- Organism size promotes the evolution of specialized cells in multicellular digital organismsM Willensdorfer
Program for Evolutionary Dynamics, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
J Evol Biol 21:104-10. 2008..This demonstrates that the evolution of simple multicellular organisms which are composed of many functionally identical cells accelerates the evolution of more complex organisms with specialized cells...
- Phenotypic mutation rates and the abundance of abnormal proteins in yeastMartin Willensdorfer
Program for Evolutionary Dynamics, Harvard University, Cambridge, Massachusetts, United States of America
PLoS Comput Biol 3:e203. 2007..Our work allows us to estimate the phenotypic mutation rate based on data on the fraction of abnormal proteins. For S. cerevisiae, we predict that the value for the phenotypic mutation rate is between 2 x 10(-4) and 6 x 10(-4)...
- On the evolution of differentiated multicellularityMartin Willensdorfer
Program for Evolutionary Dynamics, Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Evolution 63:306-23. 2009..I discuss the biology of primitive multicellular organisms with respect to the model predictions. I find a good agreement and outline how this work can be used to guide further quantitative studies of multicellularity...