Research Topics
| P WolfSummaryAffiliation: University of Graz Country: Austria Publications
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Detail Information
Publications
Phenotypic markers, sunlight-related factors and sunscreen use in patients with cutaneous melanoma: an Austrian case-control studyP Wolf
Department of Dermatology, Karl Franzens University, Graz, Austria
Melanoma Res 8:370-8. 1998..However, sunbaths had no protective value when they were associated with sunburns. Although we cannot exclude the presence of an unknown confounding factor, our results suggest that the use of sunscreens does not help prevent melanoma...- Topical treatment with liposomes containing T4 endonuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factor-alphaP Wolf
Department of Dermatology, Karl Franzens University, Graz, Austria
J Invest Dermatol 114:149-56. 2000.... - Increased prevalence of human papillomavirus in hairs plucked from patients with psoriasis treated with psoralen-UV-APeter Wolf
Department of Photodermatology, Karl Franzens University, Graz, Austria
Arch Dermatol 140:317-24. 2004..It has been suggested that PUVA may increase expression of the tumorigenic agent human papillomavirus (HPV) in skin by directly stimulating virus replication, immune suppression, or both, thereby leading to skin cancer formation... - Immune protection factors of chemical sunscreens measured in the local contact hypersensitivity model in humansPeter Wolf
Department of Dermatology, Karl Franzens University, Graz, Austria
J Invest Dermatol 121:1080-7. 2003..2), whereas the sunscreen with broad-spectrum ultraviolet A + B protection exhibited better immunoprotective capacity than predicted from the sun protection factor... - Ultraviolet exposure as the main initiator of p53 mutations in basal cell carcinomas from psoralen and ultraviolet A-treated patients with psoriasisH Seidl
Department of Dermatology and Institute of Pathology, Karl-Franzens University, Graz, Austria
J Invest Dermatol 117:365-70. 2001.... 
Treatment with 311-nm ultraviolet B enhanced response of psoriatic lesions in ustekinumab-treated patients: a randomized intraindividual trialP Wolf
Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Auenbrugger Platz 8, A 8036 Graz, Austria
Br J Dermatol 166:147-53. 2012..e. 75% reduction in Psoriasis Area and Severity Index (PASI) compared with baseline (PASI 75)] in the majority of patients with moderate to severe chronic plaque-type psoriasis...- Efficacy of psoralen plus ultraviolet A therapy vs. biologics in moderate to severe chronic plaque psoriasis: retrospective data analysis of a patient registryM Inzinger
Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Auenbrugger Platz 8, A 8036 Graz, Austria
Br J Dermatol 165:640-5. 2011..Few studies have directly compared the clinical efficacy of psoralen plus ultraviolet A (PUVA) vs. biologics in the treatment of psoriasis... - Extended extracorporeal photochemotherapy with extracorporeal administration of 8-methoxypsoralen in systemic sclerosis. An Austrian single-center studyR R Muellegger
Department of Dermatology, Karl Franzens University School of Medicine, Graz, Austria
Photodermatol Photoimmunol Photomed 16:216-23. 2000..The present study was performed to evaluate the efficacy and safety of extended EXP with extracorporeal application of liquid 8-methoxypsoralen (8-MOP) in the treatment of SSC... - Collision of squamous-cell carcinoma with melanoma in situ in a child with xeroderma pigmentosumA Hofer
Department of Dermatology, Karl Franzens University, Graz, Austria
Dermatology 203:66-9. 2001..To the best of our knowledge, this is the first report of a collision tumor comprising squamous-cell carcinoma and melanoma arising in childhood... - Efficacy of 8-methoxypsoralen vs. 5-methoxypsoralen plus ultraviolet A therapy in patients with mycosis fungoidesA Wackernagel
Photodermatology Unit, Department of Dermatology, Medical University Graz, Austria
Br J Dermatol 154:519-23. 2006..CONCLUSIONS: 5-MOP and 8-MOP have comparable therapeutic efficacy when used in PUVA therapy for MF... - Paired comparison of bathwater versus oral delivery of 8-methoxypsoralen in psoralen plus ultraviolet: A therapy for chronic palmoplantar psoriasisA Hofer
Research Unit of Photodermatology, Medical University Graz, Graz, Austria
Photodermatol Photoimmunol Photomed 22:1-5. 2006..CONCLUSION: This study gives evidence that in the first 4 treatment weeks oral PUVA is slightly more effective than bath PUVA but the former has more systemic side effects... - [Sunscreens. Protection against skin cancers and photoaging]P Wolf
Abteilung für Photodermatologie, Universitätsklinik für Dermatologie und Venerologie, Graz, Austria
Hautarzt 54:839-44. 2003..Because of inadequate data, no definite conclusions can be drawn about the cancer-preventive activity of topical use of sunscreens against basal cell carcinoma and malignant melanoma... - High mutation frequency at Ha-ras exons 1-4 in squamous cell carcinomas from PUVA-treated psoriasis patientsH Kreimer-Erlacher
Department of Dermatology, Karl-Franzens University, Auenbrugger Platz 8, A-8036 Graz, Austria
Photochem Photobiol 74:323-30. 2001.... - The efficacy of excimer laser (308 nm) for vitiligo at different body sitesA Hofer
Medical University of Graz, Department of Dermatology, Graz, Austria
J Eur Acad Dermatol Venereol 20:558-64. 2006..The treatment with XeCl-excimer laser generated 308-nm UVB radiation has shown promising results in patients with vitiligo... - Anaphylaxis to 5-methoxypsoralen during photochemotherapyF J Legat
Department of Dermatology, Karl Franzens University Graz, Auenbruggerplatz 8, A 8036 Graz, Austria
Br J Dermatol 145:821-2. 2001..Anaphylaxis to 5-methoxypsoralen was established by placebo-controlled oral provocation tests... - Randomized double-blinded placebo-controlled intra-individual trial on topical treatment with a 1,25-dihydroxyvitamin D₃ analogue in polymorphic light eruptionA Gruber-Wackernagel
Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Auenbrugger Platz 8, A 8036 Graz, Austria
Br J Dermatol 165:152-63. 2011..Similar to UV radiation, calcitriol (1,25-dihydroxyvitamin D₃) and its analogues such as calcipotriol have been shown to exhibit immunosuppressive properties... - Long-term results in the treatment of vitiligo with oral khellin plus UVAA Hofer
Department of Dermatology, University of Graz, Auenbruggerplatz 8, A 8036, Graz, Austria
Eur J Dermatol 11:225-9. 2001..These data indicate that KUVA seems to be safe as well as effective for vitiligo, provided treatment is administered long enough... - Optimal weekly frequency of 308-nm excimer laser treatment in vitiligo patientsA Hofer
Department of Photodermatology, Medical University Graz, Auenbruggerplatz 8, A-8036 Graz, Austria
Br J Dermatol 152:981-5. 2005..However, treatment periods of more than 12 weeks may be necessary to obtain a satisfactory clinical repigmentation, particularly when vitiligo lesions are treated only 1 x or 2 x compared with 3 x weekly... - Primary cutaneous follicle center cell lymphoma with follicular growth patternL Cerroni
Department of Dermatology, University of Graz, Austria
Blood 95:3922-8. 2000..7 months). Our study demonstrates that primary cutaneous follicular lymphoma represents a distinct entity of the cutaneous B-cell lymphomas. (Blood. 2000;95:3922-3928).. - Accidental bullous phototoxic reactions to bergamot aromatherapy oilS Kaddu
Department of Dermatology, University of Graz, Austria
J Am Acad Dermatol 45:458-61. 2001..This report highlights the potential health hazard related to the increasing use of psoralen-containing aromatherapy oils... - Photodamage to the cutaneous sensory nerves: role in photoaging and carcinogenesis of the skin?Franz J Legat
Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, A 8036, Graz, Austria
Photochem Photobiol Sci 5:170-6. 2006..In addition, we discuss the possible role of these mediators in photocarcinogenesis... - The angiotensin-converting enzyme insertion/deletion and the endothelin -134 3A/4A gene polymorphisms in patients with chronic plaque psoriasisWolfgang Weger
Department of Dermatology, Medical University of Graz, Austria
Exp Dermatol 16:993-8. 2007..The purpose of the present study was thus to investigate a hypothesized association between these gene polymorphisms and the presence of chronic plaque psoriasis... 
Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosisPeter Wolf
Research Unit for Photodermatology, Department of Dermatology, Medical University Graz, Auenbrugger Platz 8, A 8036 Graz, Austria
Am J Pathol 169:795-805. 2006....- Measurement of sunscreen immune protection factors in humans: a consensus paperAnny Fourtanier
, Clichy, France
J Invest Dermatol 125:403-9. 2005..There is a need for a new simpler method of IPF that will have to be validated against existing models... - Nonmonoclonal PTCH gene mutations in psoralen plus UVA-associated basal cell carcinomasEllen Heitzer
J Invest Dermatol 128:746-9. 2008 - Specific cutaneous infiltrates of B-cell chronic lymphocytic leukemia (B-CLL) at sites typical for Borrelia burgdorferi infectionLorenzo Cerroni
Department of Dermatology, University of Graz, Austria
J Cutan Pathol 29:142-7. 2002..Specific skin manifestations of B-CLL can also be observed at sites typical for lymphadenosis benigna cutis (nipple, scrotum, earlobe), a Borrelia burgdorferi-associated cutaneous B-cell pseudolymphoma... - The ultraviolet fingerprint dominates the mutational spectrum of the p53 and Ha-ras genes in psoralen + ultraviolet A keratoses from psoriasis patientsPeter Wolf
Department of Photodermatology, Karl Franzens University, Graz, Austria
J Invest Dermatol 122:190-200. 2004.... - High frequency of ultraviolet mutations at the INK4a-ARF locus in squamous cell carcinomas from psoralen-plus-ultraviolet-A-treated psoriasis patientsHeidemarie Kreimer-Erlacher
Department of Dermatology, Karl-Franzens University, Graz, Austria
J Invest Dermatol 120:676-82. 2003.... - No detection of human herpesvirus 8 in different types of cutaneous angiosarcomaRegina Fink-Puches
Arch Dermatol 138:131-2. 2002 - Narrowband UV-B phototherapy, alefacept, and clearance of psoriasisFranz J Legat
Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, A 8036 Graz, Austria
Arch Dermatol 143:1016-22. 2007..To determine whether the addition of 311-nm narrowband UV-B (NB UV-B) phototherapy accelerates and improves the therapeutic efficacy of alefacept, a biological antipsoriatic drug approved for the treatment of moderate to severe psoriasis... - Clusterin associates with altered elastic fibers in human photoaged skin and prevents elastin from ultraviolet-induced aggregation in vitroElke Janig
Institute of Pathology, Medical University of Graz, Graz, Austria
Am J Pathol 171:1474-82. 2007..The interaction of both proteins was further analyzed by electron microscopy, size exclusion chromatography, and mass spectrometry, in which clusterin was found in a stable complex with elastin after UV exposure... - Five-year follow-up of a randomized, prospective trial of topical methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinomaLesley E Rhodes
Photobiology Unit, Department of Dermatology, University of Manchester, Salford Royal Foundation Hospital, Manchester M6 8HD, England
Arch Dermatol 143:1131-6. 2007..To compare 5-year lesion recurrence rates in primary nodular basal cell carcinoma treated with topical methyl aminolevulinate photodynamic therapy (PDT) or simple excision surgery... - p14ARF hypermethylation is common but INK4a-ARF locus or p53 mutations are rare in Merkel cell carcinomaAnita Lassacher
Research Unit for Photodermatology, Medical University of Graz, Graz, Austria
J Invest Dermatol 128:1788-96. 2008..Together, these findings suggest that p14ARF silencing may be an important mechanism in MCC tumorigenesis, and thus a potential target for therapeutic intervention in this highly aggressive tumor type... - Topical methyl aminolevulinate photodynamic therapy for the treatment of folliculitisMichael Horn
Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Graz, Austria
Photodermatol Photoimmunol Photomed 23:145-7. 2007..The folliculitis had occurred in areas of acne-prone skin of the patients, mainly after long-term administration of antibiotics... - Lichen aureus: clinicopathologic features, natural history, and relationship to mycosis fungoidesRegina Fink-Puches
Department of Dermatology, Medical University of Graz, Graz, Austria
Arch Dermatol 144:1169-73. 2008..There was no relationship between the presence or absence of monoclonality and patient status at follow-up assessments. Conclusion Patients with classic lesions of LA do not show progression to MF... - Role of the interleukin 15 96516A>T and IL15 96330C>A gene polymorphisms in Caucasian patients with chronic plaque psoriasisWolfgang Weger
J Dermatol Sci 51:147-9. 2008 - Absence status epilepticus: the first documented case?Peter Wolf
Danish Epilepsy Centre, Dianalund, Denmark
Epilepsia 48:4-5. 2007 - UV fingerprints predominate in the PTCH mutation spectra of basal cell carcinomas independent of clinical phenotypeEllen Heitzer
Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Graz, Austria
J Invest Dermatol 127:2872-81. 2007.... - UV light-induced linear IgA dermatosisWolfgang Salmhofer
Department of Dermatology, University of Graz, Austria
J Am Acad Dermatol 50:109-15. 2004..We conclude that linear IgA dermatosis should be added to the list of autoimmune bullous diseases induced and/or aggravated by UV radiation... - Photodynamic therapy using topical methyl aminolevulinate vs surgery for nodular basal cell carcinoma: results of a multicenter randomized prospective trialLesley E Rhodes
Department of Dermatology, Royal Liverpool University Hospital, Liverpool, England
Arch Dermatol 140:17-23. 2004..CONCLUSIONS: Methyl aminolevulinate PDT is an effective treatment for nodular BCC, and while there is a trend for higher recurrence with this modality, it conveys the advantage over surgery of better cosmesis... - The role of calcitonin gene-related peptide in cutaneous immunosuppression induced by repeated subinflammatory ultraviolet irradiation exposureFranz J Legat
Department of Dermatology, Emory University, School of Medicine, Atlanta, GA, USA
Exp Dermatol 13:242-50. 2004..These findings support a role for CGRP in the local immunosuppression caused by chronic, repeated subinflammatory UV exposure... - CDKN2A and MC1R mutations in patients with sporadic multiple primary melanomaKetty Peris
J Invest Dermatol 122:1327-30. 2004 - Langerhans cell resistance, CD11b+ cell influx, and cytokine mRNA expression in skin after UV exposure in patients with polymorphous light eruption as compared with healthy control subjectsAlexandra Wackernagel
J Invest Dermatol 122:1342-4. 2004 - Sunburn cell formation, dendritic cell migration, and immunomodulatory factor production after solar-simulated irradiation of sunscreen-treated human skin explants in vitroRainer Hofmann-Wellenhof
Department of Dermatology, Medical University of Graz, Graz, Austria
J Invest Dermatol 123:781-7. 2004..We conclude that our model may be useful in determining the immunoprotective capacity of sunscreens... - Reduction of treatment frequency and UVA dose does not substantially compromise the antipsoriatic effect of oral psoralen-UVAFranz J Legat
Division of Photodermatology, Department of Dermatology, Medical University Graz Austria
J Am Acad Dermatol 51:746-54. 2004..5 MPD twice/wk) than for the more intensive regimens. CONCLUSIONS: Reducing treatment frequency and UVA dose does not substantially compromise the therapeutic efficacy of PUVA... - T1799A BRAF mutation is common in PUVA lentiginesAnita Lassacher
J Invest Dermatol 126:1915-7. 2006 - Comparison of topical methyl aminolevulinate photodynamic therapy with cryotherapy or Fluorouracil for treatment of squamous cell carcinoma in situ: Results of a multicenter randomized trialColin Morton
Forth Valley Dermatology Centre, Stirling Royal Infirmary, Stirling, Scotland
Arch Dermatol 142:729-35. 2006..CONCLUSION: Methyl aminolevulinate PDT is an effective treatment option for squamous cell carcinoma in situ, with excellent cosmesis... - Psoralen plus UVA vs. UVB-311 nm for the treatment of lichen planusAlexandra Wackernagel
Research Unit for Photodermatology, Medical University Graz, Graz, Austria
Photodermatol Photoimmunol Photomed 23:15-9. 2007..The purpose of this study was to evaluate and compare the short- and long-term therapeutic efficacy of psoralen plus UVA (PUVA) vs. UVB-311 nm in the treatment of patients with disseminated lichen planus... - Repeated subinflammatory ultraviolet B irradiation increases substance P and calcitonin gene-related peptide content and augments mustard oil-induced neurogenic inflammation in the skin of ratsFranz J Legat
Department of Dermatology, Karl Franzens University Graz Medical School, Auenbruggerplatz 8, 8036 Graz, Austria
Neurosci Lett 329:309-13. 2002..These data suggest that repeated subinflammatory UVB irradiation locally increases the content of cutaneous SP and CGRP by an increase of neuropeptide content of nerve fibers rather than by an increase of overall nerve fiber density...