Julia Romanova

Summary

Affiliation: University of Natural Resources and Applied Life Sciences
Country: Austria

Publications

  1. ncbi Rescue of influenza virus expressing GFP from the NS1 reading frame
    Christian Kittel
    Institute of Applied Microbiology, University of Natural Resources and Applied Life Sciences, A-1190 Vienna, Austria
    Virology 324:67-73. 2004
  2. ncbi The fight against new types of influenza virus
    Julia Romanova
    Green Hills Biotechnology GmbH, Vienna, Austria
    Biotechnol J 1:1381-92. 2006
  3. ncbi Distinct host range of influenza H3N2 virus isolates in Vero and MDCK cells is determined by cell specific glycosylation pattern
    Julia Romanova
    Institute of Applied Microbiology, University for Agricultural Sciences, Muthgasse 18B, A 1190 Vienna, Austria
    Virology 307:90-7. 2003
  4. ncbi Live cold-adapted influenza A vaccine produced in Vero cell line
    Julia Romanova
    Institute of Applied Microbiology, University of Natural Resources and Applied Life Sciences, Muthgasse 18B, A 1190 Vienna, Austria
    Virus Res 103:187-93. 2004
  5. ncbi Live attenuated influenza virus expressing human interleukin-2 reveals increased immunogenic potential in young and aged hosts
    Boris Ferko
    Institute of Applied Microbiology, University of Natural Resources and Applied Life Sciences, Muthgasse 18B, A-1190 Vienna, Austria
    J Virol 80:11621-7. 2006
  6. ncbi Influenza virus NS vectors expressing the mycobacterium tuberculosis ESAT-6 protein induce CD4+ Th1 immune response and protect animals against tuberculosis challenge
    Sabine Sereinig
    Institute of Applied Microbiology, Muthgasse 18, 1190 Vienna, Austria
    Clin Vaccine Immunol 13:898-904. 2006
  7. ncbi Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes
    Boris Ferko
    Institute of Applied Microbiology, Muthgasse 18B, A 1190 Vienna, Austria
    J Virol 78:13037-45. 2004
  8. ncbi Generation of an influenza A virus vector expressing biologically active human interleukin-2 from the NS gene segment
    Christian Kittel
    Institute of Applied Microbiology, Muthgasse 18B, A-1190 Vienna, Austria
    J Virol 79:10672-7. 2005
  9. ncbi Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1beta and 18
    Jana Stasakova
    Institute of Applied Microbiology, University of Natural Resources and Applied Life Sciences, Muthgasse 18B, A-1190 Vienna, Austria
    J Gen Virol 86:185-95. 2005
  10. ncbi Receptor-binding properties of modern human influenza viruses primarily isolated in Vero and MDCK cells and chicken embryonated eggs
    Larisa Mochalova
    Shemyakin Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia
    Virology 313:473-80. 2003

Collaborators

  • B Ferko
  • Alexandra S Gambaryan
  • Christian Kittel
  • Sabine Sereinig
  • Andrej Egorov
  • Hermann Katinger
  • Jana Stasakova
  • Larisa Mochalova
  • Oleg Kiselev
  • Natalia Zabolotnyh
  • Tatiana Vinogradova
  • Marina Stukova
  • Gabriela Stiegler
  • Regina Voglauer
  • Martina Kurz
  • Andrea Wolkerstorfer
  • Alexander Chinarev
  • Herman Katinger
  • Alexander Tuzikov
  • Dietmar Katinger
  • Nicolai Bovin

Detail Information

Publications10

  1. ncbi Rescue of influenza virus expressing GFP from the NS1 reading frame
    Christian Kittel
    Institute of Applied Microbiology, University of Natural Resources and Applied Life Sciences, A-1190 Vienna, Austria
    Virology 324:67-73. 2004
    ..Although a rather long sequence of 275 aa was inserted into the NS1 reading frame, the rescued recombinant vector appeared to be genetically stable while passaging in Vero cells and was able to replicate in PKR knockout mice...
  2. ncbi The fight against new types of influenza virus
    Julia Romanova
    Green Hills Biotechnology GmbH, Vienna, Austria
    Biotechnol J 1:1381-92. 2006
    ..The effectiveness of existing antivirals as well as vaccines for humans and birds are reviewed...
  3. ncbi Distinct host range of influenza H3N2 virus isolates in Vero and MDCK cells is determined by cell specific glycosylation pattern
    Julia Romanova
    Institute of Applied Microbiology, University for Agricultural Sciences, Muthgasse 18B, A 1190 Vienna, Austria
    Virology 307:90-7. 2003
    ....
  4. ncbi Live cold-adapted influenza A vaccine produced in Vero cell line
    Julia Romanova
    Institute of Applied Microbiology, University of Natural Resources and Applied Life Sciences, Muthgasse 18B, A 1190 Vienna, Austria
    Virus Res 103:187-93. 2004
    ..Both vaccine strains were used for immunization of young adult volunteers in a limited clinical trial and appeared to be safe, well tolerated and immunogenic after intranasal administration...
  5. ncbi Live attenuated influenza virus expressing human interleukin-2 reveals increased immunogenic potential in young and aged hosts
    Boris Ferko
    Institute of Applied Microbiology, University of Natural Resources and Applied Life Sciences, Muthgasse 18B, A-1190 Vienna, Austria
    J Virol 80:11621-7. 2006
    ..Our findings emphasize the potential of reverse genetics to improve the efficacy of live influenza vaccines, thus rendering them more suitable for high-risk age groups...
  6. ncbi Influenza virus NS vectors expressing the mycobacterium tuberculosis ESAT-6 protein induce CD4+ Th1 immune response and protect animals against tuberculosis challenge
    Sabine Sereinig
    Institute of Applied Microbiology, Muthgasse 18, 1190 Vienna, Austria
    Clin Vaccine Immunol 13:898-904. 2006
    ..tuberculosis-specific Th1 immune response in mice. Moreover, intranasal immunization of mice and guinea pigs with such vectors induced protection against mycobacterial challenge, similar to that induced by BCG vaccination...
  7. ncbi Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes
    Boris Ferko
    Institute of Applied Microbiology, Muthgasse 18B, A 1190 Vienna, Austria
    J Virol 78:13037-45. 2004
    ..These findings indicate that a targeted modification of the RNA-binding domain of the NS1 protein is a valuable technique to generate replication-deficient, but immunogenic influenza virus vaccines...
  8. ncbi Generation of an influenza A virus vector expressing biologically active human interleukin-2 from the NS gene segment
    Christian Kittel
    Institute of Applied Microbiology, Muthgasse 18B, A-1190 Vienna, Austria
    J Virol 79:10672-7. 2005
    ..These results indicate that influenza viruses could be engineered for the expression of biologically active molecules such as cytokines for immune modulation purposes...
  9. ncbi Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1beta and 18
    Jana Stasakova
    Institute of Applied Microbiology, University of Natural Resources and Applied Life Sciences, Muthgasse 18B, A-1190 Vienna, Austria
    J Gen Virol 86:185-95. 2005
    ....
  10. ncbi Receptor-binding properties of modern human influenza viruses primarily isolated in Vero and MDCK cells and chicken embryonated eggs
    Larisa Mochalova
    Shemyakin Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia
    Virology 313:473-80. 2003
    ..These HA mutations disturb the observed strict 6'SLN specificity of recent human influenza viruses...