Stefan Schwaiger

Summary

Affiliation: University of Innsbruck
Country: Austria

Publications

  1. pmc 2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells
    Angela Ladurner
    Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    Biochem Pharmacol 84:804-12. 2012
  2. pmc Identification and pharmacological characterization of the anti-inflammatory principal of the leaves of dwarf elder (Sambucus ebulus L.)
    Stefan Schwaiger
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Josef Moeller Haus, Innrain 52c, A 6020 Innsbruck, Austria
    J Ethnopharmacol 133:704-9. 2011
  3. doi request reprint Iridoid glycosides from the leaves of Sambucus ebulus
    Valerio Pieri
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Josef Moeller Haus, Innrain 52c, 6020 Innsbruck, Austria
    J Nat Prod 72:1798-803. 2009
  4. pmc A new bisabolane derivative of Leontopodium andersonii
    Stefan Schwaiger
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Center of Molecular Biosciences Innsbruck, A 6020 Innsbruck, Austria
    Nat Prod Commun 5:667-8. 2010
  5. pmc Metabolic fingerprinting of Leontopodium species (Asteraceae) by means of ¹H NMR and HPLC-ESI-MS
    Stefan Safer
    Institute of Pharmacy Pharmacognosy, Faculty of Chemistry and Pharmacy, Center for Molecular Biosciences Innsbruck CMBI, University of Innsbruck, A 6020 Innsbruck, Austria
    Phytochemistry 72:1379-89. 2011
  6. doi request reprint Chemical profiling of Edelweiss (Leontopodium alpinum Cass.) extracts by micellar electrokinetic capillary chromatography
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, CCB, Innrain 80 82, 6020 Innsbruck, Austria
    Fitoterapia 83:1680-6. 2012
  7. pmc Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts
    Ute Reisinger
    Cardiac Surgery Research Laboratory, Department of Cardiac Surgery, Innsbruck Medical University, Innrain 66, A 6020 Innsbruck, Austria
    Cardiovasc Res 82:542-9. 2009
  8. pmc In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens
    Judith M Rollinger
    Institute of Pharmacy, Pharmacognosy, and Center for Molecular Biosciences, University of Innsbruck, 6020 Innsbruck, Austria
    Planta Med 75:195-204. 2009
  9. doi request reprint Development of a fast and convenient method for the isolation of triterpene saponins from Actaea racemosa by high-speed countercurrent chromatography coupled with evaporative light scattering detection
    Serhat Sezai Cicek
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Innsbruck, Austria
    Planta Med 76:467-73. 2010
  10. pmc Extracts and constituents of Leontopodium alpinum enhance cholinergic transmission: brain ACh increasing and memory improving properties
    Ariane Hornick
    Institute of Pharmacy, Pharmacology and Toxicology, University of Innsbruck, A 6020 Innsbruck, Austria
    Biochem Pharmacol 76:236-48. 2008

Collaborators

Detail Information

Publications17

  1. pmc 2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells
    Angela Ladurner
    Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    Biochem Pharmacol 84:804-12. 2012
    ..DPPB enhances eNOS activity and endothelial NO release by raising intracellular Ca(2+) levels and increases signaling through a CaMKKβ-AMPK dependent pathway...
  2. pmc Identification and pharmacological characterization of the anti-inflammatory principal of the leaves of dwarf elder (Sambucus ebulus L.)
    Stefan Schwaiger
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Josef Moeller Haus, Innrain 52c, A 6020 Innsbruck, Austria
    J Ethnopharmacol 133:704-9. 2011
    ..dwarf elder) in order to rationalize the traditional use of this plant for the treatment of chronically inflammatory diseases...
  3. doi request reprint Iridoid glycosides from the leaves of Sambucus ebulus
    Valerio Pieri
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Josef Moeller Haus, Innrain 52c, 6020 Innsbruck, Austria
    J Nat Prod 72:1798-803. 2009
    ..Compounds 1-4 represent the first examples of acylated iridoid diglycosides bearing the uncommon D-ribohexo-3-ulopyranosyl sugar moiety. Compound 6 is the first iridoid glycoside with a 2-deoxy-D-glucopyranosyl sugar moiety...
  4. pmc A new bisabolane derivative of Leontopodium andersonii
    Stefan Schwaiger
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Center of Molecular Biosciences Innsbruck, A 6020 Innsbruck, Austria
    Nat Prod Commun 5:667-8. 2010
    ....
  5. pmc Metabolic fingerprinting of Leontopodium species (Asteraceae) by means of ¹H NMR and HPLC-ESI-MS
    Stefan Safer
    Institute of Pharmacy Pharmacognosy, Faculty of Chemistry and Pharmacy, Center for Molecular Biosciences Innsbruck CMBI, University of Innsbruck, A 6020 Innsbruck, Austria
    Phytochemistry 72:1379-89. 2011
    ..Furthermore, Leontopodium dedekensii and L. sinense, two closely related species in terms of morphology and DNA-fingerprints, could be distinguished clearly using ¹H NMR and LC-MS metabolic fingerprinting...
  6. doi request reprint Chemical profiling of Edelweiss (Leontopodium alpinum Cass.) extracts by micellar electrokinetic capillary chromatography
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, CCB, Innrain 80 82, 6020 Innsbruck, Austria
    Fitoterapia 83:1680-6. 2012
    ..25-0.34%, caffeic acids: 4.99-6.21%, leontopodic acid: 4.21-5.05%)...
  7. pmc Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts
    Ute Reisinger
    Cardiac Surgery Research Laboratory, Department of Cardiac Surgery, Innsbruck Medical University, Innrain 66, A 6020 Innsbruck, Austria
    Cardiovasc Res 82:542-9. 2009
    ....
  8. pmc In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens
    Judith M Rollinger
    Institute of Pharmacy, Pharmacognosy, and Center for Molecular Biosciences, University of Innsbruck, 6020 Innsbruck, Austria
    Planta Med 75:195-204. 2009
    ..GRAVEOLENS on three different proteins has shown promise as an IN SILICO tool for rational target fishing and pharmacological profiling of extracts and single chemical entities in natural product research...
  9. doi request reprint Development of a fast and convenient method for the isolation of triterpene saponins from Actaea racemosa by high-speed countercurrent chromatography coupled with evaporative light scattering detection
    Serhat Sezai Cicek
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Innsbruck, Austria
    Planta Med 76:467-73. 2010
    ..9 mg). Purity of the isolated substances was 96.8 %, 96.2 %, 97.9 %, and 98.4 %, respectively. The same method was suitable for the purification of actein and 23-epi-26-deoxyactein, with purities of 97.0 % and 98.3 %...
  10. pmc Extracts and constituents of Leontopodium alpinum enhance cholinergic transmission: brain ACh increasing and memory improving properties
    Ariane Hornick
    Institute of Pharmacy, Pharmacology and Toxicology, University of Innsbruck, A 6020 Innsbruck, Austria
    Biochem Pharmacol 76:236-48. 2008
    ..Taken together, isocomene and related constituents of L. alpinum deserve further interest as potential antidementia agents in brain diseases associated with cholinergic deficits...
  11. pmc Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro
    Lisa Baumgartner
    Institute of Pharmacy Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Josef Moeller Haus, Innrain 52c, 6020 Innsbruck, Austria
    J Nat Prod 74:1779-86. 2011
    ..The present findings not only support the ethnopharmacological use of K. lappacea roots but also reveal that the isolated lignan derivatives contribute strongly to the anti-inflammatory activity of this herbal drug...
  12. pmc Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2,3-dioxygenase
    Susanne Kuehnl
    University of Innsbruck, Institute of Pharmacy Pharmacognosy and Center for Molecular Biosciences Innsbruck CMBI, 6020 Innsbruck, Austria
    Phytomedicine 20:1190-5. 2013
    ..The in vitro results support the view that some of the anti-inflammatory, anticancer and antidepressant properties of C. tinctorius lignans might relate to their suppressive influence on tryptophan breakdown. ..
  13. pmc Quantitative analysis of anti-inflammatory lignan derivatives in Ratanhiae radix and its tincture by HPLC-PDA and HPLC-MS
    Lisa Baumgartner
    Institute of Pharmacy Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    J Pharm Biomed Anal 56:546-52. 2011
    ..49-0.71% and 0.51-0.53% in the roots and 0.66-0.68 mg/ml and 0.70-0.71 mg/ml in the commercial tinctures, respectively...
  14. pmc Cotinus coggygria wood: novel flavanone dimer and development of an HPLC/UV/MS method for the simultaneous determination of fourteen phenolic constituents
    Diana S Antal
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Innsbruck, Austria
    Planta Med 76:1765-72. 2010
    ..The new natural compound C-3/C-3'' flavanone dimer occurred in concentrations of 0.03-0.06%; the two latter compounds could represent valuable markers for the identification and quality control of C. coggygria wood...
  15. ncbi request reprint Quantitative analysis of iridoids, secoiridoids, xanthones and xanthone glycosides in Gentiana lutea L. roots by RP-HPLC and LC-MS
    Anita Aberham
    Institute of Pharmacy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    J Pharm Biomed Anal 45:437-42. 2007
    ..46-9.53%), followed by loganic acid (0.10-0.76%), swertiamarin (0.21-0.45%) and the xanthone glycosides. Gentisin and isogentisin were found in much lower concentrations between 0.02 and 0.11%, respectively...
  16. ncbi request reprint Antibacterial activity of Leontopodium alpinum (Edelweiss)
    Michael J Dobner
    Institut fur Pharmazie, Abteilung Pharmakognosie, Leopold Franzens Universitat Innsbruck, A 6020 Innsbruck, Austria
    J Ethnopharmacol 89:301-3. 2003
    ..These results support the ethnomedicinal use of Leontopodium alpinum for the treatment of respiratory and abdominal disorders...
  17. doi request reprint Characterization of an UV- and VIS-absorbing, purpurogallin-derived secondary pigment new to algae and highly abundant in Mesotaenium berggrenii (Zygnematophyceae, Chlorophyta), an extremophyte living on glaciers
    Daniel Remias
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Innsbruck, Austria
    FEMS Microbiol Ecol 79:638-48. 2012
    ..Sequencing of the 18S rRNA gene of this alpine species and of its arctic relative, the filamentous Ancylonema nordenskiöldii, underlined their distinct taxonomic position within the Zygnematophyceae...