Research Topics
| Stefan SchwaigerSummaryAffiliation: University of Innsbruck Country: Austria Publications
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Detail Information
Publications
Identification and pharmacological characterization of the anti-inflammatory principal of the leaves of dwarf elder (Sambucus ebulus L.)Stefan Schwaiger
Institute of Pharmacy Pharmacognosy, University of Innsbruck, Josef Moeller Haus, Innrain 52c, A 6020 Innsbruck, Austria
J Ethnopharmacol 133:704-9. 2011..dwarf elder) in order to rationalize the traditional use of this plant for the treatment of chronically inflammatory diseases...
Iridoid glycosides from the leaves of Sambucus ebulusValerio Pieri
Institute of Pharmacy Pharmacognosy, University of Innsbruck, Josef Moeller Haus, Innrain 52c, 6020 Innsbruck, Austria
J Nat Prod 72:1798-803. 2009..Compounds 1-4 represent the first examples of acylated iridoid diglycosides bearing the uncommon D-ribohexo-3-ulopyranosyl sugar moiety. Compound 6 is the first iridoid glycoside with a 2-deoxy-D-glucopyranosyl sugar moiety...
Metabolic fingerprinting of Leontopodium species (Asteraceae) by means of ¹H NMR and HPLC-ESI-MSStefan Safer
Institute of Pharmacy Pharmacognosy, Faculty of Chemistry and Pharmacy, Center for Molecular Biosciences Innsbruck CMBI, University of Innsbruck, A 6020 Innsbruck, Austria
Phytochemistry 72:1379-89. 2011..Furthermore, Leontopodium dedekensii and L. sinense, two closely related species in terms of morphology and DNA-fingerprints, could be distinguished clearly using ¹H NMR and LC-MS metabolic fingerprinting...
A new bisabolane derivative of Leontopodium andersoniiStefan Schwaiger
Institute of Pharmacy Pharmacognosy, University of Innsbruck, Center of Molecular Biosciences Innsbruck, A 6020 Innsbruck, Austria
Nat Prod Commun 5:667-8. 2010....
Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass graftsUte Reisinger
Cardiac Surgery Research Laboratory, Department of Cardiac Surgery, Innsbruck Medical University, Innrain 66, A 6020 Innsbruck, Austria
Cardiovasc Res 82:542-9. 2009....
Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitroLisa Baumgartner
Institute of Pharmacy Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Josef Moeller Haus, Innrain 52c, 6020 Innsbruck, Austria
J Nat Prod 74:1779-86. 2011..The present findings not only support the ethnopharmacological use of K. lappacea roots but also reveal that the isolated lignan derivatives contribute strongly to the anti-inflammatory activity of this herbal drug...
Quantitative analysis of anti-inflammatory lignan derivatives in Ratanhiae radix and its tincture by HPLC-PDA and HPLC-MSLisa Baumgartner
Institute of Pharmacy Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
J Pharm Biomed Anal 56:546-52. 2011..49-0.71% and 0.51-0.53% in the roots and 0.66-0.68 mg/ml and 0.70-0.71 mg/ml in the commercial tinctures, respectively...
Development of a fast and convenient method for the isolation of triterpene saponins from Actaea racemosa by high-speed countercurrent chromatography coupled with evaporative light scattering detectionSerhat Sezai Cicek
Institute of Pharmacy Pharmacognosy, University of Innsbruck, Innsbruck, Austria
Planta Med 76:467-73. 2010..9 mg). Purity of the isolated substances was 96.8 %, 96.2 %, 97.9 %, and 98.4 %, respectively. The same method was suitable for the purification of actein and 23-epi-26-deoxyactein, with purities of 97.0 % and 98.3 %...
In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolensJudith M Rollinger
Institute of Pharmacy, Pharmacognosy, and Center for Molecular Biosciences, University of Innsbruck, 6020 Innsbruck, Austria
Planta Med 75:195-204. 2009..GRAVEOLENS on three different proteins has shown promise as an IN SILICO tool for rational target fishing and pharmacological profiling of extracts and single chemical entities in natural product research...
Cotinus coggygria wood: novel flavanone dimer and development of an HPLC/UV/MS method for the simultaneous determination of fourteen phenolic constituentsDiana S Antal
Institute of Pharmacy Pharmacognosy, University of Innsbruck, Innsbruck, Austria
Planta Med 76:1765-72. 2010..The new natural compound C-3/C-3'' flavanone dimer occurred in concentrations of 0.03-0.06%; the two latter compounds could represent valuable markers for the identification and quality control of C. coggygria wood...
Chemical profiling of Edelweiss (Leontopodium alpinum Cass.) extracts by micellar electrokinetic capillary chromatographyMarkus Ganzera
Institute of Pharmacy, Pharmacognosy, University of Innsbruck, CCB, Innrain 80 82, 6020 Innsbruck, Austria
Fitoterapia 83:1680-6. 2012..25-0.34%, caffeic acids: 4.99-6.21%, leontopodic acid: 4.21-5.05%)...
Characterization of an UV- and VIS-absorbing, purpurogallin-derived secondary pigment new to algae and highly abundant in Mesotaenium berggrenii (Zygnematophyceae, Chlorophyta), an extremophyte living on glaciersDaniel Remias
Institute of Pharmacy Pharmacognosy, University of Innsbruck, Innsbruck, Austria
FEMS Microbiol Ecol 79:638-48. 2012..Sequencing of the 18S rRNA gene of this alpine species and of its arctic relative, the filamentous Ancylonema nordenskiöldii, underlined their distinct taxonomic position within the Zygnematophyceae...
Extracts and constituents of Leontopodium alpinum enhance cholinergic transmission: brain ACh increasing and memory improving propertiesAriane Hornick
Institute of Pharmacy, Pharmacology and Toxicology, University of Innsbruck, A 6020 Innsbruck, Austria
Biochem Pharmacol 76:236-48. 2008..Taken together, isocomene and related constituents of L. alpinum deserve further interest as potential antidementia agents in brain diseases associated with cholinergic deficits...
