria
    J Immunol 173:7161-9. 2004
    ..In conclusion, endogenous IL-3 is required to maintain the LEC phenotype in culture, and the addition of IL-3 to BEC appears to induce transdifferentiation of BEC into LEC...
  14. ncbi request reprint PUVA and the international nature of Dr Fitzpatrick's influence
    Klaus Wolff
    Department of Dermatology, University of Vienna, Vienna General Hospital, Vienna, Austria
    J Invest Dermatol 122:xviii-xix. 2004
  15. ncbi request reprint Irwin Freedberg, editor extraordinaire of Fitzpatrick's DIGM
    Klaus Wolff
    Department of Dermatology, Medical University of Vienna, Vienna, Austria
    J Invest Dermatol 126:524-5. 2006
  16. ncbi request reprint Paclitaxel encapsulated in cationic liposomes diminishes tumor angiogenesis and melanoma growth in a "humanized" SCID mouse model
    Rainer Kunstfeld
    Department of Dermatology, Division of General Dermatology, University of Vienna Medical School, Vienna, Austria
    J Invest Dermatol 120:476-82. 2003
    ..In conclusion, we present a model of how to exploit cytotoxic effects of compounds to prevent tumor growth by using cationic liposomes for targeting an antiproliferative drug to blood vessels...
  17. ncbi request reprint RasGAP-like protein IQGAP1 is expressed by human keratinocytes and recognized by autoantibodies in association with bullous skin disease
    Stefan Presslauer
    Department of Dermatology, Division of General Dermatology, University of Vienna, School of Medicine, Vienna, Austria
    J Invest Dermatol 120:365-71. 2003
    ..Furthermore, we found autoantibodies reacting with IQGAP1 in patients with bullous skin eruptions most apparently belonging to the spectrum of bullous pemphigoid...
  18. ncbi request reprint Unusual clinical manifestation of linear IgA dermatosis: a report of two cases
    Karla Cauza
    Division of General Dermatology, Department of Dermatology, University of Vienna, School of Medicine, Austria
    J Am Acad Dermatol 51:S112-7. 2004
    ..The second patient did not respond to dapsone alone and various immunosuppressive treatment regimens. Considerable improvement was achieved with intravenous immunoglobulin therapy combined with corticosteroid and dapsone...
  19. ncbi request reprint Accuracy of computer diagnosis of melanoma: a quantitative meta-analysis
    Barbara Rosado
    Department of Dermatology, University of Vienna Medical School, Vienna, Austria
    Arch Dermatol 139:361-7; discussion 366. 2003
    ..Recent developments in computer technology have raised expectations that fully automated diagnostic instruments will become available to diagnose cutaneous melanoma without the need of human expertise...
  20. ncbi request reprint Epitope-specific antibody response to Mel-CAM induced by mimotope immunization
    Christine Hafner
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria
    J Invest Dermatol 124:125-31. 2005
    ..Our results suggest that mimotopes potentially represent a novel vaccine approach to induce a tumor antigen-specific humoral and cellular response...
  21. ncbi request reprint Bcl-X(L) is a chemoresistance factor in human melanoma cells that can be inhibited by antisense therapy
    Elisabeth Heere-Ress
    Department of Clinical Pharmacology, Section of Experimental Oncology Molecular Pharmacology, University of Vienna, Vienna, Austria
    Int J Cancer 99:29-34. 2002
    ..Reduction of Bcl-x(L) expression by AS oligonucleotides provides a rational and promising approach that may help to overcome chemoresistance in this malignancy...
  22. ncbi request reprint BRAF kinase gene V599E mutation in growing melanocytic lesions
    Robert Loewe
    Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Austria
    J Invest Dermatol 123:733-6. 2004
    ..This raises the question if the V599E mutation determines lesions at risk developing into melanoma and if not, what are the mechanisms controlling growth stop in benign lesions?..
  23. ncbi request reprint The plant lectin wheat germ agglutinin inhibits the binding of pemphigus foliaceus autoantibodies to desmoglein 1 in a majority of patients and prevents pathomechanisms of pemphigus foliaceus in vitro and in vivo
    Susana Ortiz-Urda
    Department of Dermatology, University of Vienna, Vienna, Austria
    J Immunol 171:6244-50. 2003
    ..These findings suggest that WGA may interfere with autoantibody binding to dg1, preventing experimental PF without affecting the adhesive function of dg1. Our observations may provide a new approach to the therapy of PF...
  24. ncbi request reprint Identification of a melanoma marker derived from melanoma-associated endogenous retroviruses
    Johannes Humer
    Department of Dermatology, Division of General Dermatology, Green Hills Biotechnology GmbH, Gersthoferstrasse 29 31, 1180 Vienna, Austria
    Cancer Res 66:1658-63. 2006
    ..The prevalence of anti-MERV antibodies in melanoma patient sera was confirmed by immunofluorescence on env-transfected cells. These data indicate the potential of this candidate peptide as target for diagnosis and immunotherapy...
  25. ncbi request reprint Why is epiluminescence microscopy important?
    Klaus Wolff
    Department of Dermatology, University of Vienna, Vienna General Hospital, Austria
    Recent Results Cancer Res 160:125-32. 2002
    ..ELM and DELM are thus the most important single development of the past three decades in the early diagnosis of melanoma...
  26. ncbi request reprint An endogenous retrovirus derived from human melanoma cells
    Thomas Muster
    Department of Dermatology, Division of General Dermatology, University of Vienna Medical School, Vienna, Austria
    Cancer Res 63:8735-41. 2003
    ..The data suggest that expression of retroviral genes and production of retroviral particles is activated during development of melanoma...
  27. ncbi request reprint Internalization via plasmalemmal vesicles: a route for antidesmoplakin autoantibodies into cultured human keratinocytes
    Karla Cauza
    Department of Dermatology, Division of General Dermatology, University of Vienna, School of Medicine, Vienna, Austria
    Exp Dermatol 12:546-54. 2003
    ..These observations indicate that vesicular transport may represent a relevant biological mechanism for antidesmoplakin autoantibodies to enter keratinocytes and allow access to their corresponding antigenic target in vivo...
  28. pmc Seven novel and stable translocations associated with oncogenic gene expression in malignant melanoma
    Ichiro Okamoto
    Division of General Dermatology, Department of Dermatology, Center of Excellence and the Ludwig Boltzmann Institut for Clinical and Experimental Oncology, Medical University of Vienna, Vienna A 1090, Austria
    Neoplasia 7:303-11. 2005
    ..Because the majority of these breakpoints have been reported previously in MM, our results support the idea of common mechanisms in this disease...
  29. ncbi request reprint Sequence variability of retroviral particles derived from human melanoma cells melanoma-associated retrovirus
    Sonja Hirschl
    Department of Dermatology, Division of General Dermatology, University of Vienna Medical School, Wahringer Gurtel 18 20, Vienna, Austria
    Virus Res 123:211-5. 2007
    ..The particles were found to package sequences, which vary for each of the analyzed cell lines. Moreover, even particles derived from the same cell line contain heterologous sequences...
  30. ncbi request reprint Efficacy and safety of pimecrolimus cream 1% in adult patients with vitiligo: results of a randomized, double-blind, vehicle-controlled study
    Markus Dawid
    Division of General Dermatology, Department of Dermatology, University of Vienna, Vienna General Hospital, Vienna, Austria
    J Dtsch Dermatol Ges 4:942-6. 2006
    ..05%. We performed a double-blind, intrapatient comparison of pimecrolimus cream 1% with placebo cream...
  31. ncbi request reprint Current concepts and review of pimecrolimus in the treatment of psoriasis
    Klaus Wolff
    Department of Dermatology, University of Vienna, Vienna General Hospital, Waehringer Guertel 18 20, Vienna A 1090, Austria
    Dermatol Clin 22:461-5, ix-x. 2004
    ..Although not yet approved, oral pimecrolimus promises to be a novel, highly effective, and well-tolerated drug in the systemic treatment of psoriasis and other T-cell-mediated skin diseases...
  32. ncbi request reprint Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells
    Robert Loewe
    Department of Dermatology, Division of General Dermatology, University of Vienna Medical School, Vienna, Austria
    J Immunol 168:4781-7. 2002
    ..Moreover, DMF does not block NF-kappa B/DNA binding. In conclusion, DMF appears to selectively prevent the nuclear entry of activated NF-kappa B, and this may be the basis of its beneficial effect in psoriasis...
  33. ncbi request reprint RPE65 of retinal pigment epithelium, a putative receptor molecule for plasma retinol-binding protein, is expressed in human keratinocytes
    Gabriele Hinterhuber
    Department of Dermatology, Division of General Dermatology, University of Vienna, School of Medicine, Vienna, Austria
    J Invest Dermatol 122:406-13. 2004
    ....
  34. ncbi request reprint FcgammaRIII expression on cultured human keratinocytes and upregulation by interferon-gamma
    Karla Cauza
    Department of Dermatology, Division of General Dermatology, University of Vienna, School of Medicine, Austria
    J Invest Dermatol 119:1074-9. 2002
    ....
  35. ncbi request reprint Dermoscopy of pigmented skin lesions: results of a consensus meeting via the Internet
    Giuseppe Argenziano
    Department of Dermatology, Second University of Naples, Italy
    J Am Acad Dermatol 48:679-93. 2003
    ..There is a need for better standardization of the dermoscopic terminology in assessing pigmented skin lesions...
  36. ncbi request reprint [Ruptured abdominal aortic aneurysms: status quo after a quarter century of treatment experience]
    Harald Teufelsbauer
    Klinische Abteilung für Gefässchirurgie der Universität Wien, Osterreich
    Wien Klin Wochenschr 115:584-9. 2003
    ..The aim of this analysis was to investigate which patient subgroups benefit from open surgery and in which subgroups a change of treatment strategies should be considered due to lack of improvement despite optimal patient management...
  37. ncbi request reprint [Brief guidelines: squamous cell carcinoma of the skin, lip and eyelids]
    Helmut Breuninger
    Universitäts Hautklinik Tübingen
    J Dtsch Dermatol Ges 4:260-2. 2006
  38. ncbi request reprint Discovery of topical calcineurin inhibitors and pharmacological profile of pimecrolimus
    Anton Stuetz
    Novartis Institutes for Biomedical Research Vienna, Vienna, Austria
    Int Arch Allergy Immunol 141:199-212. 2006
    ..Pimecrolimus cream 1% has proven to be well tolerated, safe, and highly effective in clinical studies in patients with atopic dermatitis...
  39. ncbi request reprint The European Competence Network on Mastocytosis (ECNM)
    Peter Valent
    Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Austria
    Wien Klin Wochenschr 116:647-51. 2004
    ..In addition, the ECNM is dedicated to provide the best available information about the disease to patients and physicians...
  40. ncbi request reprint Borst (Jadassohn): a misnomer
    K Holubar
    Dermatology 209:348; author reply 348. 2004