Christian Schlotterer

Summary

Affiliation: University of Veterinary Medicine
Country: Austria

Publications

  1. ncbi request reprint Similar mating and sperm displacement patterns in two highly divergent D. simulans populations from Africa and Europe
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210 Wien, Austria
    Mol Ecol 14:1511-5. 2005
  2. ncbi request reprint Towards a molecular characterization of adaptation in local populations
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210, Wien, Austria
    Curr Opin Genet Dev 12:683-7. 2002
  3. pmc African sequence variation accounts for most of the sequence polymorphism in non-African Drosophila melanogaster
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, A 1210 Vienna, Austria
    Genetics 170:1701-9. 2005
  4. ncbi request reprint Microsatellite variation and differentiation in African and non-African populations of Drosophila simulans
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Wien, Austria
    Mol Ecol 15:3895-905. 2006
  5. ncbi request reprint Patterns of microsatellite variability among X chromosomes and autosomes indicate a high frequency of beneficial mutations in non-African D. simulans
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, Vienna, Austria
    Mol Biol Evol 21:1384-90. 2004
  6. ncbi request reprint The evolution of molecular markers--just a matter of fashion?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Vienna, Austria
    Nat Rev Genet 5:63-9. 2004
  7. pmc Male-biased genes are overrepresented among novel Drosophila pseudoobscura sex-biased genes
    Muralidhar Metta
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Wien, Austria
    BMC Evol Biol 8:182. 2008
  8. pmc A genome-wide, fine-scale map of natural pigmentation variation in Drosophila melanogaster
    Héloïse Bastide
    Institut für Populationsgenetik, Vetmeduni Vienna, Wien, Austria
    PLoS Genet 9:e1003534. 2013
  9. pmc Non-random genomic integration - an intrinsic property of retrogenes in Drosophila?
    Muralidhar Metta
    Institut für Populationsgenetik, Vetmeduni Vienna, Veterinarplatz 1, 1210 Wien, Austria
    BMC Evol Biol 10:114. 2010
  10. ncbi request reprint Hitchhiking mapping--functional genomics from the population genetics perspective
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210, Vienna, Austria
    Trends Genet 19:32-8. 2003

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Similar mating and sperm displacement patterns in two highly divergent D. simulans populations from Africa and Europe
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210 Wien, Austria
    Mol Ecol 14:1511-5. 2005
    ..The remating parameter alpha was similar in both populations (a = 1.3-1.4). No more than two distinct paternal genotypes per family were detected in each population...
  2. ncbi request reprint Towards a molecular characterization of adaptation in local populations
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210, Wien, Austria
    Curr Opin Genet Dev 12:683-7. 2002
    ..Recent studies have shown that multilocus scans that compare different populations for several loci can identify genomic regions carrying a mutation that results in a local adaptation...
  3. pmc African sequence variation accounts for most of the sequence polymorphism in non-African Drosophila melanogaster
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, A 1210 Vienna, Austria
    Genetics 170:1701-9. 2005
    ..Our results imply that the population structure and demographic past of African D. melanogaster populations need to be considered for the inference of footprints of selection in non-African populations...
  4. ncbi request reprint Microsatellite variation and differentiation in African and non-African populations of Drosophila simulans
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Wien, Austria
    Mol Ecol 15:3895-905. 2006
    ..Pairwise F(ST) analysis, however, indicated significant population differentiation between all eight populations surveyed. A significant signal for population reduction in cosmopolitan populations was found only for X-linked loci...
  5. ncbi request reprint Patterns of microsatellite variability among X chromosomes and autosomes indicate a high frequency of beneficial mutations in non-African D. simulans
    Gerhard Schöfl
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, Vienna, Austria
    Mol Biol Evol 21:1384-90. 2004
    ..simulans. We conclude that our data are not compatible with a neutral scenario. Thus, the reduced variability at X-linked loci is most likely caused by selective sweeps associated with the out-of-Africa habitat expansion of D. simulans...
  6. ncbi request reprint The evolution of molecular markers--just a matter of fashion?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Vienna, Austria
    Nat Rev Genet 5:63-9. 2004
  7. pmc Male-biased genes are overrepresented among novel Drosophila pseudoobscura sex-biased genes
    Muralidhar Metta
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Wien, Austria
    BMC Evol Biol 8:182. 2008
    ..The origin of functional innovation is among the key questions in biology. Recently, it has been shown that new genes could arise from non-coding DNA and that such novel genes are often involved in male reproduction...
  8. pmc A genome-wide, fine-scale map of natural pigmentation variation in Drosophila melanogaster
    Héloïse Bastide
    Institut für Populationsgenetik, Vetmeduni Vienna, Wien, Austria
    PLoS Genet 9:e1003534. 2013
    ..While the Pool-GWAS approach suffers some limitations, its cost advantage facilitates replication and it can be applied to any non-model system with an available reference genome...
  9. pmc Non-random genomic integration - an intrinsic property of retrogenes in Drosophila?
    Muralidhar Metta
    Institut für Populationsgenetik, Vetmeduni Vienna, Veterinarplatz 1, 1210 Wien, Austria
    BMC Evol Biol 10:114. 2010
    ..We scrutinized the evolutionary dynamics of retroposition by focusing on retrogenes for which the parental copy has degenerated...
  10. ncbi request reprint Hitchhiking mapping--functional genomics from the population genetics perspective
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Josef Baumann Gasse 1, 1210, Vienna, Austria
    Trends Genet 19:32-8. 2003
    ..Furthermore, this 'hitchhiking mapping' could also help in the functional characterization of genomes...
  11. pmc Highly structured Asian Drosophila melanogaster populations: a new tool for hitchhiking mapping?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Genetics 172:287-92. 2006
    ..We propose that the availability of D. melanogaster populations with high and low population structure provides a novel tool for the identification of ecologically important adaptations by hitchhiking mapping...
  12. pmc Estimating empirical codon hidden Markov models
    Nicola De Maio
    Institut für Populationsgenetik, Vetmeduni Vienna, Wien, Austria
    Mol Biol Evol 30:725-36. 2013
    ..The new LRTs are more conservative than the classical ones, having acceptable false-positive rates and reduced power...
  13. pmc Genome-wide patterns of natural variation reveal strong selective sweeps and ongoing genomic conflict in Drosophila mauritiana
    Viola Nolte
    Institut für Populationsgenetik, Vetmeduni Vienna, 1210 Wien, Austria
    Genome Res 23:99-110. 2013
    ..Since this adaptive evolution is continuing after the split of D. mauritiana and Drosophila simulans, we conclude that genomic conflict is not restricted to short episodes, but rather an ongoing process in Drosophila...
  14. pmc African Drosophila melanogaster and D. simulans populations have similar levels of sequence variability, suggesting comparable effective population sizes
    Viola Nolte
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, A 1210 Wien, Austria
    Genetics 178:405-12. 2008
    ..simulans. Our observation of similar levels of variability of both species will have important implications for the interpretation of patterns of molecular evolution...
  15. ncbi request reprint Evidence for shared ancestral polymorphism rather than recurrent gene flow at microsatellite loci differentiating two hybridizing oaks (Quercus spp.)
    Graham Muir
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210, Wien, Austria
    Mol Ecol 14:549-61. 2005
    ..Based on our results we propose that the low genetic differentiation among these species results from shared ancestry rather than high rates of gene flow...
  16. pmc Gene expression profiling by massively parallel sequencing
    Tatiana Teixeira Torres
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Vienna, Austria
    Genome Res 18:172-7. 2008
    ..Our analyses suggest that the 454 technology has a large potential for expression profiling, and the high mapping accuracy indicates that it should be possible to compare expression profiles across species...
  17. pmc Phenotypic plasticity in Drosophila pigmentation caused by temperature sensitivity of a chromatin regulator network
    Jean Michel Gibert
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Vienna, Austria
    PLoS Genet 3:e30. 2007
    ..Furthermore, the thermosensitivity of this network may be related to the high evolvability of several secondary sexual characters in the genus Drosophila...
  18. pmc Allele excess at neutrally evolving microsatellites and the implications for tests of neutrality
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Josef Baumann Gasse 1, 1210 Wien, Austria
    Proc Biol Sci 271:869-74. 2004
    ..As the latter are notoriously difficult to obtain for experimental data, we suggest that other statistics, such as lnRV, may be better suited to the identification of microsatellite loci subject to selection...
  19. ncbi request reprint Genetics. Where do male genes live?
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Science 299:670-1. 2003
  20. ncbi request reprint Patterns of microsatellite variability in the Drosophila melanogaster complex
    Bettina Harr
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, 1210 Vienna, Austria
    Genetica 120:71-7. 2004
    ..melanogaster, D. simulans and D. sechellia, despite that the D. melanogaster and D. simulans population samples were of non-African origin and represented recently expanded populations...
  21. pmc Sequencing of pooled DNA samples (Pool-Seq) uncovers complex dynamics of transposable element insertions in Drosophila melanogaster
    Robert Kofler
    Institut für Populationsgenetik, Vetmeduni Vienna, Wien, Austria
    PLoS Genet 8:e1002487. 2012
    ..Finally, using our high-resolution TE abundance measurements, we identified 13 candidate positively selected TE insertions based on their high population frequencies and on low Tajima's D values in their neighborhoods...
  22. pmc Nonsense-mediated decay enables intron gain in Drosophila
    Ashley Farlow
    Institut für Populationsgenetik, Veterinärmedizinische Universität Wien, Wien, Austria
    PLoS Genet 6:e1000819. 2010
    ..This mechanism reduces the sequence requirement imposed on novel introns and implies that the capacity of the spliceosome to recognize weak splice sites was a prerequisite for intron gain during eukaryotic evolution...
  23. ncbi request reprint Polymorphic microsatellites in Antirrhinum (Scrophulariaceae), a genus with low levels of nuclear sequence variability
    D Zwettler
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, A 1210 Vienna, Austria
    J Hered 93:217-21. 2002
    ..The highly self-compatible Antirrhinum majus ssp. cirrhigerum population has high levels of variability and no significant deviation from Hardy-Weinberg equilibrium, suggesting substantial rates of outcrossing...
  24. ncbi request reprint Nonneutral admixture of immigrant genotypes in African Drosophila melanogaster populations from Zimbabwe
    Maximilian Kauer
    Institut fur Tierzucht und Genetik, Vienna, Austria
    Mol Biol Evol 20:1329-37. 2003
    ..The higher number of European alleles on the third chromosome could be due to stronger selection against foreign alleles on the X chromosome or to more introgression of (beneficial) alleles on the third chromosome...
  25. pmc Hitchhiking mapping: a population-based fine-mapping strategy for adaptive mutations in Drosophilamelanogaster
    Bettina Harr
    Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat, Veterinarplatz 1, 1210 Vienna, Austria
    Proc Natl Acad Sci U S A 99:12949-54. 2002
    ..Our study suggests that hitchhiking mapping is a universal approach for the identification of ecologically important mutations...
  26. ncbi request reprint Microsatellite analysis of Drosophila melanogaster populations along a microclimatic contrast at lower Nahel Oren canyon, Mount Carmel, Israel
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Vienna University of Veterinary Medicine, Josef Baumann Gasse 1, 1210 Vienna, Austria
    Mol Biol Evol 19:563-8. 2002
    ..melanogaster populations was low (F(ST) = 0.0012). Also a tree of individuals based on the proportion of shared alleles and a model-based clustering method provided no evidence for population substructuring...
  27. ncbi request reprint Mismatch repair-driven mutational bias in D. melanogaster
    Bettina Harr
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, Austria
    Mol Cell 10:199-205. 2002
    ..melanogaster. When compared to other species, D. melanogaster has significantly shorter microsatellites. Our results suggest that the mismatch repair system may have an important role in shaping genome composition...
  28. pmc A microsatellite-based multilocus screen for the identification of local selective sweeps
    Christian Schlotterer
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Genetics 160:753-63. 2002
    ..The ln RV test statistic is applied to a data set of 94 loci typed in eight non-African and two African human populations...
  29. pmc No accelerated rate of protein evolution in male-biased Drosophila pseudoobscura genes
    Muralidhar Metta
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, 1210 Wien, Austria
    Genetics 174:411-20. 2006
    ..melanogaster genes did. If sexual selection is driving molecular evolution of male-biased genes, our data imply a radically different selection regime in D. pseudoobscura...
  30. pmc Two distinct modes of microsatellite mutation processes: evidence from the complete genomic sequences of nine species
    Daniel Dieringer
    Institut fur Tierzucht und Genetik, 1210 Wien, Austria
    Genome Res 13:2242-51. 2003
    ..When we introduced one additional mutation process, a length-independent slippage (indel slippage) operating at repeats with few repetitions, our computer simulations captured the observed pattern of microsatellite distribution...
  31. pmc E. coli microcosms indicate a tight link between predictability of ecosystem dynamics and diversity
    Marianne Imhof
    Institut fur Tierzucht und Genetik, Wien, Austria
    PLoS Genet 2:e103. 2006
    ..We conclude that system complexity provides a buffer against stochastic effects...