Research Topics
Genomes and GenesSpecies | Andreas TomaschitzSummaryAffiliation: University of Vienna Country: Austria Publications
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Publications
Circulating aldosterone and mortality in female nursing home residentsAndreas Tomaschitz
Department of Cardiology, Medical University of Graz, Graz, Austria
Exp Gerontol 48:313-8. 2013..We therefore aimed to assess the relationship between circulating aldosterone levels and mortality in a population-based cohort study of female nursing home residents...
Effect of eplerenone on parathyroid hormone levels in patients with primary hyperparathyroidism: a randomized, double-blind, placebo-controlled trialAndreas Tomaschitz
Department of Cardiology, Medical University of Graz, Auenbruggerplatz 15, Graz, 8036, Austria
BMC Endocr Disord 12:19. 2012..abstract:..
Circulating dopamine and C-peptide levels in fasting nondiabetic hypertensive patients: the Graz Endocrine Causes of Hypertension studyAndreas Tomaschitz
Department of Internal Medicine, Division of Cardiology, Medical University of Graz, Graz, Austria
Diabetes Care 35:1771-3. 2012..We examined the association between circulating dopamine and C-peptide concentrations using data from the Graz Endocrine Causes of Hypertension (GECOH) study...
Aldosterone and parathyroid hormone: a precarious couple for cardiovascular diseaseAndreas Tomaschitz
Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
Cardiovasc Res 94:10-9. 2012..In view of the reciprocal interaction between aldosterone and PTH and the potentially ensuing CV damage, studies are urgently needed to evaluate diagnostic and therapeutic strategies addressing the interaction between the two hormones...
Relationship between plasma aldosterone concentration and soluble cellular adhesion molecules in patients referred to coronary angiographyA Tomaschitz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria
Exp Clin Endocrinol Diabetes 119:649-55. 2011..Little is known, however, regarding an association between circulating aldosterone levels and soluble cellular adhesion molecules in humans...
Aldosterone to renin ratio--a reliable screening tool for primary aldosteronism?A Tomaschitz
Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Graz, Austria
Horm Metab Res 42:382-91. 2010..This review also provides an overview about the physiology of the renin-angiotensin-aldosterone system, highlights current laboratory methods for aldosterone and renin determination, and addresses potential influence factors on the ARR...
Associations of plasma renin with 10-year cardiovascular mortality, sudden cardiac death, and death due to heart failureAndreas Tomaschitz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Auenbruggerplatz 15, A 8036 Graz, Austria
Eur Heart J 32:2642-9. 2011..This study in a large cohort of patients sought to evaluate the association between plasma renin concentration (PRC) and cardiovascular mortality after long-term follow-up of almost 10 years...
Association of plasma aldosterone with cardiovascular mortality in patients with low estimated GFR: the Ludwigshafen Risk and Cardiovascular Health (LURIC) StudyAndreas Tomaschitz
Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical University of Graz, Austria
Am J Kidney Dis 57:403-14. 2011..We hypothesized that level of kidney function might modify the association between plasma aldosterone level and CVD mortality...
Aldosterone and arterial hypertensionAndreas Tomaschitz
Division of Endocrinology and Nuclear Medicine, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
Nat Rev Endocrinol 6:83-93. 2010....
Independent association between 1,25-dihydroxyvitamin D, 25-hydroxyvitamin D and the renin-angiotensin system: The Ludwigshafen Risk and Cardiovascular Health (LURIC) studyAndreas Tomaschitz
Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical University of Graz, Austria
Clin Chim Acta 411:1354-60. 2010..Antihypertensive and tissue-protective properties of vitamin D metabolites are increasingly attributed to the inhibition of renin synthesis by 1,25-dihydroxyvitamin D [1,25(OH)2D] in the kidney...
Low homoarginine concentration is a novel risk factor for heart diseaseStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria
Heart 97:1222-7. 2011..Homoarginine is an amino acid which may play a role in nitric oxide and energy metabolism. Low homoarginine concentrations have previously been linked to increased mortality, but the underlying mechanisms remain unknown...
Hyperparathyroidism in patients with primary aldosteronism: cross-sectional and interventional data from the GECOH studyStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
J Clin Endocrinol Metab 97:E75-9. 2012..Experimental studies suggest that aldosterone induces hypercalciuria and might contribute to hyperparathyroidism...
Aldosterone/renin ratio determines peripheral and central blood pressure values over a broad rangeAndreas Tomaschitz
Division of Endocrinology and Nuclear Medicine, Department of Internal Medicine, Medical University of Graz, Graz, Austria
J Am Coll Cardiol 55:2171-80. 2010....
Low 25-hydroxyvitamin D is associated with increased mortality in female nursing home residentsStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
J Clin Endocrinol Metab 97:E653-7. 2012..Whether low 25-hydroxyvitamin D (25[OH]D) concentrations are an independent risk factor for mortality in these patients is, however, unclear...
Vitamin D status and mortality in chronic kidney diseaseStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria
Nephrol Dial Transplant 26:3603-9. 2011..73 m(2). Whether low 25(OH)D levels in these patients are associated with higher mortality is unclear. This issue was addressed in the present work...
Vitamin D status and arterial hypertension: a systematic reviewStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Austria
Nat Rev Cardiol 6:621-30. 2009....
Vitamin D and cardiovascular disease: update and outlookStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria
Scand J Clin Lab Invest Suppl 243:83-91. 2012..It should, however, be noted that justification for the prevention and treatment of vitamin D deficiency comes from evidence based benefits of vitamin D supplementation on musculoskeletal health...
Vitamin D, cardiovascular disease and mortalityStefan Pilz
Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical University of Graz, Graz, Austria
Clin Endocrinol (Oxf) 75:575-84. 2011..In current clinical practice, the overall risks and costs of vitamin D supplementation should be weighed against the potential adverse consequences of untreated vitamin D deficiency...
Plasma aldosterone levels are associated with increased cardiovascular mortality: the Ludwigshafen Risk and Cardiovascular Health (LURIC) studyAndreas Tomaschitz
Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Graz, Austria
Eur Heart J 31:1237-47. 2010..With the present analysis, we aimed at evaluating prospectively whether plasma aldosterone correlates with all-cause and CV disease (CVD) mortality in a large cohort of patients...
Parathyroid hormone level is associated with mortality and cardiovascular events in patients undergoing coronary angiographyStefan Pilz
Division of Endocrinology and Nuclear Medicine, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
Eur Heart J 31:1591-8. 2010..We aimed to elucidate whether PTH levels are associated with mortality and fatal cardiovascular events in patients referred for coronary angiography...
Low serum homoarginine is a novel risk factor for fatal strokes in patients undergoing coronary angiographyStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Austria, Auenbruggerplatz 15, 8036 Graz, Austria
Stroke 42:1132-4. 2011..We aimed to investigate whether homoarginine levels are also associated with fatal strokes and a history of nonfatal cerebrovascular disease...
Vitamin D deficiency and myocardial diseasesStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Graz, Austria
Mol Nutr Food Res 54:1103-13. 2010..In our opinion, the current knowledge of the beneficial effects of vitamin D on myocardial and overall health strongly argue for vitamin D supplementation in all vitamin D-deficient patients with or at high risk for myocardial diseases...
Cinacalcet hydrochloride for the treatment of hyperparathyroidismNicolas Verheyen
Medical University of Graz, Department of Cardiology, Auenbruggerplatz 15, 8036 Graz, Austria
Expert Opin Pharmacother 14:793-806. 2013....
Vitamin D supplementation and regulatory T cells in apparently healthy subjects: vitamin D treatment for autoimmune diseases?Barbara Prietl
Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Austria
Isr Med Assoc J 12:136-9. 2010..Epidemiological data show significant associations of vitamin D deficiency and autoimmune diseases. Vitamin D may prevent autoimmunity by stimulating naturally occurring regulatory T cells...
Epidemiology of vitamin D insufficiency and cancer mortalityStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Graz, Austria
Anticancer Res 29:3699-704. 2009....
Sclerostin and its association with physical activity, age, gender, body composition, and bone mineral content in healthy adultsKarin Amrein
Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, A 8036 Graz, Austria
J Clin Endocrinol Metab 97:148-54. 2012..Sclerostin is produced by osteocytes and inhibits bone formation through the Wnt/β-catenin-signaling pathway. Only limited data are available on circulating sclerostin levels in healthy subjects...
Role of vitamin D in arterial hypertensionStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Austria
Expert Rev Cardiovasc Ther 8:1599-608. 2010..Therefore, we recommend that testing for and treating vitamin D deficiency in patients with arterial hypertension should be seriously considered...
Vitamin D supplementation: a promising approach for the prevention and treatment of strokesStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Austria
Curr Drug Targets 12:88-96. 2011....
Graz Endocrine Causes of Hypertension (GECOH) study: a diagnostic accuracy study of aldosterone to active renin ratio in screening for primary aldosteronismStefan Pilz
Department of Internal Medicine, Division of Endocrinology and Nuclear Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
BMC Endocr Disord 9:11. 2009..CONCLUSION: Screening for PA with subsequent targeted treatment is of great potential benefit for hypertensive patients. In the GECOH study we will evaluate a standardised procedure for screening and diagnosing of this disease...
Associations of Sun Exposure with 25-Hydroxyvitamin D and Parathyroid Hormone Levels in a Cohort of Hypertensive Patients: The Graz Endocrine Causes of Hypertension (GECOH) StudyStefan Pilz
Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria
Int J Endocrinol 2012:732636. 2012..Translation of these findings into recommendations for the prevention and treatment of vitamin D deficiency remains a challenge for the future...
