H Sinzinger

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. ncbi Side effects of statins--prevalence, relevance, consequences
    Helmut Sinzinger
    Wien Klin Wochenschr 114:887-8. 2002
  2. ncbi The economy class syndrome--a survey of 19 cases
    H Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group Vienna, Austria
    Vasa 28:199-203. 1999
  3. ncbi Isoprostane 8-epi-PGF2alpha is frequently increased in patients with muscle pain and/or CK-elevation after HMG-Co-enzyme-A-reductase inhibitor therapy
    H Sinzinger
    Department of Nuclear Medicine, University of Vienna, Austria
    J Clin Pharm Ther 26:303-10. 2001
  4. ncbi Oxidation injury in patients receiving HMG-CoA reductase inhibitors: occurrence in patients without enzyme elevation or myopathy
    Helmut Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group ASF, Vienna, Austria
    Drug Saf 25:877-83. 2002
  5. ncbi Prostaglandins and lipid modification
    G Sobal
    Department of Nuclear Medicine, University of Vienna, Vienna, Austria
    Curr Pharm Des 7:461-74. 2001
  6. ncbi Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications"
    H Sinzinger
    Department of Nuclear Medicine, University of Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 67:309-10. 2002
  7. ncbi Muscular side effects of statins
    Helmut Sinzinger
    Department of Nuclear Medicine, University of Vienna, A 1090 Vienna, Austria
    J Cardiovasc Pharmacol 40:163-71. 2002
  8. ncbi [Unaltered homocysteine levels during simvastatin therapy]
    H Sinzinger
    Wilhelm Auerswald Atheroskleroseforschungsgruppe ASF Wien
    Wien Klin Wochenschr 112:540-3. 2000
  9. ncbi Eicosanoid production and lymphatic responsiveness in human cigarette smokers compared with non-smokers
    H Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group Vienna, Austria
    Lymphology 33:24-31. 2000
  10. ncbi [Imaging of early carotid artery atherosclerotic lesions with 111In-labeled polyelonalhuman IgG (HIG)]
    H Kritz
    Universitätsklinik für Nuklearmedizin, Wien, Osterreich
    Nuklearmedizin 36:270-5. 1997

Collaborators

Detail Information

Publications67

  1. ncbi Side effects of statins--prevalence, relevance, consequences
    Helmut Sinzinger
    Wien Klin Wochenschr 114:887-8. 2002
  2. ncbi The economy class syndrome--a survey of 19 cases
    H Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group Vienna, Austria
    Vasa 28:199-203. 1999
    ..Systematic data on haemostatic parameters in these patients are not available yet...
  3. ncbi Isoprostane 8-epi-PGF2alpha is frequently increased in patients with muscle pain and/or CK-elevation after HMG-Co-enzyme-A-reductase inhibitor therapy
    H Sinzinger
    Department of Nuclear Medicine, University of Vienna, Austria
    J Clin Pharm Ther 26:303-10. 2001
    ..Muscle pains with or without CK-elevation are among the most frequently observed side-effects in patients with hyperlipoproteinemia on various statins. The pathophysiological background, however, remains obscure...
  4. ncbi Oxidation injury in patients receiving HMG-CoA reductase inhibitors: occurrence in patients without enzyme elevation or myopathy
    Helmut Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group ASF, Vienna, Austria
    Drug Saf 25:877-83. 2002
    ..Several lines of evidence indicate that even mild forms of myopathy during statin treatment may be associated with in vivo oxidation injury. In contrast, statin therapy has been shown to be associated with a decrease in oxidation injury...
  5. ncbi Prostaglandins and lipid modification
    G Sobal
    Department of Nuclear Medicine, University of Vienna, Vienna, Austria
    Curr Pharm Des 7:461-74. 2001
    ..The influence of various eicosanoids on lipoprotein modification, however, has not been assessed yet...
  6. ncbi Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications"
    H Sinzinger
    Department of Nuclear Medicine, University of Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 67:309-10. 2002
  7. ncbi Muscular side effects of statins
    Helmut Sinzinger
    Department of Nuclear Medicine, University of Vienna, A 1090 Vienna, Austria
    J Cardiovasc Pharmacol 40:163-71. 2002
    ..Much more research should be directed onto the pathophysiological (genetic?) background to finally evaluate possible therapeutic consequences rather than simply to withdraw or change the respective statin...
  8. ncbi [Unaltered homocysteine levels during simvastatin therapy]
    H Sinzinger
    Wilhelm Auerswald Atheroskleroseforschungsgruppe ASF Wien
    Wien Klin Wochenschr 112:540-3. 2000
    ..These findings indicate that in contrast to a number of other lipid lowering agents, simvastatin does not affect plasma homocysteine levels...
  9. ncbi Eicosanoid production and lymphatic responsiveness in human cigarette smokers compared with non-smokers
    H Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group Vienna, Austria
    Lymphology 33:24-31. 2000
    ....
  10. ncbi [Imaging of early carotid artery atherosclerotic lesions with 111In-labeled polyelonalhuman IgG (HIG)]
    H Kritz
    Universitätsklinik für Nuklearmedizin, Wien, Osterreich
    Nuklearmedizin 36:270-5. 1997
    ..To assess the value of scintigraphy with 111In-HIG for diagnosis and evaluation of the stage and the clinical extent of carotid artery disease in humans a prospective clinical comparative trial of scintigraphy vs. sonography was performed...
  11. ncbi Increase of isoprostane 8-epi-PGF(2alpha)after restarting smoking
    F Chehne
    Department of Nuclear Medicine, University of Vienna, A-1090 Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 64:307-10. 2001
    ..These data indicate a fast response of restarting as on quitting smoking on in vivo oxidation injury. The oxidation injury reflected by 8-epi-PGF(2alpha)may be a key pathogenetic mechanism in smoking-induced vascular injury...
  12. ncbi The isoprostane, 8-epi-PGF2 alpha, is accumulated in coronary arteries isolated from patients with coronary heart disease
    M R Mehrabi
    Department of Cardiology, University of Vienna, Austria
    Cardiovasc Res 43:492-9. 1999
    ....
  13. ncbi Regular ingestion of opuntia robusta lowers oxidation injury
    A Budinsky
    Clinical Division of Oncology, University of Vienna, A-1090 Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 65:45-50. 2001
    ..This traditional food of the American Indians thus may have a significant cardiovascular benefit...
  14. ncbi The isoprostane 8-epi-PGF(2alpha) is a valuable indicator of oxidative injury in human heart valves
    M R Mehrabi
    Department of Cardiology, University of Vienna, Wahringer Gurtel 18 20, Postfach 120, A 1097, Vienna, Austria
    Cardiovasc Pathol 10:241-5. 2001
    ..30+/-58.77 pg/mg protein in aortic valves, P=.09). Considering the data presented in this study, we suggest that 8-epi-PGF(2alpha) is a valuable indicator of oxidative injury in human semilunar valves...
  15. ncbi Accumulation of oxidized LDL in human semilunar valves correlates with coronary atherosclerosis
    M R Mehrabi
    Department of Cardiology, University of Vienna, Austria
    Cardiovasc Res 45:874-82. 2000
    ....
  16. ncbi Scintigraphic evaluation of functional hepatic mass in patients with advanced breast cancer
    I Virgolini
    Department of Nuclear Medicine, University of Vienna, Austria
    Br J Cancer 68:549-54. 1993
    ....
  17. ncbi 6-oxo-PGF(1 alpha)and 8-epi-PGF(2 alpha)in the arterial wall layers of various species: a comparison between intact and atherosclerotic areas
    A Oguogho
    Department of Nuclear Medicine, University of Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 64:167-71. 2001
    ..These findings are providing an information on the extent of oxidation injury at various sites of different types of atherosclerotic process...
  18. ncbi Effects of isradipine on platelet function in hypertension at rest and during exercise
    P Fitscha
    Department of Internal Medicine II, Policlinic, Vienna, Austria
    Am J Hypertens 4:178S-180S. 1991
    ..It is concluded that treatment of hypertension with a compound that lowers blood pressure and inhibits platelet activation may be of clinical benefit when routinely applied in hypertensive patients...
  19. ncbi Effect of giving up cigarette smoking and restarting in patients with clinically manifested atherosclerosis
    F Chehne
    Department of Nuclear Medicine, University of Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 67:333-9. 2002
    ..These findings indicate that the in vivo oxidation injury associated with cigarette smoking quickly decreases after quitting but increases soon after restarting immediately...
  20. ncbi Platelet function after single [153Sm]EDTMP therapy in prostate cancer
    K Weiss
    Department of Nuclear Medicine, Hospital Wr. Neustadt, Austria
    Q J Nucl Med Mol Imaging 50:330-3. 2006
    ..CONCLUSIONS: We conclude that a single dose of 1.1 GBq 153Sm-EDTMP does not significantly affect in vivo and ex vivo platelet function...
  21. ncbi Modification of low-density lipoprotein during radiolabeling with 99mTc using three labeling methods
    G Sobal
    Department of Nuclear Medicine, Medical University of Vienna, Vienna, Austria
    Q J Nucl Med Mol Imaging 50:334-43. 2006
    ..The influence of the LDL sampling methods, isolation, preparation and radiolabeling of lipoproteins on structure modification and the subsequent imaging behavior has as yet not been addressed in detail...
  22. ncbi In vitro adsorption of 99Tc(m)-MIBI, 99Tc(m)-tetrofosmin, 99Tc(m)-furifosmin and 99Tc(m)O4- onto tubes
    M Rodrigues
    Department of Nuclear Medicine, University Hospital, Vienna, Austria
    Nucl Med Commun 22:105-10. 2001
    ..Our findings indicate that systematic investigations to evaluate the adsorption of radiopharmaceuticals onto materials used during in vitro studies of cellular uptake should be considered a mandatory aspect of quality control...
  23. ncbi The influence of isoprostanes on ADP-induced platelet aggregation and cyclic AMP-generation in human platelets
    N Leitinger
    Department of Nuclear Medicine, University of Vienna, Austria
    Thromb Res 86:337-42. 1997
    ..In this study we investigate possible pro- or antiaggregatory properties of various F- and E-type isoprostanes on human platelets...
  24. ncbi Verapamil decreases accumulation of 99Tcm-MIBI and 99Tcm-tetrofosmin in human breast cancer and soft tissue sarcoma cell lines
    M Rodrigues
    Department of Nuclear Medicine, University Hospital, Vienna, Austria
    Nucl Med Commun 22:645-50. 2001
    ..Our data indicate that verapamil is not a promising agent for increasing the sensitivity of scintigraphy with 99Tcm-MIBI or 99Tcm-tetrofosmin, or for evaluating Pgp tumour status in these types of tumours...
  25. ncbi Effects of PGI2 and analogues (taprostene, iloprost) on oxidation of native and glycated LDL
    G Sobal
    Department of Nuclear Medicine, University of Vienna, Austria
    Life Sci 65:1237-46. 1999
    ....
  26. ncbi (Iso) Prostaglandins in saliva indicate oxidation injury after radioiodine therapy
    R M Wolfram
    Departments of Angiology, University of Vienna, Austria
    Rev Esp Med Nucl 23:183-8. 2004
    ..CONCLUSION: These results clearly demonstrate a dose- and time-dependent tissue (TXB2, 6-oxo-PGF1alpha) and oxidation in-jury (8-epi-PGF2alpha) after 131I-therapy in the salivary glands...
  27. ncbi Daily prickly pear consumption improves platelet function
    R Wolfram
    Department of Angiology, University of Vienna, Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 69:61-6. 2003
    ..No sex difference was seen. Prickly pear may induce at least part of its beneficial actions on the cardiovascular system via decreasing platelet activity and thereby improving haemostatic balance...
  28. ncbi Calcium antagonists as inhibitors of in vitro low density lipoprotein oxidation and glycation
    G Sobal
    Department of Nuclear Medicine, University of Vienna, Vienna, Austria
    Biochem Pharmacol 61:373-9. 2001
    ..Thus CA, like other antioxidants, significantly retard AGE formation, while initial glycation reactions, such as Amadori product formation, are only weakly inhibited...
  29. ncbi Assessment of peripheral arterial vascular disease with radionuclide techniques
    R M Wolfram
    Department of Nuclear Medicine, University of Vienna, Austria
    Semin Nucl Med 31:129-42. 2001
    ..A great deal of work is still required to transform in vitro and experimental experience into more meaningful routine radioisotopic investigations in patients with PVD...
  30. ncbi Effects of Hydergine on platelet deposition on "active" human carotid artery lesions and platelet function
    G Steurer
    2nd Department of Internal Medicine, University of Vienna, Austria
    Thromb Res 55:577-89. 1989
    ..Co-dergocrine may thereby be of benefit in prevention of mural thrombus formation and prevention of transient ischemic attacks, but also of atherosclerosis in man...
  31. ncbi The Vienna protocol and perspectives in radionuclide therapy
    H Sinzinger
    Department of Nuclear Medicine, Medical University of Vienna, Vienna, Austria
    Q J Nucl Med Mol Imaging 55:420-30. 2011
    ..Further research should be directed to identify underlying mechanisms of response and predictors of benefit and to elaborate an improved therapeutic schedule for further enhancing the response rate...
  32. ncbi Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers
    R M Wolfram
    Department of Angiology, University of Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 66:529-33. 2002
    ..These data show that regular daily black tea consumption for 1 month improves platelet function and decreases thromboxane and 8-epi-PGF(2 alpha) to a varying extent indicating a reduced in vivo oxidation injury...
  33. ncbi 8-Epi-PGF2alpha and 6-oxo-PGF1alpha in human (varicose) veins: influence of age, sex, and risk factors
    Susan Meghdadi
    Department of Nuclear Medicine, University of Vienna, Vienna, Austria
    Angiology 54:317-24. 2003
    ..Lower 8-epi-PGF2alpha in varicose veins may shift the venous tone toward vasodilatation and contribute to development and progression of varicosis...
  34. ncbi Isoprostane 8-epi-prostaglandin F2 alpha is a potent contractor of human peripheral lymphatics
    H Sinzinger
    Department of Nuclear Medicine, University of Vienna, Austria
    Lymphology 30:155-9. 1997
    ..Other isoprostanes (8-epi-PGE1, 8-epi-PGE2) had only limited lymphatic contractile potency. These data suggest a potentially relevant role for epi-8-PGF2 alpha in facilitating lymph transport especially in conditions of inflammation...
  35. ncbi Do human platelets express COX-2?
    R Reiter
    Department of Nuclear Medicine, University of Vienna, Währinger Gürtel 19 20, A 1090 Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 64:299-305. 2001
    ..As the amount of COX-2 in platelets might be below the detection limit of the methods used, the biological relevance COX-2 in platelets, if even existing at low amounts, remains to be established...
  36. ncbi Influence of drugs on myocardial iodine-123 metaiodobenzylguanidine uptake in rabbit myocardium
    S Mayer
    Department of Nuclear Medicine, University of Vienna, Austria
    Eur J Nucl Med 27:340-5. 2000
    ..Further studies with uptake-II-blocking substances as well as with isolated myocardial cells will be needed to clarify the nature of the myocardial MIBG uptake mechanism...
  37. ncbi Modification of low-density lipoprotein by different radioiodination methods
    G Sobal
    Department of Nuclear Medicine, University of Vienna, Austria
    Nucl Med Biol 31:381-8. 2004
    ..Once modified, LDL no longer reflects the native molecule, exhibiting altered functional properties. Using radiolabeled LDL this fact should be considered...
  38. ncbi Prevalence and relevance of thyroid dysfunction in 1922 cholesterol screening participants
    C Pirich
    Department of Nuclear Medicine, University Hospital of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    J Clin Epidemiol 53:623-9. 2000
    ..These results argue against indiscriminate measurements of TSH concentrations in clinically healthy subjects either with normocholesterolemia or hypercholesterolemia...
  39. ncbi Methylene blue-enhanced stability of (99mTc)HMPAO and simplified quality control--a comparative investigation
    G Sobal
    Department of Nuclear Medicine, University of Vienna, Austria
    Appl Radiat Isot 54:633-6. 2001
    ..The octanol extraction method, using higher extraction volume (up to 3 ml), is recommended as a fast and efficient approach for the quality control in daily clinical routine...
  40. ncbi [Radiation doses deriving from patients treated with (166)Ho-ferric hydroxide]
    J Preitfellner
    Universitätsklinik für Nuklearmedizin, AKH Wien, Wahringer Gurtel 18 20, A 1090 Wien, Osterreich
    Nuklearmedizin 42:251-4. 2003
    ..To estimate radiation doses deriving from patients treated with (166)Ho ferric hydroxide...
  41. ncbi 99m-Tc-tetrofosmin scintigraphy for the evaluation of suspicious palpable and non-palpable breast lesions
    R Obwegeser
    Department of Obstetrics and Gynecology, University Hospital Vienna, Austria
    Breast Cancer Res Treat 62:253-8. 2000
    ..To assess the value of 99m-Tc-tetrofosmin (tetrofosmin) scintigraphy in patients with palpable and nonpalpable breast lesions...
  42. ncbi Lymphatic mapping of sentinel nodes in early vulvar cancer
    G Sliutz
    Department of Gynecology, University of Vienna, Vienna, A 1090, Austria
    Gynecol Oncol 84:449-52. 2002
    ..The aim of the study was to determine the diagnostic accuracy and feasibility of sentinel lymph node (SLN) detection using a gamma probe in patients suffering from vulvar cancer...
  43. ncbi Professional athletes suffering from familial hypercholesterolaemia rarely tolerate statin treatment because of muscular problems
    H Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group ASF Vienna, Institute for Diagnosis and Treatment of Atherosclerosis and Lipid Disorders ATHOS, Vienna, Austria
    Br J Clin Pharmacol 57:525-8. 2004
    ..Muscular problems are the major group of side-effects during statin treatment. They are known to occur much more frequently during and after exercise...
  44. ncbi Troglitazone inhibits long-term glycation and oxidation of low-density lipoprotein
    Grazyna Sobal
    Department of Nuclear Medicine, Medical University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    J Cardiovasc Pharmacol 46:672-80. 2005
    ..T may be used as a model to explore the thiazolidinediones' mechanism on oxidation in a more general aspect for treatment for T2DM, because T is not clinically available...
  45. ncbi Binding of [99mTc]chondroitin sulfate to scavenger receptors on human chondrocytes as compared to binding of oxidized [125I]LDL on human macrophages
    G Sobal
    Department of Nuclear Medicine, Radiopharmacology Unit, University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    J Recept Signal Transduct Res 22:459-70. 2002
    ..3 x 10(6) using LPS-activated monocytes. These data are comparable to the binding affinity found for lipoprotein-proteoglycan-complexes and hence are an indication but not a proof that CD36 is involved in CS binding to human chondrocytes...
  46. ncbi Radiation exposure from patients treated with 165Dy-ferric hydroxide
    E Havlik
    Department of Biomedical Engineering and Physics, University of Vienna, Austria
    Nucl Med Commun 22:79-82. 2001
    ..Our results clearly demonstrate that the calculated radiation exposure to personnel and family members is well below the maximum annual dose limit for non-professionally exposed persons...
  47. ncbi Decrease of prostaglandin I2 binding sites in thyroid cancer
    I Virgolini
    2nd Department of Nuclear Medicine, Ludwig Boltzmann Institute for Nuclear Medicine, University of Vienna, Austria
    Br J Cancer 58:584-8. 1988
    ..6 +/- 25.1 fmol mg-1 membrane protein (Kd: 54.6 +/- 16.7 nM). Well differentiated papillar and follicular cancers did not differ from each other.(ABSTRACT TRUNCATED AT 250 WORDS)..
  48. ncbi Decreased hepatic function in patients with hepatoma or liver metastasis monitored by a hepatocyte specific galactosylated radioligand
    I Virgolini
    Second Department of Nuclear Medicine, University of Vienna, Austria
    Br J Cancer 61:937-41. 1990
    ..It is concluded that determination of HBP density in vivo via a specific tracer is a new, simple and reliable approach for the determination of remaining hepatic function in patients with primary or secondary liver cancer...
  49. ncbi Homocysteine--a pathophysiological cornerstone in obstetrical and gynaecological disorders?
    R Obwegeser
    Department of Obstetrics and Gynecology, University Hospital, Vienna, Austria
    Hum Reprod Update 5:64-72. 1999
    ..We suggest that elevated concentrations of homocysteine could be a marker and perhaps a cause of, or contributive to, a wide range of obstetrical and gynaecological disorders...
  50. ncbi Radionuclide vascular imaging and characterization of human metabolic endothelial surface lining
    H Sinzinger
    Department of Nuclear Medicine, University of Vienna, Vienna, Austria
    Q J Nucl Med Mol Imaging 50:226-35. 2006
    ..Stem cell research is the next upcoming approach to give nuclear medicine a chance to demonstrate its clinical value in a rapidly developing new discipline...
  51. ncbi Should lidocaine be avoided for local anesthesia in radiation synovectomy?
    I Schweeger
    Department of Nuclear Medicine, University of Vienna, Vienna, Austria
    Q J Nucl Med Mol Imaging 48:207-10. 2004
    ..This study was performed to uncover any unfavourable effect of lidocaine on stability of (166)Ho-FHMA (ferrum hydroxide macroaggregate)...
  52. ncbi Enhanced accumulation of the isoprostane, 8-epi-PGF2 alpha, in human aortic and pulmonary valves of patients with coronary heart disease
    M R Mehrabi
    Department of Cardiology, University of Vienna, Wahringer Gurtel 18 20, Postfach 120, A 1097 Vienna, Austria
    Histol Histopathol 17:1053-9. 2002
    ..Considering the data presented in this study, we suggest that 8-epi-PGF2 alpha is a valuable indicator of oxidative injury in human semilunar valves...
  53. ncbi Salivary isoprostanes indicate increased oxidation injury in periodontitis with additional tobacco abuse
    Roswitha M Wolfram
    Department of Angiology, Medical University of Vienna, Austria
    Biofactors 28:21-31. 2006
    ..The results of this study indicate that: 1) salivary IPs can reliably assess the degree of oxidative stress, and: 2) smoking and periodontal disease are two modifiable cardiovascular risk factors, able to potentiate each other...
  54. ncbi Narghile (water pipe) smoking influences platelet function and (iso-)eicosanoids
    Roswitha M Wolfram
    Department of Angiology, University of Vienna, Austria
    Life Sci 74:47-53. 2003
    ..These findings indicate a significant increase of in vivo oxidative stress by regular water pipe smoking...
  55. ncbi Variable influence of statins on isoprostanes in hyperlipidemia
    Helmut Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group, Vienna, Austria
    Adv Exp Med Biol 525:209-12. 2003
  56. ncbi Zinc as antiperoxidative agent following iodine-131 induced changes on the antioxidant system and the morphology of red blood cells
    Hossein Ahmadzadehfar
    Hell J Nucl Med 10:35; author reply 35-6. 2007
  57. ncbi Radioiodine therapy induces dose-dependent in vivo oxidation injury: evidence by increased isoprostane 8-epi-PGF(2 alpha)
    Roswitha M Wolfram
    Department of Angiology, University of Vienna, Vienna, Austria
    J Nucl Med 43:1254-8. 2002
    ..CONCLUSION: These findings document a significant, dose-dependent in vivo oxidation injury as a consequence of therapeutic radioiodine application to the salivary gland...
  58. ncbi Reduction of oxidative stress and modulation of autoantibodies against modified low-density lipoprotein after rosuvastatin therapy
    Ulrike Resch
    Medical University of Vienna, Wilhelm Auerswald Atherosclerosis Research Group, Vienna, Austria
    Br J Clin Pharmacol 61:262-74. 2006
    ..To examine the effect of 24 weeks' rosuvastatin treatment on oxidative stress and changes in immune response to oxidized low-density lipoprotein (LDL)...
  59. ncbi Increased isoprostanes in children of smoking parents
    Helmut Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group, Vienna, Austria
    Adv Exp Med Biol 525:213-5. 2003
  60. ncbi Passive cigarette smoking increases isoprostane formation
    Hossein Ahmadzadehfar
    Wilhelm Auerswald Atherosclerosis Research Group (ASF) Vienna, Austria
    Life Sci 78:894-7. 2006
    ..The findings document a significant temporary increase in in vivo oxidation injury due to passive smoke favouring development and/or progression of vascular disease...
  61. ncbi Effect of simvastatin on the oxidation of native and modified lipoproteins
    Grazyna Sobal
    Department of Nuclear Medicine, Medical University of Vienna, Austria
    Biochem Pharmacol 70:1185-91. 2005
    ..0 and 2.3, respectively, but no changes in the presence of simvastatin were observed. These data show that simvastatin besides its lipid-lowering action has also significant antioxidative properties...
  62. ncbi Enhanced oxidative stress in coronary heart disease and chronic heart failure as indicated by an increased 8-epi-PGF(2alpha)
    Roswitha Wolfram
    Department of Angiology, Medical University of Vienna, Vienna, Austria
    Eur J Heart Fail 7:167-72. 2005
    ....
  63. ncbi Raloxifene does not prevent fibrinogen oxidation in vitro
    Margit Blasbichler
    Institute for Diagnosis and Treatment of Atherosclerosis and Lipid Disorders (ATHOS, Vienna, Austria
    Med Sci Monit 11:PI1-4. 2005
    ..CONCLUSIONS: Our data suggest that raloxifene, in contrast to its effect on LDL, lacks the capability to inhibit the oxidation of fibrinogen. The biological relevance of this finding still needs to be assessed in vivo...
  64. ncbi Comments on Elevated urinary 8-isoprostaglandin F2 alpha in females with Graves' hyperthyroidism: K.M. Kim, K.-J. Paéng, J.R. Hahm, D.R. Kim, B.C. Chung. Prostagl. Leukotr. and Essent. Fatty Acids 71 (2004) 143-147
    Hossein Ahmadzadehfar
    Wilhelm Auerswald Atherosclerosis Research Group (ASF) Vienna, Nadlergasse 1, 1090 Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 71:409-10. 2004
  65. ncbi Defects in the prostaglandin system--what is known?
    Rosemarie A Reiter
    Department of Clinical Pharmacology, University of Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 71:347-50. 2004
    ..All interested people are invited to join...
  66. ncbi Statin-induced myositis migrans
    Helmut Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group ASF, Institute for Diagnosis and Treatment of Lipid Disorders and Atherosclerosis ATHOS, Vienna, Austria
    Wien Klin Wochenschr 114:943-4. 2002
    ..The clinical consequence (to withdraw the drug or not) of these milder statin side effects are discussed...
  67. ncbi Flu-like response on statins
    Helmut Sinzinger
    Wilhelm Auerswald Atherosclerosis Research Group ASF, Vienna, Austria
    Med Sci Monit 8:CR384-8. 2002
    ..We are reporting on a so far unknown flu-like response on statins with very severe symptoms of exhaustion, weakness, aching muscles and joints elevated acute phase response markers and sometimes even subfebrile body temperature...