Christian Schlotterer

Summary

Affiliation: University of Veterinary Medicine
Country: Austria

Publications

  1. ncbi request reprint Genetics. Where do male genes live?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Science 299:670-1. 2003
  2. pmc Nonrandom Wolbachia infection status of Drosophila melanogaster strains with different mtDNA haplotypes
    Maria D S Nunes
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, Vienna, Austria
    Mol Biol Evol 25:2493-8. 2008
  3. pmc Gene expression analysis indicates extensive genotype-specific crosstalk between the conjugative F-plasmid and the E. coli chromosome
    Bettina Harr
    Institut fur Genetik, Universitat Koln, Zuelpicher Strasse 47, 50674 Koln, Germany
    BMC Microbiol 6:80. 2006
  4. pmc Survey of microsatellite clustering in eight fully sequenced species sheds light on the origin of compound microsatellites
    Robert Kofler
    University of Natural Resources and Applied Life Sciences, Department for Agrobiotechnology IFA Tulln, Institute of Biotechnology in Plant Production, Tulln, Austria
    BMC Genomics 9:612. 2008
  5. pmc PanGEA: identification of allele specific gene expression using the 454 technology
    Robert Kofler
    University of Natural Resources and Applied Life Sciences, Department for Agrobiotechnology, Institute for Plant Production Biotechnology Konrad Lorenz Str 20, A 3430 Tulln, Austria
    BMC Bioinformatics 10:143. 2009
  6. ncbi request reprint High mutation rate of a long microsatellite allele in Drosophila melanogaster provides evidence for allele-specific mutation rates
    C Schlotterer
    Institut fur Tierzucht und Genetik, Vienna, Austria
    Mol Biol Evol 15:1269-74. 1998
  7. ncbi request reprint The evolution of molecular markers--just a matter of fashion?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Vienna, Austria
    Nat Rev Genet 5:63-9. 2004
  8. pmc Allele excess at neutrally evolving microsatellites and the implications for tests of neutrality
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Wien, Austria
    Proc Biol Sci 271:869-74. 2004
  9. pmc Highly structured Asian Drosophila melanogaster populations: a new tool for hitchhiking mapping?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Genetics 172:287-92. 2006
  10. ncbi request reprint Low abundance of Escherichia coli microsatellites is associated with an extremely low mutation rate
    C Schlotterer
    Institut fur Tierzucht und Genetik, VMU Wien, Josef Baumann Gasse 1, 1210 Vienna, Austria
    J Evol Biol 19:1671-6. 2006

Collaborators

Detail Information

Publications73

  1. ncbi request reprint Genetics. Where do male genes live?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Science 299:670-1. 2003
  2. pmc Nonrandom Wolbachia infection status of Drosophila melanogaster strains with different mtDNA haplotypes
    Maria D S Nunes
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, Vienna, Austria
    Mol Biol Evol 25:2493-8. 2008
    ..Although it is difficult to identify the evolutionary forces causing the global increase of wMel, the parallel sweep of Wolbachia and an mtDNA haplotype suggests a fitness advantage of the Wolbachia infection...
  3. pmc Gene expression analysis indicates extensive genotype-specific crosstalk between the conjugative F-plasmid and the E. coli chromosome
    Bettina Harr
    Institut fur Genetik, Universitat Koln, Zuelpicher Strasse 47, 50674 Koln, Germany
    BMC Microbiol 6:80. 2006
    ..Plasmids are an important component of the bacterial genome, but the crosstalk between genes encoded on the chromosome and on the plasmid is still poorly understood...
  4. pmc Survey of microsatellite clustering in eight fully sequenced species sheds light on the origin of compound microsatellites
    Robert Kofler
    University of Natural Resources and Applied Life Sciences, Department for Agrobiotechnology IFA Tulln, Institute of Biotechnology in Plant Production, Tulln, Austria
    BMC Genomics 9:612. 2008
    ..Until now, such composite microsatellites have not been investigated in a comprehensive manner...
  5. pmc PanGEA: identification of allele specific gene expression using the 454 technology
    Robert Kofler
    University of Natural Resources and Applied Life Sciences, Department for Agrobiotechnology, Institute for Plant Production Biotechnology Konrad Lorenz Str 20, A 3430 Tulln, Austria
    BMC Bioinformatics 10:143. 2009
    ..Sequencing of cDNA does not only provide an estimate of the absolute expression level, it can also be used for the identification of allele specific gene expression...
  6. ncbi request reprint High mutation rate of a long microsatellite allele in Drosophila melanogaster provides evidence for allele-specific mutation rates
    C Schlotterer
    Institut fur Tierzucht und Genetik, Vienna, Austria
    Mol Biol Evol 15:1269-74. 1998
    ..The allele-specific mutation rate of 3.0 x 10(-4) per generation is within the range of mammalian mutation rates. Future microsatellite analyses will have to account for the dramatic differences in allele-specific mutation rates...
  7. ncbi request reprint The evolution of molecular markers--just a matter of fashion?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Vienna, Austria
    Nat Rev Genet 5:63-9. 2004
  8. pmc Allele excess at neutrally evolving microsatellites and the implications for tests of neutrality
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Wien, Austria
    Proc Biol Sci 271:869-74. 2004
    ..As the latter are notoriously difficult to obtain for experimental data, we suggest that other statistics, such as lnRV, may be better suited to the identification of microsatellite loci subject to selection...
  9. pmc Highly structured Asian Drosophila melanogaster populations: a new tool for hitchhiking mapping?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Genetics 172:287-92. 2006
    ..We propose that the availability of D. melanogaster populations with high and low population structure provides a novel tool for the identification of ecologically important adaptations by hitchhiking mapping...
  10. ncbi request reprint Low abundance of Escherichia coli microsatellites is associated with an extremely low mutation rate
    C Schlotterer
    Institut fur Tierzucht und Genetik, VMU Wien, Josef Baumann Gasse 1, 1210 Vienna, Austria
    J Evol Biol 19:1671-6. 2006
    ..This result provides a possible explanation for the genome-wide low density of microsatellites in E. coli. Furthermore, we show that the F-plasmid induced microsatellite instability is independent of the mismatch repair pathway...
  11. ncbi request reprint Hitchhiking mapping--functional genomics from the population genetics perspective
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210, Vienna, Austria
    Trends Genet 19:32-8. 2003
    ..Furthermore, this 'hitchhiking mapping' could also help in the functional characterization of genomes...
  12. pmc A microsatellite-based multilocus screen for the identification of local selective sweeps
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Genetics 160:753-63. 2002
    ..The ln RV test statistic is applied to a data set of 94 loci typed in eight non-African and two African human populations...
  13. ncbi request reprint Genealogical inference of closely related species based on microsatellites
    C Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Genet Res 78:209-12. 2001
    ....
  14. ncbi request reprint Microsatellite analysis of Drosophila melanogaster populations along a microclimatic contrast at lower Nahel Oren canyon, Mount Carmel, Israel
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Vienna University of Veterinary Medicine, Josef Baumann Gasse 1, 1210 Vienna, Austria
    Mol Biol Evol 19:563-8. 2002
    ..melanogaster populations was low (F(ST) = 0.0012). Also a tree of individuals based on the proportion of shared alleles and a model-based clustering method provided no evidence for population substructuring...
  15. ncbi request reprint Single nucleotide polymorphisms derived from ancestral populations show no evidence for biased diversity estimates in Drosophila melanogaster
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Austria
    Mol Ecol 11:947-50. 2002
    ..This result suggests that diversity estimates based on SNPs from ancestral populations could provide a general strategy to avoid biased SNP diversity estimates. Finally, the potential of SNPs for nonmodel organisms is discussed...
  16. ncbi request reprint Microsatellite analysis indicates genetic differentiation of the neo-sex chromosomes in Drosophila americana americana
    C Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Wien, Austria
    Heredity (Edinb) 85:610-6. 2000
    ..a. americana and D. a. texana as well as between the neo-X and neo-Y chromosomes in D. a. americana. Nevertheless, levels of variability were similar among the neo-sex chromosomes, indicating a very recent origin...
  17. ncbi request reprint Evolutionary dynamics of microsatellite DNA
    C Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Vienna, Austria
    Chromosoma 109:365-71. 2000
    ..g., fragile X and Huntington's disease). A detailed understanding of the processes underlying microsatellite instability is therefore an important contribution toward a better understanding of these human neurodegenerative diseases...
  18. ncbi request reprint Drosophila virilis has long and highly polymorphic microsatellites
    C Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Vienna, Austria
    Mol Biol Evol 17:1641-6. 2000
    ..7 repeats vs. 12.2 repeats). Characterization of 11 microsatellite loci mapping to division 40-49 on the fourth chromosome of D. virilis indicated that D. virilis microsatellites are more variable than those of D. melanogaster...
  19. pmc African sequence variation accounts for most of the sequence polymorphism in non-African Drosophila melanogaster
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, A 1210 Vienna, Austria
    Genetics 170:1701-9. 2005
    ..Our results imply that the population structure and demographic past of African D. melanogaster populations need to be considered for the inference of footprints of selection in non-African populations...
  20. doi request reprint Contrasting patterns of natural variation in global Drosophila melanogaster populations
    Maria D S Nunes
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Austria
    Mol Ecol 17:4470-9. 2008
    ..In the light of the well-established African origin of D. melanogaster, our results cast severe doubts about the suitability of mtDNA for biogeographic inference in this model organism...
  21. pmc Two distinct modes of microsatellite mutation processes: evidence from the complete genomic sequences of nine species
    Daniel Dieringer
    Institut fur Tierzucht und Genetik, 1210 Wien, Austria
    Genome Res 13:2242-51. 2003
    ..When we introduced one additional mutation process, a length-independent slippage (indel slippage) operating at repeats with few repetitions, our computer simulations captured the observed pattern of microsatellite distribution...
  22. ncbi request reprint Population structure in African Drosophila melanogaster revealed by microsatellite analysis
    Daniel Dieringer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210 Wien Austria
    Mol Ecol 14:563-73. 2005
    ..Low, but significant levels of differentiation were observed for sub-Saharan D. melanogaster populations from West and East Africa...
  23. ncbi request reprint Nonneutral admixture of immigrant genotypes in African Drosophila melanogaster populations from Zimbabwe
    Maximilian Kauer
    Institut fur Tierzucht und Genetik, Vienna, Austria
    Mol Biol Evol 20:1329-37. 2003
    ..The higher number of European alleles on the third chromosome could be due to stronger selection against foreign alleles on the X chromosome or to more introgression of (beneficial) alleles on the third chromosome...
  24. ncbi request reprint Evidence for shared ancestral polymorphism rather than recurrent gene flow at microsatellite loci differentiating two hybridizing oaks (Quercus spp.)
    Graham Muir
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210, Wien, Austria
    Mol Ecol 14:549-61. 2005
    ..Based on our results we propose that the low genetic differentiation among these species results from shared ancestry rather than high rates of gene flow...
  25. ncbi request reprint Patterns of microsatellite variability in the Drosophila melanogaster complex
    Bettina Harr
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, 1210 Vienna, Austria
    Genetica 120:71-7. 2004
    ..melanogaster, D. simulans and D. sechellia, despite that the D. melanogaster and D. simulans population samples were of non-African origin and represented recently expanded populations...
  26. pmc Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles
    Pablo Orozco-terWengel
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    Mol Ecol 21:4931-41. 2012
    ..Our data thus suggest that the genomic response to selection can involve a large number of selected SNPs that show unexpectedly complex evolutionary trajectories, possibly due to nonadditive effects...
  27. pmc Expression profiling of Drosophila mitochondrial genes via deep mRNA sequencing
    Tatiana Teixeira Torres
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Vienna, Austria
    Nucleic Acids Res 37:7509-18. 2009
    ..Finally, we also identified several transcripts with a noncanonical structure, suggesting that processing of mitochondrial transcripts may be more complex than previously assumed...
  28. pmc No accelerated rate of protein evolution in male-biased Drosophila pseudoobscura genes
    Muralidhar Metta
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Genetics 174:411-20. 2006
    ..melanogaster genes did. If sexual selection is driving molecular evolution of male-biased genes, our data imply a radically different selection regime in D. pseudoobscura...
  29. doi request reprint Whole-genome sequences of two turkey adenovirus types reveal the existence of two unknown lineages that merit the establishment of novel species within the genus Aviadenovirus
    Ana Marek
    Clinic for Avian, Reptile and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine, Vienna, Austria
    J Gen Virol 95:156-70. 2014
    ..Our analyses suggest a common evolutionary origin of TAdV-5 and FAdV-1. ..
  30. pmc Estimating empirical codon hidden Markov models
    Nicola De Maio
    Institut für Populationsgenetik, Vetmeduni Vienna, Wien, Austria
    Mol Biol Evol 30:725-36. 2013
    ..The new LRTs are more conservative than the classical ones, having acceptable false-positive rates and reduced power...
  31. pmc E. coli microcosms indicate a tight link between predictability of ecosystem dynamics and diversity
    Marianne Imhof
    Institut fur Tierzucht und Genetik, Wien, Austria
    PLoS Genet 2:e103. 2006
    ..We conclude that system complexity provides a buffer against stochastic effects...
  32. pmc Hitchhiking mapping: a population-based fine-mapping strategy for adaptive mutations in Drosophilamelanogaster
    Bettina Harr
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, Veterinarplatz 1, 1210 Vienna, Austria
    Proc Natl Acad Sci U S A 99:12949-54. 2002
    ..Our study suggests that hitchhiking mapping is a universal approach for the identification of ecologically important mutations...
  33. ncbi request reprint Inference of chromosomal inversion dynamics from Pool-Seq data in natural and laboratory populations of Drosophila melanogaster
    Martin Kapun
    Institut für Populationsgenetik, Vetmeduni Vienna, Veterinarplatz 1, Vienna, A 1210, Austria Vienna Graduate School of Population Genetics, Iowa City, IA, 52242, USA
    Mol Ecol 23:1813-27. 2014
    ..The inversion markers developed here provide a versatile and robust tool for characterizing inversion frequencies and their dynamics in Pool-Seq data from diverse D. melanogaster populations...
  34. ncbi request reprint Microsatellite variation and differentiation in African and non-African populations of Drosophila simulans
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Wien, Austria
    Mol Ecol 15:3895-905. 2006
    ..Pairwise F(ST) analysis, however, indicated significant population differentiation between all eight populations surveyed. A significant signal for population reduction in cosmopolitan populations was found only for X-linked loci...
  35. pmc Genome-wide patterns of latitudinal differentiation among populations of Drosophila melanogaster from North America
    Daniel K Fabian
    Institut für Populationsgenetik, Vetmeduni Vienna, Veterinarplatz 1, A 1210, Vienna, Austria
    Mol Ecol 21:4748-69. 2012
    ....
  36. pmc Male-biased genes are overrepresented among novel Drosophila pseudoobscura sex-biased genes
    Muralidhar Metta
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Wien, Austria
    BMC Evol Biol 8:182. 2008
    ..The origin of functional innovation is among the key questions in biology. Recently, it has been shown that new genes could arise from non-coding DNA and that such novel genes are often involved in male reproduction...
  37. pmc PoPoolation DB: a user-friendly web-based database for the retrieval of natural polymorphisms in Drosophila
    Ram Vinay Pandey
    Institut für Populationsgenetik, Vetmeduni Vienna, Veterinarplatz 1, Vienna, Austria
    BMC Genet 12:27. 2011
    ....
  38. ncbi request reprint The first whole genome sequence of a Fowl adenovirus B strain enables interspecies comparisons within the genus Aviadenovirus
    Ana Marek
    Clinic for Avian, Reptile and Fish Medicine, Department for Farm Animals and Veterinary Public Health, Vetmeduni Vienna, Vienna, Austria
    Vet Microbiol 166:250-6. 2013
    ..With the completion of full genomes from all fowl adenovirus species, additional insights into the evolution of genus Aviadenovirus were obtained...
  39. pmc A genome-wide, fine-scale map of natural pigmentation variation in Drosophila melanogaster
    Héloïse Bastide
    Institut für Populationsgenetik, Vetmeduni Vienna, Wien, Austria
    PLoS Genet 9:e1003534. 2013
    ..While the Pool-GWAS approach suffers some limitations, its cost advantage facilitates replication and it can be applied to any non-model system with an available reference genome...
  40. ncbi request reprint Patterns of microsatellite variability among X chromosomes and autosomes indicate a high frequency of beneficial mutations in non-African D. simulans
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, Vienna, Austria
    Mol Biol Evol 21:1384-90. 2004
    ..simulans. We conclude that our data are not compatible with a neutral scenario. Thus, the reduced variability at X-linked loci is most likely caused by selective sweeps associated with the out-of-Africa habitat expansion of D. simulans...
  41. pmc Combining evidence of selection with association analysis increases power to detect regions influencing complex traits in dairy cattle
    Hermann Schwarzenbacher
    Lehrstuhl für Tierzucht, Technische Universitat Munchen, Hochfeldweg 1, 85376 Freising Weihenstephan, Germany
    BMC Genomics 13:48. 2012
    ....
  42. pmc Gowinda: unbiased analysis of gene set enrichment for genome-wide association studies
    Robert Kofler
    Institut für Populationsgenetik, Vetmeduni Vienna, Veterinarplatz 1, A 1210 Wien, Austria
    Bioinformatics 28:2084-5. 2012
    ..Since sufficient resolution for large datasets requires millions of permutations, we use multi-threading to keep computation times reasonable...
  43. pmc Linking great apes genome evolution across time scales using polymorphism-aware phylogenetic models
    Nicola De Maio
    Institut für Populationsgenetik, Vetmeduni Vienna, Wien, Austria
    Mol Biol Evol 30:2249-62. 2013
    ..Finally, our results are consistent with directional selection acting on coding sequences in relation to exonic splicing enhancers. ..
  44. pmc Intra-Specific Regulatory Variation in Drosophila pseudoobscura
    Anton Suvorov
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria Vienna Graduate School of Population Genetics, Vienna, Austria
    PLoS ONE 8:e83547. 2013
    ..Our results underline the importance of intra-specific analyses for the understanding of the evolution of gene expression. ..
  45. pmc Extensive paternal mtDNA leakage in natural populations of Drosophila melanogaster
    Maria D S Nunes
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    Mol Ecol 22:2106-17. 2013
    ..Our results indicate that evolutionary studies using mtDNA as a marker might be biased by paternal leakage in this species...
  46. pmc Genome-wide patterns of natural variation reveal strong selective sweeps and ongoing genomic conflict in Drosophila mauritiana
    Viola Nolte
    Institut für Populationsgenetik, Vetmeduni Vienna, 1210 Wien, Austria
    Genome Res 23:99-110. 2013
    ..Since this adaptive evolution is continuing after the split of D. mauritiana and Drosophila simulans, we conclude that genomic conflict is not restricted to short episodes, but rather an ongoing process in Drosophila...
  47. pmc Non-random genomic integration - an intrinsic property of retrogenes in Drosophila?
    Muralidhar Metta
    Institut für Populationsgenetik, Vetmeduni Vienna, Veterinarplatz 1, 1210 Wien, Austria
    BMC Evol Biol 10:114. 2010
    ..We scrutinized the evolutionary dynamics of retroposition by focusing on retrogenes for which the parental copy has degenerated...
  48. pmc African Drosophila melanogaster and D. simulans populations have similar levels of sequence variability, suggesting comparable effective population sizes
    Viola Nolte
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, A 1210 Wien, Austria
    Genetics 178:405-12. 2008
    ..simulans. Our observation of similar levels of variability of both species will have important implications for the interpretation of patterns of molecular evolution...
  49. pmc Detecting selective sweeps: a new approach based on hidden markov models
    Simon Boitard
    Institute of Statistics and Decision Support Systems, University of Vienna, Vienna, Austria
    Genetics 181:1567-78. 2009
    ..In the case of population bottlenecks, however, our methods frequently showed fewer false positives...
  50. pmc DistMap: a toolkit for distributed short read mapping on a Hadoop cluster
    Ram Vinay Pandey
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    PLoS ONE 8:e72614. 2013
    ..DistMap supports both paired-end and single-end reads thereby allowing the mapping of read data produced by different sequencing platforms. DistMap is available from http://code.google.com/p/distmap/ ..
  51. pmc PoPoolation2: identifying differentiation between populations using sequencing of pooled DNA samples (Pool-Seq)
    Robert Kofler
    Institut für Populationsgenetik, Vetmeduni Vienna, Veterinarplatz 1, A 1210 Wien, Austria
    Bioinformatics 27:3435-6. 2011
    ..The result may be visualized with the widely used Integrated Genomics Viewer...
  52. pmc Massive habitat-specific genomic response in D. melanogaster populations during experimental evolution in hot and cold environments
    Ray Tobler
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    Mol Biol Evol 31:364-75. 2014
    ..mauritiana and D. simulans, instead of D. melanogaster. ..
  53. pmc Allelic imbalance metre (Allim), a new tool for measuring allele-specific gene expression with RNA-seq data
    Ram Vinay Pandey
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    Mol Ecol Resour 13:740-5. 2013
    ..Then, a sequence-specific simulation tool estimates the residual mapping bias. Statistical tests for allelic imbalance are provided that can be used with the bias corrected RNA-seq data...
  54. ncbi request reprint Polymorphic microsatellites in Antirrhinum (Scrophulariaceae), a genus with low levels of nuclear sequence variability
    D Zwettler
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, A 1210 Vienna, Austria
    J Hered 93:217-21. 2002
    ..The highly self-compatible Antirrhinum majus ssp. cirrhigerum population has high levels of variability and no significant deviation from Hardy-Weinberg equilibrium, suggesting substantial rates of outcrossing...
  55. pmc Evaluation of different reference based annotation strategies using RNA-Seq - a case study in Drososphila pseudoobscura
    Nicola Palmieri
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    PLoS ONE 7:e46415. 2012
    ..Finally, we identified 99 additional new genes that are not represented in the current genome contigs of D. pseudoobscura, probably due to location in genomic regions that are difficult to assemble (e.g. heterochromatic regions)...
  56. pmc Nonsense-mediated decay enables intron gain in Drosophila
    Ashley Farlow
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Wien, Austria
    PLoS Genet 6:e1000819. 2010
    ..This mechanism reduces the sequence requirement imposed on novel introns and implies that the capacity of the spliceosome to recognize weak splice sites was a prerequisite for intron gain during eukaryotic evolution...
  57. pmc Gene expression profiling by massively parallel sequencing
    Tatiana Teixeira Torres
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Vienna, Austria
    Genome Res 18:172-7. 2008
    ..Our analyses suggest that the 454 technology has a large potential for expression profiling, and the high mapping accuracy indicates that it should be possible to compare expression profiles across species...
  58. pmc Contrasting seasonal niche separation between rare and abundant taxa conceals the extent of protist diversity
    Viola Nolte
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, A 1210 Vienna, Austria
    Mol Ecol 19:2908-15. 2010
    ..Consequently temporal sampling is basic for adequate diversity and species richness estimates...
  59. pmc Multiple hybridization events between Drosophila simulans and Drosophila mauritiana are supported by mtDNA introgression
    Maria D S Nunes
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Vienna, Austria
    Mol Ecol 19:4695-707. 2010
    ..simulans and D. mauritiana. Our results suggest that these species are exchanging genes more frequently than previously thought...
  60. ncbi request reprint Towards a molecular characterization of adaptation in local populations
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210, Wien, Austria
    Curr Opin Genet Dev 12:683-7. 2002
    ..Recent studies have shown that multilocus scans that compare different populations for several loci can identify genomic regions carrying a mutation that results in a local adaptation...
  61. pmc Genealogical lineage sorting leads to significant, but incorrect Bayesian multilocus inference of population structure
    Pablo Orozco-terWengel
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    Mol Ecol 20:1108-21. 2011
    ....
  62. ncbi request reprint Similar mating and sperm displacement patterns in two highly divergent D. simulans populations from Africa and Europe
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210 Wien, Austria
    Mol Ecol 14:1511-5. 2005
    ..The remating parameter alpha was similar in both populations (a = 1.3-1.4). No more than two distinct paternal genotypes per family were detected in each population...
  63. pmc PoPoolation: a toolbox for population genetic analysis of next generation sequencing data from pooled individuals
    Robert Kofler
    Institute of Population Genetics, Vetmeduni Vienna, Vienna, Austria
    PLoS ONE 6:e15925. 2011
    ..google.com/p/popoolation/. Furthermore, we evaluate the influence of mapping algorithms, sequencing errors, and read coverage on the accuracy of population genetic parameter estimates from pooled data...
  64. pmc Phenotypic plasticity in Drosophila pigmentation caused by temperature sensitivity of a chromatin regulator network
    Jean Michel Gibert
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Vienna, Austria
    PLoS Genet 3:e30. 2007
    ..Furthermore, the thermosensitivity of this network may be related to the high evolvability of several secondary sexual characters in the genus Drosophila...
  65. ncbi request reprint A major bristle QTL from a selected population of Drosophila uncovers the zinc-finger transcription factor poils-au-dos, a repressor of achaete-scute
    Jean Michel Gibert
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Dev Biol 288:194-205. 2005
    ..In addition, we show that pad interacts synergistically with the repressor hairy and with Dpp signaling in posterior and anterior regions of the notum, respectively...
  66. doi request reprint Two fiber genes of nearly equal lengths are a common and distinctive feature of Fowl adenovirus C members
    Ana Marek
    Clinic for Avian, Reptile and Fish Medicine, Department for Farm Animals and Veterinary Public Health, Vetmeduni Vienna, Veterinarplatz 1, 1210 Vienna, Austria
    Vet Microbiol 156:411-7. 2012
    ..Phylogenetic analyses provided insights about the evolution of fiber genes in avian adenoviruses and their genetic relationships...
  67. pmc The Genomic Signature of Splicing-Coupled Selection Differs between Long and Short Introns
    Ashley Farlow
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    Mol Biol Evol 29:21-4. 2012
    ..Together with an analysis of intron length and splice site strength, we observe that the genomic signature of splicing-coupled selection differs between long and short introns...
  68. pmc Host range and specificity of the Drosophila C virus
    Martin Kapun
    Institut für Populationsgenetik, Vetmeduni Vienna, Vienna, Austria
    PLoS ONE 5:e12421. 2010
    ..simulans, and artificial infections have been reported from several Drosophila species and other insects, it remains unclear to date whether DCV infections also occur naturally in other Drosophila species...
  69. pmc CANGS DB: a stand-alone web-based database tool for processing, managing and analyzing 454 data in biodiversity studies
    Ram Vinay Pandey
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, Vienna, Austria
    BMC Res Notes 4:227. 2011
    ..abstract:..
  70. ncbi request reprint Mismatch repair-driven mutational bias in D. melanogaster
    Bettina Harr
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, Austria
    Mol Cell 10:199-205. 2002
    ..melanogaster. When compared to other species, D. melanogaster has significantly shorter microsatellites. Our results suggest that the mismatch repair system may have an important role in shaping genome composition...
  71. pmc A single amino acid replacement in ETC2 shapes trichome patterning in natural Arabidopsis populations
    Julia Hilscher
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Vienna, Austria
    Curr Biol 19:1747-51. 2009
    ..This is consistent with the view that morphology can evolve by coding changes that can subtly modulate protein activity as well as cis-regulatory changes that alter expression patterns...
  72. pmc Mapping accuracy of short reads from massively parallel sequencing and the implications for quantitative expression profiling
    Nicola Palmieri
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Vienna, Austria
    PLoS ONE 4:e6323. 2009
    ..Reliable expression profiling by massively parallel sequencing depends crucially on the accuracy to which the reads could be mapped to the corresponding genes...
  73. pmc CANGS: a user-friendly utility for processing and analyzing 454 GS-FLX data in biodiversity studies
    Ram Vinay Pandey
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, Vienna, Austria
    BMC Res Notes 3:3. 2010
    ..A user-friendly software utility that carries out these steps is still lacking...