Oksana Tehlivets

Summary

Affiliation: University of Graz
Country: Austria

Publications

  1. pmc S-adenosyl-L-homocysteine hydrolase and methylation disorders: yeast as a model system
    Oksana Tehlivets
    Institute of Molecular Biosciences, University of Graz, Graz, Austria
    Biochim Biophys Acta 1832:204-15. 2013
  2. pmc S-adenosyl-L-homocysteine hydrolase, key enzyme of methylation metabolism, regulates phosphatidylcholine synthesis and triacylglycerol homeostasis in yeast: implications for homocysteine as a risk factor of atherosclerosis
    Nermina Malanovic
    Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50 II, Graz, Austria
    J Biol Chem 283:23989-99. 2008
  3. ncbi request reprint Fatty acid synthesis and elongation in yeast
    Oksana Tehlivets
    Institute of Molecular Biosciences, University of Graz, A8010 Graz, Austria
    Biochim Biophys Acta 1771:255-70. 2007
  4. ncbi request reprint S-adenosyl-L-homocysteine hydrolase in yeast: key enzyme of methylation metabolism and coordinated regulation with phospholipid synthesis
    Oksana Tehlivets
    Institute of Molecular Biosciences, SFB Biomembrane Research Center, University of Graz, Schubertstrasse 1, 8010 Graz, Austria
    FEBS Lett 577:501-6. 2004

Collaborators

  • Sepp D Kohlwein
  • Nermina Malanovic
  • Gerald Rechberger
  • Heimo Wolinski
  • Ingo Streith

Detail Information

Publications4

  1. pmc S-adenosyl-L-homocysteine hydrolase and methylation disorders: yeast as a model system
    Oksana Tehlivets
    Institute of Molecular Biosciences, University of Graz, Graz, Austria
    Biochim Biophys Acta 1832:204-15. 2013
    ..Inhibition of S-adenosyl-L-homocysteine hydrolase is also linked to antiviral effects. In this review the advantages of yeast as an experimental system to understand pathologies associated with AdoHcy accumulation will be discussed...
  2. pmc S-adenosyl-L-homocysteine hydrolase, key enzyme of methylation metabolism, regulates phosphatidylcholine synthesis and triacylglycerol homeostasis in yeast: implications for homocysteine as a risk factor of atherosclerosis
    Nermina Malanovic
    Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50 II, Graz, Austria
    J Biol Chem 283:23989-99. 2008
    ..The addition of homocysteine, by the reversal of the Sah1-catalyzed reaction, also leads to TG accumulation in yeast, providing an attractive model for the role of homocysteine as a risk factor of atherosclerosis in humans...
  3. ncbi request reprint Fatty acid synthesis and elongation in yeast
    Oksana Tehlivets
    Institute of Molecular Biosciences, University of Graz, A8010 Graz, Austria
    Biochim Biophys Acta 1771:255-70. 2007
    ..In this review, we summarize what is currently known about enzymes involved in cellular fatty acid synthesis and elongation, and discuss potential links between fatty acid metabolism, physiology and cellular regulation...
  4. ncbi request reprint S-adenosyl-L-homocysteine hydrolase in yeast: key enzyme of methylation metabolism and coordinated regulation with phospholipid synthesis
    Oksana Tehlivets
    Institute of Molecular Biosciences, SFB Biomembrane Research Center, University of Graz, Schubertstrasse 1, 8010 Graz, Austria
    FEBS Lett 577:501-6. 2004
    ..Profound changes in cellular lipid composition upon depletion of Sah1p support the notion of a tight interaction between lipid metabolism and Sah1p function...